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347 Cruises (2,121 Cruise Departures)
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Rio de Janeiro to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Bonus Onboard Credit
Inside
$1,884
Oceanview
$2,223
Balcony
$2,369
Suite
-
From
US$1,884
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Genoa to Santos
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 04 November 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,337
Oceanview
$2,007
Balcony
$2,971
Suite
$3,679
From
US$1,337
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Amalfi to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 13 November 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,859
Oceanview
-
Balcony
-
Suite
$4,906
From
US$1,859
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Genoa to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,429
Oceanview
$1,709
Balcony
$1,969
Suite
$5,484
From
US$1,429
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Bonus Onboard Credit
Inside
$1,949
Oceanview
$2,209
Balcony
$2,473
Suite
$8,438
From
US$1,949
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise

26 Days (25 Nights) Rome to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 22 October 2027
Visit: Italy, Greece, Turkey, France, Spain, Brazil
Bonus Onboard Credit
Inside
$2,169
Oceanview
$2,464
Balcony
$2,882
Suite
$4,705
From
US$2,169
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Amalfi to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 28 October 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,599
Oceanview
$1,929
Balcony
$2,197
Suite
$6,252
From
US$1,599
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Rome to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 October 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,487
Oceanview
$1,807
Balcony
$2,137
Suite
$3,398
From
US$1,487
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Palermo to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 12 November 2027
Visit: Sicily, Italy, France, Spain, Brazil
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,379
From
US$8,379
Save 240
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Rome to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 16 November 2027
Visit: Italy, Spain, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$1,869
Oceanview
$2,265
Balcony
$2,469
Suite
$3,846
From
US$1,869
Per Person
View Trip
36 Day World Cruise: Panama Canal Crossing & Polynesia with Seabourn
Cruise
 (1)

36 Days (35 Nights) Miami to Tahiti
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru, Chile, Easter Island, French Polynesia
Explore More
Exclusive Savings
Inside
-
Oceanview
$16,821
Balcony
$18,903
Suite
$37,646
From
US$16,821
Save 263
Per Person
View Trip
63 Day Atolls To Eastern Empires with Oceania Cruises
Cruise

63 Days (62 Nights) Tahiti to Tokyo
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 08 February 2027
Visit: French Polynesia, Cook Islands, Niue, Tonga (+11 more), Fiji, Vanuatu, New Caledonia, Australia, Indonesia, Singapore, Thailand, Vietnam, China, South Korea, Japan
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$30,976
Suite
-
From
US$30,976
Save 32,622
Per Person
View Trip
20 Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers with Seabourn
Cruise

20 Days (19 Nights) Tahiti to Santiago
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 16 October 2026
Visit: French Polynesia, Pitcairn Islands, Chile
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,197
Suite
$19,195
From
US$14,197
Save 252
Per Person
View Trip
37 Day Grand World Voyage with Holland America
Cruise

37 Days (36 Nights) Fort Lauderdale to Sydney
Cruise Line: Holland America
Ship: Volendam
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru (+8 more), Chile, Easter Island, Pitcairn Islands, French Polynesia, Samoa, Fiji, New Caledonia, Australia
Advantage Fare
Exclusive Savings
Inside
$8,533
Oceanview
$9,415
Balcony
$15,981
Suite
-
From
US$8,533
Save 131
Per Person
View Trip
37 Day San Antonio To Hamburg with Cunard
Cruise

37 Days (36 Nights) Santiago to Hamburg
Cruise Line: Cunard
Ship: Queen Anne
Departure: 28 February 2027
Visit: Chile, Peru, Ecuador, Panama (+6 more), Aruba, USA, Portugal, England, Belgium, Germany
Inside
$5,929
Oceanview
$8,128
Balcony
$9,247
Suite
$20,038
From
US$5,929
Per Person
View Trip
32 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (2)

32 Days (31 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2026 to Nov 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+5 more), Peru, Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,959
Oceanview
$4,069
Balcony
$5,599
Suite
$8,245
From
US$3,959
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Santiago
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 06 November 2026
Visit: USA, Mexico, Panama, Ecuador, Peru, Chile
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$9,995
Suite
$14,995
From
US$9,995
Per Person
View Trip
32 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (2)

