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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? May and September are the most popular months to cruise between Rome and Barcelona and there are 277 departures available from sixteen of the world's leading cruise lines.
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118 Cruises (277 Departures)
118 Cruises (277 Departures)
Departures
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Duration
3 Days
32 Days
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Price
$300pp
$34,125pp
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17 Day France, Italy, Tunisia, Monaco & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Barcelona
Operator: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visits: Italy, Corsica, Sardinia, Tunisia +4 more, Sicily, Monaco, France, Spain
Exclusive Savings
Balcony
$23,834
Suite
-
From (Per Person)
A$23,834
Save 464
Per Person
View Trip
8 Day A Journey Through Italian Treasures & French Riviera Elegance with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora I
Departures: May 2027 to Sep 2027
Visits: Italy, Corsica, Monaco, France, Spain
Exclusive Savings
Suite
$6,860
From (Per Person)
A$6,860
Save 162
Per Person
View Trip
11 Day Western Mediterranean Cruise From Rome To Barcelona with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Rome to Barcelona
Operator: Norwegian Cruise Line
Ship: Norwegian Dawn
Departure: 29 April 2027
Visits: Italy, Sicily, Malta, Tunisia, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$2,669
Oceanview
$3,056
Balcony
$4,723
Suite
$4,888
From (Per Person)
A$2,669
Per Person
View Trip
8 Day Amalfi Coast, Africa & Iberia with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Viking
Ships: Viking Astrea, Viking Leda +8 more, Viking Libra, Viking Lyra, Viking Neptune, Viking Saturn, Viking Star, Viking Vega, Viking Vela, Viking Vesta
Departures: Oct 2026 to Jun 2029
Visits: Italy, Sicily, Tunisia, Sardinia, Spain
Exclusive Savings
Balcony
$4,748
Suite
$9,109
From (Per Person)
A$4,748
Save 1,421
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Suite
$7,649
From (Per Person)
A$7,649
Save 156
Per Person
View Trip
8 Day A Journey Through Riviera Reverie & Centres Of Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora VI
Departure: 02 October 2028
Visits: Italy, Corsica, France, Spain
Exclusive Savings
Suite
$6,517
From (Per Person)
A$6,517
Save 133
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$11,278
Suite
$19,706
From (Per Person)
A$11,278
Save 220
Per Person
View Trip
11 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Operator: Silversea
Ship: Silver Ray
Departure: 29 May 2027
Visits: Italy, France, Corsica, Monaco, Spain
Exclusive Savings
Balcony
$16,327
Suite
$21,913
From (Per Person)
A$16,327
Save 333
Per Person
View Trip
13 Day Masterpiece At Sea with Regent Seven Seas
Cruise

13 Days (12 Nights) Rome to Barcelona
Operator: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 06 October 2028
Visits: Italy, Sicily, Sardinia, Corsica, France, Spain
Exclusive Savings
Balcony
$16,987
Suite
$19,858
From (Per Person)
A$16,987
Save 2,313
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Barcelona
Operator: MSC Cruises
Ship: MSC Sinfonia
Departure: 29 October 2026
Visits: Italy, Spain
Exclusive Savings
Inside
$457
Oceanview
$556
Balcony
$833
Suite
$1,002
From (Per Person)
A$457
Per Person
View Trip
9 Day Knights & Sunsets with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Barcelona
Operator: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Balcony
$12,118
Suite
$13,372
From (Per Person)
A$12,118
Save 2,222
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Operator: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visits: Italy, France, Spain
Exclusive Savings
Inside
$546
Oceanview
$546
Balcony
$596
Suite
$1,596
From (Per Person)
A$546
Per Person
View Trip
15 Day Maritime Memories In The Med with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Barcelona
Operator: Oceania
Ship: Oceania Allura
Departure: 03 January 2028
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Morocco
Your World Inclusions
Exclusive Savings
Balcony
$6,827
Suite
$11,939
From (Per Person)
A$6,827
Save 2,153
Per Person
View Trip
10 Day A Journey Of Spirited Mediterranean Cities & Sunlit Islands with Explora Journeys
Cruise

