All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 218 cruises around South America. Compare cruises, read past passenger reviews and enjoy exclusive savings on every departure.

  218 Cruises Found

Chilean Fjords & Cape Horn

13 Days Santiago to Ushuaia
Operated By: Scenic (Discovery Voyage)
Embark on a 12 night discovery voyage with Scenic visiting Argentina & Chile, beginning your journey in Santiago and travelling through to Ushuaia.
Exclusive: $1250 Air Credit
Departs: 29 October 2020
Regions: South America
Save
$484
From
$15,636

South America - Buenos Aires

15 Days Buenos Aires to San Antonio
Operated By: Norwegian Cruise Line (Cruise)
Visit 4 different countries on this 14 night cruise with Norwegian Cruise Line, beginning your journey in Buenos Aires and travelling through to San Antonio.
Exclusive: Free At Sea
Departs: 29 February 2020
Regions: South America
 
From
$1,607

Highlights of South America & Chilean Fjords Cruise

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel (Guided Tour & Cruise)
Tour through 5 different countries on this 33 day guided tour & cruise with Travelmarvel, beginning your journey in Rio de Janeiro and travelling through to Lima....
Departs: 26 February 2021
Countries Visited: Brazil, Argentina, Uruguay, Chile, Peru
Save
$409
From
$12,586

Patagonia & Chilean Fjords Explorer

14 Days Santiago to Buenos Aires
Operated By: APT (Expedition Cruise)
Embark on a 13 night expedition cruise with APT visiting Chile & Argentina, beginning your journey in Santiago and travelling through to Buenos Aires.
Departs: 04 November 2020
Regions: South America
Save
$581
From
$16,364

South America & the Chilean Fjords

18 Days Buenos Aires to Santiago
Operated By: Viking (Cruise)
Visit 4 different countries on this 17 night cruise with Viking, beginning your journey in Buenos Aires and travelling through to Santiago.
Exclusive: Two Night Extension
Departures: Nov 2020 to Feb 2022 (6 Departures)
Regions: South America
Save
$333
From
$9,695

Baltra to San Cristobal

8 Days Baltra Island to San Cristobal Island
Operated By: Silversea (Expedition Cruise)
Join Silversea on this 7 night Galapagos expedition cruise, beginning your journey in Baltra Island and travelling through to San Cristobal Island.
Departures: Aug 2020 to Sep 2021 (29 Departures)
Regions: South America
 
From
$13,410

Charms Of South America

11 Days Rio de Janeiro to Buenos Aires
Operated By: Regent Seven Seas (Cruise)
Embark on a 10 night cruise with Regent Seven Seas visiting Brazil, Uruguay & Argentina, beginning your journey in Rio de Janeiro and travelling through to Buenos Ai...
Exclusive: Early Booking Savings + Bonus
Departs: 23 November 2021
Regions: South America
Save
$4,900
From
$7,000

Antarctic Insights

30 Days San Antonio to Rio de Janeiro
Operated By: Regent Seven Seas (Cruise)
Visit 6 different countries on this 29 night cruise with Regent Seven Seas, beginning your journey in San Antonio and travelling through to Rio de Janeiro.
Exclusive: Early Booking Savings + Bonus
Departs: 31 January 2022
Regions: Antarctica, South America
Save
$9,150
From
$26,430

Chile & Argentina Cruise

15 Days San Antonio to Buenos Aires
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Chile, Argentina & Uruguay, beginning your journey in San Antonio and travelling through to Buenos Aires....
Exclusive: Online Savings + Sail Your Way and Bonus Perk
Departures: Dec 2020 to Jan 2022 (3 Departures)
Regions: South America
 
From
$3,874

Antarctic Voyage with Spirit of Peru

22 Days Lima to Buenos Aires
Operated By: APT (Guided Tour & Cruise)
Travel to South & Central America and journey through Peru, Argentina & Antarctica on this 22 day guided tour & cruise with APT.
Departs: 28 January 2021
Countries Visited: Peru, Argentina, Antarctica
Save
$841
From
$23,054

Colombia, Ecuador & Peru Voyage

17 Days Miami to Lima
Operated By: Azamara (Cruise)
Visit 6 different countries on this 16 night cruise with Azamara, beginning your journey in Miami and travelling through to Lima.
Departs: 07 January 2022
Regions: South America
 
From
$6,787

Galápagos - East, Central, & West Islands aboard the Eden

10 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 9 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jun 2020 to Dec 2021 (29 Departures)
Regions: South America
Save
$976
From
$4,664

A Taste of Galapagos

6 Days Santa Cruz Island to Baltra Island
Operated By: Exodus (Adventure Cruise)
Embark on a 5 night adventure cruise with Exodus visiting Ecuador & Galapagos, beginning your journey in Santa Cruz Island and travelling through to Baltra Island....
Departures: Mar 2020 to Dec 2020 (11 Departures)
Regions: South America
Save
$192
From
$4,607

Callao to Punta Arenas

18 Days Lima to Punta Arenas
Operated By: Silversea (Cruise)
Ship: Silver Cloud
Embark on a 17 night cruise with Silversea visiting Peru & Chile, beginning your journey in Lima and travelling through to Punta Arenas.
Departs: 28 October 2020
Regions: South America
 
From
$14,220

Complete Galápagos - Eden

17 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 16 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jun 2020 to Dec 2021 (29 Departures)
Regions: South America
Save
$1,744
From
$8,299

New Year's Eve in Rio Voyage

16 Days Buenos Aires to Buenos Aires
Operated By: Azamara (Cruise)
Embark on a 15 night cruise with Azamara visiting Argentina, Uruguay & Brazil, beginning and ending your journey in Buenos Aires.
Exclusive: Wave Offer
Departs: 21 December 2020
Regions: South America
 
From
$4,763

Galápagos - West & Central Islands aboard the Monserrat

10 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 9 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jun 2020 to Dec 2021 (32 Departures)
Regions: South America
Save
$1,016
From
$4,913

Galapagos Islands (Itinerary B)

10 Days Quito to Guayaquil
Operated By: Exodus (Expedition Cruise)
Embark on a 9 night expedition cruise with Exodus visiting Ecuador & Galapagos, beginning your journey in Quito and travelling through to Guayaquil.
Departures: Mar 2020 to Dec 2020 (7 Departures)
Regions: South America
Save
$346
From
$8,303

Galapagos Explorer: Southern Islands (Grand Queen Beatriz)

7 Days Quito to Quito
Operated By: Intrepid (Expedition Cruise)
Embark on a 6 night expedition cruise with Intrepid visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Mar 2020 to Dec 2021 (40 Departures)
Regions: South America
Save
$126
From
$5,745

Antarctic Voyage with Brazil Highlights

20 Days Rio de Janeiro to Buenos Aires
Operated By: APT (Guided Tour & Cruise)
Travel to South & Central America and journey through Brazil, Argentina & Antarctica on this 20 day guided tour & cruise with APT.
Departs: 30 January 2021
Countries Visited: Brazil, Argentina, Antarctica
Save
$839
From
$22,556

Brazil Highlights with Antarctica Cruise

20 Days Buenos Aires to Rio de Janeiro
Operated By: APT (Guided Tour & Cruise)
Travel to South & Central America and journey through Argentina, Antarctica & Brazil on this 20 day guided tour & cruise with APT.
Departs: 04 February 2021
Countries Visited: Argentina, Antarctica, Brazil
Save
$863
From
$23,132

Valparaiso to Ushuaia

13 Days Valparaiso to Ushuaia
Operated By: Silversea (Cruise)
Ship: Silver Cloud
Embark on a 12 night cruise with Silversea visiting Chile & Argentina, beginning your journey in Valparaiso and travelling through to Ushuaia.
Departs: 04 November 2020
Regions: South America
 
From
$9,990

Argentina & Chile Cruise

15 Days Buenos Aires to San Antonio
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Argentina, Uruguay & Chile, beginning your journey in Buenos Aires and travelling through to San Antonio....
Exclusive: Online Savings + Sail Your Way and Bonus Perk
Departures: Dec 2021 to Feb 2022 (3 Departures)
Regions: South America
 
From
$3,619

Galapagos Voyager: Central Islands (Grand Queen Beatriz)

14 Days Quito to Quito
Operated By: Intrepid (Expedition Cruise)
Embark on a 13 night expedition cruise with Intrepid visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: May 2020 to Dec 2021 (36 Departures)
Regions: South America
Save
$267
From
$12,115

Brazilian Spotlight

11 Days Buenos Aires to Rio de Janeiro
Operated By: Oceania (Cruise)
Embark on a 10 night cruise with Oceania visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Rio de Janeiro....
Exclusive: Early Booking Savings + OLife Choice
Departs: 09 March 2021
Regions: South America
Save
$3,500
From
$4,980

Antarctic Peninsula, Falkland Islands & South Georgia

20 Days Ushuaia to Ushuaia
Operated By: Peregrine (Expedition Cruise)
Visit 4 different countries on this 19 night expedition cruise with Peregrine, beginning and ending your journey in Ushuaia.
Departures: Feb 2020 to Feb 2021 (4 Departures)
Regions: Antarctica, South America
Save
$14,502
From
$18,092

Chile & Argentina Holiday

15 Days San Antonio to Buenos Aires
Operated By: Celebrity Cruises (Cruise)
Embark on a 14 night cruise with Celebrity Cruises visiting Chile, Argentina & Uruguay, beginning your journey in San Antonio and travelling through to Buenos Aires....
Exclusive: Online Savings + Sail Your Way and Bonus Perk
Departs: 19 December 2021
Regions: South America
 
From
$4,339

Brazil's Vibrant Coast

15 Days Rio de Janeiro to Bridgetown
Operated By: Viking (Cruise)
Embark on a 14 night cruise with Viking visiting Brazil, French Guiana & Barbados, beginning your journey in Rio de Janeiro and travelling through to Bridgetown....
Departs: 26 March 2022
Regions: South America
Save
$830
From
$10,665

Panama Canal Adventure Voyage

14 Days Lima to Miami
Operated By: Azamara (Cruise)
Visit 5 different countries on this 13 night cruise with Azamara, beginning your journey in Lima and travelling through to Miami.
Departs: 23 March 2020
Regions: Caribbean, South America
 
From
$2,748

Galapagos Encounter (Itinerary D)

10 Days Quito to Guayaquil
Operated By: Exodus (Expedition Cruise)
Embark on a 9 night expedition cruise with Exodus visiting Ecuador & Galapagos, beginning your journey in Quito and travelling through to Guayaquil.
Departures: Jul 2020 to Dec 2020 (6 Departures)
Regions: South America
Save
$394
From
$9,455

Mystical Fjords

21 Days Buenos Aires to Lima
Operated By: Oceania (Cruise)
Visit 5 different countries on this 20 night cruise with Oceania, beginning your journey in Buenos Aires and travelling through to Lima.
Exclusive: OLife Ultimate
Departs: 24 February 2020
Regions: South America
Save
$5,468
From
$8,262

Results 1-30 of 218