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All South America Cruises

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391 Cruises (1,809 Departures)
391 Cruises (1,809 Departures)
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141 Days
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$133,895pp
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29 Day Best of South America with Amazon & Galápagos Cruises with APT
Tour + Cruise

29 Days Rio de Janeiro to Guayaquil
Operator: APT
Ships: Delfin III
Departures: Jun 2027 to Sep 2028
Trip Styles: Small Group, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Exclusive Savings
Suite
$40,319
From (Per Person)
A$40,319
Save 3,046
Per Person
View Trip
8 Day Galápagos - South & East Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operator: G Adventures
Departures: Sep 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,144
Save 1,855
Per Person
View Trip
20 Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers with Seabourn
Cruise

20 Days (19 Nights) Tahiti to Santiago
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 16 October 2026
Visits: French Polynesia, Pitcairn Islands, Easter Island, Chile
Exclusive Savings
Balcony
$18,742
Suite
$23,250
From (Per Person)
A$18,742
Save 356
Per Person
View Trip
15 Day Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise with Collette
Tour + Cruise

15 Days Lima to Quito
Operator: Collette
Departures: Aug 2026 to Apr 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$12,837
Save 2,974
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Rio de Janeiro to Barcelona
Operator: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visits: Brazil, Spain, Morocco
Exclusive Savings
Inside
$2,180
Oceanview
$2,556
Balcony
$2,982
Suite
-
From (Per Person)
A$2,180
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 22 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,770
Suite
$4,037
From (Per Person)
A$2,770
Per Person
View Trip
24 Day New York to Rio de Janeiro with Crystal Cruises
New ReleaseCruise

24 Days (23 Nights) New York to Rio de Janeiro
Operator: Crystal
Ship: Crystal Serenity
Departure: 12 October 2027
Visits: USA, Bermuda, Antigua and Barbuda, Guadeloupe +7 more, Saint Barthelemy, Puerto Rico, Saint Kitts and Nevis, Saint Lucia, Trinidad and Tobago, French Guiana, Brazil
Exclusive Savings
Oceanview
$13,069
Balcony
$15,789
Suite
$16,754
From (Per Person)
A$13,069
Save 4,031
Per Person
View Trip
43 Day Exploring Greenland, Labrador Coast & Panama Canal with Seabourn
Cruise

43 Days (42 Nights) Reykjavik to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 06 September 2028
Visits: Iceland, Greenland, Canada, Bermuda +6 more, Puerto Rico, Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$43,890
Suite
$63,392
From (Per Person)
A$43,890
Save 808
Per Person
View Trip
72 Day Grand South America Adventure with Oceania Cruises
Cruise

72 Days (71 Nights) Miami to Los Angeles
Operator: Oceania
Ship: Oceania Aurelia
Departure: 27 October 2028
Visits: USA, Virgin Islands, Saint Martin, Saint Barthelemy +20 more, Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Martinique, Saint Lucia, Barbados, Saint Vincent, Grenada, French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Peru, Ecuador, Costa Rica, Guatemala, Mexico
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$46,543
Suite
$50,743
From (Per Person)
A$46,543
Save 3,297
Per Person
View Trip
15 Day San Juan to Rio de Janeiro with Crystal Cruises
New ReleaseCruise

15 Days (14 Nights) San Juan to Rio de Janeiro
Operator: Crystal
Ship: Crystal Serenity
Departure: 21 October 2027
Visits: Puerto Rico, Saint Kitts and Nevis, Saint Lucia, Trinidad and Tobago, French Guiana, Brazil
Exclusive Savings
Oceanview
$9,624
Balcony
$11,642
Suite
$12,520
From (Per Person)
A$9,624
Save 2,676
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,468
Oceanview
$1,577
Balcony
$1,716
Suite
$2,369
From (Per Person)
A$1,468
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Maceio
Operator: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,426
Suite
$2,079
From (Per Person)
A$1,426
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Maceio to Santos
Operator: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$924
Balcony
$953
Suite
$1,518
From (Per Person)
A$924
Per Person
View Trip
7 Day Galápagos Islands - Nature and Wildlife Expedition Cruise (Northern Route) with HX Expeditions
Cruise

7 Days (6 Nights) Quito to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Oct 2026 to Dec 2026
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$9,242
Suite
-
From (Per Person)
A$9,242
Save 270
Per Person
View Trip
15 Day Brazilian Coastal Odyssey with Oceania Cruises
Cruise

15 Days (14 Nights) Bridgetown to Rio de Janeiro
Operator: Oceania
Ship: Oceania Aurelia
Departure: 08 November 2028
Visits: Barbados, Saint Vincent, Grenada, French Guiana, Brazil
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,633
Suite
$10,642
From (Per Person)
A$9,633
Save 2,277
Per Person
View Trip
16 Day Galápagos Islands - Nine of the Best Isles plus Machu Picchu with HX Expeditions
Cruise

16 Days (15 Nights) Lima to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Dec 2026 to Mar 2028
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
Oceanview
$20,282
Suite
$25,107
From (Per Person)
A$20,282
Save 419
Per Person
View Trip
122 Day MSC World Cruise with MSC Cruises
Cruise