10 Days (9 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora I
Departures: Jul 2027 to Aug 2027
Visits: Italy, Corsica, Monaco, France, Spain
Exclusive Savings
Suite
$6,982
From (Per Person)
A$6,982
Save 152
Per Person
View Trip
11 Day Italian & Iberian Escapade with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Barcelona
Operator: Oceania
Ship: Oceania Allura
Departure: 07 February 2029
Visits: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$4,761
Suite
$8,408
From (Per Person)
A$4,761
Save 2,129
Per Person
View Trip
10 Day Greece & Italy Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Rome to Barcelona
Operator: Royal Caribbean
Ship: Mariner of the Seas
Departure: 28 August 2027
Visits: Italy, Greece, Sicily, Spain
Exclusive Savings
Inside
$1,956
Oceanview
$2,463
Balcony
$2,840
Suite
$5,474
From (Per Person)
A$1,956
Save 1,006
Per Person
View Trip
8 Day Riviera Reverie with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 30 September 2027
Visits: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,576
Suite
$16,635
From (Per Person)
A$15,576
Save 2,294
Per Person
View Trip
11 Day Artists & Aristocrats with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Barcelona
Operator: Oceania
Ship: Oceania Allura
Departure: 07 November 2026
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Exclusive Savings
Balcony
$4,934
Suite
-
From (Per Person)
A$4,934
Save 6,236
Per Person
View Trip
11 Day Spotlight On Foley Family Wines with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Operator: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 24 March 2027
Visits: Italy, France, Spain
Exclusive Savings
Balcony
$15,748
Suite
$16,875
From (Per Person)
A$15,748
Save 2,292
Per Person
View Trip
12 Day Spotlight On Wine With Steven Honig with Regent Seven Seas
Cruise

12 Days (11 Nights) Rome to Barcelona
Operator: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 11 October 2027
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$8,405
Suite
$9,428
From (Per Person)
A$8,405
Save 8,975
Per Person
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Operator: Silversea
Ship: Silver Ray
Departure: 18 October 2026
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Balcony
$11,971
Suite
$20,188
From (Per Person)
A$11,971
Save 5,479
Per Person
View Trip
10 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Operator: Oceania
Ship: Oceania Allura
Departure: 28 February 2028
Visits: Italy, Sicily, Sardinia, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$5,385
Suite
$8,014
From (Per Person)
A$5,385
Save 2,125
Per Person
View Trip
8 Day A Journey Of Shimmering Shores & Timeless Mediterranean Treasures with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora I
Departures: Aug 2026 to Sep 2026
Visits: Italy, Corsica, France, Spain
Exclusive Savings
Suite
$11,564
From (Per Person)
A$11,564
Save 683
Per Person
View Trip
8 Day Florence, Monte Carlo & Southern France with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$9,225
Suite
$26,767
From (Per Person)
A$9,225
Save 173
Per Person
View Trip
9 Day Monaco, Italy, France & Spain with Seabourn
Cruise

9 Days (8 Nights) Rome to Barcelona
Operator: Seabourn
Ship: Seabourn Ovation
Departure: 29 June 2027
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$11,965
Suite
$15,885
From (Per Person)
A$11,965
Save 233
Per Person
View Trip
8 Day A Journey Of Mediterranean Wonders From Ancient Secrets To Modren Buzzing Vibes with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Suite
$8,844
From (Per Person)
A$8,844
Save 181
Per Person
View Trip
10 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise

10 Days (9 Nights) Rome to Barcelona
Operator: Silversea
Ship: Silver Ray
Departure: 19 September 2027
Visits: Italy, Corsica, France, Spain
Exclusive Savings
Balcony
$9,643
Suite
$18,032
From (Per Person)
A$9,643
Save 2,657
Per Person
View Trip
8 Day Riviera Radiance with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Operator: Oceania
Ship: Oceania Allura
Departure: 22 October 2027
Visits: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$4,429
Suite
$6,388
From (Per Person)
A$4,429
Save 2,101
Per Person
View Trip
10 Day Best Of Italy & Spain Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Operator: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 15 May 2027
Visits: Italy, Sicily, Sardinia, Spain
Exclusive Savings
Inside
$1,411
Oceanview
$1,976
Balcony
$2,182
Suite
$6,499
From (Per Person)
A$1,411
Save 898
Per Person
View Trip
7 Day A Journey Of Sunset Shores & Mediterranean Icons with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora I
Departure: 08 June 2027
Visits: Italy, Corsica, Spain
Exclusive Savings
Suite
$7,423
From (Per Person)
A$7,423
Save 152
Per Person
View Trip
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