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264 Cruises (587 Cruise Departures)
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 01 March 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Bahamas
Inside
$1,220
Oceanview
$1,510
Balcony
$1,750
Suite
$3,221
From
US$1,220
Per Person
View Trip
13 Day Panama Canal Sunfarer with Holland America
Cruise
 (3)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Feb 2026 to Mar 2026
Visit: USA, Bahamas, Curacao, Colombia, Panama, Costa Rica, Cayman Islands
Advantage Fare
Have It All Fare Option
Fare Saver
Inside
$999
Oceanview
$1,999
Balcony
$2,699
Suite
$4,086
From
US$999
Per Person
View Trip
30 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

30 Days (29 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 March 2027
Visit: USA, Jamaica, Colombia, Panama (+4 more), Costa Rica, Honduras, Belize, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$2,913
Oceanview
$3,505
Balcony
$4,485
Suite
-
From
US$2,913
Save 66
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 13 December 2026
Visit: USA, Cayman Islands, Jamaica, Curacao (+7 more), Bonaire, Aruba, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$2,754
Oceanview
$2,987
Balcony
$3,472
Suite
-
From
US$2,754
Save 65
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visit: USA, Mexico, Guatemala, Belize (+5 more), Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,245
Suite
$9,882
From
US$9,245
Save 16,553
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,734
Oceanview
$2,934
Balcony
$4,275
Suite
$6,823
From
US$2,734
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Symphony of the Seas
Departures: Nov 2026 to Aug 2027
Visit: USA, Mexico, Honduras
Bonus Onboard Credit
Exclusive Savings
Inside
$765
Oceanview
$935
Balcony
$977
Suite
$1,698
From
US$765
Save 738
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Feb 2027 to Mar 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Curacao, Bonaire, Aruba, Dominican Republic
Bonus Onboard Credit
Inside
$2,239
Oceanview
$2,425
Balcony
$2,910
Suite
-
From
US$2,239
Per Person
View Trip
19 Day Discover Barbados, Panama & Costa Rica with Emerald Cruises
New ReleaseCruise
 (3)

19 Days (18 Nights) Bridgetown to Panama City
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 06 January 2028
Visit: Barbados, Saint Vincent, Grenada, Bonaire (+4 more), Curacao, Aruba, Colombia, Panama
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
$17,048
Balcony
-
Suite
$21,413
From
US$17,048
Save 17,932
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 12 December 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Aruba, Curacao, Bonaire, Dominican Republic
Bonus Onboard Credit
Exclusive Savings
Inside
$2,682
Oceanview
$2,953
Balcony
$3,487
Suite
-
From
US$2,682
Save 62
Per Person
View Trip
23 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

23 Days (22 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 23 December 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$2,718
Oceanview
$2,970
Balcony
$3,688
Suite
-
From
US$2,718
Save 66
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean Cruise: Cartagena, Aruba & Curacao with Azamara Cruises
Cruise
 (4)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 15 March 2026
Visit: Panama, Colombia, Aruba, Curacao, Bonaire, Dominican Republic, USA
Azamara Always Included
Exclusive Savings
Inside
$2,635
Oceanview
-
Balcony
-
Suite
-
From
US$2,635
Save 54
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Nov 2026 to Mar 2028
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$946
Oceanview
$1,066
Balcony
$1,366
Suite
$3,314
From
US$946
Per Person
View Trip
22 Day Seattle To Miami with Cunard
Cruise
 (13)

22 Days (21 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2026
Visit: USA, Mexico, Guatemala, Panama, Curacao, Aruba
Inside
$1,589
Oceanview
$1,899
Balcony
$2,100
Suite
$5,999
From
US$1,589
Per Person
View Trip
34 Day Seattle To Miami with Cunard
Cruise
 (13)

34 Days (33 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2026
Visit: USA, Mexico, Guatemala, Panama (+8 more), Curacao, Aruba, Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados, Saint Martin, Virgin Islands
Inside
$2,496
Oceanview
$2,999
Balcony
$3,300
Suite
$9,423
From
US$2,496
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Feb 2027 to Mar 2027
Visit: USA, Curacao, Bonaire, Aruba (+7 more), Dominican Republic, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$2,209
Oceanview
$2,396
Balcony
$3,075
Suite
-
From
US$2,209
Per Person
View Trip
21 Day Panama Canal Connoisseur with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Tampa to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 25 March 2026
Visit: USA, Mexico, Belize, Honduras (+7 more), Costa Rica, Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$6,385
Oceanview
$6,918
Balcony
-
Suite
-
From
US$6,385
Save 6,613
Per Person
View Trip
26 Day Epic Caribbean Escape: Barbados to Costa Rica with Emerald Cruises
New ReleaseCruise
 (3)