32 Days (31 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2027 to Mar 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,294
Oceanview
$4,494
Balcony
$6,397
Suite
$9,092
From
US$4,294
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 22 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
Flights Included
Inside
-
Oceanview
-
Balcony
$10,995
Suite
$16,995
From
US$10,995
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (4)

20 Days (19 Nights) Miami to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$6,711
Oceanview
$7,594
Balcony
$9,223
Suite
$13,210
From
US$6,711
Save 148
Per Person
View Trip
20 Day Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Azamara Cruises
Cruise
 (3)

20 Days (19 Nights) Santiago to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 March 2027
Visit: Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Exclusive Savings
Inside
$6,145
Oceanview
$6,892
Balcony
$7,697
Suite
$12,751
From
US$6,145
Save 134
Per Person
View Trip
17 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (2)

17 Days (16 Nights) Fort Lauderdale to Santiago
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2026 to Nov 2027
Visit: USA, Cayman Islands, Panama, Ecuador, Peru, Chile
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,059
Oceanview
$2,159
Balcony
$3,059
Suite
$4,692
From
US$2,059
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,530
Suite
$15,860
From
US$12,530
Save 5,370
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visit: Peru, Ecuador, Costa Rica, Panama (+4 more), Honduras, Belize, Mexico, USA
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,677
Suite
$13,755
From
US$12,677
Save 19,121
Per Person
View Trip
13 Day Miami, Fl to Lima (Callao) with Silversea
Cruise

13 Days (12 Nights) Miami to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 January 2028
Visit: USA, Mexico, Costa Rica, Panama, Ecuador, Peru
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,640
Suite
$14,440
From
US$8,640
Save 2,160
Per Person
View Trip
41 Day Amazon & Tropical Isles with Oceania Cruises
Cruise
 (1)

41 Days (40 Nights) Lisbon to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 09 November 2026
Visit: Portugal, Spain, Puerto Rico, Bahamas (+9 more), USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$9,706
Oceanview
$10,822
Balcony
$15,866
Suite
$21,152
From
US$9,706
Save 10,092
Per Person
View Trip
30 Day Southampton To Rio De Janeiro with Cunard
Cruise

30 Days (29 Nights) London to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Anne
Departure: 10 January 2027
Visit: England, Bermuda, USA, Turks and Caicos Islands, Barbados, Brazil
Inside
$4,289
Oceanview
$5,909
Balcony
$6,347
Suite
$14,891
From
US$4,289
Per Person
View Trip
71 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

71 Days (70 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+12 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Barbados, Saint Lucia, Saint Kitts and Nevis, Puerto Rico
Advantage Fare
Exclusive Savings
Inside
$15,385
Oceanview
$17,149
Balcony
$30,477
Suite
$60,857
From
US$15,385
Per Person
View Trip
59 Day Valparaiso To Miami Grand Voyage with Azamara Cruises
Cruise
 (4)

59 Days (58 Nights) Valparaiso to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+12 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands, USA
Azamara Always Included
Exclusive Savings
Inside
$19,740
Oceanview
$21,874
Balcony
$26,433
Suite
$40,294
From
US$19,740
Save 469
Per Person
View Trip
55 Day Epic Antarctic & Amazon with Oceania Cruises
Cruise
 (1)

55 Days (54 Nights) Valparaiso to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands (+6 more), Uruguay, Brazil, Barbados, Antigua and Barbuda, Virgin Islands, USA
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$15,043
Oceanview
$16,110
Balcony
$21,203
Suite
$31,533
From
US$15,043
Save 15,655
Per Person
View Trip
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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises French Polynesia Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wellness Cruises Wildlife Cruises

Cities

Cruises from Baltra Island Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Lima Cruises from Lisbon Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Montevideo Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from San Antonio Cruises from San Cristobal Island Cruises from Santiago Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Tahiti Cruises from Valencia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Cristobal Island to San Cristobal Island Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Venice to Athens Cruises from Venice to Barcelona Cruises from Venice to Rome

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from Germany to England Cruises from Canada to Japan Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from England to Norway Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from USA to Japan Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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