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Spain Cruises Starting In April 2027 and 2028

If you're looking at joining a cruise to Spain in April 2027 or 2028, we have 231 unique cruise itineraries and 2,436 departures available, operated by nineteen of the world's leading cruise lines departing in April.
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231 Cruises (2,436 Cruise Departures)
5 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Lanzarote to Lanzarote
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2027 to Mar 2028
Visit: Spain
Inside
$510
Oceanview
$568
Balcony
$626
Suite
$1,641
From
US$510
Per Person
View Trip
7 Day Sailing the Canary Islands with G Adventures
Cruise

7 Days (6 Nights) San Miguel de Abona to San Miguel de Abona
Operated By: G Adventures
Departures: Oct 2026 to Apr 2028
Visit: Spain
From
US$1,199
Per Person
View Trip
9 Day Barcelona to Barcelona with Silversea
Cruise

9 Days (8 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 April 2027
Visit: Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,100
Suite
$10,200
From
US$6,100
Save 2,500
Per Person
View Trip
5 Day A Journey Through Riviera Elegance & Coastal Splendour with Explora Journeys
Cruise
 (1)

5 Days (4 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,760
From
US$4,760
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Inside
-
Oceanview
-
Balcony
$495
Suite
$955
From
US$495
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Visit: Italy, Spain
Inside
$139
Oceanview
$211
Balcony
$291
Suite
$631
From
US$139
Per Person
View Trip
8 Day Spain Intensive Cruise: Malaga, Valencia & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Malaga to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 April 2027
Visit: Spain, Gibraltar
Azamara Always Included
Inside
$2,179
Oceanview
$2,489
Balcony
$3,279
Suite
$5,259
From
US$2,179
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Inside
$339
Oceanview
$429
Balcony
$519
Suite
$1,259
From
US$339
Per Person
View Trip
8 Day Gastronomic Journey Through Iberian Coasts with Ponant
Cruise
 (2)

8 Days (7 Nights) Lisbon to Barcelona
Cruise Line: Ponant
Ship: Le Boreal
Departure: 25 April 2027
Visit: Portugal, Spain
Inside
-
Oceanview
$6,490
Balcony
$6,850
Suite
$11,470
From
US$6,490
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain
Inside
-
Oceanview
$1,041
Balcony
$1,421
Suite
-
From
US$1,041
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Splendida
Departures: Apr 2027 to Apr 2027
Visit: Brazil, Spain
Inside
$850
Oceanview
$960
Balcony
$1,340
Suite
-
From
US$850
Per Person
View Trip
11 Day Ocean Voyage: Fort de France - Santa Cruz de Tenerife with Ponant
Cruise
 (2)

11 Days (10 Nights) Fort-de-France to Santa Cruz de Tenerife
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 03 April 2027
Visit: Martinique, Spain
Inside
-
Oceanview
-
Balcony
$3,840
Suite
$5,670
From
US$3,840
Per Person
View Trip
10 Day Wellness Retreat - Barbados to Spain with Scenic
New ReleaseCruise

10 Days (9 Nights) Bridgetown to Santa Cruz de Tenerife
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 24 April 2026
Visit: Barbados, Spain
Inside
-
Oceanview
-
Balcony
$6,595
Suite
$9,295
From
US$6,595
Per Person
View Trip
11 Day Volcanic Islands and Historic Cities of the North Atlantic with Ponant
Cruise

11 Days (10 Nights) Las Palmas de Gran Canaria to Lisbon
Cruise Line: Ponant
Ship: L'Austral
Departure: 28 April 2026
Visit: Spain, Portugal
Inside
-
Oceanview
$5,840
Balcony
$6,280
Suite
$10,040
From
US$5,840
Per Person
View Trip
11 Day Volcanic Islands and Historic Cities of the North Atlantic with Ponant
Cruise

11 Days (10 Nights) Las Palmas de Gran Canaria to Lisbon
Cruise Line: Ponant
Ship: L'Austral
Departure: 28 April 2026
Visit: Spain, Portugal
Inside
-
Oceanview
$5,840
Balcony
$6,280
Suite
$10,360
From
US$5,840
Per Person
View Trip
6 Day Palma De Mallorca to Nice with Silversea
Cruise

6 Days (5 Nights) Palma de Mallorca to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 27 April 2026
Visit: Spain, France
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$1,950
Balcony
$2,450
Suite
$6,700
From
US$1,950
Per Person
View Trip
13 Day Wellness Retreat: Rio to Santa Cruz de Tenerife with Scenic
New ReleaseCruise

13 Days (12 Nights) Rio de Janeiro to Tenerife
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 06 April 2028
Visit: Brazil, Spain
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,966
Suite
$10,500
From
US$6,966
Save 1,879
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Italy, Spain, France
Inside
$580
Oceanview
$716
Balcony
$1,036
Suite
$1,316
From
US$580
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Spain, France, Italy
Inside
$616
Oceanview
$751
Balcony
$1,088
Suite
$1,328
From
US$616
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: May 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,499
From
US$2,599
Save 800
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: France, Italy, Spain
Inside
$1,226
Oceanview
$1,436
Balcony
$1,556
Suite
$2,286
From
US$1,226
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Spain, France, Italy
Inside
$579
Oceanview
$679
Balcony
$999
Suite
$1,279
From
US$579
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC World Europa
Departures: Oct 2026 to Oct 2027
Visit: Spain, France, Italy
Inside
$1,224
Oceanview
$1,466
Balcony
$1,474
Suite
$2,224
From
US$1,224
Per Person
View Trip
8 Day Portugal, Spain & Morocco Cruise: Lisbon, Seville & Tangier with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Lisbon to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 April 2027
Visit: Portugal, Spain, Morocco
Azamara Always Included
Inside
$2,279
Oceanview
$2,589
Balcony
$3,359
Suite
$5,229
From
US$2,279
Per Person
View Trip
13 Day Springtime Splendor with Oceania Cruises
Cruise
 (3)

13 Days (12 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 28 April 2027
Visit: Spain, Morocco, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,799
Oceanview
$5,199
Balcony
$6,099
Suite
$8,449
From
US$3,799
Save 3,799
Per Person
View Trip
11 Day Atlantic Odyssey from the Canary Islands to the Shores of Morocco with Ponant
Cruise
 (2)

11 Days (10 Nights) Las Palmas de Gran Canaria to Casablanca
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 April 2027
Visit: Spain, Portugal, Morocco
Inside
-
Oceanview
-
Balcony
$6,400
Suite
$8,950
From
US$6,400
Per Person
View Trip
8 Day Iberian Peninsula & Sicily with Ponant
Cruise
 (1)

8 Days (7 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 28 April 2026
Visit: Spain, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$6,260
Suite
$11,700
From
US$6,260
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC World Europa
Departures: Oct 2026 to Oct 2027
Visit: Spain, France, Italy
Inside
$1,130
Oceanview
$1,270
Balcony
$1,430
Suite
$2,200
From
US$1,130
Per Person
View Trip
9 Day Canary Islands with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Santa Cruz De Tenerife to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 04 April 2027
Visit: Spain, Morocco, Italy
Inside
$869
Oceanview
$1,088
Balcony
$1,091
Suite
$1,651
From
US$869
Per Person
View Trip
13 Day Canary Islands with Princess
Cruise
 (2)

13 Days (12 Nights) London to London
Cruise Line: Princess
Ship: Sky Princess
Departure: 12 April 2027
Visit: England, Spain, Portugal
Princess Standard
Inside
$2,009
Oceanview
-
Balcony
$2,460
Suite
$2,899
From
US$2,009
Per Person
View Trip
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