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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 250 departures available from fifteen of the world's leading cruise lines.
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4 Days
32 Days
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116 Cruises (250 Cruise Departures)
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Jun 2028 to Aug 2028
Visit: Italy, Malta, Montenegro, Croatia, Greece, Sicily, Spain
Exclusive Savings
Inside
$4,261
Oceanview
$4,954
Balcony
$5,597
Suite
$10,894
From
A$4,261
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
$1,813
Oceanview
$1,813
Balcony
$2,229
Suite
$4,367
From
A$1,813
Per Person
View Trip
10 Day Mediterranean Rivieras: Rome to Barcelona with Scenic
New ReleaseCruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 04 October 2028
Visit: Italy, Corsica, Monaco, France, Spain
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,183
Suite
$20,358
From
A$17,183
Save 4,812
Per Person
View Trip
9 Day Knights & Sunsets with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,117
Suite
$13,371
From
A$12,117
Save 2,223
Per Person
View Trip
11 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2027
Visit: Italy, France, Corsica, Monaco, Spain
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,602
Suite
$20,874
From
A$14,602
Save 298
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 29 October 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$847
Oceanview
$946
Balcony
$1,223
Suite
$1,392
From
A$847
Per Person
View Trip
8 Day A Journey Through Fortresses, Medinas and Balearic Splendour with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 02 January 2028
Visit: Italy, Sicily, Malta, Tunisia, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,840
From
A$6,840
Save 140
Per Person
View Trip
12 Day Idyllic Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 13 September 2028
Visit: Italy, Sardinia, Corsica, Spain
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,829
Suite
$23,710
From
A$19,829
Save 5,866
Per Person
View Trip
16 Day Mediterranean Pilgrimage with Regent Seven Seas
Cruise

16 Days (15 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,644
Suite
$22,153
From
A$19,644
Save 2,356
Per Person
View Trip
8 Day A Journey Of Mediterranean Wonders From Ancient Secrets To Modren Buzzing Vibes with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visit: Italy, Monaco, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$9,800
From
A$9,800
Save 200
Per Person
View Trip
10 Day Fairytales Afloat with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 03 September 2027
Visit: Italy, Sicily, Sardinia, Corsica, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,306
Suite
$8,420
From
A$5,306
Save 2,124
Per Person
View Trip
21 Day Ode On A Grecian Journey with Oceania Cruises
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 July 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,499
Suite
$20,143
From
A$12,499
Save 2,301
Per Person
View Trip
11 Day A Journey Of Inspirational Isles & Spectacular Horizons with Explora Journeys
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 04 August 2028
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,716
From
A$10,716
Save 219
Per Person
View Trip
7 Day A Journey Of Sunset Shores & Mediterranean Icons with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2027
Visit: Italy, Corsica, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,918
From
A$7,918
Save 162
Per Person
View Trip
8 Day A Journey Through Italian Treasures & French Riviera Elegance with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: May 2027 to Sep 2027
Visit: Italy, Corsica, Monaco, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,982
From
A$6,982
Save 172
Per Person
View Trip
17 Day France, Italy, Tunisia, Monaco & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+4 more), Sicily, Monaco, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,597
Suite
$26,593
From
A$17,597
Save 337
Per Person
View Trip
8 Day Yacht Harbors Of The Cote D'azur with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Jul 2028 to Sep 2028
Visit: Italy, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,040
Suite
$11,921
From
A$8,040
Save 149
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,182
Suite
$1,598
From
A$1,182
Per Person
View Trip
11 Day Elegant Arrivals with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 11 July 2028
Visit: Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,387
Suite
$20,984
From
A$18,387
Save 2,343
Per Person
View Trip
8 Day A Journey Of Riviera Glamour & Island Serenity with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 15 April 2028
Visit: Italy, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,409
From
A$6,409
Save 131
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,338
Suite
$14,419
From
A$9,338
Save 181
Per Person
View Trip
8 Day Riviera Radiance with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 October 2027
Visit: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,429
Suite
$6,388
From
A$4,429
Save 2,101
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departures: May 2027 to Sep 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,508
Oceanview
$1,949
Balcony
$2,366
Suite
$3,296
From
A$1,508
Save 958
Per Person
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$12,269
Balcony
$13,080
Suite
$21,256
From
A$12,269
Save 1,641
Per Person
View Trip
10 Day Greece & Italy Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Mariner of the Seas
Departure: 28 August 2027
Visit: Italy, Greece, Sicily, Spain
Exclusive Savings
Inside
$2,164
Oceanview
$2,752
Balcony
$3,201
Suite
$5,598
From
A$2,164
Save 1,103
Per Person
View Trip
10 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 28 February 2028
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,385
Suite
$8,014
From
A$5,385
Save 2,125
Per Person
View Trip
8 Day A Journey Through Italy's Rich Heritage to Catalan Elegance with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 19 December 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,262
From
A$7,262
Save 148
Per Person
View Trip
18 Day Sun, Sea & Saffron with Regent Seven Seas
Cruise

18 Days (17 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 05 July 2028
Visit: Italy, Sicily, Croatia, Slovenia (+4 more), Montenegro, Greece, Malta, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$30,490
Suite
$32,303
From
A$30,490
Save 2,560
Per Person
View Trip
10 Day Pasta To Paella with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 April 2028
Visit: Italy, Sardinia, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,608
Suite
$9,517
From
A$5,608
Save 2,132
Per Person
View Trip
10 Day A Journey Of Spirited Mediterranean Cities & Sunlit Islands with Explora Journeys
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jul 2027 to Aug 2027
Visit: Italy, Corsica, Monaco, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,448
From
A$7,448
Save 162
Per Person
View Trip
Results: 61-90 of 116

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