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All South America Cruises

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428 Cruises (2,126 Departures)
428 Cruises (2,126 Departures)
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Duration
2 Days
141 Days
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Price
$200pp
$133,895pp
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4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$874
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Barcelona to Santos
Operator: MSC Cruises
Ship: MSC Divina
Departure: 01 November 2027
Visits: Spain, Brazil
Exclusive Savings
Inside
$2,235
Oceanview
$2,541
Balcony
$2,888
Suite
-
From (Per Person)
A$2,235
Per Person
View Trip
31 Day World Cruise: South America To French Polynesia with Seabourn
Cruise
 (1)

31 Days (30 Nights) Miami to Tahiti
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2029
Visits: USA, Colombia, Panama, Ecuador, Peru, Chile, French Polynesia
Exclusive Savings
Oceanview
$23,678
Balcony
$28,578
Suite
$49,550
From (Per Person)
A$23,678
Save 421
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
$2,164
From (Per Person)
A$1,280
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,716
Suite
$2,362
From (Per Person)
A$1,280
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Operator: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Mar 2027 to Mar 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,792
Oceanview
$4,188
Balcony
$5,920
Suite
$7,900
From (Per Person)
A$3,792
Per Person
View Trip
11 Day Brazil Intensive Cruise: Rio De Janeiro, Paraty & Sao Paolo with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Operator: Azamara
Ship: Azamara Journey
Departure: 07 February 2027
Visits: Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$4,565
Oceanview
$5,104
Balcony
$6,799
Suite
-
From (Per Person)
A$4,565
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Divina
Departure: 05 February 2027
Visits: Brazil
Exclusive Savings
Inside
$1,248
Oceanview
$1,416
Balcony
$1,545
Suite
$1,851
From (Per Person)
A$1,248
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 02 December 2026
Visits: Brazil
Exclusive Savings
Inside
$834
Oceanview
$943
Balcony
$1,092
Suite
$1,419
From (Per Person)
A$834
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Dec 2027
Visits: Brazil
Exclusive Savings
Inside
$2,538
Oceanview
$2,755
Balcony
$3,013
Suite
$5,441
From (Per Person)
A$2,538
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Barcelona
Operator: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil, Spain, Morocco
Exclusive Savings
Inside
$2,328
Oceanview
$2,695
Balcony
$3,358
Suite
-
From (Per Person)
A$2,328
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Operator: Oceania
Ship: Oceania Insignia
Departure: 03 January 2027
Visits: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$10,897
Oceanview
$11,460
Balcony
$18,366
From (Per Person)
A$10,897
Save 2,253
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

19 Days (18 Nights) Rio de Janeiro to Rome
Operator: MSC Cruises
Ship: MSC Divina
Departure: 20 March 2028
Visits: Brazil, Spain, Morocco, Italy
Exclusive Savings
Inside
$2,100
Oceanview
$2,694
Balcony
$3,436
Suite
$5,020
From (Per Person)
A$2,100
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Genoa to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2027
Visits: Italy, France, Spain, Brazil
Exclusive Savings
Inside
$2,433
Oceanview
$2,819
Balcony
$3,185
Suite
-
From (Per Person)
A$2,433
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Rio de Janeiro to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$693
Balcony
$921
Suite
$2,222
From (Per Person)
A$693
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Operator: Oceania
Ship: Oceania Sirena
Departure: 05 January 2028
Visits: USA, Cayman Islands, Jamaica, Colombia +12 more, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Exclusive Savings
Inside
$34,659
Oceanview
$35,706
Balcony
-
Suite
-
From (Per Person)
A$34,659
Save 2,771
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

19 Days (18 Nights) Genoa to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 06 November 2027
Visits: Italy, France, Spain, Portugal, Brazil
Exclusive Savings
Inside
$2,325
Oceanview
$2,810
Balcony
$3,731
Suite
$10,866
From (Per Person)
A$2,325
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (6)

20 Days (19 Nights) Miami to Valparaiso
Operator: Azamara
Ship: Azamara Quest
Departure: 05 January 2028
Visits: USA, Mexico, Belize, Honduras +5 more, Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$10,451
Oceanview
$11,804
Balcony
$14,283
Suite
$18,821
From (Per Person)
A$10,451
Save 158
Per Person
View Trip
57 Day Miami To Sydney Grand Voyage with Azamara Cruises
Cruise
 (8)

57 Days (56 Nights) Miami to Sydney
Operator: Azamara
Ship: Azamara Onward
Departure: 05 January 2028
Visits: USA, Aruba, Curacao, Colombia +8 more, Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand, Australia
Azamara Always Included
Exclusive Savings
Inside
$28,636
Oceanview
$29,331
Balcony
$36,672
Suite
-
From (Per Person)
A$28,636
Save 453
Per Person
View Trip
41 Day Amazon & Tropical Isles with Oceania Cruises
Cruise
 (1)

