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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 2,126 expeditions and cruises around South America travelling with the world's leading cruise lines.
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428 Cruises (2,126 Departures)
428 Cruises (2,126 Departures)
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Duration
2 Days
141 Days
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Price
$200pp
$133,895pp
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Oct 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$18,556
Save 446
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (2)

18 Days (17 Nights) Buenos Aires to Santiago
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Jan 2027 to Jan 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Balcony
$14,009
Suite
$22,339
From (Per Person)
A$14,009
Save 320
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$6,708
Save 1,350
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,520
Save 1,679
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operator: Travelmarvel
Cruise Line: Holland America
Departures: Feb 2027 to Feb 2028
Trip Styles: Coach, Cruise, Scenic
Visits: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Exclusive Savings
Oceanview
$20,169
Balcony
$22,178
From (Per Person)
A$20,169
Save 2,352
Per Person
View Trip
15 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with Globus
New ReleaseTour + Cruise
 (1)

15 Days Lima to Guayaquil
Operator: Globus
Departures: Jun 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,639
Save 623
Per Person
View Trip
22 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Nazca Lines & the Amazon with Globus
New ReleaseTour + Cruise
 (1)

22 Days Lima to Quito
Operator: Globus
Departures: May 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$19,294
Save 798
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Buenos Aires
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Feb 2029
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Balcony
$12,000
Suite
$18,664
From (Per Person)
A$12,000
Save 1,495
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,823
Save 493
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,127
Save 396
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia +3 more, MSC Musica, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$854
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
16 Day Chile To La: Peru & Mexico with Celebrity Cruises
Cruise
 (1)

16 Days (15 Nights) Valparaiso to Los Angeles
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 24 March 2028
Visits: Chile, Peru, Ecuador, Guatemala, Mexico, USA
Exclusive Savings
Inside
$2,104
Oceanview
$2,225
Balcony
$2,301
Suite
$10,027
From (Per Person)
A$2,104
Save 1,235
Per Person
View Trip
6 Day Ocean Voyage: Callao - Valparaiso with Ponant
Cruise
 (1)

6 Days (5 Nights) Lima to Valparaiso
Operator: Ponant
Ship: L'Austral
Departure: 30 October 2026
Visits: Peru, Chile
Exclusive Savings
Oceanview
$2,233
Balcony
$2,397
Suite
$3,397
From (Per Person)
A$2,233
Save 47
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 16 November 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$951
Balcony
$1,168
Suite
$2,252
From (Per Person)
A$951
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$874
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
27 Day Brazil Intensive Cruise: Sao Paulo, Rio De Janiero & Salvador with Azamara Cruises
Cruise
 (6)

27 Days (26 Nights) Buenos Aires to Bridgetown
Operator: Azamara
Ship: Azamara Quest
Departure: 16 February 2028
Visits: Argentina, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$17,755
Oceanview
$20,235
Balcony
$24,508
Suite
$34,151
From (Per Person)
A$17,755
Save 294
Per Person
View Trip
15 Day Brazil Intensive Cruise: Salvador, Natal & Belem with Azamara Cruises
Cruise
 (6)

15 Days (14 Nights) Rio de Janeiro to Bridgetown
Operator: Azamara
Ship: Azamara Quest
Departure: 28 February 2028
Visits: Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$9,119
Oceanview
$10,746
Balcony
$12,971
Suite
$19,076
From (Per Person)
A$9,119
Save 150
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Operator: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Mar 2027 to Mar 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,792
Oceanview
$4,188
Balcony
$5,920
Suite
$7,900
From (Per Person)
A$3,792
Per Person
View Trip
15 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ships: Celebrity Equinox
Departures: Dec 2026 to Feb 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$2,727
Oceanview
$3,031
Balcony
$3,168
Suite
$8,559
From (Per Person)
A$2,727
Save 3,623
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
$2,164
From (Per Person)
A$1,280
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 02 December 2026
Visits: Brazil
Exclusive Savings
Inside
$834
Oceanview
$943
Balcony
$1,092
Suite
$1,419
From (Per Person)
A$834
Per Person
View Trip
14 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

14 Days (13 Nights) Valparaiso to Buenos Aires
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 20 November 2028
Visits: Chile, Argentina, Uruguay
Exclusive Savings
Inside
$2,293
Oceanview
$2,597
Balcony
$2,734
Suite
$9,323
From (Per Person)
A$2,293
Save 1,408
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,421
Suite
$3,299
From (Per Person)
A$1,421
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Operator: Oceania
Ship: Oceania Sirena
Departure: 19 January 2028
Visits: Peru, Chile
Your World Inclusions
Exclusive Savings
Inside
$7,717
Oceanview
$8,134
Balcony
$9,599
Suite
$13,226
From (Per Person)
A$7,717
Save 2,183
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Dec 2027
Visits: Brazil
Exclusive Savings
Inside
$2,538
Oceanview
$2,755
Balcony
$3,161
Suite
$4,074
From (Per Person)
A$2,538
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visits: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,327
Oceanview
$4,624
Balcony
$5,614
Suite
$8,039
From (Per Person)
A$4,327
Per Person
View Trip
2 Day South America with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Paranagua to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 13 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$464
Suite
$727
From (Per Person)
A$464
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Santos to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,061
From (Per Person)
A$3,061
Per Person
View Trip
11 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise
 (1)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Operator: Silversea
Ship: Silver Nova
Departure: 07 February 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Balcony
$15,043
Suite
$23,716
From (Per Person)
A$15,043
Save 307
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 02 January 2028
Visits: Brazil
Exclusive Savings
Inside
$1,332
Oceanview
$1,461
Balcony
$1,817
Suite
$2,269
From (Per Person)
A$1,332
Per Person
View Trip
Results: 1-30 of 428

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South & Central America Cruises

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Routes

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Country Routes

Cruises from Peru to Argentina Cruises from French Polynesia to Australia Cruises from Australia to England Cruises from Brazil to Ecuador Cruises from USA to Portugal Cruises from Italy to England Cruises from Dominican Republic to Puerto Rico Cruises from England to Holland Cruises from France to Portugal Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Iceland to France Cruises from Brazil to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from Brazil to Portugal Cruises from Puerto Rico to Dominican Republic Cruises from Dominican Republic to USA Cruises from Spain to Turkey Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to Singapore Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to Turkey Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from USA to New Zealand Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Germany to USA Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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