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230 Cruises (520 Cruise Departures)
30 Day Holiday Harbors & Hollywood with Oceania Cruises
Cruise

30 Days (29 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 December 2027
Visit: USA, Aruba, Curacao, Bonaire (+11 more), Grenada, Barbados, Saint Lucia, Guadeloupe, Virgin Islands, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,249
Suite
$19,899
From
US$14,249
Save 14,249
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Miami To Los Angeles with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 24 January 2028
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$2,139
Oceanview
$2,889
Balcony
$3,589
Suite
$4,189
From
US$2,139
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$14,649
From
US$14,649
Save 14,649
Per Person
View Trip
16 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Tampa to Los Angeles
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 April 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$4,170
Oceanview
$4,687
Balcony
$8,488
Suite
-
From
US$4,920
Save 1,550
Per Person
View Trip
19 Day Transamerican Treasures with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,899
Suite
$12,099
From
US$6,899
Save 6,899
Per Person
View Trip
17 Day Ultimate Panama Canal Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 24 January 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,749
Suite
$17,599
From
US$16,749
Save 16,749
Per Person
View Trip
181 Day Around The World In 180 Days with Oceania Cruises
Cruise

181 Days (180 Nights) Miami to London
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 06 January 2027
Visit: USA, Cayman Islands, Colombia, Panama (+44 more), Guatemala, Mexico, French Polynesia, Cook Islands, Niue, Tonga, Fiji, Vanuatu, New Caledonia, Australia, Indonesia, Singapore, Thailand, Cambodia, Vietnam, China, South Korea, Japan, Taiwan, Philippines, Malaysia, Sri Lanka, Maldives, India, United Arab Emirates, Qatar, Oman, Saudi Arabia, Egypt, Jordan, Cyprus, Greece, Turkey, Italy, Croatia, Slovenia, Malta, Sicily, Monaco, Spain, Gibraltar, Portugal, France, England
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$88,799
Suite
-
From
US$88,799
Save 88,799
Per Person
View Trip
18 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Bahamas
Inside
$2,359
Oceanview
$3,159
Balcony
$3,909
Suite
$4,509
From
US$2,359
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Seattle to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: USA, Canada, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,099
Oceanview
$2,299
Balcony
$3,399
Suite
$5,999
From
US$2,099
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) New York to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visit: USA, Dominican Republic, Colombia, Panama (+4 more), Costa Rica, Guatemala, Mexico, Canada
Inside
$2,539
Oceanview
$3,339
Balcony
$4,239
Suite
$4,839
From
US$2,539
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 January 2027
Visit: USA, Mexico, Guatemala, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,699
Oceanview
$1,999
Balcony
$3,149
Suite
$4,799
From
US$1,699
Per Person
View Trip
19 Day An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders with Explora Journeys
Cruise

19 Days (18 Nights) Panama City to Vancouver
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA, Canada
Inside
-
Oceanview
-
Balcony
-
Suite
$13,160
From
US$13,160
Per Person
View Trip
8 Day Perfect Day Cococay & West Caribbean with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Icon Of The Seas
Departures: Jun 2026 to Jul 2027
Visit: USA, Mexico, Honduras, Bahamas
Bonus Onboard Credit
Exclusive Savings
Inside
$1,222
Oceanview
$1,502
Balcony
$1,569
Suite
$2,586
From
US$1,222
Save 1,123
Per Person
View Trip
12 Day Pristine islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 April 2027
Visit: Panama, Colombia, Curacao, Saint Vincent, Saint Lucia, Barbados
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,891
Suite
$12,118
From
US$9,891
Save 2,539
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,204
Oceanview
$2,394
Balcony
$3,784
Suite
$6,564
From
US$2,204
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,349
Suite
$11,699
From
US$11,349
Save 11,349
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$2,429
Oceanview
$3,229
Balcony
$4,129
Suite
$4,729
From
US$2,429
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$1,799
Oceanview
$2,049
Balcony
$2,399
Suite
$2,599
From
US$1,799
Per Person
View Trip
15 Day Tropical Treasures with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,299
Suite
$17,999
From
US$17,299
Save 17,299
Per Person
View Trip
15 Day Blue Seas & Pastel Towns with Regent Seven Seas
Cruise

15 Days (14 Nights) Galveston to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 28 December 2026
Visit: USA, Mexico, Belize, Guatemala (+5 more), Honduras, Jamaica, Curacao, Aruba, Bonaire
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,999
Suite
$14,099
From
US$12,999
Save 12,999
Per Person
View Trip
33 Day Around The Americas with Oceania Cruises
Cruise

33 Days (32 Nights) Montreal to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 10 October 2027
Visit: Canada, Bermuda, Bahamas, USA (+6 more), Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,399
Suite
$22,349
From
US$15,399
Save 15,399
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 27 September 2026
Visit: Canada, USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$2,048
Oceanview
$3,096
Balcony
$3,018
Suite
$4,308
From
US$2,048
Per Person
View Trip
29 Day Pan Am 100th Anniversary Legendary Voyage with Holland America
Cruise