122 Days (121 Nights) Marseille to Marseille
Operator: MSC Cruises
Ship: MSC Magnifica
Departure: 06 January 2027
Visits: France, Spain, Gibraltar, Morocco +20 more, Cape Verde, Brazil, Argentina, Falkland Islands, Chile, French Polynesia, Cook Islands, New Zealand, Australia, New Caledonia, Vanuatu, American Samoa, USA, Mexico, Costa Rica, Panama, Dominican Republic, Virgin Islands, Saint Martin, Italy
Exclusive Savings
Inside
-
Oceanview
$38,775
Balcony
$50,754
Suite
-
From (Per Person)
A$38,775
Per Person
View Trip
9 Day Galápagos Islands – In Darwin’s Footsteps (Eastern Route) with HX Expeditions
Cruise

9 Days (8 Nights) Quito to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Oct 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$10,092
Suite
$13,259
From (Per Person)
A$10,092
Save 295
Per Person
View Trip
24 Day Ultimate Chilean Fjords & Antarctica’s Weddell Sea with Scenic
New ReleaseCruise

24 Days (23 Nights) Santiago to Buenos Aires
Operator: Scenic
Ships: Scenic Eclipse I
Departures: Nov 2027 to Nov 2028
Visits: Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$46,931
Suite
$64,375
From (Per Person)
A$46,931
Save 11,070
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operator: Exodus
Departures: Sep 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,056
Save 1,371
Per Person
View Trip
13 Day A Journey From Amazon Adventures To Caribbean Charms with Explora Journeys
Cruise

13 Days (12 Nights) Manaus to San Juan
Operator: Explora Journeys
Ship: Explora I
Departure: 17 February 2027
Visits: Brazil, French Guiana, Saint Vincent, Barbados +4 more, Saint Lucia, Saint Barthelemy, Saint Kitts and Nevis, Puerto Rico
Exclusive Savings
Suite
$13,544
From (Per Person)
A$13,544
Save 276
Per Person
View Trip
14 Day Manaus to Fort Lauderdale with Crystal Cruises
New ReleaseCruise

14 Days (13 Nights) Manaus to Fort Lauderdale
Operator: Crystal
Ship: Crystal Symphony
Departure: 27 January 2027
Visits: Brazil, French Guiana, Barbados, Antigua and Barbuda, Virgin Islands, USA
Exclusive Savings
Oceanview
$11,045
Balcony
$13,482
Suite
$15,432
From (Per Person)
A$11,045
Save 255
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galápagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operator: Globus
Departures: Nov 2026 to Nov 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,420
Save 466
Per Person
View Trip
10 Day Classic Galapagos: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,136
Save 2,973
Per Person
View Trip
17 Day Absolute Galapagos (Grand Daphne) with Intrepid Travel
Cruise

17 Days (16 Nights) Quito to Quito
Operator: Intrepid
Departure: 18 August 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,117
Save 4,359
Per Person
View Trip
13 Day Fort Lauderdale to Manaus (Amazon) with Crystal Cruises
New ReleaseCruise

13 Days (12 Nights) Fort Lauderdale to Manaus
Operator: Crystal
Ship: Crystal Symphony
Departure: 15 January 2027
Visits: USA, Saint Barthelemy, Martinique, Saint Vincent, Trinidad and Tobago, Brazil
Exclusive Savings
Oceanview
$10,265
Balcony
$12,507
Suite
$14,360
From (Per Person)
A$10,265
Save 235
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 27 December 2026
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$3,245
Oceanview
$3,622
Balcony
$3,810
Suite
$4,839
From (Per Person)
A$3,245
Per Person
View Trip
32 Day Antarctic Voyage with Galápagos and Peru with APT
New ReleaseTour + Cruise

32 Days Quito to Buenos Aires
Operator: APT
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 31 January 2028
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos, Peru, Argentina, Antarctica
Exclusive Savings
Balcony
$48,533
Suite
$51,473
From (Per Person)
A$48,533
Save 3,262
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Palermo to Buenos Aires
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 12 November 2026
Visits: Sicily, Malta, Spain, Gibraltar +4 more, Morocco, Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,929
From (Per Person)
A$6,929
Per Person
View Trip
116 Day MSC World Cruise with MSC Cruises
Cruise

116 Days (115 Nights) Marseille to Marseille
Operator: MSC Cruises
Ship: MSC Magnifica
Departure: 06 January 2028
Visits: France, Spain, Turks and Caicos Islands, Bahamas +22 more, Panama, Ecuador, Peru, Chile, French Polynesia, Tonga, New Caledonia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Cambodia, Singapore, Malaysia, Sri Lanka, India, United Arab Emirates, Oman, Jordan, Egypt, Italy
Exclusive Savings
Inside
$33,398
Oceanview
$37,477
Balcony
$49,703
Suite
$125,382
From (Per Person)
A$33,398
Per Person
View Trip
Results: 271-300 of 391

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wildlife Cruises

Cities

Cruises from Baltra Island Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Lima Cruises from Lisbon Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from San Antonio Cruises from Santiago Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valencia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Reykjavik to New York Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Diego to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Ushuaia to Ushuaia Cruises from Vancouver to Los Angeles Cruises from Venice to Athens Cruises from Venice to Barcelona Cruises from Venice to Rome

Country Routes

Cruises from Peru to Argentina Cruises from Australia to England Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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