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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 1,938 expeditions and cruises around South America traveling with the world's leading cruise lines.
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337 Cruises (1,938 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Nov 2025 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$9,416
Save 351
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jan 2026 to Dec 2026
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$7,173
Save 249
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Nov 2025 to Dec 2026
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$4,661
Save 167
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departure: 01 March 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Brazil, Argentina, Uruguay, Falkland Islands, Chile, Peru
Exclusive Savings
Inside
-
Oceanview
$11,807
Balcony
$13,248
Suite
-
From
US$11,807
Save 688
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departure: 21 February 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Exclusive Savings
Inside
-
Oceanview
$13,229
Balcony
$14,493
Suite
-
From
US$13,229
Save 1,266
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (4)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Jan 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Viking $1,799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,999
Suite
$12,999
From
US$6,999
Save 1,500
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2026 to Dec 2026
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$9,734
Save 334
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Nov 2025 to Dec 2026
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$6,156
Save 1,719
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Nov 2025 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$9,712
Save 543
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Visit: Brazil
Inside
-
Oceanview
-
Balcony
$512
Suite
-
From
US$512
Per Person
View Trip
7 Day Galapagos Express - Central, South & East Islands aboard the Archipel I with Explore Worldwide
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore Worldwide
Departures: Oct 2025 to Dec 2025
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$4,592
Save 668
Per Person
View Trip
10 Day Iconic Wildlife & Sublime Scenery - Plus Machu Picchu (Western Route) with HX Expeditions
Cruise

10 Days (9 Nights) Lima to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Nov 2025 to Mar 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Saving
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
$8,402
Balcony
-
Suite
$10,089
From
US$8,402
Save 1,787
Per Person
View Trip
6 Day Galapagos Encounter: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Nov 2025 to Dec 2026
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$3,235
Save 1,135
Per Person
View Trip
8 Day Galapagos Outer Loop Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Cruise Line: Celebrity Cruises
Ship: Celebrity Flora
Departures: Oct 2025 to Dec 2027
Visit: Galapagos
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,014
From
US$7,014
Save 5,290
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 17 February 2026
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,825
Oceanview
$2,280
Balcony
$2,461
Suite
$3,418
From
US$1,825
Save 54
Per Person
View Trip
9 Day Galapagos - Central & West Islands Aboard the Treasure with Explore Worldwide
Cruise

9 Days (8 Nights) Quito to Quito
Operated By: Explore Worldwide
Departures: Oct 2025 to Dec 2025
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$7,551
Save 1,099
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2025 to Mar 2026
Visit: Brazil
Inside
$918
Oceanview
$1,119
Balcony
$1,363
Suite
$2,205
From
US$918
Per Person
View Trip
18 Day Valparaiso to Buenos Aires with Silversea
Cruise

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 29 January 2028
Visit: Chile, Argentina, Falkland Islands
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$15,000
Suite
-
From
US$15,000
Per Person
View Trip
7 Day Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route) with HX Expeditions
Cruise

7 Days (6 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Dec 2025 to Dec 2026
Visit: Ecuador, Galapagos
Exclusive Saving
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
$6,051
Balcony
-
Suite
$7,924
From
US$6,051
Save 1,583
Per Person
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Belem to Belem
Cruise Line: Seabourn
Ship: Seabourn Venture
Departures: Oct 2025 to Oct 2025
Visit: Brazil
More Moments On Us Offer
Inside
-
Oceanview
-
Balcony
$5,498
Suite
$5,498
From
US$5,498
Per Person
View Trip
11 Day South America with MSC Cruises
Cruise
 (2)

11 Days (10 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 26 December 2025
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$3,181
Oceanview
$3,582
Balcony
$3,982
Suite
$5,200
From
US$3,181
Save 98
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (4)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2025 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Viking $1,799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,999
Suite
$12,999
From
US$6,999
Save 500
Per Person
View Trip
9 Day Island Hopping in the Galapagos with Exodus Adventure Travels
New ReleaseCruise

9 Days (8 Nights) Quito to Quito
Departures: Feb 2026 to Dec 2027
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$5,500
Save 819
Per Person
View Trip
21 Day Bridgetown to Rio De Janeiro with Silversea
Cruise
 (1)

21 Days (20 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Nova
Departure: 18 January 2027
Visit: Barbados, Brazil
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,920
Suite
-
From
US$16,920
Save 1,880
Per Person
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Nov 2025 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$3,928
Save 129
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 08 March 2027
Visit: Chile, Argentina
Fly Free Premium Economy
Fly Free Business Class
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,407
Suite
$25,428
From
US$16,407
Save 17,313
Per Person
View Trip
13 Day Bounty Of Brazil with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 January 2026
Visit: Argentina, Uruguay, Brazil
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,787
Suite
-
From
US$4,787
Save 5,011
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Ponant
Ship: L'Austral
Departure: 16 March 2027
Visit: Argentina, Uruguay, Brazil
Inside
-
Oceanview
-
Balcony
$9,790
Suite
$19,340
From
US$9,790
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Nov 2025 to Dec 2026
Visit: Ecuador
Exclusive Savings
From
US$3,382
Save 1,267
Per Person
View Trip
11 Day South America with MSC Cruises
Cruise
 (2)

11 Days (10 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 December 2025
Visit: Uruguay, Argentina, Brazil
Exclusive Savings
Inside
$3,181
Oceanview
$3,582
Balcony
$3,982
Suite
-
From
US$3,181
Save 98
Per Person
View Trip
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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises French Polynesia Cruises Galapagos Cruises Mexico Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Cruises

Cities

Baltra Island Barcelona Bridgetown Buenos Aires Funchal Lima Lisbon Manaus Montevideo Panama City Quito Rio de Janeiro San Antonio Santiago Santiago Santos Sao Paulo Tahiti Ushuaia Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Quito Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to London Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to Bridgetown Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Venice to Barcelona Cruises from Venice to Rome

Country Routes

Cruises from USA to Portugal Cruises from USA to Germany Cruises from England to Holland Cruises from Germany to England Cruises from Canada to Japan Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to Barbados Cruises from Puerto Rico to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from Brazil to France Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Peru to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from England to Norway Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from USA to Japan Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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