Cruises from Italy to Spain

Are you looking for a cruise from Italy to Spain? June is the most popular month to cruise between Italy and Spain and there are 395 departures available from eighteen of the world's leading cruise lines.
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193 Cruises (395 Departures)
193 Cruises (395 Departures)
Departures
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Duration
3 Days
32 Days
Start & End Cities
Ship Size
Ship Features
Operators
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Price
$200pp
$55,125pp
Countries
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Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Operator: Viking
Departures: Nov 2026 to Aug 2029
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$5,826
Suite
$6,414
From (Per Person)
A$5,826
Save 1,371
Per Person
Cruise
 (1)

13 Days (12 Nights) Venice to Barcelona
Operator: Viking
Departures: Mar 2027 to Jul 2029
Visits: Italy, Croatia, Greece, Monaco, France, Spain
Exclusive Savings
Balcony
$11,069
Suite
$15,283
From (Per Person)
A$11,069
Save 316
Per Person
Cruise
 (1)

12 Days (11 Nights) Rome to Barcelona
Operator: Celebrity Cruises
Departure: 27 October 2028
Visits: Italy, Sicily, Greece, Malta, Spain
Exclusive Savings
Inside
$2,999
Oceanview
$3,340
Balcony
$4,012
Suite
$8,663
From (Per Person)
A$2,999
Save 2,035
Per Person
Cruise
 (9)

8 Days (7 Nights) Rome to Barcelona
Operator: Azamara
Departure: 27 May 2027
Visits: Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,330
Oceanview
$3,811
Balcony
$5,026
Suite
$8,064
From (Per Person)
A$3,330
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora II
Departure: 06 June 2028
Visits: Italy, Corsica, Spain
Exclusive Savings
Suite
$5,713
From (Per Person)
A$5,713
Save 117
Per Person
Cruise
 (2)

12 Days (11 Nights) Rome to Las Palmas de Gran Canaria
Operator: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visits: Italy, Spain, Portugal
Exclusive Savings
Inside
$1,213
Oceanview
$1,401
Balcony
$1,649
Suite
$3,450
From (Per Person)
A$1,213
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Operator: Silversea
Ship: Silver Nova
Departure: 07 November 2027
Visits: Italy, France, Spain
Exclusive Savings
Balcony
$8,428
Suite
$9,947
From (Per Person)
A$8,428
Save 872
Per Person
Cruise
 (9)

11 Days (10 Nights) Rome to Barcelona
Operator: Azamara
Departure: 03 March 2027
Visits: Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,779
Oceanview
$4,151
Balcony
$3,553
Suite
$5,151
From (Per Person)
A$2,779
Per Person
Cruise
 (3)

32 Days (31 Nights) Rome to Barcelona
Operator: Princess
Departure: 05 August 2028
Visits: Italy, Corsica, Malta, Montenegro +5 more, Croatia, Greece, Cyprus, Turkey, Spain
Exclusive Savings
Inside
$7,026
Oceanview
-
Balcony
$8,016
Suite
$10,907
From (Per Person)
A$7,026
Per Person
Cruise
 (6)

8 Days (7 Nights) Rome to Barcelona
Operator: Azamara
Departure: 04 December 2027
Visits: Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,408
Oceanview
$2,800
Balcony
$3,594
Suite
$5,348
From (Per Person)
A$2,408
Per Person
Cruise
 (1)

10 Days (9 Nights) Bologna to Barcelona
Departure: 21 July 2027
Visits: Italy, Croatia, Montenegro, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$4,443
Oceanview
$4,682
Balcony
$6,007
Suite
$7,703
From (Per Person)
A$4,443
Per Person
Cruise
 (1)

10 Days (9 Nights) Venice to Barcelona
Operator: Oceania
Departures: Apr 2027 to Jun 2027
Visits: Italy, Croatia, Montenegro, Greece, Sicily, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$3,597
Oceanview
$4,149
Balcony
$6,060
Suite
$8,805
From (Per Person)
A$3,597
Save 2,104
Per Person
Cruise
 (3)

22 Days (21 Nights) Rome to Barcelona
Operator: Princess
Departure: 16 May 2028
Visits: Italy, Croatia, Montenegro, Greece, Turkey, Malta, Spain
Exclusive Savings
Inside
$5,535
Oceanview
$6,684
Balcony
$6,684
Suite
$9,277
From (Per Person)
A$5,535
Per Person
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Operator: Cunard
Departure: 13 August 2027
Visits: Italy, Corsica, Spain
Exclusive Savings
Inside
$1,704
Oceanview
$1,853
Balcony
$2,150
Suite
$4,159
From (Per Person)
A$1,704
Per Person
Cruise
 (1)

