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All Central America Cruises

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280 Cruises (558 Departures)
280 Cruises (558 Departures)
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7 Days
171 Days
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16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$3,038
Oceanview
$3,431
Balcony
$6,268
Suite
-
From (Per Person)
A$3,499
Save 853
Per Person
View Trip
7 Day Western Caribbean with Royal Caribbean
Cruise

7 Days (6 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ships: Icon Of The Seas, Symphony of the Seas
Departures: Aug 2026 to Sep 2027
Visits: USA, Mexico, Honduras
Exclusive Savings
Inside
$1,051
Oceanview
$1,274
Balcony
$1,306
Suite
$2,823
From (Per Person)
A$1,210
Save 825
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visits: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Balcony
-
Suite
$13,817
From (Per Person)
A$13,817
Save 10,193
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Santiago
Cruise Line: Viking
Ship: Viking Octantis
Departure: 06 November 2026
Visits: USA, Mexico, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$14,744
Suite
$21,604
From (Per Person)
A$14,744
Save 1,551
Per Person
View Trip
22 Day An Extended Journey from Majestic Horizons to Mayan Gems with Explora Journeys
Cruise

22 Days (21 Nights) Miami to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Visits: USA, Jamaica, Curacao, Aruba +5 more, Colombia, Panama, El Salvador, Guatemala, Mexico
Exclusive Savings
Suite
$21,246
From (Per Person)
A$21,246
Save 434
Per Person
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Cruise Line: Viking
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visits: USA, Canada, Bahamas, Jamaica +5 more, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$96,035
Suite
$128,375
From (Per Person)
A$96,035
Save 2,020
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visits: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Oceanview
$15,023
Balcony
$16,258
Suite
$35,672
From (Per Person)
A$15,023
Save 6,877
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visits: USA, Mexico, Guatemala, Belize +5 more, Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Balcony
$19,231
Suite
$20,211
From (Per Person)
A$19,231
Save 2,339
Per Person
View Trip
61 Day Bound For Down Under with Oceania Cruises
Cruise

61 Days (60 Nights) Miami to Sydney
Cruise Line: Oceania
Ship: Oceania Vista
Departure: 24 October 2027
Visits: USA, Cayman Islands, Colombia, Panama +11 more, Costa Rica, Guatemala, Mexico, French Polynesia, Cook Islands, Niue, Tonga, Fiji, Vanuatu, New Caledonia, Australia
Your World Inclusions
Exclusive Savings
Balcony
$38,159
Suite
$54,843
From (Per Person)
A$38,159
Save 2,961
Per Person
View Trip
21 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

21 Days (20 Nights) Los Angeles to New York
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica +4 more, Panama, Colombia, Jamaica, Bahamas
Just Cruise Fare
Exclusive Savings
Inside
$4,487
Oceanview
$5,678
Balcony
$6,794
Suite
$7,687
From (Per Person)
A$4,487
Per Person
View Trip
45 Day Sun, Sand & Seas Of Stars with Oceania Cruises
Cruise

45 Days (44 Nights) Los Angeles to Miami
Cruise Line: Oceania
Ship: Oceania Sonata
Departure: 06 January 2028
Visits: USA, Mexico, Guatemala, Costa Rica +14 more, Panama, Colombia, Cayman Islands, Saint Martin, Martinique, Saint Lucia, Grenada, Aruba, Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Guadeloupe, Honduras, Belize
Your World Inclusions
Exclusive Savings
Balcony
$30,241
Suite
$42,395
From (Per Person)
A$30,241
Save 2,749
Per Person
View Trip
12 Day Costa Rica & the Panama Canal with Aurora Expeditions
New ReleaseCruise

12 Days (11 Nights) San Jose to Panama City
Cruise Line: Aurora Expeditions
Ship: Sylvia Earle
Departure: 09 April 2027
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
-
Balcony
$24,448
Suite
$35,833
From (Per Person)
A$24,448
Per Person
View Trip
31 Day Msc World Cruise with MSC Cruises
Cruise

31 Days (30 Nights) Los Angeles to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 07 April 2027
Visits: USA, Mexico, Costa Rica, Panama +6 more, Dominican Republic, Virgin Islands, Saint Martin, Spain, Italy, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$20,922
From (Per Person)
A$20,922
Per Person
View Trip
17 Day Ultimate Panama Canal Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 24 January 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Balcony
$23,789
Suite
$25,279
From (Per Person)
A$23,789
Save 2,431
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visits: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Just Cruise Fare
Exclusive Savings
Inside
$4,455
Oceanview
$5,646
Balcony
$6,987
Suite
$7,880
From (Per Person)
A$4,455
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visits: USA, Bahamas, Colombia, Panama
Exclusive Savings
Balcony
-
Suite
$74,358
From (Per Person)
A$74,358
Save 14,382
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) New York to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visits: USA, Dominican Republic, Colombia, Panama +4 more, Costa Rica, Guatemala, Mexico, Canada
Just Cruise Fare
Exclusive Savings
Inside
$4,751
Oceanview
$5,942
Balcony
$7,283
Suite
$8,176
From (Per Person)
A$4,751
Per Person
View Trip
51 Day MSC World Cruise with MSC Cruises
Cruise

