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Brazil Cruises Starting In April 2026 and 2027

If you're looking at joining a cruise to Brazil in April 2026 or 2027, we have 29 unique cruise itineraries and 115 departures available, operated by five of the world's leading cruise lines departing in April.
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29 Cruises (115 Cruise Departures)
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Maceio to Maceio
Cruise Line: MSC Cruises
Ships: MSC Seaview, MSC Virtuosa
Departures: Mar 2026 to Mar 2027
Visit: Brazil
Inside
$634
Oceanview
$804
Balcony
$1,044
Suite
$1,579
From
US$634
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Visit: Brazil
Drinks & WiFi Package
Inside
$133
Oceanview
$196
Balcony
$238
Suite
$406
From
US$133
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Seaview, MSC Virtuosa
Departures: Mar 2026 to Mar 2027
Visit: Brazil
Exclusive Savings
Inside
$734
Oceanview
$920
Balcony
$1,190
Suite
$1,650
From
US$734
Save 54
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain
Inside
$888
Oceanview
$1,028
Balcony
$1,428
Suite
-
From
US$888
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Splendida
Departures: Apr 2027 to Apr 2027
Visit: Brazil, Spain
Inside
$814
Oceanview
$944
Balcony
$1,314
Suite
-
From
US$814
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France
Inside
$927
Oceanview
$1,071
Balcony
$1,475
Suite
-
From
US$927
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Rio de Janeiro to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France
Inside
-
Oceanview
$1,028
Balcony
-
Suite
-
From
US$1,028
Per Person
View Trip
12 Day MSC Grand Voyages with MSC Cruises
Cruise

12 Days (11 Nights) Maceio to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 09 April 2027
Visit: Brazil, Spain, Morocco
Inside
$965
Oceanview
$1,165
Balcony
$1,455
Suite
$4,272
From
US$965
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Salvador to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 07 April 2027
Visit: Brazil, Spain, Morocco
Inside
$1,054
Oceanview
$1,274
Balcony
$1,474
Suite
$4,972
From
US$1,054
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco
Inside
$1,394
Oceanview
$1,664
Balcony
$1,894
Suite
$5,265
From
US$1,394
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visit: Brazil, Spain, Morocco
Inside
$1,289
Oceanview
$1,549
Balcony
$1,779
Suite
$6,008
From
US$1,289
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Rio de Janeiro to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$950
Oceanview
$1,100
Balcony
$1,410
Suite
-
From
US$950
Per Person
View Trip
13 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

13 Days (12 Nights) Maceio to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 05 April 2027
Visit: Brazil, Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$1,248
Suite
-
From
US$1,248
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Rio de Janeiro to London
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 03 April 2026
Visit: Brazil, Portugal, Spain, England
Inside
-
Oceanview
$1,740
Balcony
$2,187
Suite
$3,215
From
US$1,740
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Rio de Janeiro to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$1,029
Oceanview
$1,179
Balcony
$1,599
Suite
-
From
US$1,029
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$1,004
Oceanview
$1,168
Balcony
$1,561
Suite
-
From
US$1,004
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$1,077
Oceanview
$1,231
Balcony
$1,674
Suite
-
From
US$1,077
Per Person
View Trip
22 Day South America, Canary Islands & Spain with Seabourn
Cruise

22 Days (21 Nights) Rio de Janeiro to Seville
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 06 April 2027
Visit: Brazil, Cape Verde, Spain, Morocco
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,037
From
US$10,037
Save 162
Per Person
View Trip
22 Day Brazil Coast, Cape Verde & Canary Islands Crossing with Seabourn
Cruise

22 Days (21 Nights) Rio de Janeiro to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 04 April 2026
Visit: Brazil, Cape Verde, Spain, Morocco
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,205
Suite
$9,205
From
US$9,205
Save 144
Per Person
View Trip
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Oct 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$9,416
Save 344
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Jul 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Black Friday Sale
Exclusive Savings
From
US$9,872
Save 540
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily
Inside
$1,709
Oceanview
$2,049
Balcony
$2,188
Suite
$7,397
From
US$1,709
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

21 Days (20 Nights) Rio de Janeiro to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Inside
$1,429
Oceanview
$1,659
Balcony
$2,169
Suite
-
From
US$1,429
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Oct 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$12,099
Save 647
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Visit: Brazil, Spain, Gibraltar, France, Italy
Grand Voyages Sale
Inside
$1,170
Oceanview
-
Balcony
$1,767
Suite
$3,242
From
US$1,170
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Inside
$1,501
Oceanview
$1,711
Balcony
$2,230
Suite
-
From
US$1,501
Per Person
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operated By: Globus
Departures: Oct 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$13,862
Save 502
Per Person
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Aug 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$11,454
Save 396
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Santos to Paris
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Visit: Brazil, Portugal, Spain, England, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$4,843
From
US$4,843
Save 134
Per Person
View Trip
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Trip Lengths

1 Month 10 Day 2 Week 3 Week 7 Day

Departure Months

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Cities

Maceio Manaus Rio de Janeiro Salvador Santos Sao Paulo

Routes

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