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341 Cruises (1,815 Cruise Departures)
17 Day Mysteries of the Inca Empire with a Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Last Chance Deal
Save 197
From 9,871
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10 Day Galápagos - North, West & Central Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Jun 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,022
From 7,460
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13 Day Valparaiso to Puerto Williams with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Puerto Williams
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 07 November 2024
Countries Visited: Argentina, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,593
BALCONY
$12,276
SUITE
$19,800
From 10,593
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 December 2024
Countries Visited: Argentina, Uruguay, Brazil
Early Booking Offer
INSIDE
-
OCEANVIEW
$2,944
BALCONY
$3,260
SUITE
$4,775
From 2,944
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Jun 2025
Trip Styles: Group, Cruise, Wildlife
Countries Visited: Ecuador
Exclusive Deal
Save 1,431
From 5,211
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18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Barcelona to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 12 November 2024
Countries Visited: Spain, Morocco, Brazil
Early Booking Offer
INSIDE
$1,815
OCEANVIEW
$2,052
BALCONY
$2,646
SUITE
-
From 1,815
View Trip
34 Day Hamburg To Rio De Janeiro with Cunard
Cruise

34 Days (33 Nights) Hamburg to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 January 2025
Countries Visited: Germany, Holland, Belgium, England (+5 more), Portugal, USA, Turks and Caicos Islands, Barbados, Brazil
INSIDE
$8,216
OCEANVIEW
$9,614
BALCONY
$12,386
SUITE
$28,721
From 8,216
View Trip
16 Day Msc Grand Voyages with MSC Cruises
Cruise

16 Days (15 Nights) Sao Paulo to Vigo
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 21 April 2024
Countries Visited: Brazil, Spain, Morocco
Best Deal Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,356
SUITE
$3,950
From 2,356
View Trip
17 Day Canary Islands Crossing with Regent Seven Seas
Cruise

17 Days (16 Nights) Rio de Janeiro to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2025
Countries Visited: Brazil, Cape Verde, Spain, Portugal
Non-Use Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$10,831
SUITE
$12,316
Save 5,659
From 10,831
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16 Day Portugal, Argentina Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Lisbon to Buenos Aires
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 21 November 2025
Countries Visited: Portugal, Spain, Brazil, Uruguay (+1 more), Argentina
Exclusive Deal
INSIDE
$2,047
OCEANVIEW
$2,204
BALCONY
$2,377
SUITE
$7,934
Save 3,290
From 2,047
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17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Buenos Aires to Madeira
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 03 April 2025
Countries Visited: Argentina, Uruguay, Brazil, Spain (+1 more), Portugal
Early Booking Offer
INSIDE
-
OCEANVIEW
$2,558
BALCONY
$3,043
SUITE
-
From 2,558
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13 Day Amazon & Caribbean Adventure with Viking Cruises
Cruise
 (4)

13 Days (12 Nights) San Juan to Manaus
Cruise Line: Viking Cruises
Ship: Viking Sea
Departures: Nov 2024 to Feb 2025
Countries Visited: Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados (+2 more), French Guiana, Brazil
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$8,212
SUITE
$12,370
Save 1,089
From 8,212
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15 Day Rio De Janeiro To Cape Liberty with Celebrity Cruises
Cruise
 (2)

15 Days (14 Nights) Rio de Janeiro to New York
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 27 April 2024
Countries Visited: Brazil, Barbados, Saint Kitts and Nevis, Bermuda (+1 more), USA
Exclusive Deal
INSIDE
$4,467
OCEANVIEW
-
BALCONY
$3,738
SUITE
$8,412
Save 3,052
From 1,449
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25 Day Amazonian Mystique with Oceania Cruises
Cruise
 (1)

25 Days (24 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 November 2024
Countries Visited: USA, Antigua and Barbuda, Saint Lucia, Grenada (+7 more), Trinidad and Tobago, Brazil, Barbados, Dominica, Virgin Islands, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,720
Save 2,180
From 21,720
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28 Day Amazon Explorer with Holland America
Cruise
 (1)

28 Days (27 Nights) Miami to Miami
Cruise Line: Holland America
Ship: Zaandam
Departure: 08 February 2025
Countries Visited: USA, Sint Maarten, Saint Lucia, Trinidad and Tobago (+5 more), French Guiana, Brazil, Barbados, Dominica, Virgin Islands
Have It All Offer
INSIDE
$10,102
OCEANVIEW
-
BALCONY
$22,022
SUITE
-
From 10,102
View Trip
19 Day Brazilian Adventure with Princess
Cruise
 (3)

19 Days (18 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Princess
Ship: Majestic Princess
Departure: 03 January 2025
Countries Visited: Argentina, Brazil, Dominica, Saint Kitts and Nevis (+1 more), USA
INSIDE
$3,030
OCEANVIEW
-
BALCONY
$3,247
SUITE
$5,109
From 3,030
View Trip
19 Day Amazon Trailblazer with Oceania Cruises
Cruise
 (2)

19 Days (18 Nights) Bridgetown to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2025
Countries Visited: Barbados, Trinidad and Tobago, Brazil, French Guiana (+3 more), Grenada, Guadeloupe, Saint Lucia
Exclusive Deal
INSIDE
$9,186
OCEANVIEW
-
BALCONY
-
SUITE
$32,709
Save 2,064
From 9,186
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26 Day Amazing Amazon To Antilles with Oceania Cruises
Cruise
 (2)

