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369 Cruises (1,685 Cruise Departures)
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 02 December 2026
Visit: Brazil
Exclusive Savings
Inside
$864
Oceanview
$953
Balcony
$1,102
Suite
$1,428
From
A$864
Per Person
View Trip
14 Day Argentina, Antarctica & Uruguay Cruise: Ushuaia, Punta Del Este & Montevideo with Azamara Cruises
Cruise
 (5)

14 Days (13 Nights) Ushuaia to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 03 February 2028
Visit: Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Exclusive Savings
Inside
$5,649
Oceanview
$6,688
Balcony
$8,138
Suite
$12,607
From
A$5,649
Save 90
Per Person
View Trip
18 Day Antarctica & Patagonia Expedition with HX Expeditions
Cruise
 (1)

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: HX Expeditions
Ship: MS Fridtjof Nansen
Departure: 26 October 2027
Visit: Chile, Antarctica, Argentina
Inside
-
Oceanview
$18,823
Balcony
$26,133
Suite
$26,133
From
A$18,823
Per Person
View Trip
15 Day Chilean Fjords – Highlights of Patagonia (Northbound) with HX Expeditions
Cruise
 (2)

15 Days (14 Nights) Buenos Aires to Valparaiso
Cruise Line: HX Expeditions
Ship: MS Roald Amundsen
Departure: 01 April 2027
Visit: Argentina, Chile
Inside
-
Oceanview
$10,508
Balcony
$15,453
Suite
$15,452
From
A$10,508
Per Person
View Trip
22 Day Antarctica & Chilean Fjords Cruise: Buenos Aires, Ushuaia & Santiago with Azamara Cruises
Cruise
 (4)

22 Days (21 Nights) Buenos Aires to Santiago
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Azamara Always Included
Exclusive Savings
Inside
$12,113
Oceanview
$12,848
Balcony
$14,318
Suite
$22,707
From
A$12,113
Save 196
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (5)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Exclusive Savings
Inside
$38,419
Oceanview
$41,555
Balcony
$50,286
Suite
$72,797
From
A$38,419
Save 600
Per Person
View Trip
42 Day Miami To Auckland Grand Voyage with Azamara Cruises
Cruise
 (8)

42 Days (41 Nights) Miami to Auckland
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 January 2028
Visit: USA, Aruba, Curacao, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand
Azamara Always Included
Exclusive Savings
Inside
$17,716
Oceanview
$19,117
Balcony
$21,998
Suite
$33,641
From
A$17,716
Save 273
Per Person
View Trip
30 Day Panama Canal & Easter Island Explorer with Seabourn
Cruise
 (1)

30 Days (29 Nights) Miami to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru, Chile
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
$26,125
Balcony
$31,123
Suite
$54,937
From
A$26,125
Save 473
Per Person
View Trip
36 Day World Cruise: Panama Canal Crossing & Polynesia with Seabourn
Cruise
 (1)

36 Days (35 Nights) Miami to Tahiti
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru, Chile, Easter Island, French Polynesia
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
$23,860
Balcony
$27,878
Suite
$58,748
From
A$23,860
Save 438
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 January 2027
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,607
Oceanview
$1,854
Balcony
$2,211
Suite
$2,914
From
A$1,607
Per Person
View Trip
29 Day Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

29 Days (28 Nights) Valparaiso to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 February 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
$27,005
Balcony
$31,611
Suite
-
From
A$27,005
Save 493
Per Person
View Trip
32 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

32 Days (31 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 09 March 2027
Visit: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$6,866
Oceanview
$7,282
Balcony
$10,104
Suite
$13,777
From
A$6,866
Per Person
View Trip
37 Day Caribbean To Cape Horn with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$14,991
Oceanview
$15,466
Balcony
$24,303
Suite
-
From
A$14,991
Save 2,299
Per Person
View Trip
35 Day South America Cruise: Miami, Rio De Janeiro & Buenos Aires with Azamara Cruises
Cruise
 (4)

35 Days (34 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+10 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$16,910
Oceanview
$17,057
Balcony
$20,830
Suite
$32,669
From
A$16,910
Save 259
Per Person
View Trip
59 Day Valparaiso To Miami Grand Voyage with Azamara Cruises
Cruise
 (5)

59 Days (58 Nights) Valparaiso to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+12 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands, USA
Azamara Always Included
Exclusive Savings
Inside
$28,370
Oceanview
$30,682
Balcony
$37,101
Suite
$63,797
From
A$28,370
Save 449
Per Person
View Trip
11 Day A Journey Through Amazonian Mesmerising Wonders to the Caribbean Sunlit Landscapes with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Manaus to San Juan
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 17 February 2028
Visit: Brazil, Trinidad and Tobago, Saint Lucia, Dominica, Saint Martin, Puerto Rico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,363
From
A$10,363
Save 212
Per Person
View Trip
42 Day Antarctic Explorer & the Americas with Viking Cruises
Cruise
 (1)

