South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 215 cruises around South America. Compare cruises, read past passenger reviews and enjoy exclusive savings on every departure.

  215 Cruises Found

South America - Buenos Aires

15 Days Buenos Aires to San Antonio
Operated By: Norwegian Cruise Line (Cruise)
Visit 4 different countries on this 14 night cruise with Norwegian Cruise Line, beginning your journey in Buenos Aires and travelling through to San Antonio.
Departures: Jan 2020 to Feb 2020 (3 Departures)
Regions: South America
 
From
$1,618

Highlights of South America & Chilean Fjords Cruise

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel (Guided Tour & Cruise)
Tour through 5 different countries on this 33 day guided tour & cruise with Travelmarvel, beginning your journey in Rio de Janeiro and travelling through to Lima....
Departures: Nov 2020 to Feb 2021 (2 Departures)
Countries Visited: Brazil, Argentina, Uruguay, Chile, Peru
Save
$409
From
$12,200

Patagonia & Chilean Fjords Explorer

14 Days Santiago to Buenos Aires
Operated By: APT (Expedition Cruise)
Embark on a 13 night expedition cruise with APT visiting Chile & Argentina, beginning your journey in Santiago and travelling through to Buenos Aires.
Departs: 04 November 2020
Regions: South America
Save
$3,461
From
$13,484

South America & the Chilean Fjords

18 Days Buenos Aires to Santiago
Operated By: Viking (Cruise)
Visit 4 different countries on this 17 night cruise with Viking, beginning your journey in Buenos Aires and travelling through to Santiago.
Departures: Jan 2020 to Feb 2022 (8 Departures)
Regions: South America
Save
$791
From
$9,404

Tango, Salsa & Samba Voyage

14 Days Buenos Aires to Buenos Aires
Operated By: Azamara (Cruise)
Embark on a 13 night cruise with Azamara visiting Argentina, Uruguay & Brazil, beginning and ending your journey in Buenos Aires.
Departs: 08 December 2019
Regions: South America
 
From
$1,877

Baltra to San Cristobal

8 Days Baltra Island to San Cristobal Island
Operated By: Silversea (Expedition Cruise)
Join Silversea on this 7 night Galapagos expedition cruise, beginning your journey in Baltra Island and travelling through to San Cristobal Island.
Departures: Aug 2020 to Sep 2021 (29 Departures)
Regions: South America
 
From
$13,410

Charms Of South America

11 Days Rio de Janeiro to Buenos Aires
Operated By: Regent Seven Seas (Cruise)
Embark on a 10 night cruise with Regent Seven Seas visiting Brazil, Uruguay & Argentina, beginning your journey in Rio de Janeiro and travelling through to Buenos Ai...
Departs: 23 November 2021
Regions: South America
Save
$5,072
From
$6,828

Radiant Rhythms

13 Days Rio de Janeiro to Buenos Aires
Operated By: Oceania (Cruise)
Embark on a 12 night cruise with Oceania visiting Brazil, Uruguay & Argentina, beginning your journey in Rio de Janeiro and travelling through to Buenos Aires....
Departs: 12 February 2020
Regions: South America
Save
$4,029
From
$5,491

Antarctic Insights

30 Days San Antonio to Rio de Janeiro
Operated By: Regent Seven Seas (Cruise)
Visit 6 different countries on this 29 night cruise with Regent Seven Seas, beginning your journey in San Antonio and travelling through to Rio de Janeiro.
Departs: 31 January 2022
Regions: Antarctica, South America
Save
$9,822
From
$25,758
 (2 Reviews)

Best of South America & Galapagos (Flights Included)

36 Days Buenos Aires to Buenos Aires
Operated By: Bunnik (Small Group Tour & Cruise)
“Our tour guide Pepe (Jose Valdivia) was one of the best tour guides we've ever had. His caring, cheerful and positive attitude made this tour more enjoyable.”
Departs: 03 February 2020
Countries Visited: Chile, Galapagos, Peru, Argentina, Brazil
Save
$348
From
$19,647

Chile & Argentina Cruise

15 Days San Antonio to Buenos Aires
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Chile, Argentina & Uruguay, beginning your journey in San Antonio and travelling through to Buenos Aires....
Departures: Jan 2020 to Jan 2022 (4 Departures)
Regions: South America
 
From
$2,469

Spirit of Peru with Antarctica Cruise

22 Days Lima to Buenos Aires
Operated By: APT (Guided Tour & Cruise)
Travel to South & Central America and journey through Peru, Argentina & Antarctica on this 22 day guided tour & cruise with APT.
Departs: 08 February 2020
Countries Visited: Peru, Argentina, Antarctica
Save
$808
From
$22,187

Colombia, Ecuador & Peru Voyage

17 Days Miami to Lima
Operated By: Azamara (Cruise)
Visit 6 different countries on this 16 night cruise with Azamara, beginning your journey in Miami and travelling through to Lima.
Departs: 07 January 2022
Regions: South America
 
From
$6,787

Galápagos - East, Central, & West Islands aboard the Eden

10 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 9 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Feb 2020 to Dec 2020 (13 Departures)
Regions: South America
Save
$234
From
$5,394

