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All Central America Cruises

Whether you want to soak up the sun in Mexico, explore the jungles of Costa Rica, or transit the Panama Canal, you can discover a patchwork of cultures and landscapes on a cruise around Central America. Choose from 589 cruises to Central America traveling with the world's leading cruise lines.
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181 Days
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266 Cruises (589 Cruise Departures)
11 Day Passage To Panama with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 17 January 2026
Visit: USA, Mexico, Belize, Guatemala, Honduras, Costa Rica, Panama
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$3,344
Oceanview
$3,538
Balcony
-
Suite
-
From
US$3,344
Save 3,454
Per Person
View Trip
13 Day World Cruise: Panama Canal To Callao with Seabourn
Cruise
 (1)

13 Days (12 Nights) Miami to Lima
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru
Explore More
Exclusive Savings
Inside
-
Oceanview
$5,284
Balcony
$6,367
Suite
-
From
US$5,284
Per Person
View Trip
11 Day Central American Seas with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 January 2028
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$3,047
Oceanview
$4,017
Balcony
$4,793
Suite
$6,733
From
US$3,047
Save 3,151
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$2,457
Oceanview
$2,687
Balcony
$3,859
Suite
$4,244
From
US$2,457
Per Person
View Trip
21 Day Panama Canal & Pacific Coast with Princess
Cruise
 (6)

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 09 October 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$2,137
Oceanview
$2,437
Balcony
$3,347
Suite
$3,897
From
US$2,137
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 03 April 2027
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Sanctuary Collection
Inside
$1,429
Oceanview
$1,929
Balcony
$3,429
Suite
$5,832
From
US$1,429
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise
 (13)

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Inside
$3,129
Oceanview
$3,629
Balcony
$4,529
Suite
-
From
US$3,129
Per Person
View Trip
8 Day Western Caribbean with Mexico with Princess
Cruise
 (1)

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Princess
Ship: Regal Princess
Departures: Mar 2026 to Mar 2026
Visit: USA, Mexico, Honduras
Princess Standard
Inside
$839
Oceanview
-
Balcony
$885
Suite
$1,099
From
US$839
Per Person
View Trip
13 Day Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 10 February 2028
Visit: Costa Rica, Panama
Fly Free Economy
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$11,200
Balcony
-
Suite
$13,868
From
US$11,200
Save 11,790
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 18 March 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,449
Oceanview
$1,745
Balcony
$2,468
Suite
$3,449
From
US$1,449
Per Person
View Trip
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Champlain, Le Laperouse
Departures: Feb 2026 to Feb 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$6,600
Suite
$11,050
From
US$6,600
Per Person
View Trip
17 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (2)

17 Days (16 Nights) Santiago to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2027 to Mar 2028
Visit: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,259
Oceanview
$2,359
Balcony
$3,259
Suite
$4,986
From
US$2,259
Per Person
View Trip
21 Day Panama Canal - Ocean to Ocean with Princess
Cruise

21 Days (20 Nights) Fort Lauderdale to Seattle
Cruise Line: Princess
Ship: Star Princess
Departure: 13 April 2026
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Princess Premier
Inside
$1,649
Oceanview
$2,009
Balcony
$2,709
Suite
$4,248
From
US$1,649
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$3,228
Oceanview
$3,482
Balcony
$4,090
Suite
$8,580
From
US$3,228
Save 1,755
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2027 to Jan 2028
Visit: USA, Mexico, Belize, Costa Rica, Panama
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$6,299
From
US$3,799
Per Person
View Trip
8 Day Harvest Caye, Cozumel & Roatan with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) New Orleans to New Orleans
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 22 March 2026
Visit: USA, Mexico, Belize, Honduras
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,697
From
US$2,697
Save 72
Per Person
View Trip
11 Day Panama Canal Westward Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Colon to Los Angeles
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 25 April 2026
Visit: Panama, Costa Rica, Mexico, USA
Exclusive Savings
Inside
$824
Oceanview
$955
Balcony
$1,656
Suite
-
From
US$824
Save 395
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas
Departures: Jan 2026 to Oct 2026
Visit: USA, Mexico, Belize, Honduras
Bonus Onboard Credit
Exclusive Savings
Inside
$518
Oceanview
$588
Balcony
$1,095
Suite
$1,291
From
US$518
Save 2,060
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,980
Suite
$10,150
From
US$5,980
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,679
Oceanview
$1,829
Balcony
$2,673
Suite
$3,529
From
US$1,679
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visit: Bahamas, Colombia, Panama
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,263
Suite
$11,475
From
US$10,263
Save 14,827
Per Person
View Trip
8 Day Western Caribbean with Mexico with Princess
Cruise
 (1)

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Princess
Ship: Regal Princess
Departure: 25 January 2026
Visit: USA, Mexico, Belize
Princess Standard
Inside
$499
Oceanview
-
Balcony
$599
Suite
$829
From
US$499
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 12 December 2026
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,349
Oceanview
$1,449
Balcony
$1,949
Suite
$2,899
From
US$1,349
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico
Bonus Onboard Credit
Inside
$1,817
Oceanview
$2,418
Balcony
$3,146
Suite
-
From
US$1,817
Per Person
View Trip
21 Day Seattle to Miami with Silversea
Cruise
 (1)

21 Days (20 Nights) Seattle to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 11 May 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,900
Suite
$19,400
From
US$8,900
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 04 October 2026
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,449
Oceanview
$1,609
Balcony
$2,609
Suite
$4,833
From
US$1,449
Per Person
View Trip
8 Day Western Caribbean with Mexico with Princess
Cruise
 (7)

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Majestic Princess
Departure: 15 March 2026
Visit: USA, Mexico, Honduras, Belize
Princess Standard
Inside
$920
Oceanview
-
Balcony
$1,259
Suite
$1,580
From
US$920
Per Person
View Trip
8 Day Central America - From Miami to Miami with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Aqua, Norwegian Escape
Departures: May 2026 to Nov 2026
Visit: USA, Mexico, Honduras, Belize
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,885
From
US$2,885
Save 97
Per Person
View Trip
19 Day Panama Canal Cruise: Colombia, Costa Rica & Mexico with Azamara Cruises
Cruise
 (4)

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 18 December 2026
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Azamara Always Included
Exclusive Savings
Inside
$4,252
Oceanview
$4,951
Balcony
$5,445
Suite
$9,151
From
US$4,252
Save 77
Per Person
View Trip
19 Day Transamerican Treasures with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,746
Suite
$11,790
From
US$6,746
Save 7,052
Per Person
View Trip
Results: 1-30 of 266

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Country Routes

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Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Ponant Central America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking Central America Cruises Viking South America Cruises

Central America Tours

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