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Cruises from Lisbon to Rome

Are you looking for a cruise from Lisbon to Rome? September is the most popular month to cruise between Lisbon and Rome and there are 38 departures available from seven of the world's leading cruise lines.
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9 Days
23 Days
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$47,398pp
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21 Cruises (38 Cruise Departures)
12 Day Western Mediterranean: Spain, Malta & Italy with Holland America
Cruise
 (2)

12 Days (11 Nights) Lisbon to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 03 June 2026
Visit: Portugal, Spain, Morocco, Malta, Sicily, Italy
Fare Saver
Inside
$1,999
Oceanview
$2,189
Balcony
$2,879
Suite
$3,577
From
US$1,999
Per Person
View Trip
15 Day Iberian Wanderlust & Sicilian Dream with Regent Seven Seas
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 27 September 2027
Visit: Portugal, Spain, Morocco, Tunisia (+4 more), Sicily, Malta, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,103
Suite
$12,475
From
US$11,103
Save 18,495
Per Person
View Trip
11 Day Lisbon to Rome with Silversea
Cruise

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 04 January 2026
Visit: Portugal, Morocco, Spain, France, Italy
All-Inclusive Fare
Inside
-
Oceanview
$6,500
Balcony
$7,500
Suite
-
From
US$6,500
Per Person
View Trip
19 Day Mediterranean & North Africa Voyage: Portugal, Morocco & Italy with Azamara Cruises
Cruise
 (8)

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 17 November 2026
Visit: Portugal, Morocco, Spain, Gibraltar, France, Italy
Azamara Always Included
Exclusive Savings
Inside
$4,259
Oceanview
$4,686
Balcony
$5,734
Suite
$8,993
From
US$4,259
Save 80
Per Person
View Trip
23 Day Spanish Summer with Regent Seven Seas
Cruise

23 Days (22 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 11 August 2027
Visit: Portugal, Spain, Morocco, France (+4 more), Monaco, Italy, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,391
Suite
$20,086
From
US$17,391
Save 30,007
Per Person
View Trip
19 Day Timeless Shores with Regent Seven Seas
Cruise

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 08 June 2027
Visit: Portugal, Spain, Morocco, Corsica, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,913
Suite
$16,354
From
US$15,913
Save 24,485
Per Person
View Trip
11 Day Lisbon to Rome with Silversea
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 14 June 2026
Visit: Portugal, Spain, France, Monaco, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,010
Suite
$14,300
From
US$9,010
Save 1,590
Per Person
View Trip
11 Day Portrait Of Iberia with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 24 July 2026
Visit: Portugal, Spain, Gibraltar, Corsica, Italy
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,746
Oceanview
$3,034
Balcony
$4,560
Suite
$6,209
From
US$2,746
Save 3,852
Per Person
View Trip
11 Day Charming Mediterranean with Emerald Cruises
Cruise
 (3)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 30 April 2027
Visit: Portugal, Spain, Sardinia, Corsica, Italy
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$7,968
Balcony
-
Suite
$10,975
From
US$7,968
Save 11,322
Per Person
View Trip
15 Day Sublime Spain with Regent Seven Seas
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 October 2027
Visit: Portugal, Spain, Morocco, France, Monaco, Italy, Corsica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,103
Suite
$12,475
From
US$11,103
Save 18,495
Per Person
View Trip
13 Day Iconic Cathedrals & Castles with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 17 July 2027
Visit: Portugal, Spain, France, Monaco, Italy
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$3,815
Oceanview
$4,155
Balcony
$6,434
Suite
$8,956
From
US$3,815
Save 3,983
Per Person
View Trip
15 Day Vibrant Cultural Tapestry with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 26 August 2027
Visit: Portugal, Spain, France, Sardinia, Tunisia, Sicily, Italy
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$4,110
Oceanview
$4,498
Balcony
$7,117
Suite
$10,124
From
US$4,110
Save 4,288
Per Person
View Trip
11 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 06 April 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,400
Suite
$10,115
From
US$8,400
Per Person
View Trip
10 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise

10 Days (9 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 06 September 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,020
Balcony
$7,560
Suite
$7,200
From
US$7,020
Save 780
Per Person
View Trip
11 Day Balearic Bliss with Oceania Cruises
Cruise

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 26 September 2027
Visit: Portugal, Spain, France, Italy
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,910
Suite
$6,432
From
US$3,910
Save 4,088
Per Person
View Trip
18 Day Lisbon To Liguria with Regent Seven Seas
Cruise

18 Days (17 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 08 May 2027
Visit: Portugal, Spain, Morocco, France (+4 more), Monaco, Italy, Sicily, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,219
Suite
$14,395
From
US$13,219
Save 20,679
Per Person
View Trip
9 Day Mediterranean Sunrise with Oceania Cruises
Cruise
 (3)

9 Days (8 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 03 March 2027
Visit: Portugal, Spain, France, Italy
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,399
Oceanview
$2,595
Balcony
$3,808
Suite
$5,263
From
US$2,399
Save 2,399
Per Person
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+7 more), Viking Libra, Viking Mira, Viking Neptune, Viking Saturn, Viking Sky, Viking Star, Viking Vela
Departures: Nov 2026 to Jun 2028
Visit: Portugal, Spain, Morocco, France, Monaco, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,598
Suite
$8,998
From
US$5,598
Save 100
Per Person
View Trip
15 Day Iberia & Italian Treasures with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 21 December 2026
Visit: Portugal, Spain, France, Italy, Corsica
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,994
Oceanview
$4,363
Balcony
$6,667
Suite
$9,247
From
US$3,994
Save 4,604
Per Person
View Trip
13 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise

13 Days (12 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 28 September 2027
Visit: Portugal, Spain, Gibraltar, Sardinia, Corsica, Italy
All-Inclusive Fare
Inside
-
Oceanview
$8,400
Balcony
$9,200
Suite
$19,000
From
US$8,400
Per Person
View Trip
15 Day Lisbon to Civitavecchia with Silversea
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 October 2026
Visit: Portugal, Spain, Gibraltar, Sardinia, Tunisia, Sicily, Italy
All-Inclusive Fare
Inside
-
Oceanview
$8,500
Balcony
$9,100
Suite
$16,000
From
US$8,500
Per Person
View Trip
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