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South America Cruises Starting In January 2027, 2028 and 2029

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128 Cruises (1,238 Cruise Departures)
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 January 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,607
Oceanview
$1,854
Balcony
$2,191
Suite
$2,382
From
A$1,607
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 24 January 2027
Visit: Brazil
Exclusive Savings
Inside
$1,488
Oceanview
$1,676
Balcony
$2,023
Suite
-
From
A$1,488
Per Person
View Trip
16 Day South America & Antarctica with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departures: Jan 2028 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Just Cruise Fare
Exclusive Savings
Inside
$5,141
Oceanview
$5,588
Balcony
$8,193
Suite
$8,640
From
A$5,141
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2027
Visit: Brazil
Exclusive Savings
Inside
$1,488
Oceanview
$1,587
Balcony
$1,736
Suite
-
From
A$1,488
Per Person
View Trip
35 Day South America Cruise: Miami, Rio De Janeiro & Buenos Aires with Azamara Cruises
Cruise
 (4)

35 Days (34 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+10 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$16,910
Oceanview
$17,057
Balcony
-
Suite
$32,669
From
A$16,910
Save 259
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 23 January 2027
Visit: Brazil
Exclusive Savings
Inside
$1,488
Oceanview
$1,647
Balcony
$2,023
Suite
-
From
A$1,488
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Exclusive Savings
Inside
$30,226
Oceanview
$31,332
Balcony
$41,585
Suite
-
From
A$30,226
Save 2,634
Per Person
View Trip
50 Day Valparaiso To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (5)

50 Days (49 Nights) Valparaiso to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+5 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$24,424
Oceanview
$26,198
Balcony
$31,656
Suite
$54,118
From
A$24,424
Save 385
Per Person
View Trip
146 Day World Cruise: Australia & South Pacific Panorama with Seabourn
Cruise
 (1)

146 Days (145 Nights) Miami to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru (+15 more), Chile, French Polynesia, Cook Islands, Tonga, New Zealand, Australia, Papua New Guinea, New Caledonia, Vanuatu, Fiji, Samoa, Mexico, Guatemala, Costa Rica, Colombia
Exclusive Savings
Inside
-
Oceanview
$118,698
Balcony
$143,551
Suite
$368,451
From
A$118,698
Save 2,221
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Feb 2027 to Jan 2028
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Fare Saver
Exclusive Savings
Inside
$6,977
Oceanview
$7,274
Balcony
$9,601
Suite
$12,719
From
A$6,977
Save 108
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (5)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Exclusive Savings
Inside
$38,419
Oceanview
$41,555
Balcony
$50,286
Suite
$72,797
From
A$38,419
Save 600
Per Person
View Trip
30 Day Panama Canal & Easter Island Explorer with Seabourn
Cruise
 (1)

30 Days (29 Nights) Miami to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru, Chile
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
$26,125
Balcony
$31,123
Suite
$54,937
From
A$26,125
Save 473
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,458
Oceanview
$1,706
Balcony
$1,963
Suite
$2,085
From
A$1,458
Per Person
View Trip
127 Day World Cruise: Australia & South Pacific Panorama with Seabourn
Cruise
 (1)

127 Days (126 Nights) Miami to Los Angeles
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru (+11 more), Chile, French Polynesia, Cook Islands, Tonga, New Zealand, Australia, Papua New Guinea, New Caledonia, Vanuatu, Fiji, Samoa
Exclusive Savings
Inside
-
Oceanview
$106,040
Balcony
$126,679
Suite
-
From
A$106,040
Save 1,989
Per Person
View Trip
21 Day Bridgetown to Rio De Janeiro with Silversea
Cruise
 (1)

21 Days (20 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Nova
Departure: 18 January 2027
Visit: Barbados, Brazil
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$24,069
Suite
$39,788
From
A$24,069
Save 6,631
Per Person
View Trip
43 Day Miami To Buenos Aires Grand Voyage with Azamara Cruises
Cruise
 (5)

43 Days (42 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+9 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Exclusive Savings
Inside
$20,569
Oceanview
$22,755
Balcony
$27,527
Suite
$41,110
From
A$20,569
Save 320
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$9,316
Oceanview
$9,801
Balcony
$15,388
Suite
-
From
A$9,316
Save 2,204
Per Person
View Trip
15 Day Panama Canal To Machu Picchu with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia, Panama, Ecuador, Peru
Your World Inclusions
Exclusive Savings
Inside
$6,214
Oceanview
$6,825
Balcony
$8,804
Suite
$12,082
From
A$6,214
Save 2,116
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
$4,469
Oceanview
$5,234
Balcony
$6,419
Suite
$9,820
From
A$4,469
Save 70
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2027
Visit: Brazil
Exclusive Savings
Inside
$1,389
Oceanview
$1,548
Balcony
$1,924
Suite
-
From
A$1,389
Per Person
View Trip
59 Day Valparaiso To Miami Grand Voyage with Azamara Cruises
Cruise
 (5)

59 Days (58 Nights) Valparaiso to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+12 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands, USA
Azamara Always Included
Exclusive Savings
Inside
$28,370
Oceanview
$30,682
Balcony
$37,101
Suite
$63,797
From
A$28,370
Save 449
Per Person
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (4)

24 Days (23 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 January 2027
Visit: Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Exclusive Savings
Inside
$9,397
Oceanview
$10,475
Balcony
$13,052
Suite
$18,540
From
A$9,397
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,409
Oceanview
$1,656
Balcony
$1,993
Suite
$2,085
From
A$1,409
Per Person
View Trip
24 Day Chile, Antarctica & Falkland Islands Cruise: Chilean Fjords, Ushuaia & Montevideo with Azamara Cruises
Cruise
 (5)

24 Days (23 Nights) Valparaiso to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Exclusive Savings
Inside
$10,422
Oceanview
$12,235
Balcony
$14,911
Suite
$25,289
From
A$10,422
Save 167
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 January 2027
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,607
Oceanview
$1,854
Balcony
$2,211
Suite
$2,914
From
A$1,607
Per Person
View Trip
42 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (4)

42 Days (41 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Advantage Fare
Exclusive Savings
Inside
$15,360
Oceanview
$17,092
Balcony
$30,061
Suite
$59,712
From
A$15,360
Per Person
View Trip
71 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (4)

71 Days (70 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+12 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Barbados, Saint Lucia, Saint Kitts and Nevis, Puerto Rico
Advantage Fare
Exclusive Savings
Inside
$23,337
Oceanview
$26,010
Balcony
$46,206
Suite
$92,241
From
A$23,337
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 10 January 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,686
Oceanview
$1,934
Balcony
$2,191
Suite
$2,382
From
A$1,686
Per Person
View Trip
37 Day Antarctic Voyage with South America and Galápagos Islands with APT
New ReleaseTour + Cruise

37 Days Guayaquil to Rio de Janeiro or Quito to Rio de Janeiro
Operated By: APT
Ships: Seabourn Venture
Departures: Jan 2027 to Jan 2028
Visit: Ecuador, Galapagos, Peru, Argentina, Antarctica, Brazil
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$55,029
Suite
$57,969
From
A$55,029
Save 6,055
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2026 to Mar 2028
Visit: Ecuador, Galapagos
Last Minute Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,357
Suite
$28,420
From
A$14,357
Save 5,486
Per Person
View Trip
Results: 31-60 of 128

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Travel Styles

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Countries

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Cities

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Routes

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Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from England to Holland Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Iceland to USA Cruises from Puerto Rico to USA Cruises from Iceland to Holland Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from Iceland to Canada Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Portugal Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from Iceland to England Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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