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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 251 departures available from fifteen of the world's leading cruise lines.
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117 Cruises (251 Cruise Departures)
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Aug 2026 to Oct 2027
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,838
Oceanview
$3,571
Balcony
$4,185
Suite
$4,917
From
A$2,838
Per Person
View Trip
9 Day A Journey From Rugged Landscapes To Cosmopolitan Allure with Explora Journeys
Cruise
 (1)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 15 May 2028
Visit: Italy, Corsica, Monaco, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,909
From
A$6,909
Save 141
Per Person
View Trip
8 Day A Journey Of Southern European Legends, Flavours & Ageless Allure with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 06 June 2028
Visit: Italy, Corsica, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,595
From
A$6,595
Save 135
Per Person
View Trip
11 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2027
Visit: Italy, France, Corsica, Monaco, Spain
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,602
Suite
$20,874
From
A$14,602
Save 298
Per Person
View Trip
10 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 28 February 2028
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,385
Suite
$8,014
From
A$5,385
Save 2,125
Per Person
View Trip
8 Day Florence, Monte Carlo & Southern France with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visit: Italy, Monaco, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,040
Suite
$19,771
From
A$8,040
Save 149
Per Person
View Trip
10 Day A Journey Of Spirited Mediterranean Cities & Sunlit Islands with Explora Journeys
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jul 2027 to Aug 2027
Visit: Italy, Corsica, Monaco, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,448
From
A$7,448
Save 162
Per Person
View Trip
10 Day Fairytales Afloat with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 03 September 2027
Visit: Italy, Sicily, Sardinia, Corsica, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,306
Suite
$8,420
From
A$5,306
Save 2,124
Per Person
View Trip
11 Day Artists & Aristocrats with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 07 November 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,608
Suite
$9,539
From
A$6,608
Save 2,162
Per Person
View Trip
17 Day An Extended Journey Of Island Chic & Riviera Glamour with Explora Journeys
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visit: Italy, Monaco, France, Spain, Sicily
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$20,203
From
A$20,203
Save 412
Per Person
View Trip
8 Day Yacht Harbors Of The Cote D'azur with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Jul 2028 to Sep 2028
Visit: Italy, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,040
Suite
$11,921
From
A$8,040
Save 149
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 29 October 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$847
Oceanview
$946
Balcony
$1,223
Suite
$1,392
From
A$847
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 July 2026
Visit: Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,913
From
A$7,913
Save 162
Per Person
View Trip
9 Day Monaco, Italy, France & Spain with Seabourn
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 June 2027
Visit: Italy, Monaco, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,756
Suite
$13,171
From
A$8,756
Save 168
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visit: Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,791
From
A$7,791
Save 159
Per Person
View Trip
9 Day Knights & Sunsets with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,117
Suite
$13,371
From
A$12,117
Save 2,223
Per Person
View Trip
8 Day Yacht Harbors Of The Cote D'azur with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 03 June 2028
Visit: Italy, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,010
Suite
$13,597
From
A$9,010
Save 169
Per Person
View Trip
8 Day Riviera Radiance with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 October 2027
Visit: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,429
Suite
$6,388
From
A$4,429
Save 2,101
Per Person
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 October 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Last Minute Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,163
Suite
$20,188
From
A$9,163
Save 187
Per Person
View Trip
10 Day Latin Languages Of Love with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 March 2028
Visit: Italy, Sicily, Sardinia, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,453
Suite
$9,371
From
A$5,453
Save 2,127
Per Person
View Trip
11 Day A Journey Of Inspirational Isles & Spectacular Horizons with Explora Journeys
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 04 August 2028
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,716
From
A$10,716
Save 219
Per Person
View Trip
10 Day Fountains To Flamenco with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 09 November 2027
Visit: Italy, Sardinia, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,053
Suite
$9,002
From
A$6,053
Save 2,147
Per Person
View Trip
18 Day Sun, Sea & Saffron with Regent Seven Seas
Cruise

18 Days (17 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 05 July 2028
Visit: Italy, Sicily, Croatia, Slovenia (+4 more), Montenegro, Greece, Malta, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$30,490
Suite
$32,303
From
A$30,490
Save 2,560
Per Person
View Trip
10 Day Glories Of The Adriatic with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 01 April 2029
Visit: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,293
Suite
$8,746
From
A$5,293
Save 2,147
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,338
Suite
$14,419
From
A$9,338
Save 181
Per Person
View Trip
17 Day France, Italy, Tunisia, Monaco & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+4 more), Sicily, Monaco, France, Spain
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,597
Suite
$26,593
From
A$17,597
Save 337
Per Person
View Trip
8 Day A Journey Through Italian Treasures & French Riviera Elegance with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: May 2027 to Sep 2027
Visit: Italy, Corsica, Monaco, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,982
From
A$6,982
Save 172
Per Person
View Trip
8 Day A Journey Through Riviera Reverie & Centres Of Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 02 October 2028
Visit: Italy, Corsica, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,982
From
A$6,982
Save 143
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 16 August 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,602
Oceanview
$2,010
Balcony
$2,389
Suite
$3,678
From
A$1,602
Save 897
Per Person
View Trip
11 Day Elegant Arrivals with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 11 July 2028
Visit: Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,387
Suite
$20,984
From
A$18,387
Save 2,343
Per Person
View Trip
Results: 61-90 of 117

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