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203 Cruises (490 Cruise Departures)
18 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

18 Days (17 Nights) Lima to San Diego
Ship: Norwegian Jade
Departure: 11 March 2026
Countries Visited: Peru, Ecuador, Panama, Costa Rica (+5 more), Nicaragua, El Salvador, Guatemala, Mexico, USA
Free At Sea Offer
INSIDE
$4,812
OCEANVIEW
$5,466
BALCONY
$7,849
SUITE
$8,684
From 4,812
View Trip
13 Day Fort Lauderdale to Lima with Silversea
Cruise

13 Days (12 Nights) Fort Lauderdale to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 20 January 2025
Countries Visited: Ecuador, Mexico, Panama, Peru (+1 more), USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,791
From 10,791
View Trip
27 Day Southampton To San Francisco with Cunard
Cruise

27 Days (26 Nights) London to San Francisco
Cruise Line: Cunard
Ship: Queen Anne
Departure: 09 January 2025
Countries Visited: England, USA, Aruba, Panama (+2 more), Guatemala, Mexico
INSIDE
$6,730
OCEANVIEW
$9,364
BALCONY
$10,354
SUITE
$19,808
From 6,730
View Trip
16 Day Caribbean & Panama Canal with Viking Cruises
Cruise
 (4)

16 Days (15 Nights) San Juan to Los Angeles
Cruise Line: Viking Cruises
Ship: Viking Sea
Departure: 29 March 2026
Countries Visited: Puerto Rico, Curacao, Colombia, Panama (+3 more), Costa Rica, Mexico, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$8,410
SUITE
$16,825
Save 1,085
From 8,410
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Harmony of the Seas (+2 more), Harmony of the Seas, Harmony of the Seas
Departures: Apr 2024 to Apr 2026
Countries Visited: USA, Honduras, Mexico
Exclusive Deal
INSIDE
$1,177
OCEANVIEW
$1,622
BALCONY
$1,597
SUITE
$3,001
Save 1,620
From 1,051
View Trip
21 Day Panoramic Panama Canal with Oceania Cruises
Cruise

21 Days (20 Nights) San Diego to New York
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 July 2025
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+3 more), Costa Rica, Colombia, Cayman Islands
Exclusive Deal
INSIDE
$9,135
OCEANVIEW
$9,590
BALCONY
$13,095
SUITE
$19,698
Save 2,065
From 9,135
View Trip
35 Day Caribbean Gems & Panama Canal with Seabourn
Cruise

35 Days (34 Nights) Miami to Los Angeles
Cruise Line: Seabourn
Ship: Sojourn
Departure: 13 November 2025
Countries Visited: USA, Puerto Rico, Saint Barthelemy, Guadeloupe (+9 more), Dominica, Saint Kitts and Nevis, Virgin Islands, Dominican Republic, Curacao, Colombia, Costa Rica, Guatemala, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
$17,866
BALCONY
$22,816
SUITE
$38,854
From 17,866
View Trip
18 Day Pacific & Island Holiday with Oceania Cruises
Cruise

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 20 December 2025
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+3 more), Costa Rica, Colombia, Cayman Islands
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,041
SUITE
$16,545
Save 2,089
From 11,041
View Trip
32 Day Western Caribbean Explorer & Panama Canal with Holland America
Cruise

32 Days (31 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 02 April 2025
Countries Visited: USA, Bahamas, Jamaica, Honduras (+6 more), Belize, Mexico, Colombia, Costa Rica, Guatemala, Canada
Have It All Offer
INSIDE
$8,713
OCEANVIEW
$9,525
BALCONY
$11,109
SUITE
$17,069
From 8,713
View Trip
23 Day Panama Canal Passage with Seabourn
Cruise

23 Days (22 Nights) Miami to Los Angeles
Cruise Line: Seabourn
Ship: Sojourn
Departure: 25 November 2025
Countries Visited: USA, Dominican Republic, Curacao, Colombia (+3 more), Costa Rica, Guatemala, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,913
BALCONY
$14,883
SUITE
$25,179
From 11,913
View Trip
17 Day Panama Canal Adventure with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 08 January 2025
Countries Visited: USA, Cayman Islands, Colombia, Costa Rica (+3 more), Nicaragua, Guatemala, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,783
SUITE
$16,644
Save 2,077
From 9,783
View Trip
30 Day Bridgetown to Los Angeles with Silversea
Cruise

30 Days (29 Nights) Bridgetown to Los Angeles
Cruise Line: Silversea
Ship: Silver Moon
Departure: 21 March 2025
Countries Visited: Barbados, Saint Vincent, Saint Lucia, Martinique (+12 more), Antigua and Barbuda, Virgin Islands, Saint Barthelemy, Saint Martin, Puerto Rico, Turks and Caicos Islands, USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$15,246
BALCONY
$19,206
SUITE
$33,066
From 15,246
View Trip
16 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 19 September 2024
Countries Visited: USA, Mexico, Costa Rica, Colombia (+1 more), Cayman Islands
Exclusive Offer
INSIDE
$2,576
OCEANVIEW
$3,108
BALCONY
$6,749
SUITE
$13,217
Save 3,840
From 2,576
View Trip
26 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

26 Days (25 Nights) Tampa to Whittier
Ship: Norwegian Jade
Departure: 03 April 2025
Countries Visited: USA, Colombia, Panama, Costa Rica (+3 more), Nicaragua, Guatemala, Mexico
Free At Sea Offer
INSIDE
$6,322
OCEANVIEW
$7,006
BALCONY
$9,739
SUITE
$11,484
From 6,322
View Trip
31 Day Western Caribbean Explorer & Panama Canal with Holland America
Cruise

31 Days (30 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 02 April 2025
Countries Visited: USA, Bahamas, Jamaica, Honduras (+6 more), Belize, Mexico, Colombia, Costa Rica, Guatemala, Canada
Have It All Offer
INSIDE
$8,410
OCEANVIEW
$9,212
BALCONY
$10,796
SUITE
$16,756
From 8,410
View Trip
25 Day Western Caribbean Explorer & Panama Canal with Holland America
Cruise

25 Days (24 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 02 April 2025
Countries Visited: USA, Bahamas, Jamaica, Honduras (+5 more), Belize, Mexico, Colombia, Costa Rica, Guatemala
Have It All Offer
INSIDE
$7,385
OCEANVIEW
$8,187
BALCONY
$9,771
SUITE
$15,731
From 7,385
View Trip
17 Day Panama Canal Adventure with Oceania Cruises
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2025
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+3 more), Costa Rica, Colombia, Cayman Islands
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,181
SUITE
$16,665
Save 2,089
From 11,181
View Trip
34 Day Los Angeles to New York with Silversea
Cruise

34 Days (33 Nights) Los Angeles to New York
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 09 May 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+5 more), Colombia, Aruba, Jamaica, Virgin Islands, Bermuda
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$13,959
BALCONY
$17,622
SUITE
$40,194
From 13,959
View Trip
18 Day New York To San Francisco with Cunard
Cruise

18 Days (17 Nights) New York to San Francisco
Cruise Line: Cunard
Ship: Queen Anne
Departure: 18 January 2025
Countries Visited: USA, Aruba, Panama, Guatemala (+1 more), Mexico
INSIDE
$4,945
OCEANVIEW
$7,242
BALCONY
$7,846
SUITE
$16,231
From 4,945
View Trip
24 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

24 Days (23 Nights) Orlando to Seattle
Ship: Norwegian Joy
Departure: 11 April 2026
Countries Visited: USA, Bahamas, Colombia, Panama (+4 more), Costa Rica, Guatemala, Mexico, Canada
Free At Sea Offer
INSIDE
$6,210
OCEANVIEW
$7,774
BALCONY
$9,475
SUITE
$10,538
From 6,210
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 23 September 2025
Countries Visited: Canada, USA, Mexico, Nicaragua (+3 more), Costa Rica, Panama, Aruba
INSIDE
$3,995
OCEANVIEW
$4,399
BALCONY
$5,975
SUITE
$8,133
From 3,995
View Trip
15 Day Inca & Aztec Kingdoms with Oceania Cruises
Cruise

15 Days (14 Nights) Lima to San Diego
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 21 February 2026
Countries Visited: Peru, Ecuador, Costa Rica, Nicaragua (+3 more), El Salvador, Mexico, USA
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,906
SUITE
$12,005
Save 2,064
From 7,906
View Trip
36 Day Tropical Escapades, East To West with Regent Seven Seas
Cruise

