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HX Expeditions

MS Santa Cruz II

MS Santa Cruz II offers guests an exceptional cruising experience, with a cozy guest capacity of a maximum of 90, it creates a relaxed yet classy atmosphere. This environmentally-conscious ship operates carbon-neutrally with a sleek and spacious layout which provides ample opportunities to enjoy your cruise. From savoring mouthwatering meals in the elegant restaurant to engaging with fellow travelers in the Science Center, MS Santa Cruz II truly feels like a home away from home for world explorers.
MS Santa Cruz II offers guests an exceptional cruising experience, with a cozy guest capacity of a maximum of 90, it creates a relaxed yet classy atmosphere. This environmentally-conscious ship operates carbon-neutrally with a sleek and spacious layout which provides ample opportunities to enjoy your cruise. From savoring mouthwatering meals in the elegant restaurant to engaging with fellow travelers in the Science Center, MS Santa Cruz II truly feels like a home away from home for world explorers.
Cruise Departures
Cruise Departures
Ship Type
Ship Type
Expedition Cruise Ship
Passengers
Passengers
90
No. Of Crew
No. Of Crew
50
Launch Date
Launched
2002
Last Refurbished
Refurbished
2021

MS Santa Cruz II Cruises

Choose from 72 vacations cruising on board the MS Santa Cruz II
Galápagos Islands - Nine Of The Best Isles Plus Machu...

16 Days Lima to Quito

Operator: HX Expeditions

From 12,813pp
Save 2,903pp
Galápagos Islands – Iconic Wildlife & Sublime Scenery...

7 Days Quito to Quito

Operator: HX Expeditions

From 6,370pp
Save 1,120pp
Galápagos Islands – Iconic Wildlife & Sublime Scenery...

7 Days Quito to Quito

Operator: HX Expeditions

From 5,810pp
Save 1,680pp
Galápagos Islands – Iconic Wildlife & Sublime Scenery...

12 Days Lima to Quito

Operator: HX Expeditions

From 9,960pp
Save 1,680pp
View all MS Santa Cruz II cruises

Life On Board MS Santa Cruz II

What can you expect when cruising on board MS Santa Cruz II
MS Santa Cruz II
MS Santa Cruz II

Embark on a sustainable and stylish Galápagos adventure aboard the MS Santa Cruz II and embrace the cozy atmosphere for an unforgettable experience. Read more

Unforgettable Expeditions
Unforgettable Expeditions

Explore the Galapagos Islands on an enticing and interesting expedition provided by your committed Expedition Team. Read more

The Science Corner
The Science Corner

The Science Corner includes a glass cabinet, a microscope and a whale vertebrae clone, a perfect learning zone about our science activities.

Gastronomic Delights
Gastronomic Delights

Savour the delightful cuisine and cocktails crafted by our dedicated staff on the MS Santa Cruz II, drawing from delicious local flavours and ingredients. Read more

Adventure is All-Inclusive
Adventure is All-Inclusive

Everything from daily excursions and activities to our onboard Science Centre, meals, gratuities, drinks and more. Read more

Wellness & Workouts
Wellness & Workouts

Enjoy exercise facilities to stay active and find moments of relaxation to rejuvenate both your body and mind. Read more

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Deck Plans

Ocean Deck
EH
Explorer Cabin
FH
Explorer Family Cabin
VH
Voyager Single Cabin
Horizon Deck
EE
Explorer Cabin
Expedition Deck
EP
Explorer Cabin
DS
Darwin suite
Panorama Deck
Sky Deck

Cabins

MS Santa Cruz II Voyager Single Cabin
Voyager Single Cabin
Cabin Type: Oceanview

With comfortable spaces and large picture windows to illuminate the interior spaces and allow guests to take in the views, these cabins offer single bed, and plenty of space for solo travelers. 12sqm.

MS Santa Cruz II Explorer Cabin
Explorer Cabin
Cabin Type: Oceanview

With comfortable spaces and large picture windows to illuminate the interior spaces and allow guests to take in the views, these cabins offer elegant areas to relax after a day of active exploring. The beds convert from double read more to twin upon request. 15sqm.

MS Santa Cruz II Explorer Family Cabin
Explorer Family Cabin
Cabin Type: Oceanview

With comfortable spaces and large picture windows to illuminate the interior spaces and allow guests to take in the views, these cabins offer elegant areas to relax after a day of active exploring. Cabins are equipped with read more twin beds and a sofa bed (ideal for children under 12). 18sqm.

MS Santa Cruz II Darwin suite
Darwin suite
Cabin Type: Suite

Our three Darwin suites on the Panorama deck feature double picture windows, and offers superb comfort and deluxe amenities. Available with a twin or double bed, and if more space is desired, these suites can be interconnected read more with an Explorer cabin. 30sqm.

MS Santa Cruz II Cruise Schedule

All 72 sailings by departure date on board MS Santa Cruz II
Starts
Days
Name
From - To
From
Starts
Friday
29 May 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,659pp
Starts
Wednesday
03 Jun 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,509pp
Starts
Friday
12 Jun 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
14,193pp
Starts
Saturday
13 Jun 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
17 Jun 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
10,043pp
Starts
Friday
26 Jun 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Saturday
27 Jun 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
01 Jul 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Thursday
02 Jul 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
Starts
Thursday
02 Jul 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
15,715pp
Starts
Tuesday
07 Jul 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,490pp
Starts
Tuesday
07 Jul 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
11,565pp
Starts
Friday
10 Jul 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Saturday
11 Jul 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
15 Jul 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Friday
24 Jul 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Saturday
25 Jul 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
29 Jul 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Saturday
08 Aug 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Friday
21 Aug 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Wednesday
26 Aug 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Thursday
27 Aug 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
Starts
Thursday
27 Aug 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
15,715pp
Starts
Tuesday
01 Sep 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,490pp
Starts
Tuesday
01 Sep 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
11,565pp
Starts
Friday
04 Sep 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Saturday
05 Sep 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
09 Sep 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Thursday
10 Sep 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
15,716pp
Starts
Tuesday
15 Sep 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
11,566pp
Starts
Friday
18 Sep 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Wednesday
23 Sep 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Thursday
24 Sep 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
Starts
Thursday
24 Sep 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
15,715pp
Starts
Tuesday
29 Sep 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,490pp
Starts
Tuesday
29 Sep 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
11,565pp
Starts
Friday
02 Oct 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Saturday
03 Oct 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
07 Oct 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Thursday
08 Oct 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
Starts
Thursday
08 Oct 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
15,716pp
Starts
Tuesday
13 Oct 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,490pp
Starts
Tuesday
13 Oct 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
11,566pp
Starts
Friday
16 Oct 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Saturday
17 Oct 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
21 Oct 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Thursday
22 Oct 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
Starts
Thursday
22 Oct 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
15,715pp
Starts
Tuesday
27 Oct 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,490pp
Starts
Tuesday
27 Oct 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
11,565pp
View all MS Santa Cruz II cruises
Cruise Content
Cabin images are sourced from HX Expeditions. These should be treated as indicative only. Cabin inclusions, upholsteries and room layout may differ to the image(s) shown depending on sailing dates.

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