All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 225 cruises around South America. Compare cruises, read past passenger reviews and enjoy exclusive savings on every departure.

  225 Cruises Found
Cruise  

14 Days Santiago to Buenos Aires
Operated By: APT (Expedition Cruise)
Embark on a 13 night expedition cruise with APT visiting Chile & Argentina, beginning your journey in Santiago and travelling through to Buenos Aires.
Departs: 04 November 2020
Regions: South America
Save
$ 581
From
$ 13,934
Cruise  

18 Days Buenos Aires to Santiago
Operated By: Viking (Cruise)
Visit 4 different countries on this 17 night cruise with Viking, beginning your journey in Buenos Aires and travelling through to Santiago.
Departures: Nov 2020 to Feb 2022 (6 Departures)
Regions: South America
Save
$ 1,060
From
$ 8,968
Cruise  

8 Days Baltra Island to San Cristobal Island
Operated By: Silversea (Expedition Cruise)
Join Silversea on this 7 night Galapagos expedition cruise, beginning your journey in Baltra Island and travelling through to San Cristobal Island.
Exclusive: Fly Offer Available
Departures: Jul 2020 to Sep 2021 (30 Departures)
Regions: South America
 
From
$ 13,590
Cruise  

11 Days Rio de Janeiro to Buenos Aires
Operated By: Regent Seven Seas (Cruise)
Embark on a 10 night cruise with Regent Seven Seas visiting Brazil, Uruguay & Argentina, beginning your journey in Rio de Janeiro and travelling through to Buenos Ai...
Exclusive: Early Booking Savings + Bonus
Departs: 23 November 2021
Regions: South America
Save
$ 5,000
From
$ 7,320
Cruise  

30 Days San Antonio to Rio de Janeiro
Operated By: Regent Seven Seas (Cruise)
Visit 6 different countries on this 29 night cruise with Regent Seven Seas, beginning your journey in San Antonio and travelling through to Rio de Janeiro.
Exclusive: Early Booking Savings + Bonus
Departs: 31 January 2022
Regions: Antarctica, South America
Save
$ 9,500
From
$ 28,960
Cruise  

15 Days San Antonio to Buenos Aires
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Chile, Argentina & Uruguay, beginning your journey in San Antonio and travelling through to Buenos Aires....
Exclusive: Mutiple Deals Available
Departures: Dec 2020 to Jan 2022 (3 Departures)
Regions: South America
 
From
$ 5,029
Cruise  

17 Days Miami to Lima
Operated By: Azamara (Cruise)
Visit 6 different countries on this 16 night cruise with Azamara, beginning your journey in Miami and travelling through to Lima.
Exclusive: July Offer
Departs: 07 January 2022
Regions: South America
 
From
$ 6,787
Cruise  

10 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 9 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Sep 2020 to Dec 2021 (26 Departures)
Regions: South America
Save
$ 234
From
$ 5,394
Cruise  

20 Days Santiago to Buenos Aires
Operated By: Regent Seven Seas (Cruise)
Visit 5 different countries on this 19 night cruise with Regent Seven Seas, beginning your journey in Santiago and travelling through to Buenos Aires.
Exclusive: Early Booking Savings + Bonus
Departs: 31 January 2022
Regions: South America
Save
$ 6,350
From
$ 20,000
Cruise  

6 Days Santa Cruz Island to Baltra Island
Operated By: Exodus (Adventure Cruise)
Embark on a 5 night adventure cruise with Exodus visiting Ecuador & Galapagos, beginning your journey in Santa Cruz Island and travelling through to Baltra Island....
Departures: Nov 2020 to Dec 2020 (2 Departures)
Regions: South America
Save
$ 192
From
$ 4,607
Cruise  

17 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 16 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Sep 2020 to Dec 2021 (26 Departures)
Regions: South America
Save
$ 420
From
$ 9,599
Cruise  

16 Days Buenos Aires to Buenos Aires
Operated By: Azamara (Cruise)
Embark on a 15 night cruise with Azamara visiting Argentina, Uruguay & Brazil, beginning and ending your journey in Buenos Aires.
Exclusive: July Offer
Departs: 21 December 2020
Regions: South America
 
From
$ 5,794
Cruise  

10 Days Quito to Quito
Operated By: Explore (Expedition Cruise)
Embark on a 9 night expedition cruise with Explore visiting Galapagos & Ecuador, beginning and ending your journey in Quito.
Departures: Sep 2020 to Dec 2020 (9 Departures)
Regions: South America
Save
$ 272
From
$ 6,250
Cruise  

9 Days Guayaquil to Guayaquil
Operated By: Tauck (Small Ship Cruise)
Embark on a 8 night small ship cruise with Tauck visiting Ecuador & Galapagos, beginning and ending your journey in Guayaquil.
Exclusive: 1 Night Free!
Departures: Nov 2020 to Dec 2020 (3 Departures)
Regions: South America
Save
$ 221
From
$ 9,398
Cruise  

10 Days Quito to Quito
Operated By: Explore (Expedition Cruise)
Embark on a 9 night expedition cruise with Explore visiting Galapagos & Ecuador, beginning and ending your journey in Quito.
Departures: Sep 2020 to Dec 2020 (9 Departures)
Regions: South America
Save
$ 272
From
$ 6,250
Cruise  

