Home > Cruises > Europe Cruises > Western Europe Cruises > Cruises from Portugal to Italy

Cruises from Portugal to Italy

Are you looking for a cruise from Portugal to Italy? September is the most popular month to cruise between Portugal and Italy and there are 64 departures available from ten of the world's leading cruise lines.
Filter Results
40 Cruises (64 Departures)
40 Cruises (64 Departures)
Departures
Show More...
Duration
6 Days
27 Days
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$700pp
$38,060pp
Countries
Show More...
Cruise
 (3)

27 Days (26 Nights) Lisbon to Trieste
Cruise Line: Oceania
Departure: 27 June 2028
Visits: Portugal, Spain, France, Sardinia +7 more, Tunisia, Sicily, Italy, Malta, Greece, Montenegro, Croatia
Your World Inclusions
Exclusive Savings
Inside
$11,003
Oceanview
$14,524
Balcony
$17,628
Suite
$24,806
From (Per Person)
A$11,003
Save 2,297
Per Person
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Oceania
Departure: 24 July 2026
Visits: Portugal, Spain, Gibraltar, Corsica, Italy
Your World Inclusions
Exclusive Savings
Oceanview
$2,861
Balcony
$3,690
Suite
$4,995
From (Per Person)
A$2,861
Save 4,949
Per Person
Cruise
 (1)

16 Days (15 Nights) Lisbon to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 21 December 2026
Visits: Portugal, Gibraltar, Spain, France, Italy
Exclusive Savings
Suite
$15,469
From (Per Person)
A$15,469
Save 316
Per Person
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 06 April 2027
Visits: Portugal, Spain, France, Italy
Exclusive Savings
Balcony
$9,408
Suite
$19,502
From (Per Person)
A$9,408
Save 6,592
Per Person
Cruise
 (3)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania
Departure: 27 June 2028
Visits: Portugal, Spain, France, Sardinia, Tunisia, Sicily, Italy
Your World Inclusions
Exclusive Savings
Inside
$6,252
Oceanview
$8,212
Balcony
$9,900
Suite
$14,100
From (Per Person)
A$6,252
Save 2,168
Per Person
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania
Departure: 21 December 2026
Visits: Portugal, Spain, France, Italy, Corsica
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$4,810
Balcony
$7,159
Suite
$9,658
From (Per Person)
A$4,810
Save 4,190
Per Person
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 23 February 2027
Visits: Portugal, Spain, Morocco, Sardinia, Sicily, Italy
Exclusive Savings
Suite
$8,452
From (Per Person)
A$8,452
Save 173
Per Person
Cruise
 (3)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Emerald Cruises
Departure: 30 April 2027
Visits: Portugal, Spain, Sardinia, Corsica, Italy
Exclusive Savings
Oceanview
-
Suite
$16,792
From (Per Person)
A$16,792
Save 2,803
Per Person
Cruise
 (8)

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Azamara
Departure: 17 November 2026
Visits: Portugal, Morocco, Spain, Gibraltar, France, Italy
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$9,346
Balcony
-
Suite
$14,844
From (Per Person)
A$9,346
Save 143
Per Person
Cruise
 (1)

9 Days (8 Nights) Lisbon to Rome
Cruise Line: Oceania
Departure: 03 March 2027
Visits: Portugal, Spain, France, Italy
Your World Inclusions
Exclusive Savings
Inside
$2,500
Oceanview
$2,449
Balcony
$3,591
Suite
$4,958
From (Per Person)
A$2,449
Save 3,371
Per Person
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania
Departure: 26 August 2027
Visits: Portugal, Spain, France, Sardinia, Tunisia, Sicily, Italy
Your World Inclusions
Exclusive Savings
Inside
$5,860
Oceanview
$6,413
Balcony
$10,700
Suite
$14,163
From (Per Person)
A$5,860
Save 2,120
Per Person
Cruise
 (1)

18 Days (17 Nights) Lisbon to Venice
Cruise Line: Oceania
Departure: 24 July 2026
Visits: Portugal, Spain, Gibraltar, Corsica +6 more, Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Your World Inclusions
Exclusive Savings
Balcony
$12,861
Suite
$27,809
From (Per Person)
A$12,861
Save 2,319
Per Person
Cruise
 (4)

22 Days (21 Nights) Lisbon to Rome
Cruise Line: Azamara
Departure: 25 March 2028
Visits: Portugal, Spain, Morocco, Gibraltar, France, Monaco, Italy
Azamara Always Included
Exclusive Savings
Inside
$7,553
Oceanview
$8,121
Balcony
$9,944
Suite
$13,864
From (Per Person)
A$7,553
Per Person
Cruise
 (2)

14 Days (13 Nights) Funchal to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 30 March 2027
Visits: Portugal, Spain, Morocco, Italy
Exclusive Savings
Inside
$2,224
Oceanview
$2,551
Balcony
$2,838
Suite
$4,650
From (Per Person)
A$2,224
Per Person
Cruise

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Oceania
Departure: 06 August 2028
Visits: Portugal, Spain, Gibraltar, Corsica, Sardinia, Italy
Your World Inclusions
Exclusive Savings
Balcony
$6,381
Suite
$10,232
From (Per Person)
A$6,381
Save 2,179
Per Person
Cruise

10 Days (9 Nights) Lisbon to Rome
Cruise Line: Silversea
Departure: 06 September 2027
Visits: Portugal, Spain, France, Italy
Exclusive Savings
Oceanview
$8,497
Balcony
$9,320
Suite
$9,085
From (Per Person)
A$8,497
Save 5,953
Per Person
Cruise

13 Days (12 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 28 September 2027
Visits: Portugal, Spain, Gibraltar, Sardinia, Corsica, Italy
Exclusive Savings
Oceanview
$12,083
Balcony
$13,847
Suite
$29,694
From (Per Person)
A$12,083
Save 1,617
Per Person
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 30 September 2027
Visits: Portugal, Spain, Sardinia, Italy, France, Morocco, Gibraltar
Exclusive Savings
Inside
$3,045
Oceanview
$3,471
Balcony
$4,956
Suite
$5,451
From (Per Person)
A$3,045
Per Person
Cruise

22 Days (21 Nights) Lisbon to Venice
Cruise Line: Viking
Departures: Feb 2027 to Jun 2028
Visits: Portugal, Spain, Morocco, France +4 more, Monaco, Italy, Sicily, Croatia
Exclusive Savings
Balcony
$15,724
Suite
$25,524
From (Per Person)
A$15,724
Save 1,711
Per Person
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Departure: 17 October 2027
Visits: Portugal, Spain, Morocco, France, Monaco, Italy, Corsica
Exclusive Savings
Balcony
$19,980
Suite
$23,303
From (Per Person)
A$19,980
Save 2,360
Per Person
Cruise

13 Days (12 Nights) Lisbon to Trieste
Cruise Line: Oceania
Departure: 25 September 2027
Visits: Portugal, Spain, France, Italy, Sicily, Greece
Your World Inclusions
Exclusive Savings
Balcony
$8,898
Suite
$12,982
From (Per Person)
A$8,898
Save 2,222
Per Person
Cruise

25 Days (24 Nights) Lisbon to Trieste
Cruise Line: Oceania
Departure: 27 December 2028
Visits: Portugal, Spain, Morocco, Sardinia +5 more, Italy, Sicily, Tunisia, Malta, Croatia
Your World Inclusions
Exclusive Savings
Balcony
$11,258
Suite
$19,377
From (Per Person)
A$11,258
Save 2,322
Per Person
Cruise

20 Days (19 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Departure: 17 March 2029
Visits: Portugal, Morocco, Spain, France +4 more, Italy, Sardinia, Malta, Sicily
Exclusive Savings
Balcony
$25,173
Suite
$28,535
From (Per Person)
A$25,173
Save 2,447
Per Person
Cruise

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Departure: 08 June 2027
Visits: Portugal, Spain, Morocco, Corsica, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$35,398
Suite
$35,683
From (Per Person)
A$35,398
Save 2,662
Per Person
Cruise

18 Days (17 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Departure: 08 May 2027
Visits: Portugal, Spain, Morocco, France +4 more, Monaco, Italy, Sicily, Sardinia
Exclusive Savings
Balcony
$31,715
Suite
$33,596
From (Per Person)
A$31,715
Save 2,585
Per Person
Cruise

11 Days (10 Nights) Lisbon to Genoa
Cruise Line: Seabourn
Departure: 08 April 2027
Visits: Portugal, Spain, France, Corsica, Italy
Exclusive Savings
Balcony
$7,464
Suite
$12,424
From (Per Person)
A$7,464
Save 138
Per Person
Cruise

23 Days (22 Nights) Lisbon to Trieste
Cruise Line: Oceania
Departure: 26 February 2029
Visits: Portugal, Spain, Gibraltar, Sardinia +9 more, Sicily, Tunisia, Malta, Greece, Turkey, Montenegro, Croatia, Slovenia, Italy
Your World Inclusions
Exclusive Savings
Balcony
$11,000
Suite
$18,576
From (Per Person)
A$11,000
Save 2,300
Per Person
Cruise

23 Days (22 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Departure: 11 August 2027
Visits: Portugal, Spain, Morocco, France +4 more, Monaco, Italy, Corsica, Sardinia
Exclusive Savings
Balcony
$32,109
Suite
$34,520
From (Per Person)
A$32,109
Save 2,581
Per Person
New ReleaseCruise

9 Days (8 Nights) Lisbon to Rome
Cruise Line: Crystal
Departure: 05 May 2028
Visits: Portugal, Spain, Corsica, Italy
Oceanview
$8,000
Balcony
$9,500
Suite
$9,790
From (Per Person)
A$8,000
Per Person
Cruise

17 Days (16 Nights) Lisbon to Rome
Cruise Line: Seabourn
Departure: 06 April 2028
Visits: Portugal, Spain, Morocco, France, Corsica, Sardinia, Italy
Exclusive Savings
Balcony
$14,586
Suite
$33,593
From (Per Person)
A$14,586
Save 263
Per Person
Results: 1-30 of 40

No trips found. Try adjusting the search filters.