42 Days (41 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 26 February 2027
Visit: Argentina, Antarctica, Chile, Peru (+4 more), Ecuador, Panama, Mexico, USA
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$48,554
Suite
-
From
A$48,554
Save 2,241
Per Person
View Trip
25 Day South America with MSC Cruises
Cruise
 (1)

25 Days (24 Nights) Buenos Aires to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 04 March 2027
Visit: Argentina, Brazil, Cape Verde, Portugal, Morocco, Spain
Exclusive Savings
Inside
$3,890
Oceanview
$4,395
Balcony
$5,197
Suite
$7,791
From
A$3,890
Per Person
View Trip
12 Day A Journey Through Coastal History & the Heart of the Amazon with Explora Journeys
Cruise
 (1)

12 Days (11 Nights) San Juan to Manaus
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 06 February 2028
Visit: Puerto Rico, Montserrat, Barbados, French Guiana, Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,412
From
A$11,412
Save 233
Per Person
View Trip
30 Day Grand South America Voyage with Holland America
Cruise
 (4)

30 Days (29 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 13 February 2027
Visit: Argentina, Brazil, French Guiana, Barbados (+4 more), Saint Lucia, Saint Kitts and Nevis, Puerto Rico, USA
Advantage Fare
Exclusive Savings
Inside
$10,009
Oceanview
$11,296
Balcony
$20,503
Suite
$41,442
From
A$10,009
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 22 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,744
Suite
-
From
A$14,744
Save 1,551
Per Person
View Trip
34 Day Brazilian & Cape Horn Grand Adventure with Princess
Cruise
 (8)

34 Days (33 Nights) Fort Lauderdale to Santiago
Cruise Line: Princess
Ship: Majestic Princess
Departure: 19 November 2026
Visit: USA, Saint Martin, Saint Lucia, Barbados (+5 more), Brazil, Uruguay, Argentina, Falkland Islands, Chile
Princess Standard
Exclusive Savings
Inside
$5,664
Oceanview
-
Balcony
$7,265
Suite
-
From
A$5,664
Per Person
View Trip
84 Day Miami To Hong Kong Grand Voyage with Azamara Cruises
Cruise
 (8)

84 Days (83 Nights) Miami to Hong Kong
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 January 2028
Visit: USA, Aruba, Curacao, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand, Australia, Indonesia, Malaysia, Philippines, China
Azamara Always Included
Exclusive Savings
Inside
$40,008
Oceanview
$43,938
Balcony
$49,896
Suite
$73,740
From
A$40,008
Save 631
Per Person
View Trip
42 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (4)

42 Days (41 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Advantage Fare
Exclusive Savings
Inside
$15,360
Oceanview
$17,092
Balcony
$30,061
Suite
$59,712
From
A$15,360
Per Person
View Trip
75 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (4)

75 Days (74 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+18 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Peru, Panama, Costa Rica, Colombia, Mexico
Azamara Always Included
Exclusive Savings
Inside
$40,492
Oceanview
$43,491
Balcony
$53,771
Suite
$77,125
From
A$40,492
Save 637
Per Person
View Trip
22 Day From the Caribbean to the Amazon with Viking Cruises
Cruise
 (5)

22 Days (21 Nights) San Juan to San Juan
Cruise Line: Viking Cruises
Ship: Viking Sea
Departure: 15 December 2026
Visit: Puerto Rico, Barbados, French Guiana, Brazil (+4 more), Trinidad and Tobago, Saint Lucia, Antigua and Barbuda, Virgin Islands
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,214
Suite
$25,524
From
A$16,214
Save 1,581
Per Person
View Trip
16 Day Antilles To Andes with Oceania Cruises
Cruise
 (1)

16 Days (15 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia, Panama, Ecuador, Peru
Your World Inclusions
Exclusive Savings
Inside
$5,985
Oceanview
$6,402
Balcony
$10,117
Suite
-
From
A$5,985
Save 2,105
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Lisbon to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 10 November 2027
Visit: Portugal, Brazil
Exclusive Savings
Inside
-
Oceanview
$2,020
Balcony
$2,683
Suite
-
From
A$2,020
Per Person
View Trip
54 Day Ultimate Pole-to-Pole Odyssey with Princess
Cruise
 (8)

54 Days (53 Nights) Buenos Aires to London
Cruise Line: Princess
Ship: Majestic Princess
Departure: 24 January 2028
Visit: Argentina, Chile, Antarctica, Falkland Islands (+6 more), Uruguay, Brazil, Spain, Morocco, England, Norway
Princess Standard
Exclusive Savings
Inside
$8,354
Oceanview
-
Balcony
$12,387
Suite
$15,764
From
A$8,354
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 November 2026
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,168
Suite
-
From
A$861
Per Person
View Trip
Results: 31-60 of 369

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wildlife Cruises

Cities

Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Lima Cruises from Lisbon Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from San Antonio Cruises from Santiago Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valencia Cruises from Valparaiso

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Quito Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Diego to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Vancouver to Los Angeles Cruises from Venice to Athens Cruises from Venice to Barcelona Cruises from Venice to Rome

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from England to Holland Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Ponant Central America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking Central America Cruises Viking South America Cruises

South America Tours

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