41 Days (40 Nights) Lisbon to Miami
Operator: Oceania
Ship: Oceania Insignia
Departure: 09 November 2026
Visits: Portugal, Spain, Puerto Rico, Dominican Republic +10 more, USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin, Bahamas
Your World Inclusions
Exclusive Savings
Oceanview
$32,911
From (Per Person)
A$32,911
Save 2,859
Per Person
View Trip
18 Day Antarctica & Patagonia Expedition with HX Expeditions
Cruise
 (1)

18 Days (17 Nights) Valparaiso to Buenos Aires
Operator: HX Expeditions
Ship: MS Fridtjof Nansen
Departure: 26 October 2027
Visits: Chile, Antarctica, Argentina
Exclusive Savings
Oceanview
$18,401
Balcony
$22,445
Suite
$25,418
From (Per Person)
A$18,401
Save 349
Per Person
View Trip
13 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Valparaiso
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 12 March 2028
Visits: Argentina, Uruguay, Chile
Exclusive Savings
Inside
$2,793
Oceanview
$3,095
Balcony
$3,232
Suite
$9,565
From (Per Person)
A$2,793
Save 1,675
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 07 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,001
Suite
$3,959
From (Per Person)
A$2,001
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Salvador to Salvador
Operator: MSC Cruises
Ship: MSC Virtuosa
Departure: 05 January 2028
Visits: Brazil
Exclusive Savings
Inside
$1,510
Oceanview
$1,768
Balcony
$2,154
Suite
$3,734
From (Per Person)
A$1,510
Per Person
View Trip
26 Day South American Discovery with Santiago Stopover & Galápagos Cruise with Globus
Tour + Cruise

26 Days Santiago to Guayaquil
Operator: Globus
Departures: Apr 2027 to Nov 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Chile, Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$22,327
Save 616
Per Person
View Trip
8 Day A Journey Through Golden Shores, Rainforests & Tango with Explora Journeys
Cruise

8 Days (7 Nights) Rio de Janeiro to Buenos Aires
Operator: Explora Journeys
Ship: Explora I
Departures: Dec 2027 to Feb 2028
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Suite
$6,022
From (Per Person)
A$6,022
Save 123
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,503
Save 1,516
Per Person
View Trip
15 Day Empires Of The Sun with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Lima
Operator: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 13 January 2028
Visits: USA, Cayman Islands, Jamaica, Colombia +4 more, Costa Rica, Panama, Ecuador, Peru
Exclusive Savings
Balcony
$24,341
Suite
$25,681
From (Per Person)
A$24,341
Save 9,059
Per Person
View Trip
131 Day Grand World Voyage with Holland America
Cruise

131 Days (130 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Volendam
Departure: 04 January 2028
Visits: USA, Barbados, French Guiana, Brazil +22 more, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Pitcairn Islands, French Polynesia, New Zealand, Australia, Indonesia, Singapore, Thailand, Sri Lanka, Maldives, Mauritius, Reunion, South Africa, Namibia, Ghana, Cote d'Ivoire, Cape Verde, Puerto Rico
Advantage Fare
Exclusive Savings
Inside
$44,740
Oceanview
$49,195
Balcony
$85,726
Suite
$151,660
From (Per Person)
A$44,740
Per Person
View Trip
141 Day 2029 World Cruise: Melbourne to Portsmouth with Crystal Cruises
New ReleaseCruise

141 Days (140 Nights) Melbourne to London
Operator: Crystal
Ship: Crystal Symphony
Departure: 07 January 2029
Visits: Australia, Indonesia, New Zealand, Fiji +21 more, Samoa, American Samoa, French Polynesia, Pitcairn Islands, Chile, Argentina, Falkland Islands, Uruguay, Brazil, French Guiana, Barbados, Dominica, Saint Kitts and Nevis, Puerto Rico, Dominican Republic, Turks and Caicos Islands, USA, Bermuda, Canada, Ireland, England
Exclusive Savings
Oceanview
$103,777
Balcony
$130,102
Suite
$134,977
From (Per Person)
A$103,777
Save 2,223
Per Person
View Trip
Results: 151-180 of 428

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Cape Verde Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Patagonia Cruises Peru Cruises South America Cruises Spain Cruises Uruguay Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wildlife Cruises

Cities

Cruises from Baltra Island Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Itajai Cruises from Lima Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Rome Cruises from Fort Lauderdale to San Juan Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Itajai to Itajai Cruises from Lima to Guayaquil Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Athens Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to Miami Cruises from New York to Fort Lauderdale Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Lisbon Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Diego to Fort Lauderdale Cruises from San Juan to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Valparaiso to Buenos Aires

Country Routes

Cruises from Peru to Argentina Cruises from French Polynesia to Australia Cruises from Australia to England Cruises from Brazil to Ecuador Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Dominican Republic to Puerto Rico Cruises from England to Holland Cruises from France to Portugal Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Iceland to France Cruises from Brazil to USA Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Puerto Rico to Dominican Republic Cruises from Dominican Republic to USA Cruises from Spain to Turkey Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Portugal to Greece Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to Singapore Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to Turkey Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from USA to New Zealand Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Germany to USA Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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