Cruises from Italy to Spain

Are you looking for a cruise from Italy to Spain? October is the most popular month to cruise between Italy and Spain and there are 204 departures available from fifteen of the world's leading cruise lines.
Filter Results
Departures
Show More...
Duration
3 Days
34 Days
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$100pp
$38,380pp
Countries
Show More...
Filter Results
118 Cruises (204 Cruise Departures)
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Regent Seven Seas
Departure: 24 August 2023
Countries Visited: Italy, Croatia, Sicily, Monaco (+2 more), France, Spain
Mutiple Deals Available
Inside
-
Oceanview
-
Balcony
$9,258
Suite
$9,618
From 9,258
Cruise

29 Days (28 Nights) Rome to Barcelona
Cruise Line: Cunard
Departure: 16 September 2024
Countries Visited: Italy, Greece, Montenegro, Croatia (+3 more), Malta, Spain, Turkey
Inside
$6,543
Oceanview
$7,137
Balcony
$8,226
Suite
$16,146
From 6,543
Cruise

11 Days (10 Nights) Rome to Barcelona
Departure: 26 April 2024
Countries Visited: Italy, France, Spain
Inside
$2,585
Oceanview
$3,173
Balcony
$4,203
Suite
$5,086
From 2,585
Cruise

19 Days (18 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 01 September 2024
Countries Visited: Italy, Sicily, Malta, Greece (+5 more), Turkey, Albania, Corsica, France, Spain
Have It All Early Booking Bonus Offer
Inside
$5,723
Oceanview
$6,218
Balcony
$7,406
Suite
$9,980
From 5,723
Cruise

10 Days (9 Nights) Rome to Barcelona
Departure: 16 April 2025
Countries Visited: Italy, France, Spain
Inside
$2,649
Oceanview
$3,238
Balcony
$3,532
Suite
$3,826
From 2,649
Cruise

23 Days (22 Nights) Venice to Barcelona
Cruise Line: Oceania Cruises
Departure: 27 October 2023
Countries Visited: Italy, Croatia, Montenegro, Greece (+5 more), Sicily, France, Spain, Gibraltar, Morocco
Early Booking Savings
Inside
-
Oceanview
$8,598
Balcony
$13,093
Suite
$18,251
From 8,598
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Departure: 31 October 2024
Countries Visited: Italy, Monaco, France, Spain
Solo Cruise Deals
Inside
$3,107
Oceanview
$3,611
Balcony
$4,453
Suite
$5,961
From 3,107
Cruise

10 Days (9 Nights) Rome to Malaga
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 13 October 2023
Countries Visited: Italy, Spain, Morocco
Limited Time Sale
Inside
$981
Oceanview
$1,328
Balcony
$1,664
Suite
$2,852
From 981
Cruise

13 Days (12 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 27 December 2023
Countries Visited: Italy, Sicily, Greece, Cyprus (+3 more), Israel, France, Spain
Inside
$1,516
Oceanview
$1,981
Balcony
$2,466
Suite
$3,347
From 1,516
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Sojourn
Departures: Aug 2023 to Sep 2023
Countries Visited: Italy, Sardinia, Corsica, Monaco (+4 more), France, Spain, Gibraltar, Morocco
Earlybird Saving
Inside
-
Oceanview
$14,671
Balcony
$17,839
Suite
$29,026
From 14,671
Cruise

13 Days (12 Nights) Venice to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 September 2023
Countries Visited: Italy, Croatia, Albania, Greece (+2 more), France, Spain
Have It All Offer
Inside
$3,511
Oceanview
$3,808
Balcony
$4,600
Suite
$5,887
From 3,511
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Scenic
Departure: 21 May 2023
Countries Visited: Italy, Corsica, France, Monaco (+1 more), Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,719
Suite
-
Save 251
From 12,719
Cruise

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Departure: 23 September 2024
Countries Visited: Italy, Croatia, Malta, Spain
Inside
$1,882
Oceanview
$2,179
Balcony
$2,377
Suite
$4,753
From 1,882
Cruise

21 Days (20 Nights) Venice to Barcelona
Cruise Line: Seabourn
Ship: Quest
Departure: 28 June 2023
Countries Visited: Italy, Croatia, Greece, Slovenia (+4 more), Montenegro, Malta, Spain, France
Earlybird Saving
Inside
-
Oceanview
$14,275
Balcony
$15,760
Suite
$28,630
From 14,275
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Departures: Jun 2024 to Sep 2024
Countries Visited: Italy, France, Spain
Inside
$1,882
Oceanview
$2,179
Balcony
$2,377
Suite
$4,753
From 1,882
Cruise

