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Cruises from Quito to Guayaquil

Are you looking for a cruise from Quito to Guayaquil? April, June and July are the most popular months to cruise between Quito and Guayaquil and there are 165 departures available from four of the world's leading cruise lines.
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12 Cruises (165 Cruise Departures)
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 18 October 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$40,095
From 17,919
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2024 to Mar 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,226
SUITE
$25,245
From 17,226
View Trip
10 Day Galapagos Encounter (Itinerary A) with Exodus Adventure Travels
Cruise

10 Days (9 Nights) Quito to Guayaquil
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 250
From 11,250
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8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,334
From 17,919
View Trip
10 Day Galapagos Encounter (Itinerary C) with Exodus Adventure Travels
Cruise

10 Days (9 Nights) Quito to Guayaquil
Departures: Sep 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 250
From 11,250
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operated By: Tauck
Departures: Apr 2025 to Aug 2025
Trip Styles: Group, Cruise, Family, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
From 12,140
View Trip
10 Day Galapagos Encounter (Itinerary B) with Exodus Adventure Travels
Cruise

10 Days (9 Nights) Quito to Guayaquil
Departures: Aug 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 250
From 11,250
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 05 April 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$21,087
SUITE
$33,165
From 21,087
View Trip
10 Day Galapagos Encounter (Itinerary D) with Exodus Adventure Travels
Cruise

10 Days (9 Nights) Quito to Guayaquil
Departures: Jul 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 250
From 11,250
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Aug 2024 to Mar 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 140
From 6,892
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 01 November 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,730
From 17,919
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Jul 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$21,384
SUITE
$35,739
Save 350
From 21,384
View Trip
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