4 Days (3 Nights) Rome to Barcelona
Departure: 04 May 2027
Visits: Italy, Spain
Just Cruise Fare
Exclusive Savings
Inside
$652
Oceanview
$711
Balcony
$889
Suite
$1,039
From (Per Person)
A$652
Per Person
Cruise
 (3)

19 Days (18 Nights) Trieste to Barcelona
Operator: Holland America
Ship: Oosterdam
Departure: 10 November 2027
Visits: Italy, Croatia, Greece, Turkey, Malta, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,539
Suite
-
From (Per Person)
A$8,539
Per Person
Cruise
 (9)

11 Days (10 Nights) Rome to Barcelona
Operator: Azamara
Departure: 17 July 2027
Visits: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$5,499
Oceanview
$5,842
Balcony
$7,097
Suite
$10,546
From (Per Person)
A$5,499
Save 90
Per Person
Cruise
 (1)

9 Days (8 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora II
Departures: Jul 2028 to Sep 2028
Visits: Italy, France, Corsica, Spain
Exclusive Savings
Suite
$6,169
From (Per Person)
A$6,169
Save 135
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Departures: Jun 2027 to Oct 2027
Visits: Italy, Sicily, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$1,137
Oceanview
$3,075
Balcony
$1,510
Suite
$1,600
From (Per Person)
A$1,137
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Operator: Oceania
Departure: 26 September 2027
Visits: Italy, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$2,954
Oceanview
$3,507
Balcony
$5,524
Suite
$6,708
From (Per Person)
A$2,954
Save 2,056
Per Person
Cruise
 (2)

11 Days (10 Nights) Florence to Malaga
Operator: Ponant
Ship: Le Boreal
Departure: 03 October 2027
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Oceanview
$9,402
Balcony
$9,877
Suite
$17,977
From (Per Person)
A$9,402
Save 248
Per Person
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Operator: Cunard
Departure: 14 July 2028
Visits: Italy, Spain, France, Corsica +5 more, Malta, Montenegro, Croatia, Greece, Sicily
Exclusive Savings
Inside
$4,907
Oceanview
$5,422
Balcony
$6,243
Suite
$10,995
From (Per Person)
A$4,907
Per Person
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Operator: Cunard
Departure: 28 July 2028
Visits: Italy, Croatia, Greece, Sicily, Spain
Exclusive Savings
Inside
$2,001
Oceanview
$2,150
Balcony
$2,447
Suite
$4,674
From (Per Person)
A$2,001
Per Person
Cruise
 (3)

22 Days (21 Nights) Trieste to Barcelona
Operator: Holland America
Ship: Oosterdam
Departure: 15 May 2027
Visits: Italy, Croatia, Montenegro, Greece +6 more, Sicily, Spain, Morocco, Sardinia, Corsica, France
Exclusive Savings
Inside
$5,830
Oceanview
$6,305
Balcony
$8,661
Suite
-
From (Per Person)
A$5,830
Per Person
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Operator: Cunard
Departure: 24 September 2027
Visits: Italy, France, Corsica, Spain
Exclusive Savings
Inside
$1,486
Oceanview
$1,704
Balcony
$1,853
Suite
$3,714
From (Per Person)
A$1,486
Per Person
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Operator: Celebrity Cruises
Departure: 06 July 2027
Visits: Italy, France, Spain
Exclusive Savings
Inside
$1,831
Oceanview
$2,023
Balcony
$2,287
Suite
$6,620
From (Per Person)
A$1,831
Save 1,372
Per Person
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Operator: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visits: Italy, Sicily, Tunisia, Algeria, Spain
Exclusive Savings
Suite
$6,527
From (Per Person)
A$6,527
Save 133
Per Person
Cruise
 (8)

15 Days (14 Nights) Rome to Barcelona
Operator: Princess
Ship: Sun Princess
Departures: May 2027 to Aug 2027
Visits: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Sanctuary Collection
Exclusive Savings
Inside
$3,334
Oceanview
$3,967
Balcony
$4,858
Suite
$5,710
From (Per Person)
A$3,334
Per Person
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Operator: Cunard
Departure: 16 June 2028
Visits: Italy, Croatia, Greece, Sicily, Spain
Exclusive Savings
Inside
$1,932
Oceanview
$2,150
Balcony
$2,486
Suite
$4,674
From (Per Person)
A$1,932
Per Person
Cruise
 (1)

10 Days (9 Nights) Bologna to Barcelona
Departures: Jul 2028 to Sep 2028
Visits: Italy, Croatia, Montenegro, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$3,727
Oceanview
$4,546
Balcony
$5,588
Suite
$7,077
From (Per Person)
A$3,727
Per Person
Results: 1-30 of 193

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