All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 279 cruises around South America. Compare cruises, read past passenger reviews and enjoy exclusive savings on every departure.

  279 Cruises Found
Cruise  

18 Days Buenos Aires to Santiago
Operated By: Viking Cruises (Cruise)
Visit 4 different countries on this 17 night cruise with Viking Cruises, beginning your journey in Buenos Aires and travelling through to Santiago.
Exclusive: Explore More Offer
Departures: Dec 2021 to Feb 2023 (6 Departures)
Regions: South America
Save
$ 1,767
From
$ 8,628
Cruise  

8 Days Baltra Island to San Cristobal Island
Operated By: Silversea (Expedition Cruise)
Join Silversea on this 7 night Galapagos expedition cruise, beginning your journey in Baltra Island and travelling through to San Cristobal Island.
Exclusive: Fly Offer Available
Departures: Jun 2021 to Sep 2021 (9 Departures)
Regions: South America
 
From
$ 15,120
Cruise  

18 Days Valparaiso to Buenos Aires
Operated By: Hurtigruten (Expedition Cruise)
Embark on a 17 night expedition cruise with Hurtigruten visiting Chile, Antarctica & Argentina, beginning your journey in Valparaiso and travelling through to Buenos...
Departs: 02 November 2021
Regions: Antarctica, South America
 
From
$ 13,661
Cruise  

20 Days Buenos Aires to Manaus
Operated By: Seabourn (Expedition Cruise)
Embark on a 19 night expedition cruise with Seabourn visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Manaus....
Departs: 10 March 2023
Regions: South America
 
From
$ 19,491
Cruise  

11 Days Buenos Aires to Buenos Aires
Operated By: MSC Cruises (Cruise)
Embark on a 10 night cruise with MSC Cruises visiting Argentina, Uruguay & Brazil, beginning and ending your journey in Buenos Aires.
Exclusive: Early Booking
Departs: 26 December 2021
Regions: South America
 
From
$ 1,479
Cruise  

21 Days Buenos Aires to Lima
Operated By: Oceania Cruises (Cruise)
Visit 5 different countries on this 20 night cruise with Oceania Cruises, beginning your journey in Buenos Aires and travelling through to Lima.
Exclusive: Early Booking Savings + OLife Choice
Departs: 27 February 2023
Regions: South America
Save
$ 4,750
From
$ 7,260
Cruise  

15 Days Buenos Aires to Fortaleza
Operated By: Silversea (Cruise)
Ship: Silver Wind
Embark on a 14 night cruise with Silversea visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Fortaleza....
Exclusive: Fly Offers Available
Departs: 21 March 2022
Regions: South America
 
From
$ 9,680
Cruise  

9 Days Sao Paulo to Sao Paulo
Operated By: MSC Cruises (Cruise)
Ship: MSC Seaside
Join MSC Cruises on this 8 night Brazil cruise, beginning and ending your journey in Sao Paulo.
Exclusive: Early Booking
Departs: 30 December 2021
Regions: South America
 
From
$ 1,899
Cruise  

18 Days Buenos Aires to Buenos Aires
Operated By: Azamara Cruises (Cruise)
Visit 4 different countries on this 17 night cruise with Azamara Cruises, beginning and ending your journey in Buenos Aires.
Exclusive: Onboard Credit US $600
Departs: 24 January 2023
Regions: South America
 
From
$ 8,356
Cruise  

4 Days Rio de Janeiro to Rio de Janeiro
Operated By: MSC Cruises (Cruise)
Ship: MSC Preziosa
Join MSC Cruises on this 3 night Brazil cruise, beginning and ending your journey in Rio de Janeiro.
Exclusive: Early Booking
Departs: 05 March 2022
Regions: South America
 
From
$ 449
Cruise  

56 Days London to London
Operated By: P&O (UK) Cruises (Cruise)
Visit 23 different countries on this 55 night cruise with P&O (UK) Cruises, beginning and ending your journey in London.
Departs: 07 January 2022
Regions: Transatlantic, Caribbean, South America
 
From
$ 10,249
Cruise  

32 Days Miami to Buenos Aires
Operated By: Oceania Cruises (Cruise)
Visit 6 different countries on this 31 night cruise with Oceania Cruises, beginning your journey in Miami and travelling through to Buenos Aires.
Exclusive: Early Booking Savings + OLife Choice
Departs: 18 December 2022
Regions: South America
Save
$ 6,100
From
$ 10,970
Cruise  

7 Days Quito to Quito
Operated By: Peregrine Adventures (Expedition Cruise)
Embark on a 6 night expedition cruise with Peregrine Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: May 2021 to Dec 2022 (34 Departures)
Regions: South America
Save
$ 135
From
$ 5,658
Cruise  

11 Days Buenos Aires to Rio de Janeiro
Operated By: Regent Seven Seas (Cruise)
Embark on a 10 night cruise with Regent Seven Seas visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Rio de Jane...
Exclusive: Mutiple Deals Available
Departs: 05 March 2023
Regions: South America
Save
$ 4,450
From
$ 10,410
Cruise  

32 Days Buenos Aires to Fort Lauderdale
Operated By: Holland America (Cruise)
Visit 9 different countries on this 31 night cruise with Holland America, beginning your journey in Buenos Aires and travelling through to Fort Lauderdale.
Departures: Mar 2022 to Mar 2023 (2 Departures)
Regions: South America
 