29 Days (28 Nights) Miami to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 October 2027
Visit: USA, Bahamas, Jamaica, Dominican Republic (+12 more), Puerto Rico, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Curacao, Aruba, Colombia, Panama, Costa Rica, Belize, Mexico
Book Early & Have It All Fare Option
Inside
$4,179
Oceanview
$4,579
Balcony
$7,079
Suite
$8,859
From
US$4,179
Per Person
View Trip
16 Day Miami To Los Angeles with Cunard
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visit: USA, Colombia, Panama, Guatemala, Mexico
Value Fare
Inside
$3,419
Oceanview
$4,269
Balcony
$4,839
Suite
$9,099
From
US$3,419
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visit: USA, Mexico, Guatemala, Belize (+5 more), Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,849
Suite
$13,799
From
US$12,849
Save 12,849
Per Person
View Trip
128 Day Navigate The World with Regent Seven Seas
Cruise

128 Days (127 Nights) Miami to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 11 January 2027
Visit: USA, Mexico, Belize, Honduras (+32 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama, El Salvador, Guatemala, French Polynesia, American Samoa, Samoa, Fiji, Vanuatu, New Caledonia, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, India, Oman, United Arab Emirates, Qatar, Saudi Arabia, Egypt, Jordan, Israel, Cyprus, Greece, Turkey, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$122,799
From
US$122,799
Save 122,799
Per Person
View Trip
22 Day An Extended Journey from Majestic Horizons to Mayan Gems with Explora Journeys
Cruise

22 Days (21 Nights) Miami to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Visit: USA, Jamaica, Curacao, Aruba (+5 more), Colombia, Panama, El Salvador, Guatemala, Mexico
Inside
-
Oceanview
-
Balcony
-
Suite
$16,560
From
US$16,560
Per Person
View Trip
43 Day Tides To Tahiti with Regent Seven Seas
Cruise

43 Days (42 Nights) Miami to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visit: USA, Mexico, Belize, Honduras (+8 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama, El Salvador, Guatemala, French Polynesia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$40,499
Suite
$41,549
From
US$40,499
Save 40,499
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visit: USA, Bahamas, Colombia, Panama
Inside
-
Oceanview
-
Balcony
-
Suite
$56,695
From
US$56,695
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Enchantment of the Seas
Departure: 17 January 2027
Visit: USA, Honduras, Belize, Mexico
Exclusive Savings
Inside
$460
Oceanview
$580
Balcony
$1,042
Suite
$1,507
From
US$460
Save 292
Per Person
View Trip
Results: 151-180 of 230

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South & Central America Cruises

Amazon Cruises Bahamas Cruises Belize Cruises Bermunda Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Colombia Cruises Costa Rica Cruises Falkland Island Cruises Galapagos Cruises Honduras Cruises Mexico Cruises Panama Cruises Patagonia Cruises South America Cruises USA Cruises

Travel Styles

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Cities

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Routes

Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Cape Town to Cape Town Cruises from Colon to Colon Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Fort Lauderdale to Vancouver Cruises from Fort-de-France to Fort-de-France Cruises from Galveston to Galveston Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from London to Hamburg Cruises from London to Stockholm Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to Boston Cruises from Montreal to Miami Cruises from Montreal to New York Cruises from New Orleans to New Orleans Cruises from New York to New York Cruises from New York to London Cruises from Orlando to Orlando Cruises from Panama City to Miami Cruises from San Diego to Fort Lauderdale Cruises from San Diego to Vancouver Cruises from San Diego to San Diego Cruises from San Francisco to San Francisco Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Seattle to Vancouver Cruises from Seattle to Seattle Cruises from Singapore to Sydney Cruises from Singapore to Hong Kong Cruises from Sydney to Honolulu Cruises from Sydney to Auckland Cruises from Sydney to Sydney Cruises from Tampa to Tampa Cruises from Tokyo to Vancouver Cruises from Vancouver to Vancouver Cruises from Vancouver to Los Angeles Cruises from Vancouver to Honolulu Cruises from Vancouver to Seattle Cruises from Vancouver to San Diego

Country Routes

Cruises from Peru to Argentina Cruises from USA to Germany Cruises from Germany to England Cruises from Puerto Rico to USA Cruises from Japan to China Cruises from Chile to USA Cruises from England to Canada Cruises from England to Germany Cruises from Singapore to China Cruises from Dominican Republic to USA Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to USA Cruises from USA to Dominican Republic Cruises from South Africa to Italy Cruises from Japan to USA Cruises from Panama to USA Cruises from Singapore to Australia Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from USA to Panama Cruises from USA to Peru Cruises from Japan to Canada

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

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