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All South America Cruises

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428 Cruises (2,126 Departures)
428 Cruises (2,126 Departures)
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141 Days
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10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Splendida
Departures: Jan 2027 to Feb 2028
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,899
Oceanview
$2,186
Balcony
$2,582
Suite
$3,562
From (Per Person)
A$1,899
Per Person
View Trip
11 Day Glaciers & Fjords of Southern Patagonia with Aurora Expeditions
New ReleaseCruise

11 Days (10 Nights) Ushuaia to Punta Arenas
Operator: Aurora Expeditions
Ship: Douglas Mawson
Departure: 28 March 2027
Visits: Argentina, Chile
Exclusive Savings
Oceanview
$18,038
Balcony
$19,064
Suite
$28,748
From (Per Person)
A$18,038
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visits: Peru, Ecuador, Costa Rica, Panama +4 more, Honduras, Belize, Mexico, USA
Exclusive Savings
Balcony
$17,590
Suite
$18,232
From (Per Person)
A$17,590
Save 7,800
Per Person
View Trip
9 Day A Journey Through Penguin Shores & Patagonian Legends with Explora Journeys
Cruise

9 Days (8 Nights) Buenos Aires to Ushuaia
Operator: Explora Journeys
Ship: Explora I
Departure: 11 January 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Suite
$6,483
From (Per Person)
A$6,483
Save 132
Per Person
View Trip
29 Day Best of South America with Amazon & Galápagos Cruises with APT
Tour + Cruise

29 Days Rio de Janeiro to Guayaquil
Operator: APT
Ships: Delfin III
Departures: Jun 2027 to Sep 2028
Trip Styles: Small Group, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Exclusive Savings
Suite
$40,319
From (Per Person)
A$40,319
Save 3,046
Per Person
View Trip
16 Day Pan-american Discovery with Oceania Cruises
Cruise

16 Days (15 Nights) Lima to Los Angeles
Operator: Oceania
Ship: Oceania Aurelia
Departure: 22 December 2028
Visits: Peru, Ecuador, Costa Rica, Guatemala, Mexico, USA
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,892
Suite
$11,046
From (Per Person)
A$9,892
Save 2,288
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Maceio
Operator: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
$980
Oceanview
$1,178
Balcony
$1,327
Suite
$2,079
From (Per Person)
A$980
Per Person
View Trip
17 Day Panama Canal & Historic Coasts Of South America with Seabourn
Cruise

17 Days (16 Nights) Oranjestad to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 02 October 2028
Visits: Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$15,515
Suite
$21,101
From (Per Person)
A$15,515
Save 283
Per Person
View Trip
19 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Amazon with Globus
New ReleaseTour + Cruise

19 Days Lima to Quito
Operator: Globus
Departures: Jun 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$17,645
Save 748
Per Person
View Trip
26 Day Best of South America with Galápagos Cruise with APT
New ReleaseTour + Cruise

26 Days Rio de Janeiro to Guayaquil
Operator: APT
Departures: Sep 2027 to Nov 2028
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$33,435
Save 2,118
Per Person
View Trip
25 Day An Extended Journey into Island Elegance & Mysteries of the Amazon with Explora Journeys
Cruise

25 Days (24 Nights) San Juan to San Juan
Operator: Explora Journeys
Ship: Explora I
Departure: 05 February 2027
Visits: Puerto Rico, Saint Barthelemy, Martinique, Barbados +6 more, Trinidad and Tobago, Brazil, French Guiana, Saint Vincent, Saint Lucia, Saint Kitts and Nevis
Exclusive Savings
Suite
$26,813
From (Per Person)
A$26,813
Save 547
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil or Lima to Quito
Operator: Tauck
Cruise Line: Silversea
Ships: Silver Origin
Departures: Oct 2026 to May 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Complimentary Hotel Night
Balcony
$51,064
Suite
$69,389
From (Per Person)
A$25,532
Per Person
View Trip
21 Day Valparaiso to Puerto Williams with Silversea
Cruise

21 Days (20 Nights) Valparaiso to Santiago
Operator: Silversea
Ship: Silver Cloud
Departure: 15 November 2027
Visits: Chile, Argentina, Antarctica
Exclusive Savings
Oceanview
-
Balcony
$45,374
Suite
$60,319
From (Per Person)
A$45,374
Save 926
Per Person
View Trip
131 Day Grand World Voyage with Holland America
Cruise

131 Days (130 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Volendam
Departure: 05 January 2027
Visits: USA, Panama, Ecuador, Peru +29 more, Chile, Pitcairn Islands, French Polynesia, Samoa, Fiji, New Caledonia, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Mauritius, Reunion, South Africa, Namibia, Gambia, Senegal, Cape Verde, Spain, Morocco, Portugal, France, Holland, Norway, Denmark, England, Puerto Rico
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$40,929
Oceanview
$45,582
Balcony
$85,528
Suite
$346,789
From (Per Person)
A$40,929
Per Person
View Trip
26 Day Roundtrip Fort Lauderdale with Crystal Cruises
Cruise

