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Cruises from Spain to Italy

Are you looking for a cruise from Spain to Italy? August is the most popular month to cruise between Spain and Italy and there are 192 departures available from sixteen of the world's leading cruise lines.
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117 Cruises (192 Cruise Departures)
8 Day Italy And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Countries Visited: Spain, Sardinia, Sicily, Italy
INSIDE
$1,684
OCEANVIEW
$1,882
BALCONY
$2,080
SUITE
$4,654
From 1,684
View Trip
12 Day Barcelona to Rome with Silversea
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 26 April 2025
Countries Visited: Spain, France, Italy, Monaco
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,652
From 14,652
View Trip
6 Day France & Italy Cruise with Royal Caribbean
Cruise

6 Days (5 Nights) Barcelona to Ravenna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 12 May 2025
Countries Visited: Spain, Corsica, Italy, Sicily
Exclusive Deal
INSIDE
$1,371
OCEANVIEW
$1,816
BALCONY
$1,996
SUITE
$3,371
Save 535
From 1,202
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise

15 Days (14 Nights) Barcelona to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+5 more), Viking Saturn, Viking Sky, Viking Star, Viking Venus, Viking Vesta
Departures: Jul 2024 to Jul 2026
Countries Visited: Spain, France, Monaco, Italy (+2 more), Sicily, Croatia
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,697
SUITE
$14,350
Save 1,957
From 9,697
View Trip
18 Day Canary Islands And Madeira with MSC Cruises
Cruise

18 Days (17 Nights) Las Palmas de Gran Canaria to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 17 March 2025
Countries Visited: Spain, Portugal, Morocco, Sicily (+3 more), Greece, Italy, Croatia
Save And Sail Offer
INSIDE
$3,191
OCEANVIEW
$4,032
BALCONY
$6,280
SUITE
$9,715
From 3,191
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise

3 Days (2 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 08 May 2024
Countries Visited: Spain, Italy
Best Deal Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$456
SUITE
$704
From 456
View Trip
11 Day Europe - Mediterranean with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Barcelona to Venice
Ship: Norwegian Dawn
Departure: 07 October 2024
Countries Visited: Spain, France, Italy, Sicily (+4 more), Greece, Montenegro, Slovenia, Croatia
Free At Sea Offer
INSIDE
$3,356
OCEANVIEW
$3,675
BALCONY
$4,769
SUITE
$5,148
From 3,356
View Trip
8 Day A Journey From Tarragona To Rome with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 23 September 2024
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,311
SUITE
$7,311
From 6,311
View Trip
13 Day Mediterranean Odyssey with Viking Cruises
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+5 more), Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela
Departures: Jul 2024 to Aug 2026
Countries Visited: Spain, France, Italy, Greece (+1 more), Croatia
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$14,845
Save 1,204
From 9,895
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
INSIDE
$6,246
OCEANVIEW
$6,741
BALCONY
$7,731
SUITE
$17,829
From 6,246
View Trip
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia (+2 more), Montenegro, Greece
INSIDE
$2,766
OCEANVIEW
$3,212
BALCONY
$3,657
SUITE
$7,667
From 2,766
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 July 2025
Countries Visited: Spain, Corsica, France, Italy (+2 more), Sardinia, Sicily
INSIDE
$2,855
OCEANVIEW
$3,033
BALCONY
$3,568
SUITE
$7,399
From 2,855
View Trip
9 Day Mediterranean Marvels & Matches: Monte Carlo Masters with Seabourn
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Venture
Departure: 05 April 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,403
SUITE
$25,055
From 10,403
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Valencia to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 27 March 2025
Countries Visited: Spain, Sicily, Greece, Italy (+1 more), Croatia
Early Booking Offer
INSIDE
$1,405
OCEANVIEW
$1,751
BALCONY
$2,682
SUITE
$4,088
From 1,405
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise

8 Days (7 Nights) Barcelona to Naples
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, Gibraltar, France, Italy
INSIDE
$1,667
OCEANVIEW
$2,073
BALCONY
$2,350
SUITE
$2,825
From 1,667
View Trip
13 Day Best Of The Med Voyage with Azamara Cruises
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 13 July 2024
Countries Visited: Spain, France, Monaco, Italy (+3 more), Montenegro, Croatia, Slovenia
INSIDE
$3,424
OCEANVIEW
$4,220
BALCONY
$5,079
SUITE
$7,191
From 3,423
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Malaga to Genoa
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 22 April 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$2,431
From 2,431
View Trip
10 Day Timeless Spain with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 July 2024
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,197
SUITE
-
Save 3,483
From 14,197
View Trip
11 Day Flavors Of The Mediterranean with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 18 September 2024
Countries Visited: Spain, France, Italy
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$7,564
BALCONY
$7,876
SUITE
$12,193
Save 8,486
From 7,564
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Splendida
Departures: May 2024 to Nov 2024
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$601
BALCONY
$691
SUITE
$965
From 601
View Trip
11 Day Italian Riviera & France with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 08 June 2024
Countries Visited: Spain, Corsica, Italy, France (+3 more), Sardinia, Malta, Sicily
Exclusive DealExclusive Offer
INSIDE
$2,634
OCEANVIEW
$3,154
BALCONY
$3,931
SUITE
$10,537
Save 3,451
From 2,634
View Trip
8 Day Etruscan Waterways with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 21 April 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
$3,872
OCEANVIEW
$4,714
BALCONY
$5,248
SUITE
$7,298
Save 2,028
From 3,872
View Trip
8 Day Italy, Greece & Croatia with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Ravenna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 11 May 2024
Countries Visited: Spain, Italy, Sicily, Greece (+2 more), Montenegro, Croatia
Exclusive Deal
INSIDE
$2,387
OCEANVIEW
$3,100
BALCONY
$4,214
SUITE
$4,823
Save 768
From 1,637
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Alicante to Rome
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 26 November 2024
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$614
BALCONY
$742
SUITE
$1,445
From 614
View Trip
25 Day Mediterranean Autumn with Oceania Cruises
Cruise

25 Days (24 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 02 October 2024
Countries Visited: Spain, France, Corsica, Italy (+5 more), Sicily, Greece, Montenegro, Croatia, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,015
SUITE
$22,499
Save 2,135
From 16,015
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sicily
INSIDE
$2,726
OCEANVIEW
$2,974
BALCONY
$3,370
SUITE
$7,231
From 2,726
View Trip
8 Day Spain, France & Italy Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 06 July 2024
Countries Visited: Spain, France, Italy
Exclusive DealExclusive Offer
INSIDE
$2,195
OCEANVIEW
$2,558
BALCONY
$3,189
SUITE
$7,122
Save 2,710
From 2,195
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 July 2025
Countries Visited: Spain, Corsica, France, Italy
INSIDE
$1,516
OCEANVIEW
$1,645
BALCONY
$1,912
SUITE
$3,833
From 1,516
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Sep 2024 to Oct 2024
Countries Visited: Spain, France, Corsica, Italy (+2 more), Malta, Sicily
Exclusive DealExclusive Offer
INSIDE
$2,431
OCEANVIEW
$3,729
BALCONY
$3,786
SUITE
$9,452
Save 3,618
From 2,431
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 September 2025
Countries Visited: Spain, Sardinia, Corsica, Sicily (+1 more), Italy
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
Results: 61-90 of 117

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