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Brazil Cruises Starting In April 2027 and 2028

If you're looking at joining a cruise to Brazil in April 2027 or 2028, we have 27 unique cruise itineraries and 72 departures available, operated by six of the world's leading cruise lines departing in April.
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27 Cruises (72 Cruise Departures)
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visit: Brazil
Inside
$79
Oceanview
$119
Balcony
$179
Suite
$379
From
US$79
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$1,909
From
US$1,909
Per Person
View Trip
7 Day MSC Grand Voyages with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$2,769
From
US$2,769
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Splendida
Departures: Apr 2027 to Apr 2027
Visit: Brazil, Spain
Inside
$830
Oceanview
$960
Balcony
$1,310
Suite
-
From
US$830
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain
Inside
$921
Oceanview
$1,041
Balcony
$1,421
Suite
-
From
US$921
Per Person
View Trip
13 Day Wellness Retreat: Rio to Santa Cruz de Tenerife with Scenic
New ReleaseCruise

13 Days (12 Nights) Rio de Janeiro to Tenerife
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 06 April 2028
Visit: Brazil, Spain
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,966
Suite
$10,500
From
US$6,966
Save 1,879
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France
Inside
$937
Oceanview
$1,087
Balcony
$1,487
Suite
-
From
US$937
Per Person
View Trip
12 Day MSC Grand Voyages with MSC Cruises
Cruise

12 Days (11 Nights) Maceio to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 09 April 2027
Visit: Brazil, Spain, Morocco
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$4,395
From
US$4,395
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco
Inside
$1,484
Oceanview
$1,664
Balcony
$1,894
Suite
$5,414
From
US$1,484
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Salvador to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 07 April 2027
Visit: Brazil, Spain, Morocco
Inside
$1,124
Oceanview
$1,274
Balcony
$1,524
Suite
$5,114
From
US$1,124
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visit: Brazil, Spain, Morocco
Inside
$1,289
Oceanview
$1,549
Balcony
$1,779
Suite
-
From
US$1,289
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$1,003
Oceanview
$1,183
Balcony
$1,583
Suite
-
From
US$1,003
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise

16 Days (15 Nights) Rio de Janeiro to Rome
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 03 April 2027
Visit: Brazil, Spain, Corsica, Italy
Inside
-
Oceanview
-
Balcony
$1,774
Suite
-
From
US$1,774
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$1,085
Oceanview
$1,245
Balcony
$1,705
Suite
-
From
US$1,085
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Rio de Janeiro to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$967
Oceanview
$1,117
Balcony
$1,417
Suite
-
From
US$967
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Rio de Janeiro to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy
Inside
$1,033
Oceanview
$1,183
Balcony
$1,613
Suite
-
From
US$1,033
Per Person
View Trip
22 Day South America, Canary Islands & Spain with Seabourn
Cruise

22 Days (21 Nights) Rio de Janeiro to Seville
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 06 April 2027
Visit: Brazil, Cape Verde, Spain, Morocco
Yours to Explore
Inside
-
Oceanview
-
Balcony
-
Suite
$12,399
From
US$12,399
Per Person
View Trip
13 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

13 Days (12 Nights) Maceio to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 05 April 2027
Visit: Brazil, Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$1,244
Suite
-
From
US$1,244
Per Person
View Trip
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Jun 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Black Friday Sale
From
US$9,664
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Jul 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$10,162
Save 250
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Inside
$1,503
Oceanview
$1,723
Balcony
$2,293
Suite
-
From
US$1,503
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

21 Days (20 Nights) Rio de Janeiro to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Inside
$1,429
Oceanview
$1,669
Balcony
$2,219
Suite
-
From
US$1,429
Per Person
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operated By: Globus
Departures: Feb 2027 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
From
US$15,350
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily
Inside
$1,739
Oceanview
$2,049
Balcony
$2,309
Suite
-
From
US$1,739
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Nov 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$12,485
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Rio de Janeiro to Trieste
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 03 April 2027
Visit: Brazil, Spain, Corsica, Italy, Greece
Inside
-
Oceanview
-
Balcony
$2,247
Suite
$3,735
From
US$2,247
Per Person
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Aug 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Sign Up Savings
Today's Deal
Exclusive Savings
From
US$11,220
Save 630
Per Person
View Trip
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