Cruises from Italy to Spain

Are you looking for a cruise from Italy to Spain? October is the most popular month to cruise between Italy and Spain and there are 147 departures available from fourteen of the world's leading cruise lines.
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34 Days
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89 Cruises (147 Cruise Departures)
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Oceania Cruises
Departure: 26 October 2024
Countries Visited: Italy, Croatia, Montenegro, Greece (+4 more), Sicily, Monaco, France, Spain
Early Booking Savings + OLife Choice
Inside
$4,130
Oceanview
$5,270
Balcony
$6,250
Suite
$8,810
Save 3,100
From 4,130
Cruise

10 Days (9 Nights) Rome to Barcelona
Departure: 16 April 2025
Countries Visited: Italy, France, Spain
Inside
$2,718
Oceanview
$3,343
Balcony
$3,656
Suite
$3,996
From 2,718
Cruise

23 Days (22 Nights) Venice to Barcelona
Cruise Line: Oceania Cruises
Departure: 27 October 2023
Countries Visited: Italy, Croatia, Montenegro, Greece (+5 more), Sicily, France, Spain, Gibraltar, Morocco
Early Booking Savings + OLife Choice
Inside
$7,970
Oceanview
$8,420
Balcony
$12,510
Suite
$17,500
Save 5,500
From 7,970
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Departure: 31 October 2024
Countries Visited: Italy, Monaco, France, Spain
Solo Cruise Deals
Inside
$3,134
Oceanview
$3,644
Balcony
$4,494
Suite
$6,017
From 3,134
Cruise

10 Days (9 Nights) Rome to Malaga
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 13 October 2023
Countries Visited: Italy, Spain, Morocco
Inside
-
Oceanview
-
Balcony
$1,629
Suite
-
From 1,629
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Oceania Cruises
Departure: 14 April 2023
Countries Visited: Italy, Croatia, Montenegro, Greece (+3 more), Sicily, France, Spain
Early Booking Savings + OLife Choice
Inside
$4,310
Oceanview
-
Balcony
-
Suite
-
Save 3,400
From 4,310
Cruise

13 Days (12 Nights) Venice to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 September 2023
Countries Visited: Italy, Croatia, Albania, Greece (+2 more), France, Spain
Have It All Offer
Inside
$3,539
Oceanview
$3,839
Balcony
$4,639
Suite
$5,939
From 3,539
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Scenic
Departure: 21 May 2023
Countries Visited: Italy, Corsica, France, Monaco (+1 more), Spain
Earlybird Saving + Early Payment Discount
Inside
-
Oceanview
-
Balcony
$10,923
Suite
-
Save 1,287
From 10,923
Cruise

21 Days (20 Nights) Venice to Barcelona
Cruise Line: Seabourn
Ship: Quest
Departure: 28 June 2023
Countries Visited: Italy, Croatia, Greece, Slovenia (+4 more), Montenegro, Malta, Spain, France
Save Now Cruise Later
Inside
-
Oceanview
$11,899
Balcony
$13,174
Suite
$24,224
From 11,899
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Departure: 15 July 2023
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Inside
$3,832
Oceanview
-
Balcony
$5,088
Suite
$7,402
From 3,832
Cruise

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Departures: Dec 2022 to Oct 2023
Countries Visited: Italy, France, Spain
Early Booking With Easy Drink Packages
Inside
$189
Oceanview
$249
Balcony
$329
Suite
$569
From 169
Cruise

13 Days (12 Nights) Venice to Barcelona
Cruise Line: Viking Cruises
Departures: Jul 2023 to Jul 2024
Countries Visited: Italy, Croatia, Greece, Monaco (+2 more), France, Spain
Earlybird SavingViking Latest Offers
Inside
-
Oceanview
-
Balcony
$7,835
Suite
$11,755
Save 1,583
From 7,835
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Departure: 29 July 2023
Countries Visited: Italy, Corsica, France, Spain
The Retreat Plus Bonus OffersSpring Sail Away
Inside
$2,104
Oceanview
$2,889
Balcony
$3,524
Suite
$5,675
From 2,104
Cruise

8 Days (7 Nights) Rome to Malaga
Cruise Line: Ponant
Ship: Le Lyrial
Departure: 01 October 2023
Countries Visited: Italy, Corsica, Spain
Early Booking Bonus
Inside
-
Oceanview
$6,440
Balcony
$6,980
Suite
$16,180
From 6,440
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Departure: 25 August 2023
Countries Visited: Italy, Sardinia, Corsica, Monaco (+2 more), France, Spain
Early Booking Savings + OLife Choice
Inside
$3,780
Oceanview
$4,000
Balcony
$5,440
Suite
$7,820
Save 3,400
From 3,780
Cruise

12 Days (11 Nights) Rome to Bilbao
Departure: 27 August 2023
Countries Visited: Italy, France, Spain, Portugal
Inside
$2,786
Oceanview
$3,177
Balcony
$4,896
Suite
$5,477
From 2,786
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Azamara Cruises
Departure: 30 May 2024
Countries Visited: Italy, Slovenia, Croatia, Montenegro (+2 more), Monaco, Spain
Solo Cruise Deals
Inside
$4,224
Oceanview
$4,904
Balcony
$5,814
Suite
$8,660
From 4,224
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Regent Seven Seas
Departure: 24 August 2023
Countries Visited: Italy, Croatia, Sicily, Monaco (+2 more), France, Spain
Gift Of Travel OfferEarly Booking Savings
Inside
-
Oceanview
-
Balcony
$13,215
Suite
$15,045
Save 4,015
From 13,215
Cruise

8 Days (7 Nights) Venice to Barcelona
Cruise Line: Royal Caribbean
Departure: 24 July 2023
Countries Visited: Italy, Slovenia, France, Spain
Limited Time Sale
Inside
$1,410
Oceanview
$1,741
Balcony
$3,673
Suite
$4,770
From 1,410
Cruise

8 Days (7 Nights) Venice to Barcelona
Cruise Line: Royal Caribbean
Departure: 18 September 2023
Countries Visited: Italy, Slovenia, Sicily, France (+1 more), Spain
Limited Time SaleKids Sail Offer
Inside
$1,373
Oceanview
$1,594
Balcony
$3,692
Suite
$5,106
From 1,373
Cruise

7 Days (6 Nights) Rome to Tenerife
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 13 October 2023
Countries Visited: Italy, Spain, Morocco
Inside
$679
Oceanview
$919
Balcony
$1,099
Suite
$2,839
From 579
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Departure: 25 July 2023
Countries Visited: Italy, Malta, Monaco, France (+1 more), Spain
Early Booking Savings + OLife Choice
Inside
-
Oceanview
-
Balcony
$7,570
Suite
-
Save 3,100
From 7,570
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Departures: May 2023 to Sep 2023
Countries Visited: Italy, Greece, Malta, Spain
The Retreat Plus Bonus OffersSpring Sail Away
Inside
$2,750
Oceanview
$3,373
Balcony
$3,452
Suite
$6,802
From 2,750
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Departure: 25 May 2023
Countries Visited: Italy, Monaco, France, Spain
Black Friday Sale
Inside
$3,888
Oceanview
$4,288
Balcony
-
Suite
$8,674
From 3,888
Cruise

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 13 October 2023
Countries Visited: Italy, Spain
Inside
$189
Oceanview
$289
Balcony
$399
Suite
$719
From 189
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Sojourn
Departures: Aug 2023 to Sep 2023
Countries Visited: Italy, Sardinia, Corsica, Monaco (+4 more), France, Spain, Gibraltar, Morocco
Save Now Cruise Later
Inside
-
Oceanview
$11,899
Balcony
$14,619
Suite
$24,224
From 11,899
Cruise

8 Days (7 Nights) Venice to Barcelona
Cruise Line: Royal Caribbean
Departure: 21 August 2023
Countries Visited: Italy, Slovenia, Sicily, France (+1 more), Spain
Limited Time Sale
Inside
$1,311
Oceanview
$1,656
Balcony
$3,671
Suite
$4,782
From 1,311
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Departures: Dec 2022 to Sep 2024
Countries Visited: Italy, Monaco, France, Spain
Earlybird SavingViking Latest Offers
Inside
-
Oceanview
-
Balcony
$2,935
Suite
$5,875
Save 1,730
From 2,935
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Departures: May 2023 to Sep 2023
Countries Visited: Italy, Corsica, France, Spain
The Retreat Plus Bonus OffersSpring Sail Away
Inside
$2,004
Oceanview
$2,643
Balcony
$3,283
Suite
$5,330
From 2,004
Cruise

13 Days (12 Nights) Rome to Barcelona
Cruise Line: Silversea
Departure: 16 May 2024
Countries Visited: Italy, Monaco, Spain, Malta
Door-To-Door All⁠ ⁠Inclusive
Inside
-
Oceanview
$13,500
Balcony
$16,700
Suite
$14,700
From 13,500
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