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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 1,815 expeditions and cruises around South America travelling with the world's leading cruise lines.
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341 Cruises (1,815 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 242
From 15,892
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Apr 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 3,092
From 7,158
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7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,978
From 4,642
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33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Mar 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Brazil, Argentina, Uruguay, Falkland Islands (+2 more), Chile, Peru
Exclusive Deal
Save 1,544
From 16,860
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33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save 1,546
From 16,559
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26 Day Spirit of South America with Brazil Amazon and Galapagos Cruise with Globus
Tour + Cruise
 (1)

26 Days Manaus to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Oct 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 295
From 18,726
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10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,597
From 8,653
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26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 211
From 13,877
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18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (3)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Nov 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,400
SUITE
$18,805
Save 1,120
From 9,400
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8 Day Buenos Aires To Rio De Janeiro with Celebrity Cruises
Cruise
 (2)

8 Days (7 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 20 April 2024
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
$3,829
BALCONY
$2,105
SUITE
$6,292
Save 1,987
From 1,873
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16 Day Cape Horn & Strait of Magellan with Princess
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departure: 19 December 2024
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
INSIDE
$3,922
OCEANVIEW
-
BALCONY
$4,774
SUITE
$6,337
From 3,922
View Trip
32 Day Panama Canal, Inca & South America Discovery with Holland America
Cruise
 (1)

32 Days (31 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2024 to Nov 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+5 more), Peru, Chile, Argentina, Falkland Islands, Uruguay
Have It All Offer
INSIDE
$7,788
OCEANVIEW
$8,055
BALCONY
$9,927
SUITE
$12,946
From 7,788
View Trip
15 Day South America Passage with Holland America
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Have It All Offer
INSIDE
$4,022
OCEANVIEW
$4,160
BALCONY
$5,338
SUITE
$6,586
From 4,022
View Trip
10 Day Ocean Voyage: Hanga Roa - Ushuaia with Ponant
Cruise
 (1)

10 Days (9 Nights) Hanga Roa to Ushuaia
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 November 2024
Countries Visited: Easter Island, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$3,296
BALCONY
$3,551
SUITE
$5,315
Save 54
From 3,296
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (3)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Nov 2024 to Feb 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,697
SUITE
$18,805
Save 1,122
From 9,697
View Trip
18 Day Inca & Panama Canal Discovery with Holland America
Cruise
 (1)

18 Days (17 Nights) San Antonio to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Cayman Islands, USA
Have It All Offer
INSIDE
$4,749
OCEANVIEW
$4,887
BALCONY
$5,996
SUITE
$8,491
From 4,749
View Trip
32 Day South America, Inca & Panama Canal Discovery with Holland America
Cruise
 (1)

32 Days (31 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Panama, Cayman Islands, USA
Have It All Offer
INSIDE
$8,463
OCEANVIEW
$8,731
BALCONY
$10,909
SUITE
$14,453
From 8,463
View Trip
18 Day Panama Canal & Inca Discovery with Holland America
Cruise
 (1)

18 Days (17 Nights) Fort Lauderdale to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2024 to Nov 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+2 more), Peru, Chile
Have It All Offer
INSIDE
$4,401
OCEANVIEW
$4,539
BALCONY
$5,460
SUITE
$7,262
From 4,401
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$19,402
SUITE
$28,614
Save 327
From 17,393
View Trip
15 Day South America Passage with Holland America
Cruise
 (1)

15 Days (14 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Dec 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Have It All Offer
INSIDE
$3,664
OCEANVIEW
$3,803
BALCONY
$4,843
SUITE
$6,229
From 3,664
View Trip
7 Day Galapagos Explorer: Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Apr 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,978
From 4,642
View Trip
15 Day Wild Guianas To The Amazon Basin with Seabourn
Cruise

15 Days (14 Nights) Bridgetown to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$21,595
SUITE
$40,999
From 21,595
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 19,700
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Jul 2024 to Mar 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 140
From 6,645
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11 Day Brazilian Brilliance with Oceania Cruises
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$5,124
OCEANVIEW
$5,807
BALCONY
$6,421
SUITE
$8,955
Save 2,036
From 5,124
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17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$18,481
SUITE
$20,115
Save 8,169
From 18,481
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10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,163
From 7,919
View Trip
11 Day Brazilian Rhythms with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2026
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,420
SUITE
$8,955
Save 2,050
From 6,420
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5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 20 March 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$916
OCEANVIEW
$1,045
BALCONY
$1,194
SUITE
$1,540
From 916
View Trip
10 Day Galapagos - Central, West & East Islands aboard the Archipel I with Explore!
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Explore!
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 252
From 10,751
View Trip
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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises South Georgia Island Cruises Spain Cruises Uruguay Cruises

Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Colon Lima Lisbon Malaga Manaus Marseille Papeete Puerto Williams Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo Ushuaia Valparaiso

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Malaga to Malaga Cruises from Marseille to Marseille Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Puerto Williams to Puerto Williams Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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