Home > Cruises > South America Cruises > Brazil > Cruises From Santos

Cruises From Santos

Choose from 26 unique expeditions and cruises starting in Santos, and traveling to Copenhagen, Funchal, Genoa, Hamburg, London and more. April is the most popular month to join a cruise from Santos and you can select from 44 departures available from one leading cruise lines.
Filter Results
Departures
Duration
4 Days
25 Days
Countries Visited
End City
Price
$300pp
$2,121pp
Countries
Show More...
Filter Results
26 Cruises (44 Cruise Departures)
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 13 February 2026
Countries Visited: Brazil
Escape To Sea
INSIDE
$928
OCEANVIEW
$1,098
BALCONY
$1,538
SUITE
$1,808
From (per person) 928
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Santos to Paris
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+1 more), France
Escape To Sea
INSIDE
$1,257
OCEANVIEW
$1,497
BALCONY
$1,727
SUITE
$3,257
From (per person) 1,257
View Trip
6 Day MSC Grand Voyages with MSC Cruises
Cruise

6 Days (5 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil
One Way Cruise Offer
INSIDE
$449
OCEANVIEW
-
BALCONY
$709
SUITE
-
From (per person) 449
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 06 February 2026
Countries Visited: Brazil
Escape To Sea
INSIDE
$554
OCEANVIEW
$654
BALCONY
$914
SUITE
$1,074
From (per person) 554
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise

25 Days (24 Nights) Santos to Hamburg
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+5 more), France, Belgium, Denmark, Norway, Germany
Escape To Sea
INSIDE
$1,779
OCEANVIEW
$1,979
BALCONY
$2,279
SUITE
$7,689
From (per person) 1,779
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 26 December 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$1,693
OCEANVIEW
$1,965
BALCONY
$2,175
SUITE
$2,603
From (per person) 1,693
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar, France
Escape To Sea
INSIDE
$1,123
OCEANVIEW
$1,333
BALCONY
$1,693
SUITE
$2,773
From (per person) 1,123
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Jan 2026 to Mar 2026
Countries Visited: Brazil, Uruguay, Argentina
Escape To Sea
INSIDE
$738
OCEANVIEW
$908
BALCONY
$1,068
SUITE
$1,558
From (per person) 738
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 29 December 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$1,685
OCEANVIEW
$1,741
BALCONY
$2,284
SUITE
$2,496
From (per person) 1,685
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar, France (+1 more), Italy
Drinks and Wi-Fi Included
INSIDE
$2,121
OCEANVIEW
$2,271
BALCONY
$2,651
SUITE
$3,781
From (per person) 2,121
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 15 March 2026
Countries Visited: Brazil, Cape Verde, Spain, Morocco (+1 more), Italy
Escape To Sea
INSIDE
$1,153
OCEANVIEW
$1,383
BALCONY
$1,933
SUITE
$2,533
From (per person) 1,153
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Preziosa
Departures: Jan 2026 to Mar 2026
Countries Visited: Brazil
Escape To Sea
INSIDE
$554
OCEANVIEW
$654
BALCONY
$763
SUITE
$1,004
From (per person) 554
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Dec 2025 to Jan 2026
Countries Visited: Brazil
Escape To Sea
INSIDE
$464
OCEANVIEW
$564
BALCONY
$914
SUITE
$984
From (per person) 464
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Dec 2025 to Dec 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$342
OCEANVIEW
$432
BALCONY
$512
SUITE
$772
From (per person) 342
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Copenhagen
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+3 more), France, Belgium, Denmark
Escape To Sea
INSIDE
$1,503
OCEANVIEW
$1,763
BALCONY
$2,023
SUITE
$3,483
From (per person) 1,503
View Trip
13 Day MSC Grand Voyages with MSC Cruises
Cruise

13 Days (12 Nights) Santos to Funchal
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal
Escape To Sea
INSIDE
$944
OCEANVIEW
$1,064
BALCONY
$1,234
SUITE
$2,224
From (per person) 944
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Nov 2025 to Dec 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$538
OCEANVIEW
$648
BALCONY
$738
SUITE
$1,028
From (per person) 538
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 15 March 2026
Countries Visited: Brazil, Cape Verde, Spain, Morocco (+4 more), Italy, Sicily, Malta, Croatia
Escape To Sea
INSIDE
$1,533
OCEANVIEW
$1,833
BALCONY
$2,543
SUITE
$3,323
From (per person) 1,533
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 23 December 2025
Countries Visited: Brazil
Escape To Sea
INSIDE
$711
OCEANVIEW
$861
BALCONY
$991
SUITE
$1,401
From (per person) 711
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 17 January 2026
Countries Visited: Brazil, Uruguay, Argentina
Escape To Sea
INSIDE
$938
OCEANVIEW
$1,028
BALCONY
$1,228
SUITE
$1,788
From (per person) 938
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 13 March 2026
Countries Visited: Brazil
Escape To Sea
INSIDE
$594
OCEANVIEW
$664
BALCONY
$914
SUITE
$1,074
From (per person) 594
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Santos to Santiago De Compostela
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain
Escape To Sea
INSIDE
$1,041
OCEANVIEW
$1,221
BALCONY
$1,391
SUITE
$2,361
From (per person) 1,041
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Dec 2025 to Jan 2026
Countries Visited: Brazil
Escape To Sea
INSIDE
$768
OCEANVIEW
$938
BALCONY
$1,378
SUITE
$1,648
From (per person) 768
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Santos to Oslo
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+4 more), France, Belgium, Denmark, Norway
Escape To Sea
INSIDE
$1,722
OCEANVIEW
$2,100
BALCONY
$2,194
SUITE
-
From (per person) 1,722
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to London
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England
Escape To Sea
INSIDE
$1,245
OCEANVIEW
$1,445
BALCONY
$1,645
SUITE
$3,085
From (per person) 1,245
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 22 February 2026
Countries Visited: Brazil, Argentina, Uruguay
Escape To Sea
INSIDE
$788
OCEANVIEW
$958
BALCONY
$1,118
SUITE
$1,608
From (per person) 788
View Trip
Results: 26 results

No Results found. Try changing your search filters.




Cruises found! Scroll up to view

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

Luxury Cruises Short Break Cruises

Departure Months

November 2025 December 2025 January 2026 February 2026 March 2026 April 2026

Cities

Manaus Rio de Janeiro Santos Sao Paulo

Routes

Buenos Aires to Rio de Janeiro Rio de Janeiro to Buenos Aires Rio de Janeiro to Rio de Janeiro Rio de Janeiro to Barcelona Santos to Santos Sao Paulo to Sao Paulo

Country Routes

Argentina to Brazil Brazil to France Brazil to Portugal Brazil to Spain Brazil to Italy Brazil to Argentina France to Brazil Italy to Brazil Spain to Brazil USA to Brazil

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking Central America Cruises Viking South America Cruises

South America Tours

All South America Tours Amazon Tours Argentina Tours Brazil Tours Chile Tours Colombia Tours Ecuador Tours Galapagos Tours Patagonia Tours Peru Tours

© 2010-2025. Global Journeys. You're viewing our site in US dollars.

    

About Us | View Your Booking | Terms & Conditions | Site Map

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations