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South America Cruises Starting In January 2027, 2028 and 2029

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145 Cruises (1,482 Departures)
145 Cruises (1,482 Departures)
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140 Days
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$200pp
$133,895pp
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22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Operator: Oceania
Ship: Oceania Insignia
Departure: 03 January 2027
Visits: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$10,897
Oceanview
$11,460
Balcony
$18,366
From (Per Person)
A$10,897
Save 2,253
Per Person
View Trip
11 Day Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao) with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Panama City to Valparaiso
Operator: Azamara
Ship: Azamara Quest
Departure: 14 January 2028
Visits: Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$5,175
Oceanview
$6,057
Balcony
$7,420
Suite
$10,967
From (Per Person)
A$5,175
Save 84
Per Person
View Trip
31 Day World Cruise: South America To French Polynesia with Seabourn
Cruise
 (1)

31 Days (30 Nights) Miami to Tahiti
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2029
Visits: USA, Colombia, Panama, Ecuador, Peru, Chile, French Polynesia
Exclusive Savings
Oceanview
$23,678
Balcony
$28,578
Suite
$49,550
From (Per Person)
A$23,678
Save 421
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) Santiago to Buenos Aires
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 08 January 2028
Visits: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$7,571
Oceanview
$8,017
Balcony
$11,680
Suite
$14,947
From (Per Person)
A$7,571
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Feb 2027 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$802
Oceanview
$951
Balcony
$1,149
Suite
$1,455
From (Per Person)
A$802
Per Person
View Trip
84 Day Miami To Hong Kong Grand Voyage with Azamara Cruises
Cruise
 (8)

84 Days (83 Nights) Miami to Hong Kong
Operator: Azamara
Ship: Azamara Onward
Departure: 05 January 2028
Visits: USA, Aruba, Curacao, Colombia +12 more, Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand, Australia, Indonesia, Malaysia, Philippines, China
Azamara Always Included
Exclusive Savings
Inside
$35,002
Oceanview
$35,511
Balcony
$43,694
Suite
-
From (Per Person)
A$35,002
Save 527
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 24 January 2027
Visits: Brazil
Exclusive Savings
Inside
$1,468
Oceanview
$1,627
Balcony
$1,904
Suite
$2,995
From (Per Person)
A$1,468
Per Person
View Trip
36 Day World Cruise: Panama Canal Crossing & Polynesia with Seabourn
Cruise
 (1)

36 Days (35 Nights) Miami to Tahiti
Operator: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visits: USA, Panama, Ecuador, Peru, Chile, French Polynesia
Exclusive Savings
Oceanview
$23,762
Balcony
-
Suite
-
From (Per Person)
A$23,762
Save 436
Per Person
View Trip
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visits: USA, Panama, Ecuador, Peru +5 more, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Savings
Oceanview
$51,368
Balcony
$66,495
Suite
-
From (Per Person)
A$51,368
Save 930
Per Person
View Trip
84 Day World Cruise: South Pacific, New Zealand & Australia with Seabourn
Cruise
 (1)

84 Days (83 Nights) Miami to Singapore
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2029
Visits: USA, Colombia, Panama, Ecuador +11 more, Peru, Chile, French Polynesia, Tonga, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Indonesia, Singapore
Exclusive Savings
Oceanview
$64,356
Balcony
$77,978
Suite
$135,896
From (Per Person)
A$64,356
Save 1,143
Per Person
View Trip
71 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (5)

71 Days (70 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visits: USA, Cayman Islands, Panama, Ecuador +12 more, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Barbados, Saint Lucia, Saint Kitts and Nevis, Puerto Rico
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$21,406
Oceanview
$24,376
Balcony
$44,176
Suite
$87,043
From (Per Person)
A$21,406
Per Person
View Trip
15 Day South America & Antarctica with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ships: Celebrity Equinox
Departures: Jan 2027 to Feb 2029
Visits: Argentina, Chile, Antarctica, Falkland Islands, Uruguay
Exclusive Savings
Inside
$4,103
Oceanview
$4,709
Balcony
$5,545
Suite
$12,730
From (Per Person)
A$4,103
Save 5,718
Per Person
View Trip
140 Day World Cruise: Iconic Islands & Remote Horizons with Seabourn
Cruise
 (1)

140 Days (139 Nights) Miami to Lisbon
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2029
Visits: USA, Colombia, Panama, Ecuador +26 more, Peru, Chile, French Polynesia, Tonga, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Tanzania, Madagascar, Mauritius, Reunion, South Africa, Namibia, Senegal, Cape Verde, Spain, Portugal
Exclusive Savings
Oceanview
$119,449
Balcony
$144,635
Suite
$252,533
From (Per Person)
A$119,449
Save 2,150
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Valparaiso
Operator: Oceania
Ship: Oceania Insignia
Departure: 24 January 2027
Visits: Argentina, Falkland Islands, Antarctica, Chile
Your World Inclusions
Exclusive Savings
Balcony
$14,842
Suite
$19,993
From (Per Person)
A$14,842
Save 2,378
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) Buenos Aires to Santiago
Operator: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Feb 2027 to Jan 2028
Visits: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Have It All Fare Option
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$6,977
Oceanview
$7,274
Balcony
$9,601
Suite
$12,719
From (Per Person)
A$6,977
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departure: 26 January 2027
Visits: Brazil
Exclusive Savings
Inside
$884
Oceanview
$1,013
Balcony
$1,122
Suite
$1,419
From (Per Person)
A$884
Per Person
View Trip
18 Day Antarctica & Patagonia with Princess
Cruise
 (8)

18 Days (17 Nights) Buenos Aires to Buenos Aires
Operator: Princess
Ship: Majestic Princess
Departures: Jan 2027 to Jan 2028
Visits: Argentina, Chile, Antarctica, Falkland Islands, Uruguay
Exclusive Savings
Inside
$4,971
Oceanview
-
Balcony
$6,124
Suite
$7,461
From (Per Person)
A$4,971
Save 86
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) Valparaiso to Buenos Aires
Operator: Holland America
Ship: Oosterdam
Departure: 10 January 2027
Visits: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Have It All Fare Option
Exclusive Savings
Inside
$8,036
Oceanview
$8,175
Balcony
$11,293
Suite
$14,135
From (Per Person)
A$8,036
Per Person
View Trip
121 Day Cape To Cape World Cruise: Miami To Southampton with Seabourn
Cruise
 (1)

121 Days (120 Nights) Miami to London
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visits: USA, Panama, Ecuador, Peru +20 more, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Exclusive Savings
Oceanview
$108,240
Balcony
-
Suite
$275,722
From (Per Person)
A$108,240
Save 1,959
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia +3 more, MSC Musica, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$854
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
60 Day World Cruise: South America & South Pacific Discovery with Seabourn
Cruise
 (1)

60 Days (59 Nights) Miami to Sydney
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2029
Visits: USA, Colombia, Panama, Ecuador +9 more, Peru, Chile, French Polynesia, Tonga, Fiji, Vanuatu, New Caledonia, New Zealand, Australia
Exclusive Savings
Oceanview
$45,589
Balcony
$55,095
Suite
$104,482
From (Per Person)
A$45,589
Save 810
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Operator: Oceania
Ship: Oceania Sirena
Departure: 05 January 2028
Visits: USA, Cayman Islands, Jamaica, Colombia +12 more, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Exclusive Savings
Inside
$34,659
Oceanview
$35,706
Balcony
-
Suite
-
From (Per Person)
A$34,659
Save 2,771
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 23 January 2027
Visits: Brazil
Exclusive Savings
Inside
$1,468
Oceanview
$1,627
Balcony
$2,013
Suite
$2,995
From (Per Person)
A$1,468
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
$2,164
From (Per Person)
A$1,280
Per Person
View Trip
13 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 02 January 2029
Visits: Argentina, Uruguay, Chile
Exclusive Savings
Inside
$2,594
Oceanview
$2,897
Balcony
$3,034
Suite
$10,048
From (Per Person)
A$2,594
Save 1,516
Per Person
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operator: Cosmos
Departures: Jun 2027 to Nov 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,900
Save 363
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ships: MSC Meraviglia, MSC Seaview
Departures: Dec 2026 to Mar 2028
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,458
Oceanview
$1,656
Balcony
$2,112
Suite
$3,441
From (Per Person)
A$1,458
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galápagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operator: Globus
Departures: Mar 2027 to Nov 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,774
Save 466
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Visits: Ecuador
Exclusive Savings
From (Per Person)
A$6,280
Save 1,259
Per Person
View Trip
116 Day MSC World Cruise with MSC Cruises
Cruise

116 Days (115 Nights) Barcelona to Barcelona
Operator: MSC Cruises
Ship: MSC Magnifica
Departure: 07 January 2028
Visits: Spain, Turks and Caicos Islands, Bahamas, Panama +22 more, Ecuador, Peru, Chile, French Polynesia, Tonga, New Caledonia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Cambodia, Singapore, Malaysia, Sri Lanka, India, United Arab Emirates, Oman, Jordan, Egypt, Italy, France
Exclusive Savings
Inside
-
Oceanview
$37,477
Balcony
$49,703
Suite
-
From (Per Person)
A$37,477
Per Person
View Trip
Results: 31-60 of 145

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South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

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Countries

Antarctica Argentina Barbados Brazil Cape Verde Chile Ecuador Falkland Islands France Galapagos Morocco Panama Peru South Georgia Island Spain Uruguay

Cities

Cruises from Baltra Island Cruises from Barcelona Cruises from Bridgetown Cruises from Buenos Aires Cruises from Colon Cruises from Itajai Cruises from Lima Cruises from Maceio Cruises from Manaus Cruises from Marseille Cruises from Panama City Cruises from Puerto Williams Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Fort Lauderdale to Rome Cruises from Fort Lauderdale to San Juan Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Itajai to Itajai Cruises from Lima to Guayaquil Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Athens Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to Miami Cruises from New York to Fort Lauderdale Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Reykjavik to London Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Lisbon Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Diego to Fort Lauderdale Cruises from San Juan to Fort Lauderdale Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Valparaiso to Buenos Aires

Country Routes

Cruises from Peru to Argentina Cruises from Brazil to Ecuador Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Dominican Republic to Puerto Rico Cruises from England to Holland Cruises from France to Portugal Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Iceland to France Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Puerto Rico to Dominican Republic Cruises from Dominican Republic to USA Cruises from Spain to Turkey Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Portugal to Greece Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to Singapore Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to Turkey Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from USA to New Zealand Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Germany to USA Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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