10 Days Quito to Guayaquil
Operated By: Exodus (Expedition Cruise)
Embark on a 9 night expedition cruise with Exodus visiting Ecuador & Galapagos, beginning your journey in Quito and travelling through to Guayaquil.
Departures: Oct 2020 to Dec 2021 (13 Departures)
Regions: South America
Save
$ 378
From
$ 8,303
Cruise  

7 Days Quito to Quito
Operated By: Intrepid (Expedition Cruise)
Embark on a 6 night expedition cruise with Intrepid visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Oct 2020 to Dec 2021 (31 Departures)
Regions: South America
Save
$ 129
From
$ 5,745
Cruise  

5 Days Rio de Janeiro to Rio de Janeiro
Operated By: MSC Cruises (Cruise)
Ship: MSC Preziosa
Join MSC Cruises on this 4 night Brazil cruise, beginning and ending your journey in Rio de Janeiro.
Departs: 24 January 2021
Regions: South America
 
From
$ 759
Cruise  

32 Days Buenos Aires to Miami
Operated By: Oceania (Cruise)
Visit 6 different countries on this 31 night cruise with Oceania, beginning your journey in Buenos Aires and travelling through to Miami.
Exclusive: Early Booking Savings + OLife Choice
Departs: 09 March 2021
Regions: South America
Save
$ 9,250
From
$ 10,180
Cruise  

14 Days Quito to Quito
Operated By: Intrepid (Expedition Cruise)
Embark on a 13 night expedition cruise with Intrepid visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Oct 2020 to Dec 2021 (30 Departures)
Regions: South America
Save
$ 293
From
$ 12,115
Cruise  

15 Days San Antonio to Buenos Aires
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Chile, Argentina & Uruguay, beginning your journey in San Antonio and travelling through to Buenos Aires....
Exclusive: Mutiple Deals Available
Departs: 19 December 2021
Regions: South America
 
From
$ 4,739
Cruise  

11 Days Buenos Aires to Rio de Janeiro
Operated By: Oceania (Cruise)
Embark on a 10 night cruise with Oceania visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Rio de Janeiro....
Exclusive: Early Booking Savings + OLife Choice
Departs: 09 March 2021
Regions: South America
Save
$ 4,900
From
$ 3,160
Cruise  

20 Days Ushuaia to Ushuaia
Operated By: Peregrine (Expedition Cruise)
Visit 4 different countries on this 19 night expedition cruise with Peregrine, beginning and ending your journey in Ushuaia.
Departures: Nov 2020 to Feb 2021 (3 Departures)
Regions: Antarctica, South America
Save
$ 578
From
$ 26,166
Cruise  

22 Days Rio de Janeiro to Miami
Operated By: Oceania (Cruise)
Visit 4 different countries on this 21 night cruise with Oceania, beginning your journey in Rio de Janeiro and travelling through to Miami.
Exclusive: Early Booking Savings + OLife Choice
Departs: 26 February 2022
Regions: South America
Save
$ 6,350
From
$ 7,380
Cruise  

18 Days Santiago to Buenos Aires
Operated By: Viking (Cruise)
Visit 4 different countries on this 17 night cruise with Viking, beginning your journey in Santiago and travelling through to Buenos Aires.
Departures: Dec 2020 to Feb 2022 (6 Departures)
Regions: South America
Save
$ 1,060
From
$ 8,968
Cruise  

15 Days Rio de Janeiro to Bridgetown
Operated By: Viking (Cruise)
Embark on a 14 night cruise with Viking visiting Brazil, French Guiana & Barbados, beginning your journey in Rio de Janeiro and travelling through to Bridgetown....
Exclusive: Save up to $2000
Departs: 26 March 2022
Regions: South America
Save
$ 830
From
$ 10,665
Cruise  

10 Days Quito to Guayaquil
Operated By: Exodus (Expedition Cruise)
Embark on a 9 night expedition cruise with Exodus visiting Ecuador & Galapagos, beginning your journey in Quito and travelling through to Guayaquil.
Departures: Oct 2020 to Dec 2021 (8 Departures)
Regions: South America
Save
$ 419
From
$ 9,455
Cruise  

4 Days Santos to Santos
Operated By: MSC Cruises (Cruise)
Ship: MSC Preziosa
Join MSC Cruises on this 3 night Brazil cruise, beginning and ending your journey in Santos.
Exclusive: Early Booking Savings
Departures: Nov 2020 to Mar 2021 (3 Departures)
Regions: South America
 
From
$ 399
Cruise  

7 Days Quito to Quito
Operated By: Intrepid (Expedition Cruise)
Embark on a 6 night expedition cruise with Intrepid visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Oct 2020 to Dec 2021 (21 Departures)
Regions: South America
Save
$ 113
From
$ 5,119
Cruise  

22 Days Lima to Buenos Aires
Operated By: Regent Seven Seas (Cruise)
Visit 5 different countries on this 21 night cruise with Regent Seven Seas, beginning your journey in Lima and travelling through to Buenos Aires.
Exclusive: Mutiple Deals Available
Departs: 21 February 2021
Regions: South America
 
From
$ 14,600

Results 1-30 of 225