26 Days (25 Nights) Bridgetown to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 06 January 2028
Visit: Barbados, Saint Vincent, Grenada, Bonaire (+5 more), Curacao, Aruba, Colombia, Panama, Costa Rica
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
$24,098
Balcony
-
Suite
$30,161
From
US$24,098
Save 25,372
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 21 November 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Bonaire, Aruba, Curacao, Dominican Republic
Bonus Onboard Credit
Inside
$2,034
Oceanview
$2,254
Balcony
$2,740
Suite
-
From
US$2,034
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 03 February 2028
Visit: USA, Aruba, Bonaire, Dominican Republic (+7 more), Jamaica, Cayman Islands, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$2,104
Oceanview
$2,324
Balcony
$2,808
Suite
-
From
US$2,104
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 31 October 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Bonaire, Aruba, Dominican Republic, Cayman Islands
Bonus Onboard Credit
Inside
$2,034
Oceanview
$2,254
Balcony
$2,740
Suite
-
From
US$2,034
Per Person
View Trip
33 Day Miami To Seattle with Cunard
Cruise
 (13)

33 Days (32 Nights) Miami to Seattle
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 02 April 2026
Visit: USA, Puerto Rico, Antigua and Barbuda, Saint Lucia (+7 more), Barbados, Saint Martin, Virgin Islands, Colombia, Panama, Costa Rica, Mexico
Inside
$2,399
Oceanview
$2,626
Balcony
$2,999
Suite
$9,756
From
US$2,399
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 09 April 2027
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,843
From
US$10,843
Save 316
Per Person
View Trip
15 Day Caribbean Cruise From New Orleans To New Orleans with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) New Orleans to New Orleans
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 01 February 2026
Visit: USA, Mexico, Honduras, Belize (+5 more), Costa Rica, Panama, Colombia, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,240
From
US$6,240
Save 179
Per Person
View Trip
18 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

18 Days (17 Nights) Los Angeles to Tampa
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 01 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Cayman Islands
Exclusive Savings
Inside
$1,564
Oceanview
$1,945
Balcony
$2,961
Suite
$20,160
From
US$1,564
Save 732
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 14 January 2027
Visit: USA, Curacao, Aruba, Jamaica (+7 more), Cayman Islands, Mexico, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$2,139
Oceanview
$2,328
Balcony
$3,007
Suite
-
From
US$2,139
Per Person
View Trip
11 Day Panama & Pristine Isles with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas, USA
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$3,046
Oceanview
$3,822
Balcony
$4,404
Suite
$6,344
From
US$3,046
Save 3,152
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Oct 2026 to Dec 2027
Visit: USA, Bonaire, Aruba, Curacao (+7 more), Dominican Republic, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$1,934
Oceanview
$2,308
Balcony
$2,643
Suite
-
From
US$1,934
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 22 November 2026
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Curacao, Aruba, Dominican Republic, Cayman Islands
Bonus Onboard Credit
Inside
$2,119
Oceanview
$2,308
Balcony
$2,793
Suite
-
From
US$2,119
Per Person
View Trip
19 Day Discover the Secrets of Panama and Costa Rica with Emerald Cruises
New ReleaseCruise
 (3)

19 Days (18 Nights) San Jose to Bridgetown
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 22 February 2028
Visit: Costa Rica, Panama, Colombia, Aruba (+5 more), Curacao, Bonaire, Grenada, Saint Vincent, Barbados
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
$18,264
Balcony
-
Suite
$22,629
From
US$18,264
Save 19,216
Per Person
View Trip
Results: 151-180 of 264

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South & Central America Cruises

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Travel Styles

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Cities

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Routes

Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Colon to Colon Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Fort Lauderdale to Vancouver Cruises from Galveston to Galveston Cruises from Genoa to Genoa Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from London to Stockholm Cruises from London to Fort Lauderdale Cruises from London to London Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to Boston Cruises from Montreal to Miami Cruises from Montreal to New York Cruises from New Orleans to New Orleans Cruises from New York to New York Cruises from New York to London Cruises from Orlando to Orlando Cruises from Panama City to Miami Cruises from Rome to Miami Cruises from Rome to Athens Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Diego to Fort Lauderdale Cruises from San Diego to Vancouver Cruises from San Diego to San Diego Cruises from San Juan to Miami Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Seattle to Vancouver Cruises from Seattle to Seattle Cruises from Sydney to Honolulu Cruises from Sydney to Sydney Cruises from Tampa to Tampa Cruises from Tokyo to Vancouver Cruises from Vancouver to Vancouver Cruises from Vancouver to Los Angeles Cruises from Vancouver to Honolulu Cruises from Vancouver to Seattle Cruises from Vancouver to San Diego

Country Routes

Cruises from Peru to Argentina Cruises from Germany to England Cruises from Puerto Rico to USA Cruises from Chile to USA Cruises from France to Brazil Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to USA Cruises from France to Italy Cruises from USA to Dominican Republic Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to USA Cruises from Japan to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from Japan to Canada

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

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