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Round-trip Cruises from Santos

Are you looking for a cruise starting and ending in Santos? December is the most popular month to join a roundtrip cruise from Santos and we have 24 departures available from one of the world's leading cruise lines.
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8 Cruises (24 Cruise Departures)
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Preziosa, MSC Sinfonia
Departures: Mar 2026 to Mar 2027
Visit: Brazil
Drinks & WiFi Package
Inside
$475
Oceanview
$505
Balcony
$565
Suite
$1,489
From
US$475
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 28 December 2026
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$2,303
Oceanview
$2,359
Balcony
$2,470
Suite
-
From
US$2,303
Save 62
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visit: Brazil, Uruguay, Argentina
Inside
$1,320
Oceanview
$1,368
Balcony
$1,488
Suite
-
From
US$1,320
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Sinfonia
Departures: Mar 2026 to Mar 2027
Visit: Brazil
Inside
$475
Oceanview
$505
Balcony
$565
Suite
$1,465
From
US$475
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Preziosa
Departures: Mar 2026 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Drinks & WiFi Package
Inside
$980
Oceanview
$1,098
Balcony
$1,248
Suite
$1,547
From
US$980
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Nov 2026 to Dec 2026
Visit: Brazil
Inside
$475
Oceanview
$505
Balcony
$575
Suite
-
From
US$475
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 November 2026
Visit: Brazil
Inside
$475
Oceanview
$505
Balcony
$575
Suite
-
From
US$475
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 26 December 2026
Visit: Brazil
Inside
$1,857
Oceanview
$1,864
Balcony
$1,975
Suite
$13,207
From
US$1,857
Per Person
View Trip
Results: 8 results

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