A Taste of Galapagos

6 Days Santa Cruz Island to Baltra Island
Operated By: Exodus (Adventure Cruise)
Embark on a 5 night adventure cruise with Exodus visiting Ecuador & Galapagos, beginning your journey in Santa Cruz Island and travelling through to Baltra Island....
Departures: Jan 2020 to Dec 2020 (12 Departures)
Regions: South America
Save
$192
From
$4,607

Complete Galápagos - Eden

17 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 16 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jun 2020 to Dec 2020 (8 Departures)
Regions: South America
Save
$410
From
$9,599

New Year's Eve in Rio Voyage

16 Days Buenos Aires to Buenos Aires
Operated By: Azamara (Cruise)
Embark on a 15 night cruise with Azamara visiting Argentina, Uruguay & Brazil, beginning and ending your journey in Buenos Aires.
Departs: 21 December 2020
Regions: South America
 
From
$7,363

Galápagos – Western & Central Islands aboard the Reina Silvia Voyager

10 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 9 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jul 2020 to Dec 2021 (36 Departures)
Regions: South America
Save
$355
From
$8,015

Chilean Fjords Voyage

16 Days Buenos Aires to San Antonio
Operated By: Azamara (Cruise)
Visit 4 different countries on this 15 night cruise with Azamara, beginning your journey in Buenos Aires and travelling through to San Antonio.
Departs: 20 January 2020
Regions: South America
 
From
$3,031

Galápagos - West & Central Islands aboard the Monserrat

10 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 9 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jan 2020 to Sep 2020 (13 Departures)
Regions: South America
Save
$242
From
$5,567

Galapagos Explorer: Southern Islands (Grand Queen Beatriz)

7 Days Quito to Quito
Operated By: Intrepid (Expedition Cruise)
Embark on a 6 night expedition cruise with Intrepid visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Dec 2019 to Dec 2021 (44 Departures)
Regions: South America
Save
$1,332
From
$3,985

Brazil Highlights with Antarctica Cruise

20 Days Rio de Janeiro to Buenos Aires
Operated By: APT (Guided Tour & Cruise)
Travel to South & Central America and journey through Brazil, Argentina & Antarctica on this 20 day guided tour & cruise with APT.
Departs: 08 February 2020
Countries Visited: Brazil, Argentina, Antarctica
Save
$802
From
$21,743

Brazil Highlights with Antarctica Cruise

20 Days Buenos Aires to Rio de Janeiro
Operated By: APT (Guided Tour & Cruise)
Travel to South & Central America and journey through Argentina, Antarctica & Brazil on this 20 day guided tour & cruise with APT.
Departs: 15 February 2020
Countries Visited: Argentina, Antarctica, Brazil
Save
$863
From
$21,743

Valparaiso to Ushuaia

13 Days Valparaiso to Ushuaia
Operated By: Silversea (Cruise)
Ship: Silver Cloud
Embark on a 12 night cruise with Silversea visiting Chile & Argentina, beginning your journey in Valparaiso and travelling through to Ushuaia.
Departs: 04 November 2020
Regions: South America
 
From
$9,990

Argentina & Chile Cruise

15 Days Buenos Aires to San Antonio
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Argentina, Uruguay & Chile, beginning your journey in Buenos Aires and travelling through to San Antonio....
Departures: Dec 2021 to Feb 2022 (3 Departures)
Regions: South America
 
From
$2,826

Picturesque Patagonia

17 Days Buenos Aires to San Antonio
Operated By: Oceania (Cruise)
Visit 4 different countries on this 16 night cruise with Oceania, beginning your journey in Buenos Aires and travelling through to San Antonio.
Departs: 19 December 2019
Regions: South America
Save
$4,032
From
$10,908

Galapagos Voyager: Central Islands (Grand Queen Beatriz)

14 Days Quito to Quito
Operated By: Intrepid (Expedition Cruise)
Embark on a 13 night expedition cruise with Intrepid visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Dec 2019 to Dec 2021 (38 Departures)
Regions: South America
Save
$2,848
From
$9,725

Brazilian Spotlight

11 Days Buenos Aires to Rio de Janeiro
Operated By: Oceania (Cruise)
Embark on a 10 night cruise with Oceania visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Rio de Janeiro....
Departs: 09 March 2021
Regions: South America
Save
$3,541
From
$4,239

Antarctic Peninsula, Falkland Islands & South Georgia

20 Days Ushuaia to Ushuaia
Operated By: Peregrine (Expedition Cruise)
Visit 4 different countries on this 19 night expedition cruise with Peregrine, beginning and ending your journey in Ushuaia.
Departures: Feb 2020 to Feb 2021 (4 Departures)
Regions: Antarctica, South America
Save
$704
From
$23,520

Chile & Argentina Holiday

15 Days San Antonio to Buenos Aires
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Chile, Argentina & Uruguay, beginning your journey in San Antonio and travelling through to Buenos Aires....
Departs: 19 December 2021
Regions: South America
 
From
$3,529

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