Home > Cruises > South America Cruises > All Cruises

All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 1,722 expeditions and cruises around South America travelling with the world's leading cruise lines.
Filter Results
401 Cruises (1,722 Departures)
401 Cruises (1,722 Departures)
Departures
Show More...
Duration
2 Days
141 Days
Sub Regions
Show More...
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$200pp
$133,895pp
Countries
Show More...
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Oct 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$18,556
Save 446
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (2)

18 Days (17 Nights) Buenos Aires to Santiago
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Jan 2027 to Jan 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Balcony
$14,009
Suite
$22,339
From (Per Person)
A$14,009
Save 326
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departure: 29 September 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$12,472
Save 405
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Sep 2026 to Dec 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,447
Save 1,860
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$11,563
Save 266
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operator: Travelmarvel
Cruise Line: Holland America
Departures: Feb 2027 to Feb 2028
Trip Styles: Coach, Cruise, Scenic
Visits: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Exclusive Savings
Oceanview
$20,169
Balcony
$22,178
From (Per Person)
A$20,169
Save 2,352
Per Person
View Trip
15 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with Globus
New ReleaseTour + Cruise
 (1)

15 Days Lima to Guayaquil
Operator: Globus
Departures: Jun 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,639
Save 623
Per Person
View Trip
22 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Nazca Lines & the Amazon with Globus
New ReleaseTour + Cruise
 (1)

22 Days Lima to Quito
Operator: Globus
Departures: May 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$19,294
Save 798
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Buenos Aires
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Feb 2029
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Balcony
$12,000
Suite
$18,664
From (Per Person)
A$12,000
Save 1,495
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$9,420
Save 1,831
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,127
Save 396
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Divina
Departure: 05 February 2027
Visits: Brazil
Exclusive Savings
Inside
$1,248
Oceanview
$1,416
Balcony
$1,545
Suite
$1,851
From (Per Person)
A$1,248
Per Person
View Trip
15 Day Brazil Intensive Cruise: Salvador, Natal & Belem with Azamara Cruises
Cruise
 (6)

15 Days (14 Nights) Rio de Janeiro to Bridgetown
Operator: Azamara
Ship: Azamara Quest
Departure: 28 February 2028
Visits: Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$8,665
Oceanview
$10,210
Balcony
$12,324
Suite
$18,124
From (Per Person)
A$8,665
Save 604
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 27 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,132
Suite
$7,995
From (Per Person)
A$3,132
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 10 January 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,696
Oceanview
$1,835
Balcony
$2,181
Suite
$2,894
From (Per Person)
A$1,696
Per Person
View Trip
15 Day Patagonia & Argentina Holiday with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 December 2027
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$4,156
Oceanview
$4,606
Balcony
$5,191
Suite
$15,260
From (Per Person)
A$4,156
Save 2,427
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Operator: Oceania
Ship: Oceania Sirena
Departure: 19 January 2028
Visits: Peru, Chile
Your World Inclusions
Exclusive Savings
Inside
$6,669
Oceanview
$7,086
Balcony
$9,017
Suite
$12,877
From (Per Person)
A$6,669
Save 2,151
Per Person
View Trip
14 Day Barbados, French Guiana & Brazil Cruise: Bridgetown, Ile Royale & Rio De Janeiro with Azamara Cruises
Cruise
 (6)

14 Days (13 Nights) Bridgetown to Rio de Janeiro
Operator: Azamara
Ship: Azamara Journey
Departure: 25 January 2027
Visits: Barbados, Trinidad and Tobago, French Guiana, Brazil
Azamara Always Included
Exclusive Savings
Inside
$5,445
Oceanview
$6,140
Balcony
$7,757
Suite
$11,207
From (Per Person)
A$5,445
Save 84
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Operator: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina
Exclusive Savings
Oceanview
$2,731
Balcony
$2,906
Suite
$4,322
From (Per Person)
A$2,731
Save 62
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$2,241
Oceanview
$2,488
Balcony
$2,844
Suite
$3,537
From (Per Person)
A$2,241
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Feb 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,168
Suite
$1,653
From (Per Person)
A$852
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departure: 21 December 2026
Visits: Brazil
Exclusive Savings
Inside
$1,354
Oceanview
$1,433
Balcony
$1,612
Suite
$1,988
From (Per Person)
A$1,354
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
$4,619
From (Per Person)
A$1,280
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$7,476
Oceanview
$8,218
Balcony
$10,842
Suite
$15,049
From (Per Person)
A$7,476
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Inside
$3,195
Oceanview
-
Balcony
$4,417
Suite
$5,136
From (Per Person)
A$3,195
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Holland America
Ship: Nieuw Amsterdam
Departures: Nov 2027 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Exclusive Savings
Inside
$3,148
Oceanview
$3,445
Balcony
$4,732
Suite
$6,910
From (Per Person)
A$3,148
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,399
Oceanview
$1,647
Balcony
$1,983
Suite
$2,696
From (Per Person)
A$1,399
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (6)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Operator: Azamara
Ship: Azamara Quest
Departure: 16 February 2028
Visits: Argentina, Uruguay, Brazil
Azamara Always Included
Exclusive Savings
Inside
$7,799
Oceanview
$9,223
Balcony
$11,085
Suite
$16,029
From (Per Person)
A$7,799
Save 540
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$401
Suite
$669
From (Per Person)
A$253
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visits: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$4,327
Oceanview
$4,624
Balcony
$5,614
Suite
$8,039
From (Per Person)
A$4,327
Per Person
View Trip
Results: 1-30 of 401

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wildlife Cruises

Cities

Cruises from Baltra Island Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Itajai Cruises from Lima Cruises from Lisbon Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from San Antonio Cruises from Santiago Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valencia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to New York Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Reykjavik to New York Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to London Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Diego to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Vancouver to Los Angeles Cruises from Venice to Barcelona Cruises from Venice to Rome

Country Routes

Cruises from Peru to Argentina Cruises from Australia to England Cruises from USA to Germany Cruises from Italy to England Cruises from England to Holland Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from USA to New Zealand Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

All South America Tours Amazon Tours Argentina Tours Brazil Tours Chile Tours Colombia Tours Ecuador Tours Galapagos Tours Patagonia Tours Peru Tours
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations