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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 1,685 expeditions and cruises around South America travelling with the world's leading cruise lines.
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369 Cruises (1,685 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Flash Sale
Exclusive Savings
From
A$17,770
Save 1,307
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (7)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,824
Suite
$18,664
From
A$10,824
Save 1,515
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$9,406
Save 1,922
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,864
Save 2,093
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Feb 2027 to Feb 2028
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
$21,143
Balcony
$23,250
Suite
-
From
A$21,143
Save 2,352
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (7)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,314
Suite
$18,664
From
A$11,314
Save 1,513
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$12,772
Save 2,627
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,738
Save 3,403
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Flash Sale
Exclusive Savings
From
A$15,417
Save 1,258
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$9,316
Oceanview
$9,801
Balcony
$15,388
Suite
-
From
A$9,316
Save 2,204
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2027
Visit: Brazil
Exclusive Savings
Inside
$1,389
Oceanview
$1,548
Balcony
$1,924
Suite
-
From
A$1,389
Per Person
View Trip
21 Day Bridgetown to Rio De Janeiro with Silversea
Cruise
 (1)

21 Days (20 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Nova
Departure: 18 January 2027
Visit: Barbados, Brazil
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$39,788
From
A$39,788
Save 812
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Dec 2027
Visit: Chile, Argentina, Falkland Islands, Uruguay
Princess Standard
Exclusive Savings
Inside
$3,339
Oceanview
-
Balcony
$4,387
Suite
$7,833
From
A$3,339
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 15 March 2027
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,119
Suite
-
From
A$861
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Mar 2027 to Mar 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Fare Saver
Exclusive Savings
Inside
$3,791
Oceanview
$4,088
Balcony
$5,722
Suite
$7,207
From
A$3,791
Per Person
View Trip
15 Day Chilean Fjords – Discovering the Heart of Patagonia (Southbound) with HX Expeditions
Cruise
 (1)

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: HX Expeditions
Ship: MS Fridtjof Nansen
Departure: 17 October 2026
Visit: Chile, Argentina
Inside
-
Oceanview
$9,778
Balcony
$11,435
Suite
$13,877
From
A$9,778
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 January 2027
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,607
Oceanview
$1,854
Balcony
$2,211
Suite
$2,914
From
A$1,607
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Nov 2026 to Dec 2026
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,188
Suite
-
From
A$861
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 17 November 2027
Visit: Argentina, Uruguay, Falkland Islands, Chile
Fare Saver
Exclusive Savings
Inside
$3,000
Oceanview
$3,297
Balcony
$4,584
Suite
$6,762
From
A$3,000
Per Person
View Trip
15 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Feb 2027 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Exclusive Savings
Inside
$3,489
Oceanview
$3,786
Balcony
$5,628
Suite
$6,756
From
A$3,489
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,311
Suite
-
From
A$1,311
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 02 December 2026
Visit: Brazil
Exclusive Savings
Inside
$864
Oceanview
$953
Balcony
$1,102
Suite
$1,428
From
A$864
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,458
Oceanview
$1,706
Balcony
$1,963
Suite
$2,085
From
A$1,458
Per Person
View Trip
15 Day Patagonia & Argentina Cruise with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Cruise Line: Celebrity Cruises
Ships: Celebrity Equinox
Departures: Dec 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,296
Oceanview
$3,247
Balcony
$2,962
Suite
$11,146
From
A$2,962
Save 3,169
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,119
Suite
-
From
A$861
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Dec 2026 to Dec 2027
Visit: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Exclusive Savings
Inside
$3,148
Oceanview
$3,445
Balcony
$4,732
Suite
$6,900
From
A$3,148
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise
 (2)

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Ponant
Ship: Le Boreal
Departure: 18 March 2028
Visit: Argentina, Uruguay, Brazil
Exclusive Savings
Inside
-
Oceanview
$8,946
Balcony
$9,674
Suite
$16,570
From
A$8,946
Save 254
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Nov 2027
Visit: Argentina, Uruguay, Falkland Islands, Chile
Princess Standard
Exclusive Savings
Inside
$2,627
Oceanview
-
Balcony
$3,702
Suite
$4,369
From
A$2,627
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 March 2028
Visit: Argentina
Exclusive Savings
Inside
-
Oceanview
$2,341
Balcony
$2,516
Suite
$4,019
From
A$2,341
Save 59
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,409
Oceanview
$1,656
Balcony
$1,993
Suite
$2,085
From
A$1,409
Per Person
View Trip
Results: 1-30 of 369

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South & Central America Cruises

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Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from England to Holland Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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