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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 2,032 expeditions and cruises around South America travelling with the world's leading cruise lines.
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441 Cruises (2,032 Departures)
441 Cruises (2,032 Departures)
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141 Days
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22 Day Southern Fjords & Glaciers with Oceania Cruises Featured
Cruise
 (1)

22 Days (21 Nights) Valparaiso to Buenos Aires
Operator: Oceania
Ship: Oceania Insignia
Departure: 14 February 2027
Visits: Chile, Argentina, Antarctica, Falkland Islands
Your World Inclusions
Exclusive Savings
Inside
$11,134
Oceanview
$12,036
Suite
$28,313
From (Per Person)
A$11,134
Save 2,266
Per Person
View Trip
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Oct 2027
Interests: Coach, Cruise, Island Hopping, Wildlife
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$18,556
Save 446
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (2)

18 Days (17 Nights) Buenos Aires to Santiago
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Feb 2027 to Jan 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Balcony
$14,009
Suite
$22,339
From (Per Person)
A$14,009
Save 320
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Dec 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$7,014
Save 314
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,162
Save 2,162
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operator: Travelmarvel
Cruise Line: Holland America
Departure: 19 February 2028
Interests: Coach, Cruise
Visits: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Exclusive Savings
Oceanview
$21,143
Balcony
$23,250
From (Per Person)
A$21,143
Save 2,352
Per Person
View Trip
15 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with Globus
New ReleaseTour + Cruise
 (1)

15 Days Lima to Guayaquil
Operator: Globus
Departures: Jun 2027 to Nov 2028
Interests: Coach, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,639
Save 623
Per Person
View Trip
22 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Nazca Lines & the Amazon with Globus
New ReleaseTour + Cruise
 (1)

22 Days Lima to Quito
Operator: Globus
Departures: Feb 2028 to Nov 2028
Interests: Coach, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$20,807
Save 598
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Buenos Aires
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Jan 2027 to Feb 2029
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Balcony
$13,617
Suite
$22,339
From (Per Person)
A$13,617
Save 320
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Jan 2027 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$15,338
Save 493
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Nov 2027
Interests: Coach, Cruise, Island Hopping, Wildlife
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,127
Save 396
Per Person
View Trip
15 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

15 Days (14 Nights) Santiago to Buenos Aires
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 21 February 2028
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Inside
$3,598
Oceanview
$3,994
Balcony
$5,628
Suite
$7,360
From (Per Person)
A$3,598
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
$1,300
Oceanview
$1,340
Balcony
$1,468
Suite
$3,589
From (Per Person)
A$1,300
Per Person
View Trip
13 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 02 January 2029
Visits: Argentina, Uruguay, Chile
Exclusive Savings
Inside
$2,594
Oceanview
$2,897
Balcony
$3,034
Suite
$10,048
From (Per Person)
A$2,594
Save 1,516
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 22 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,315
Suite
$3,216
From (Per Person)
A$2,315
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departure: 26 January 2027
Visits: Brazil
Exclusive Savings
Inside
$765
Oceanview
$815
Balcony
$815
Suite
$1,023
From (Per Person)
A$765
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Valparaiso to Ushuaia
Operator: Azamara
Ship: Azamara Quest
Departure: 24 January 2028
Visits: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$8,292
Balcony
$11,202
Suite
$16,818
From (Per Person)
A$8,292
Save 147
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ship: MSC Splendida
Departures: Dec 2026 to Mar 2028
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,545
Oceanview
$1,743
Balcony
$1,882
Suite
$2,506
From (Per Person)
A$1,545
Per Person
View Trip
14 Day World Cruise: Panama Canal & South American Explorer with Seabourn
Cruise
 (1)

14 Days (13 Nights) Miami to Lima
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2029
Visits: USA, Colombia, Panama, Ecuador, Peru
Exclusive Savings
Oceanview
$11,492
Balcony
$14,628
Suite
$25,506
From (Per Person)
A$11,492
Save 207
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Holland America
Ship: Nieuw Amsterdam
Departures: Nov 2027 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Inside
$3,227
Oceanview
$3,505
Balcony
$4,732
Suite
$6,910
From (Per Person)
A$3,227
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 31 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$2,714
Oceanview
-
Balcony
$2,882
Suite
-
From (Per Person)
A$2,714
Per Person
View Trip
11 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise
 (1)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Operator: Silversea
Ship: Silver Nova
Departure: 11 February 2029
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Balcony
$12,054
Suite
$18,522
From (Per Person)
A$12,054
Save 1,996
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 08 March 2028
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,575
Oceanview
$1,783
Balcony
$2,179
Suite
$2,832
From (Per Person)
A$1,575
Per Person
View Trip
15 Day Brazil Intensive Cruise: Salvador, Natal & Belem with Azamara Cruises
Cruise
 (6)

15 Days (14 Nights) Rio de Janeiro to Bridgetown
Operator: Azamara
Ship: Azamara Quest
Departure: 28 February 2028
Visits: Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$7,571
Oceanview
$8,894
Balcony
$10,697
Suite
$15,637
From (Per Person)
A$7,571
Save 118
Per Person
View Trip
15 Day The best of Chilean Fjords with Ponant
Cruise
 (2)

15 Days (14 Nights) Valparaiso to Buenos Aires
Operator: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Oct 2028
Visits: Chile, Argentina
Exclusive Savings
Oceanview
$15,427
Balcony
$16,524
Suite
$26,709
From (Per Person)
A$15,427
Save 436
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Operator: Oceania
Ship: Oceania Insignia
Departure: 03 January 2027
Visits: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$10,994
Oceanview
$11,615
Balcony
$18,182
From (Per Person)
A$10,994
Save 2,256
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Maceio
Operator: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,507
From (Per Person)
A$2,507
Per Person
View Trip
15 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ships: Celebrity Equinox
Departures: Dec 2026 to Feb 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$2,727
Oceanview
$3,031
Balcony
$3,168
Suite
$9,777
From (Per Person)
A$2,727
Save 2,852
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Exclusive Savings
Inside
$7,951
Oceanview
$8,575
Balcony
$11,297
Suite
$22,712
From (Per Person)
A$7,951
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 23 January 2027
Visits: Brazil
Exclusive Savings
Inside
$1,429
Oceanview
$1,557
Balcony
$1,924
Suite
$2,728
From (Per Person)
A$1,429
Per Person
View Trip
Results: 1-29 of 441

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South & Central America Cruises

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Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Rome Cruises from Fort Lauderdale to San Juan Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to Vancouver Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Itajai to Itajai Cruises from Lima to Guayaquil Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to Miami Cruises from New York to Fort Lauderdale Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Quito Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Lisbon Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to Lisbon Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Diego to Fort Lauderdale Cruises from San Diego to Vancouver Cruises from San Juan to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Ushuaia to Ushuaia Cruises from Valparaiso to Buenos Aires Cruises from Vancouver to Vancouver Cruises from Vancouver to Los Angeles

Country Routes

Cruises from Peru to Argentina Cruises from Brazil to Ecuador Cruises from USA to Portugal Cruises from USA to Germany Cruises from Dominican Republic to Puerto Rico Cruises from England to Holland Cruises from France to Portugal Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Iceland to France Cruises from Brazil to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Puerto Rico to Dominican Republic Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to Singapore Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from USA to New Zealand Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Germany to USA Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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