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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 2,138 expeditions and cruises around South America traveling with the world's leading cruise lines.
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157 Days
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351 Cruises (2,138 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save (per person) 264
From (per person) 11,321
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2025 to Dec 2026
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 165
From (per person) 7,708
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2025 to Dec 2026
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save (per person) 854
From (per person) 4,451
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (4)

18 Days (17 Nights) Buenos Aires to Santiago
Operated By: Viking Cruises
Ship: Viking Jupiter
Departures: Nov 2025 to Feb 2027
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Viking $1,799 Air Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,699
SUITE
$11,999
Save (per person) 700
From (per person) 7,699
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Nov 2025 to Dec 2026
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 226
From (per person) 10,555
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2025 to Dec 2026
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save (per person) 1,656
From (per person) 6,209
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Aug 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save (per person) 227
From (per person) 9,738
View Trip
15 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 23 February 2027
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$2,314
OCEANVIEW
$2,564
BALCONY
$3,564
SUITE
$4,664
From (per person) 2,314
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 29 December 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$1,956
OCEANVIEW
-
BALCONY
$2,586
SUITE
-
From (per person) 1,956
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Nov 2026 to Nov 2026
Countries Visited: Chile, Argentina
INSIDE
-
OCEANVIEW
-
BALCONY
$11,350
SUITE
$18,590
From (per person) 11,350
View Trip
10 Day Galapagos - Central, North, South & East Islands aboard the Archipel I with Explore!
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Explore!
Departures: Jul 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Sign Up Savings
Save (per person) 903
From (per person) 6,747
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 17 March 2027
Countries Visited: Argentina, Uruguay, Brazil
2 for 1 Fares + Fly Free Premium Economy2 for 1 Fares + Fly Free Business Class
INSIDE
-
OCEANVIEW
-
BALCONY
$10,600
SUITE
$14,000
Save (per person) 12,390
From (per person) 10,600
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departures: Feb 2026 to Mar 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$15,400
SUITE
$22,000
From (per person) 15,400
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Nov 2025 to Apr 2026
Countries Visited: Brazil
Escape To Sea
INSIDE
$649
OCEANVIEW
$819
BALCONY
$1,049
SUITE
$1,529
From (per person) 649
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2025 to Mar 2026
Countries Visited: Uruguay, Argentina, Brazil
Escape To Sea
INSIDE
$1,513
OCEANVIEW
$1,764
BALCONY
$1,686
SUITE
$2,473
From (per person) 1,513
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operated By: Tauck
Departures: Mar 2026 to Jul 2026
Countries Visited: Ecuador, Galapagos
From (per person) 6,690
View Trip
9 Day Brazil Intensive Cruise: Rio De Janeiro, Paraty & Ilhabela with Azamara Cruises
Cruise
 (3)

9 Days (8 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 31 January 2026
Countries Visited: Brazil, Uruguay, Argentina
INSIDE
$2,399
OCEANVIEW
$2,499
BALCONY
$3,019
SUITE
$4,929
From (per person) 2,399
View Trip
10 Day Classic Galapagos: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Oct 2025 to Dec 2026
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 172
From (per person) 8,041
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Brazil, Uruguay, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$8,500
BALCONY
$10,200
SUITE
$14,400
From (per person) 8,500
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 23 December 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$711
OCEANVIEW
$861
BALCONY
$991
SUITE
$1,401
From (per person) 711
View Trip
8 Day Galapagos Outer Loop Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Cruise Line: Celebrity Cruises
Ship: Celebrity Flora
Departures: Sep 2025 to Dec 2027
Countries Visited: Galapagos
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,245
Save (per person) 4,646
From (per person) 8,245
View Trip
15 Day South America Passage with Holland America
Cruise
 (2)

15 Days (14 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Dec 2025 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$2,099
OCEANVIEW
$2,149
BALCONY
$2,899
SUITE
$3,699
From (per person) 2,099
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 16 December 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$908
OCEANVIEW
-
BALCONY
$1,211
SUITE
$2,102
From (per person) 908
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Mar 2026 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save (per person) 311
From (per person) 12,743
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2026 to Sep 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 14,190
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 17 February 2026
Countries Visited: Argentina, Brazil, Uruguay
Escape To Sea
INSIDE
$1,670
OCEANVIEW
-
BALCONY
$2,165
SUITE
$2,948
From (per person) 1,670
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 December 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$1,537
OCEANVIEW
$1,657
BALCONY
$2,167
SUITE
$2,467
From (per person) 1,537
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departures: Aug 2026 to Dec 2026
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$21,400
SUITE
$31,300
From (per person) 21,400
View Trip
27 Day Treasures of South America: Chilean Fjords to the Iguazu falls - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Chile, Brazil
2 for 1 Fares + Fly Free Premium Economy2 for 1 Fares + Fly Free Business Class
INSIDE
-
OCEANVIEW
-
BALCONY
$21,348
SUITE
$45,348
Save (per person) 14,607
From (per person) 21,348
View Trip
19 Day Buenos Aires to Valparaiso with Silversea
Cruise

19 Days (18 Nights) Buenos Aires to Valparaiso
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 26 February 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$13,600
BALCONY
$16,100
SUITE
$26,900
From (per person) 13,600
View Trip
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South & Central America Cruises

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Travel Styles

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Cities

Baltra Island Barcelona Bridgetown Buenos Aires Funchal Lima Lisbon Manaus Montevideo Panama City Quito Rio de Janeiro San Antonio Santiago Santiago Santiago Santos Sao Paulo Tahiti Ushuaia Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to London Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to London Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Paris to Paris Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from San Antonio to Buenos Aires Cruises from San Juan to Bridgetown Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Venice to Barcelona Cruises from Venice to Rome

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Germany to England Cruises from Canada to Japan Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to Barbados Cruises from Puerto Rico to USA Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from USA to Japan Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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