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All South America Cruises

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428 Cruises (2,126 Departures)
428 Cruises (2,126 Departures)
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141 Days
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15 Day Ecuador: Natural Wonders & Ancient Cultures with Galápagos Cruise with Globus
New ReleaseTour + Cruise

15 Days Quito to Guayaquil
Operator: Globus
Departures: Nov 2026 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,291
Save 570
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) London to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Meraviglia
Departure: 06 November 2027
Visits: England, Spain, Portugal, Brazil
Exclusive Savings
Inside
$1,919
Oceanview
$2,553
Balcony
$3,186
Suite
$6,312
From (Per Person)
A$1,919
Per Person
View Trip
68 Day Grand World Voyage with Holland America
Cruise

68 Days (67 Nights) Fort Lauderdale to Sydney
Operator: Holland America
Ship: Volendam
Departure: 04 January 2028
Visits: USA, Barbados, French Guiana, Brazil +9 more, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Pitcairn Islands, French Polynesia, New Zealand, Australia
Advantage Fare
Exclusive Savings
Inside
$25,219
Oceanview
$27,843
Balcony
$48,336
Suite
-
From (Per Person)
A$25,219
Per Person
View Trip
9 Day Cruising the Galapagos Islands with Tauck
Tour + Cruise

9 Days Guayaquil to Guayaquil
Operator: Tauck
Departures: Nov 2026 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
Complimentary Hotel Night
From (Per Person)
A$14,345
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operator: Silversea
Ship: Silver Origin
Departures: Oct 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Balcony
$17,934
Suite
$23,814
From (Per Person)
A$17,934
Save 3,938
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Barcelona to Buenos Aires
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 18 November 2027
Visits: Spain, Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$2,929
Oceanview
$3,404
Balcony
$3,641
Suite
$5,978
From (Per Person)
A$2,929
Per Person
View Trip
24 Day Buenos Aires to Dakar with Silversea
Cruise

24 Days (23 Nights) Buenos Aires to Dakar
Operator: Silversea
Ship: Silver Endeavour
Departure: 25 March 2027
Visits: Argentina, Uruguay, Brazil, Australia +4 more, Scotland, Sierra Leone, Guinea-Bissau, Senegal
Exclusive Savings
Balcony
$22,981
Suite
$31,654
From (Per Person)
A$22,981
Save 3,969
Per Person
View Trip
13 Day Fort Lauderdale to Manaus (Amazon) with Crystal Cruises
New ReleaseCruise

13 Days (12 Nights) Fort Lauderdale to Manaus
Operator: Crystal
Ship: Crystal Symphony
Departure: 15 January 2027
Visits: USA, Saint Barthelemy, Martinique, Saint Vincent, Trinidad and Tobago, Brazil
Exclusive Savings
Oceanview
$10,265
Balcony
$12,507
Suite
$14,360
From (Per Person)
A$10,265
Save 235
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ships: MSC Meraviglia, MSC Seaview
Departures: Jan 2027 to Mar 2028
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,518
Oceanview
$1,716
Balcony
$2,181
Suite
$3,520
From (Per Person)
A$1,518
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Rome to Buenos Aires
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 16 November 2027
Visits: Italy, Spain, Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$3,107
Oceanview
$3,780
Balcony
$4,077
Suite
$6,216
From (Per Person)
A$3,107
Per Person
View Trip
38 Day Grand World Voyage with Holland America
Cruise

38 Days (37 Nights) Fort Lauderdale to Santiago
Operator: Holland America
Ship: Volendam
Departure: 04 January 2028
Visits: USA, Barbados, French Guiana, Brazil +5 more, Uruguay, Argentina, Falkland Islands, Antarctica, Chile
Advantage Fare
Exclusive Savings
Inside
$13,923
Oceanview
$15,259
Balcony
-
Suite
-
From (Per Person)
A$13,923
Per Person
View Trip
7 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operator: Globus
Departures: Oct 2026 to Mar 2028
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,031
Save 276
Per Person
View Trip
17 Day Complete Galápagos - Eden with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,123
Save 3,616
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Salvador to Salvador
Operator: MSC Cruises
Ship: MSC Virtuosa
Departure: 21 March 2028
Visits: Brazil
Exclusive Savings
Inside
$1,733
Oceanview
$1,941
Balcony
$2,446
Suite
$4,009
From (Per Person)
A$1,733
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Santiago
Operator: Viking
Ship: Viking Octantis
Departure: 06 November 2026
Visits: USA, Mexico, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$18,664
Suite
$21,604
From (Per Person)
A$18,664
Save 1,631
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ships: MSC Meraviglia, MSC Seaview
Departures: Dec 2026 to Mar 2028
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,458
Oceanview
$1,656
Balcony
$2,112
Suite
$3,441
From (Per Person)
A$1,458
Per Person
View Trip
42 Day Antarctic Explorer & the Americas with Viking Cruises
Cruise

