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Cruises from Santos

Choose from 25 unique expeditions and cruises starting in Santos, and travelling to Amalfi, Barcelona, Genoa, Maceio, Marseille and more. April is the most popular month to join a cruise from Santos and you can select from 36 departures available from one leading cruise lines.
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25 Cruises (36 Cruise Departures)
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 15 March 2027
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,119
Suite
-
From
A$861
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visit: Brazil
Inside
$252
Oceanview
$301
Balcony
$380
Suite
$658
From
A$252
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil
Exclusive Savings
Inside
$545
Oceanview
$624
Balcony
$822
Suite
$1,100
From
A$545
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$2,070
Oceanview
$2,268
Balcony
$2,743
Suite
-
From
A$2,070
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Nov 2026 to Dec 2026
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,188
Suite
-
From
A$861
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain
Exclusive Savings
Inside
$1,761
Oceanview
$1,959
Balcony
$2,514
Suite
-
From
A$1,761
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Exclusive Savings
Inside
$1,986
Oceanview
$2,243
Balcony
$2,827
Suite
-
From
A$1,986
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Jan 2027 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,528
Oceanview
$1,637
Balcony
$1,736
Suite
$2,241
From
A$1,528
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 28 December 2026
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$3,503
Oceanview
$3,800
Balcony
$4,127
Suite
-
From
A$3,503
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 23 January 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$2,070
Oceanview
$2,308
Balcony
$2,506
Suite
$3,030
From
A$2,070
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,119
Suite
-
From
A$861
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Exclusive Savings
Inside
$2,108
Oceanview
$2,356
Balcony
$2,999
Suite
-
From
A$2,108
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France
Exclusive Savings
Inside
$1,844
Oceanview
$2,062
Balcony
$2,646
Suite
-
From
A$1,844
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

20 Days (19 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil, Spain, Morocco, Gibraltar, Italy
Exclusive Savings
Inside
$2,451
Oceanview
$2,679
Balcony
$3,105
Suite
$5,501
From
A$2,451
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Exclusive Savings
Inside
$2,923
Oceanview
$3,230
Balcony
$4,052
Suite
-
From
A$2,923
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil, Spain, Morocco, Gibraltar
Exclusive Savings
Inside
$2,154
Oceanview
$2,451
Balcony
$2,788
Suite
-
From
A$2,154
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 November 2026
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$970
Balcony
$1,168
Suite
-
From
A$861
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily
Easter Flash Sale
Exclusive Savings
Inside
$2,643
Oceanview
$3,395
Balcony
$3,484
Suite
-
From
A$2,643
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Exclusive Savings
Inside
$3,444
Oceanview
$3,761
Balcony
$4,662
Suite
$17,508
From
A$3,444
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 26 December 2026
Visit: Brazil
Exclusive Savings
Inside
$2,627
Oceanview
$2,716
Balcony
$2,894
Suite
$18,162
From
A$2,627
Per Person
View Trip
7 Day MSC Grand Voyages with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Exclusive Savings
Inside
-
Oceanview
$1,061
Balcony
-
Suite
-
From
A$1,061
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Easter Flash Sale
Exclusive Savings
Inside
$2,814
Oceanview
$3,448
Balcony
$4,250
Suite
-
From
A$2,814
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Jan 2027
Visit: Brazil
Exclusive Savings
Inside
$1,069
Oceanview
$1,198
Balcony
$1,366
Suite
$2,129
From
A$1,069
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco
Easter Flash Sale
Exclusive Savings
Inside
$2,296
Oceanview
$2,791
Balcony
$2,980
Suite
$8,583
From
A$2,296
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Exclusive Savings
Inside
-
Oceanview
$717
Balcony
$855
Suite
$2,697
From
A$717
Per Person
View Trip
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