From
$ 8,179
Cruise  

20 Days Buenos Aires to Valparaiso
Operated By: Hurtigruten (Expedition Cruise)
Ship: MS Fram
Embark on a 19 night expedition cruise with Hurtigruten visiting Argentina, Antarctica & Chile, beginning your journey in Buenos Aires and travelling through to Valp...
Departs: 17 March 2022
Regions: Antarctica, South America
 
From
$ 12,734
Cruise  

9 Days Salvador to Salvador
Operated By: MSC Cruises (Cruise)
Ship: MSC Seaside
Join MSC Cruises on this 8 night Brazil cruise, beginning and ending your journey in Salvador.
Exclusive: Early Booking
Departs: 26 December 2021
Regions: South America
 
From
$ 1,899
Cruise  

13 Days Manaus to Praia
Operated By: Seabourn (Expedition Cruise)
Embark on a 12 night expedition cruise with Seabourn visiting Brazil, French Guiana & Cape Verde, beginning your journey in Manaus and travelling through to Praia....
Departs: 18 April 2023
Regions: South America
 
From
$ 10,815
Cruise  

10 Days Quito to Guayaquil
Operated By: Exodus Travels (Expedition Cruise)
Embark on a 9 night expedition cruise with Exodus Travels visiting Ecuador & Galapagos, beginning your journey in Quito and travelling through to Guayaquil....
Departures: Oct 2021 to Dec 2022 (14 Departures)
Regions: South America
Save
$ 398
From
$ 9,071
Cruise  

7 Days Rio de Janeiro to Rio de Janeiro
Operated By: MSC Cruises (Cruise)
Ship: MSC Preziosa
Join MSC Cruises on this 6 night Brazil cruise, beginning and ending your journey in Rio de Janeiro.
Exclusive: Early Booking
Departures: Dec 2021 to Feb 2022 (5 Departures)
Regions: South America
 
From
$ 699
Cruise  

7 Days Quito to Quito
Operated By: Intrepid Travel (Expedition Cruise)
Embark on a 6 night expedition cruise with Intrepid Travel visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jun 2021 to Dec 2022 (36 Departures)
Regions: South America
Save
$ 135
From
$ 5,658
Cruise  

6 Days Rio de Janeiro to Rio de Janeiro
Operated By: MSC Cruises (Cruise)
Ship: MSC Preziosa
Join MSC Cruises on this 5 night Brazil cruise, beginning and ending your journey in Rio de Janeiro.
Exclusive: Early Booking
Departs: 07 December 2021
Regions: South America
 
From
$ 579
Cruise  

11 Days Montevideo to Montevideo
Operated By: MSC Cruises (Cruise)
Embark on a 10 night cruise with MSC Cruises visiting Uruguay, Argentina & Brazil, beginning and ending your journey in Montevideo.
Exclusive: Early Booking
Departs: 25 December 2021
Regions: South America
 
From
$ 1,479
Cruise  

14 Days Quito to Quito
Operated By: Intrepid Travel (Expedition Cruise)
Embark on a 13 night expedition cruise with Intrepid Travel visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jul 2021 to Dec 2022 (30 Departures)
Regions: South America
Save
$ 310
From
$ 12,910
Cruise  

44 Days Miami to Buenos Aires
Operated By: Seabourn (Cruise)
Visit 9 different countries on this 43 night cruise with Seabourn, beginning your journey in Miami and travelling through to Buenos Aires.
Departs: 07 November 2021
Regions: Antarctica, South America
 
From
$ 30,923
Cruise  

22 Days Rio de Janeiro to Miami
Operated By: Oceania Cruises (Cruise)
Visit 4 different countries on this 21 night cruise with Oceania Cruises, beginning your journey in Rio de Janeiro and travelling through to Miami.
Exclusive: Early Booking Savings + OLife Choice
Departs: 26 February 2022
Regions: South America
Save
$ 5,750
From
$ 8,970
Cruise  

10 Days Quito to Quito
Operated By: G Adventures (Expedition Cruise)
Embark on a 9 night expedition cruise with G Adventures visiting Ecuador & Galapagos, beginning and ending your journey in Quito.
Departures: Jun 2021 to Dec 2022 (20 Departures)
Regions: South America
Save
$ 263
From
$ 5,394
Cruise  

11 Days Buenos Aires to Rio de Janeiro
Operated By: Silversea (Cruise)
Ship: Silver Moon
Embark on a 10 night cruise with Silversea visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Rio de Janeiro....
Exclusive: Early Booking Bonus
Departs: 12 February 2023
Regions: South America
 
From
$ 9,990
Cruise  

18 Days Santiago to Buenos Aires
Operated By: Viking Cruises (Cruise)
Visit 4 different countries on this 17 night cruise with Viking Cruises, beginning your journey in Santiago and travelling through to Buenos Aires.
Exclusive: Explore More Offer
Departures: Dec 2021 to Feb 2023 (6 Departures)
Regions: South America
Save
$ 1,306
From
$ 8,919
Cruise  

11 Days Buenos Aires to Rio de Janeiro
Operated By: Regent Seven Seas (Cruise)
Embark on a 10 night cruise with Regent Seven Seas visiting Argentina, Uruguay & Brazil, beginning your journey in Buenos Aires and travelling through to Rio de Jane...
Exclusive: Mutiple Deals Available
Departs: 19 February 2022
Regions: South America
Save
$ 4,200
From
$ 10,810

Results 1-30 of 279