42 Days (41 Nights) Buenos Aires to Fort Lauderdale
Operator: Viking
Ship: Viking Polaris
Departure: 26 February 2027
Visits: Argentina, Antarctica, Chile, Peru +4 more, Ecuador, Panama, Mexico, USA
Exclusive Savings
Balcony
$51,249
Suite
-
From (Per Person)
A$51,249
Save 1,046
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Rio de Janeiro to Florence
Operator: MSC Cruises
Ship: MSC Virtuosa
Departure: 26 March 2028
Visits: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Exclusive Savings
Inside
$3,023
Oceanview
$3,607
Balcony
$4,330
Suite
-
From (Per Person)
A$3,023
Per Person
View Trip
29 Day Ultimate Antarctica & the Fjords of Southern Chile with Scenic
New ReleaseCruise

29 Days (28 Nights) Buenos Aires to Buenos Aires
Operator: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Feb 2029
Visits: Argentina, Antarctica, Chile, Uruguay
Complimentary 30min Heli Flight
Exclusive Savings
Balcony
$46,754
Suite
$68,098
From (Per Person)
A$46,754
Save 19,033
Per Person
View Trip
13 Day Fort Lauderdale to Manaus with Crystal Cruises
Cruise

13 Days (12 Nights) Fort Lauderdale to Manaus
Operator: Crystal
Ship: Crystal Serenity
Departure: 18 January 2028
Visits: USA, Virgin Islands, Guadeloupe, Saint Lucia, Trinidad and Tobago, Brazil
Exclusive Savings
Oceanview
$9,950
Balcony
$11,705
Suite
$12,495
From (Per Person)
A$9,950
Save 1,250
Per Person
View Trip
7 Day Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route) with HX Expeditions
Cruise

7 Days (6 Nights) Quito to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Oct 2026 to Dec 2026
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$8,462
Suite
-
From (Per Person)
A$8,462
Save 267
Per Person
View Trip
17 Day Trinidad To Rio: South American Expedition with Seabourn
Cruise

17 Days (16 Nights) Bridgetown to Rio de Janeiro
Operator: Seabourn
Ship: Seabourn Venture
Departures: Oct 2027 to Oct 2028
Visits: Barbados, Trinidad and Tobago, French Guiana, Brazil
Exclusive Savings
Balcony
-
Suite
$14,916
From (Per Person)
A$14,916
Save 283
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: G Adventures
Departures: Nov 2026 to Dec 2028
Visits: Galapagos
Exclusive Savings
From (Per Person)
A$9,615
Save 1,534
Per Person
View Trip
10 Day Classic Galapagos: Central Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$9,631
Save 1,876
Per Person
View Trip
12 Day Puerto Williams to Valparaiso with Silversea
Cruise

12 Days (11 Nights) Puerto Williams to Valparaiso
Operator: Silversea
Ship: Silver Cloud
Departure: 27 February 2027
Visits: Chile, Argentina
Exclusive Savings
Oceanview
$11,123
Balcony
$16,709
Suite
$29,792
From (Per Person)
A$11,123
Save 227
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Sao Paulo to Salvador
Operator: MSC Cruises
Ship: MSC Virtuosa
Departure: 05 December 2026
Visits: Brazil
Exclusive Savings
Inside
$825
Oceanview
$983
Balcony
$1,082
Suite
$1,676
From (Per Person)
A$825
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ship: MSC Meraviglia
Departure: 30 December 2027
Visits: Argentina, Uruguay, Brazil
Exclusive Savings
Inside
$2,488
Oceanview
$2,755
Balcony
$3,221
Suite
$4,975
From (Per Person)
A$2,488
Per Person
View Trip
11 Day Brazil To Rio De La Plata with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Operator: Oceania
Ship: Oceania Aurelia
Departure: 22 November 2028
Visits: Brazil, Uruguay, Argentina
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,941
Suite
$7,746
From (Per Person)
A$6,941
Save 2,179
Per Person
View Trip
29 Day Legendary Amazon Explorer with Holland America
Cruise

29 Days (28 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Zuiderdam
Departure: 06 January 2028
Visits: USA, Bahamas, Saint Martin, Martinique +7 more, Trinidad and Tobago, Brazil, French Guiana, Barbados, Dominica, Saint Kitts and Nevis, Puerto Rico
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$9,029
Oceanview
$9,920
Balcony
$15,701
Suite
-
From (Per Person)
A$9,029
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Buenos Aires to Trieste
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 31 March 2027
Visits: Argentina, Brazil, Spain, Corsica, Italy, Greece
Exclusive Savings
Inside
$3,225
Oceanview
$3,829
Balcony
$4,176
Suite
$6,572
From (Per Person)
A$3,225
Per Person
View Trip
Results: 301-330 of 428

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Cape Verde Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Patagonia Cruises Peru Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wildlife Cruises

Cities

Cruises from Baltra Island Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Itajai Cruises from Lima Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Rome Cruises from Fort Lauderdale to San Juan Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Itajai to Itajai Cruises from Lima to Guayaquil Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Athens Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to Miami Cruises from New York to Fort Lauderdale Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Lisbon Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Diego to Fort Lauderdale Cruises from San Juan to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Valparaiso to Buenos Aires

Country Routes

Cruises from Peru to Argentina Cruises from French Polynesia to Australia Cruises from Australia to England Cruises from Brazil to Ecuador Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Dominican Republic to Puerto Rico Cruises from England to Holland Cruises from France to Portugal Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Iceland to France Cruises from Brazil to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Puerto Rico to Dominican Republic Cruises from Dominican Republic to USA Cruises from Spain to Turkey Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Portugal to Greece Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to Singapore Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to Turkey Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from USA to New Zealand Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Germany to USA Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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