26 Days (25 Nights) Bridgetown to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2025
Countries Visited: Barbados, Trinidad and Tobago, Brazil, French Guiana (+7 more), Grenada, Guadeloupe, Saint Lucia, Martinique, Saint Barthelemy, Dominica, Saint Vincent
Exclusive Deal
INSIDE
$12,106
OCEANVIEW
-
BALCONY
-
SUITE
$38,746
Save 2,084
From 12,106
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13 Day Amazon & Caribbean Adventure with Viking Cruises
Cruise
 (4)

13 Days (12 Nights) Manaus to San Juan
Cruise Line: Viking Cruises
Ship: Viking Sea
Departures: Dec 2024 to Mar 2025
Countries Visited: Brazil, French Guiana, Barbados, Saint Lucia (+2 more), Antigua and Barbuda, Puerto Rico
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$7,915
SUITE
$12,469
Save 1,090
From 7,915
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17 Day Colombia, Ecuador & Peru Voyage with Azamara Cruises
Cruise

17 Days (16 Nights) Miami to Lima
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 07 January 2025
Countries Visited: USA, Aruba, Bonaire, Curacao (+3 more), Colombia, Ecuador, Peru
INSIDE
$6,445
OCEANVIEW
$7,826
BALCONY
$9,665
SUITE
$14,263
From 6,445
View Trip
18 Day Escape & Delight In Brazil with Regent Seven Seas
Cruise

18 Days (17 Nights) Miami to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 08 January 2025
Countries Visited: USA, Dominica, Barbados, French Guiana (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,872
SUITE
$14,535
Save 10,818
From 12,872
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26 Day Emerald Reefs & Amazon Adventure with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 24 February 2025
Countries Visited: USA, Saint Barthelemy, Trinidad and Tobago, Grenada (+6 more), Brazil, Barbados, Dominica, Sint Maarten, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
$17,473
BALCONY
-
SUITE
-
Save 4,547
From 17,473
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30 Day Rio De Janeiro to Fort Lauderdale with Silversea
Cruise

30 Days (29 Nights) Rio de Janeiro to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 March 2025
Countries Visited: Brazil, French Guiana, Barbados, Saint Vincent (+5 more), Saint Lucia, Antigua and Barbuda, Virgin Islands, Puerto Rico, USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,978
From 21,978
View Trip
32 Day Mythical Secrets Of Brazil with Oceania Cruises
Cruise

32 Days (31 Nights) Buenos Aires to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil, Saint Lucia (+2 more), Saint Kitts and Nevis, USA
Exclusive Deal
INSIDE
$13,546
OCEANVIEW
$15,526
BALCONY
$17,516
SUITE
$25,436
Save 2,094
From 13,546
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22 Day Heart Of The Amazon with Oceania Cruises
Cruise

22 Days (21 Nights) Rio de Janeiro to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 17 March 2026
Countries Visited: Brazil, Saint Lucia, Saint Kitts and Nevis, USA
Exclusive Deal
INSIDE
$9,433
OCEANVIEW
$10,968
BALCONY
$12,413
SUITE
$18,106
Save 2,067
From 9,433
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18 Day San Antonio To Fort Lauderdale with Cunard
Cruise

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 February 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+3 more), Aruba, Bahamas, USA
INSIDE
$4,658
OCEANVIEW
$5,450
BALCONY
$7,232
SUITE
$16,340
From 4,658
View Trip
20 Day Amazon To Caribbean Gems with Oceania Cruises
Cruise

20 Days (19 Nights) Bridgetown to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 January 2026
Countries Visited: Barbados, Brazil, French Guiana, Trinidad and Tobago (+3 more), Grenada, Saint Vincent, Saint Lucia
Exclusive Deal
INSIDE
$8,405
OCEANVIEW
$9,246
BALCONY
$13,296
SUITE
$19,275
Save 2,055
From 8,405
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26 Day Call Of The Amazon with Oceania Cruises
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 12 November 2025
Countries Visited: USA, Antigua and Barbuda, Saint Lucia, Grenada (+6 more), Trinidad and Tobago, Brazil, Barbados, Dominica, Sint Maarten, Puerto Rico
Exclusive Deal
INSIDE
$10,748
OCEANVIEW
$11,511
BALCONY
$16,094
SUITE
$22,589
Save 2,072
From 10,748
View Trip
25 Day Radiant Amazon with Regent Seven Seas
Cruise

25 Days (24 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 17 November 2024
Countries Visited: USA, Saint Barthelemy, Trinidad and Tobago, Grenada (+6 more), Brazil, Barbados, Dominica, Sint Maarten, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$19,313
SUITE
$21,016
Save 5,767
From 19,313
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42 Day Caribbean & Amazon Icons with Oceania Cruises
Cruise

42 Days (41 Nights) Boston to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 October 2025
Countries Visited: USA, Bermuda, Saint Barthelemy, Antigua and Barbuda (+10 more), Saint Lucia, Barbados, Grenada, Bonaire, Aruba, Trinidad and Tobago, Brazil, Dominica, Sint Maarten, Puerto Rico
Exclusive Deal
INSIDE
$15,016
OCEANVIEW
$15,778
BALCONY
$22,342
SUITE
$31,272
Save 2,094
From 15,016
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Results: 181-210 of 341

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South & Central America Cruises

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Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

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Routes

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Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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