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Departures: May 2023 to Nov 2023
Countries Visited: Italy, France, Spain
Limited Time Sale
Inside
$158
Oceanview
$217
Balcony
$306
Suite
$455
From 148
Cruise

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Departure: 11 June 2023
Countries Visited: Italy, France, Spain
Limited Time Sale
Inside
$292
Oceanview
$361
Balcony
$480
Suite
$936
From 292
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 22 July 2024
Countries Visited: Italy, Malta, Tunisia, France (+3 more), Spain, Gibraltar, Morocco
Earlybird Saving
Inside
-
Oceanview
-
Balcony
$13,878
Suite
$28,233
From 13,878
Cruise

5 Days (4 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Departure: 09 May 2023
Countries Visited: Italy, Spain
Inside
-
Oceanview
$565
Balcony
$693
Suite
$1,149
From 565
Cruise
 (1)

13 Days (12 Nights) Venice to Barcelona
Cruise Line: Viking Cruises
Departures: Jul 2023 to Sep 2025
Countries Visited: Italy, Croatia, Greece, Monaco (+2 more), France, Spain
Earlybird Saving
Inside
-
Oceanview
-
Balcony
$7,717
Suite
$11,677
Save 476
From 7,639
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 19 April 2023
Countries Visited: Italy, Spain
Inside
-
Oceanview
-
Balcony
$589
Suite
-
From 589
Cruise

8 Days (7 Nights) Rome to Malaga
Cruise Line: Ponant
Ship: Le Lyrial
Departure: 01 October 2023
Countries Visited: Italy, Corsica, Spain
Early Booking Bonus
Inside
-
Oceanview
$6,747
Balcony
$7,311
Suite
$12,548
From 6,747
Cruise
 (1)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Departure: 25 August 2023
Countries Visited: Italy, Sardinia, Corsica, Monaco (+2 more), France, Spain
Early Booking Savings
Inside
$3,930
Oceanview
$4,147
Balcony
$5,731
Suite
-
From 3,930
Cruise

12 Days (11 Nights) Rome to Bilbao
Departure: 27 August 2023
Countries Visited: Italy, France, Spain, Portugal
Inside
$2,107
Oceanview
$2,548
Balcony
$3,652
Suite
$4,094
From 2,107
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Azamara Cruises
Departure: 30 May 2024
Countries Visited: Italy, Slovenia, Croatia, Montenegro (+2 more), Monaco, Spain
Solo Cruise Deals
Inside
$4,186
Oceanview
$4,859
Balcony
$5,760
Suite
$8,577
From 4,186
Cruise

8 Days (7 Nights) Venice to Barcelona
Cruise Line: Royal Caribbean
Departure: 24 July 2023
Countries Visited: Italy, Slovenia, France, Spain
Limited Time SaleUp to 30% Off All Guests.
Inside
$1,521
Oceanview
$1,787
Balcony
$3,748
Suite
$5,169
From 1,521
Cruise

8 Days (7 Nights) Venice to Barcelona
Cruise Line: Royal Caribbean
Departure: 18 September 2023
Countries Visited: Italy, Slovenia, Sicily, France (+1 more), Spain
Limited Time SaleUp to 30% Off All Guests.
Inside
$1,262
Oceanview
$1,405
Balcony
$3,864
Suite
$5,579
From 1,262
Cruise

7 Days (6 Nights) Rome to Tenerife
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 13 October 2023
Countries Visited: Italy, Spain, Morocco
Limited Time Sale
Inside
-
Oceanview
-
Balcony
$1,332
Suite
$2,402
From 1,332
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Pursuit
Departure: 20 August 2023
Countries Visited: Italy, France, Spain
Earlybird Saving
Inside
-
Oceanview
-
Balcony
$5,751
Suite
$8,424
From 5,751
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 30 October 2024
Countries Visited: Italy, Sardinia, Corsica, Monaco (+2 more), France, Spain
Earlybird Saving
Inside
-
Oceanview
-
Balcony
$7,929
Suite
$15,453
From 7,929
Results: 1-30 of 118

No Results found. Try changing your search filters.