26 Days (25 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Crystal
Ship: Crystal Serenity
Departure: 18 January 2028
Visits: USA, Virgin Islands, Guadeloupe, Saint Lucia +6 more, Trinidad and Tobago, Brazil, French Guiana, Barbados, Dominica, Saint Barthelemy
Exclusive Savings
Oceanview
$17,430
Balcony
$20,325
Suite
$20,940
From (Per Person)
A$17,430
Save 3,570
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 22 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,859
Suite
$3,998
From (Per Person)
A$2,859
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Meraviglia, MSC Seaview
Departures: Jan 2027 to Mar 2028
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,439
Oceanview
$1,716
Balcony
$2,151
Suite
$2,894
From (Per Person)
A$1,439
Per Person
View Trip
7 Day Galápagos Land & Sea - Central & South Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,630
Save 1,129
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ship: MSC Meraviglia
Departure: 23 December 2027
Visits: Argentina, Uruguay, Brazil
Exclusive Savings
Inside
$1,825
Oceanview
$2,072
Balcony
$2,528
Suite
$4,213
From (Per Person)
A$1,825
Per Person
View Trip
13 Day Peru Splendors with Galápagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operator: Globus
Departures: Mar 2027 to Dec 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$12,156
Save 380
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Genoa to Buenos Aires
Operator: MSC Cruises
Ship: MSC Splendida
Departure: 15 November 2027
Visits: Italy, Spain, Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$3,286
Oceanview
$3,988
Balcony
$4,285
Suite
$6,553
From (Per Person)
A$3,286
Per Person
View Trip
9 Day The Poets' Passage with Regent Seven Seas
Cruise

9 Days (8 Nights) Valparaiso to Lima
Operator: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 18 February 2029
Visits: Chile, Peru
Exclusive Savings
Balcony
$8,145
Suite
$8,977
From (Per Person)
A$8,145
Save 7,075
Per Person
View Trip
8 Day A Journey Through River Plate Elegance & Brazil’s White Shores with Explora Journeys
Cruise

8 Days (7 Nights) Buenos Aires to Rio de Janeiro
Operator: Explora Journeys
Ship: Explora I
Departure: 27 January 2028
Visits: Argentina, Uruguay, Brazil
Exclusive Savings
Suite
$6,022
From (Per Person)
A$6,022
Save 123
Per Person
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Operator: Scenic
Ships: Scenic Eclipse I
Departures: Nov 2026 to Nov 2028
Visits: Chile, Argentina
Complimentary 20min Heli Flight
Exclusive Savings
Balcony
$22,940
Suite
$32,014
From (Per Person)
A$22,940
Save 5,385
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operator: Exodus
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$9,516
Save 300
Per Person
View Trip
13 Day A Journey From Amazon Adventures To Caribbean Charms with Explora Journeys
Cruise

13 Days (12 Nights) Manaus to San Juan
Operator: Explora Journeys
Ship: Explora I
Departure: 17 February 2027
Visits: Brazil, French Guiana, Saint Vincent, Barbados +4 more, Saint Lucia, Saint Barthelemy, Saint Kitts and Nevis, Puerto Rico
Exclusive Savings
Suite
$13,544
From (Per Person)
A$13,544
Save 276
Per Person
View Trip
28 Day Ultimate Brazil, Patagonia & the Chilean Fjords with Scenic
New ReleaseCruise

28 Days (27 Nights) Rio de Janeiro to Buenos Aires
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 03 November 2027
Visits: Brazil, Uruguay, Argentina, Chile
Exclusive Savings
Balcony
$37,821
Suite
$45,185
From (Per Person)
A$37,821
Save 13,639
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Salvador to Santos
Operator: MSC Cruises
Ship: MSC Virtuosa
Departure: 30 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$960
Balcony
$1,109
Suite
$1,832
From (Per Person)
A$960
Per Person
View Trip
7 Day Galápagos Islands - Nature and Wildlife Expedition Cruise (Northern Route) with HX Expeditions
Cruise

7 Days (6 Nights) Quito to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departure: 12 December 2026
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$9,130
Suite
-
From (Per Person)
A$9,130
Save 255
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 03 November 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Balcony
$12,831
Suite
$17,138
From (Per Person)
A$12,831
Save 4,214
Per Person
View Trip
Results: 331-360 of 428

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Cape Verde Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Patagonia Cruises Peru Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wildlife Cruises

Cities

Cruises from Baltra Island Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Itajai Cruises from Lima Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Rome Cruises from Fort Lauderdale to San Juan Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Itajai to Itajai Cruises from Lima to Guayaquil Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Athens Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to Miami Cruises from New York to Fort Lauderdale Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Lisbon Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Diego to Fort Lauderdale Cruises from San Juan to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Valparaiso to Buenos Aires

Country Routes

Cruises from Peru to Argentina Cruises from French Polynesia to Australia Cruises from Australia to England Cruises from Brazil to Ecuador Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Dominican Republic to Puerto Rico Cruises from England to Holland Cruises from France to Portugal Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Iceland to France Cruises from Brazil to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Puerto Rico to Dominican Republic Cruises from Dominican Republic to USA Cruises from Spain to Turkey Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Portugal to Greece Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to Singapore Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to Turkey Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from USA to New Zealand Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Germany to USA Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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