36 Days (35 Nights) Miami to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 11 January 2026
Countries Visited: USA, Colombia, Costa Rica, Nicaragua (+4 more), Guatemala, Mexico, Kiribati, French Polynesia
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$37,512
SUITE
$40,314
Save 13,378
From 37,512
View Trip
52 Day Panama Canal, Hawaii & South Pacific Discovery with Seabourn
Cruise

52 Days (51 Nights) Miami to Auckland
Cruise Line: Seabourn
Ship: Quest
Departure: 09 November 2024
Countries Visited: USA, Colombia, Costa Rica, Guatemala (+6 more), Mexico, French Polynesia, Cook Islands, Niue, Tonga, New Zealand
Exclusive Deal
INSIDE
-
OCEANVIEW
$36,097
BALCONY
$43,225
SUITE
-
From 36,097
View Trip
41 Day Seattle To Miami with Cunard
Cruise
 (8)

41 Days (40 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 September 2025
Countries Visited: USA, Canada, Mexico, Costa Rica (+9 more), Panama, Colombia, Aruba, Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados, Sint Maarten, Virgin Islands
INSIDE
$7,537
OCEANVIEW
$8,923
BALCONY
$10,656
SUITE
$24,763
From 7,537
View Trip
43 Day Panama Canal & Hawaiian Holiday with Seabourn
Cruise

43 Days (42 Nights) Miami to Los Angeles
Cruise Line: Seabourn
Ship: Sojourn
Departure: 25 November 2025
Countries Visited: USA, Dominican Republic, Curacao, Colombia (+3 more), Costa Rica, Guatemala, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
$21,542
BALCONY
$28,175
SUITE
$51,737
From 21,542
View Trip
52 Day South America Grand Adventure with Princess
Cruise
 (3)

52 Days (51 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Majestic Princess
Departure: 01 December 2024
Countries Visited: USA, Mexico, Panama, Peru (+7 more), Chile, Argentina, Falkland Islands, Uruguay, Brazil, Dominica, Saint Kitts and Nevis
INSIDE
$8,785
OCEANVIEW
-
BALCONY
$12,270
SUITE
$15,586
From 8,785
View Trip
33 Day Caribbean Amazon Culture with Oceania Cruises
Cruise
 (2)

33 Days (32 Nights) Miami to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 21 December 2024
Countries Visited: USA, Mexico, Belize, Honduras (+12 more), Costa Rica, Panama, Colombia, Curacao, Aruba, Saint Lucia, Barbados, Trinidad and Tobago, Brazil, French Guiana, Grenada, Guadeloupe
Exclusive Deal
INSIDE
$14,265
OCEANVIEW
-
BALCONY
$20,373
SUITE
$49,063
Save 2,095
From 14,265
View Trip
20 Day Panama Canal & the Americas with Viking Cruises
Cruise

20 Days (19 Nights) Santiago to New York
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Mar 2026 to Mar 2026
Countries Visited: Chile, Peru, Panama, Jamaica (+1 more), Bahamas
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$17,815
SUITE
$25,735
Save 1,180
From 17,815
View Trip
31 Day Caribbean Shores To Rio's Marvels with Regent Seven Seas
Cruise

31 Days (30 Nights) Miami to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 November 2025
Countries Visited: USA, Mexico, Belize, Honduras (+12 more), Costa Rica, Panama, Colombia, Aruba, Curacao, Bonaire, Grenada, Barbados, Saint Vincent, Trinidad and Tobago, French Guiana, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$25,238
SUITE
$28,930
Save 12,112
From 25,238
View Trip
Results: 151-180 of 203

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South & Central America Cruises

Amazon Cruises Bahamas Cruises Belize Cruises Bermunda Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Colombia Cruises Costa Rica Cruises Ecuador Cruises Falkland Island Cruises Galapagos Cruises Honduras Cruises Mexico Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises South America Cruises USA Cruises

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Cities

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Routes

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Country Routes

Cruises from New Zealand to USA Cruises from Peru to Argentina Cruises from Puerto Rico to USA Cruises from England to Canada Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Spain Cruises from England to USA Cruises from French Polynesia to USA Cruises from New Zealand to Australia Cruises from Panama to USA Cruises from Spain to Brazil Cruises from USA to New Zealand Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to England Cruises from USA to French Polynesia Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

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