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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 1,809 expeditions and cruises around South America travelling with the world's leading cruise lines.
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391 Cruises (1,809 Departures)
391 Cruises (1,809 Departures)
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Duration
2 Days
141 Days
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$200pp
$133,895pp
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operator: Cosmos
Departures: Nov 2026 to Oct 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$18,473
Save 604
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (2)

18 Days (17 Nights) Buenos Aires to Santiago
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Jan 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Balcony
$12,000
Suite
$18,664
From (Per Person)
A$12,000
Save 1,495
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,871
Save 2,366
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Dec 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,190
Save 1,860
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$11,563
Save 266
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operator: Travelmarvel
Cruise Line: Holland America
Departures: Feb 2027 to Feb 2028
Trip Styles: Coach, Cruise, Scenic
Visits: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Exclusive Savings
Oceanview
$21,143
Balcony
$23,158
From (Per Person)
A$21,143
Save 2,352
Per Person
View Trip
15 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with Globus
New ReleaseTour + Cruise
 (1)

15 Days Lima to Guayaquil
Operator: Globus
Departures: Mar 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,581
Save 623
Per Person
View Trip
22 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Nazca Lines & the Amazon with Globus
New ReleaseTour + Cruise
 (1)

22 Days Lima to Quito
Operator: Globus
Departures: Mar 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$19,236
Save 798
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Buenos Aires
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Feb 2029
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Balcony
$12,000
Suite
$18,664
From (Per Person)
A$12,000
Save 1,495
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,350
Save 2,901
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operator: Cosmos
Departures: Nov 2026 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,119
Save 556
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,290
Oceanview
$1,449
Balcony
$1,825
Suite
-
From (Per Person)
A$1,290
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Valparaiso to Ushuaia
Operator: Azamara
Ship: Azamara Quest
Departure: 24 January 2028
Visits: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
$6,556
Oceanview
$7,691
Balcony
$9,460
Suite
$15,745
From (Per Person)
A$6,556
Save 463
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Holland America
Ship: Nieuw Amsterdam
Departures: Nov 2027 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Exclusive Savings
Inside
$3,148
Oceanview
$3,445
Balcony
$4,732
Suite
$6,910
From (Per Person)
A$3,148
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$861
Oceanview
$951
Balcony
$1,119
Suite
-
From (Per Person)
A$861
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 10 January 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,696
Oceanview
$1,835
Balcony
$2,191
Suite
$2,894
From (Per Person)
A$1,696
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Operator: Oceania
Ship: Oceania Sirena
Departure: 19 January 2028
Visits: Peru, Chile
Your World Inclusions
Exclusive Savings
Inside
$6,669
Oceanview
$7,086
Balcony
$9,017
Suite
$12,877
From (Per Person)
A$6,669
Save 2,151
Per Person
View Trip
14 Day Barbados, French Guiana & Brazil Cruise: Bridgetown, Ile Royale & Rio De Janeiro with Azamara Cruises
Cruise
 (5)

14 Days (13 Nights) Bridgetown to Rio de Janeiro
Operator: Azamara
Ship: Azamara Journey
Departure: 25 January 2027
Visits: Barbados, Trinidad and Tobago, French Guiana, Brazil
Azamara Always Included
Exclusive Savings
Inside
$4,494
Oceanview
$5,062
Balcony
$6,365
Suite
$9,158
From (Per Person)
A$4,494
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to São Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$911
Oceanview
$1,069
Balcony
$1,198
Suite
$1,644
From (Per Person)
A$911
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Divina
Departure: 05 February 2027
Visits: Brazil
Exclusive Savings
Inside
$1,248
Oceanview
$1,416
Balcony
$1,545
Suite
$1,851
From (Per Person)
A$1,248
Per Person
View Trip
9 Day Chile & Peru Cruise: Arica, Pisco & Lima with Azamara Cruises
Cruise
 (5)

9 Days (8 Nights) Santiago to Lima
Operator: Azamara
Ship: Azamara Journey
Departure: 10 March 2027
Visits: Chile, Peru
Exclusive Savings
Inside
$2,768
Oceanview
$3,168
Balcony
$3,829
Suite
-
From (Per Person)
A$2,768
Save 191
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Feb 2027
Visits: Brazil
Exclusive Savings
Inside
$861
Oceanview
$951
Balcony
$1,178
Suite
$1,604
From (Per Person)
A$861
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Operator: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina
Exclusive Savings
Oceanview
$2,731
Balcony
$2,906
Suite
$4,322
From (Per Person)
A$2,731
Save 62
Per Person
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (5)

24 Days (23 Nights) Bridgetown to Buenos Aires
Operator: Azamara
Ship: Azamara Journey
Departure: 25 January 2027
Visits: Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$9,087
Oceanview
$9,655
Balcony
$12,370
Suite
$17,280
From (Per Person)
A$9,087
Per Person
View Trip
27 Day Brazil Intensive Cruise: Sao Paulo, Rio De Janiero & Salvador with Azamara Cruises
Cruise
 (6)

27 Days (26 Nights) Buenos Aires to Bridgetown
Operator: Azamara
Ship: Azamara Quest
Departure: 16 February 2028
Visits: Argentina, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$12,979
Oceanview
$14,775
Balcony
$17,866
Suite
$26,031
From (Per Person)
A$12,979
Save 890
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 11 January 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,676
Oceanview
$1,914
Balcony
$2,191
Suite
$2,894
From (Per Person)
A$1,676
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 06 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,793
Oceanview
$1,971
Balcony
$2,377
Suite
$3,159
From (Per Person)
A$1,793
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$7,476
Oceanview
$8,218
Balcony
$10,842
Suite
$15,049
From (Per Person)
A$7,476
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,399
Oceanview
$1,647
Balcony
$1,983
Suite
$2,696
From (Per Person)
A$1,399
Per Person
View Trip
17 Day Buenos Aires to Valparaiso with Silversea
Cruise
 (1)

17 Days (16 Nights) Buenos Aires to Valparaiso
Operator: Silversea
Ship: Silver Nova
Departure: 17 February 2027
Visits: Argentina, Falkland Islands, Chile
Exclusive Savings
Balcony
$19,698
Suite
$36,162
From (Per Person)
A$19,698
Save 402
Per Person
View Trip
Results: 1-30 of 391

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Routes

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Country Routes

Cruises from Peru to Argentina Cruises from Australia to England Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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