51 Days (50 Nights) Sydney to Rome
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 16 March 2027
Visits: Australia, New Caledonia, Vanuatu, American Samoa +9 more, USA, Mexico, Costa Rica, Panama, Dominican Republic, Virgin Islands, Saint Martin, Spain, Italy
Exclusive Savings
Inside
$12,671
Oceanview
$15,453
Balcony
$19,769
Suite
-
From (Per Person)
A$12,671
Per Person
View Trip
40 Day Vancouver to New York City with Crystal Cruises
New ReleaseCruise

40 Days (39 Nights) Vancouver to New York
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 17 August 2026
Visits: Canada, USA, Mexico, El Salvador +13 more, Costa Rica, Ecuador, Panama, Colombia, Dominican Republic, Puerto Rico, Saint Martin, Dominica, Barbados, Saint Lucia, Antigua and Barbuda, Virgin Islands, Turks and Caicos Islands
Exclusive Savings
Oceanview
$28,220
Balcony
$38,000
Suite
$41,000
From (Per Person)
A$28,220
Save 2,580
Per Person
View Trip
12 Day Pristine islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 April 2027
Visits: Panama, Colombia, Curacao, Saint Vincent, Saint Lucia, Barbados
Exclusive Savings
Balcony
$11,422
Suite
$15,729
From (Per Person)
A$11,422
Save 4,173
Per Person
View Trip
17 Day Panama Canal Coastlines with Oceania Cruises
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Oceania
Ship: Oceania Sonata
Departure: 06 January 2028
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Your World Inclusions
Exclusive Savings
Balcony
$11,592
Suite
$16,452
From (Per Person)
A$11,592
Save 2,288
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Radiance of the Seas
Departures: Aug 2026 to Feb 2027
Visits: USA, Mexico, Belize, Honduras
Exclusive Savings
Inside
$949
Oceanview
$1,020
Balcony
$1,423
Suite
$2,373
From (Per Person)
A$949
Save 607
Per Person
View Trip
16 Day San Diego to Callao (Lima) with Crystal Cruises
New ReleaseCruise

16 Days (15 Nights) San Diego to Lima
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica, Ecuador, Peru
Oceanview
$12,500
Balcony
$14,500
Suite
$17,100
From (Per Person)
A$12,500
Per Person
View Trip
81 Day Arctic to Antarctic Explorer with Viking Cruises
Cruise

81 Days (80 Nights) Nuuk to Buenos Aires
Cruise Line: Viking
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visits: Greenland, Canada, USA, Bahamas +6 more, Jamaica, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$121,123
Suite
$179,335
From (Per Person)
A$121,123
Save 2,660
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visits: Peru, Ecuador, Costa Rica, Panama +4 more, Honduras, Belize, Mexico, USA
Exclusive Savings
Balcony
$13,396
Suite
$13,954
From (Per Person)
A$13,396
Save 11,454
Per Person
View Trip
10 Day Guayaquil to San Juan with Crystal Cruises
New ReleaseCruise

10 Days (9 Nights) Guayaquil to San Juan
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 05 September 2026
Visits: Ecuador, Panama, Colombia, Dominican Republic, Puerto Rico
Exclusive Savings
Oceanview
$6,500
Balcony
$8,600
Suite
$9,050
From (Per Person)
A$6,500
Save 900
Per Person
View Trip
11 Day Fort Lauderdale to Cartagena with Crystal Cruises
New ReleaseCruise

11 Days (10 Nights) Fort Lauderdale to Cartagena
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 22 November 2027
Visits: USA, Mexico, Belize, Guatemala +4 more, Honduras, Costa Rica, Panama, Colombia
Exclusive Savings
Oceanview
$6,112
Balcony
$8,614
Suite
$8,488
From (Per Person)
A$6,112
Save 1,988
Per Person
View Trip
16 Day Fort Lauderdale to San Diego with Crystal Cruises
New ReleaseCruise

16 Days (15 Nights) Fort Lauderdale to San Diego
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 10 June 2028
Visits: USA, Colombia, Panama, Costa Rica, Nicaragua, El Salvador, Mexico
Exclusive Savings
Oceanview
$9,261
Balcony
$11,880
Suite
$11,772
From (Per Person)
A$9,261
Save 1,539
Per Person
View Trip
16 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Tampa to Los Angeles
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 April 2027
Visits: USA, Cayman Islands, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$4,410
Oceanview
$5,488
Balcony
$8,711
Suite
-
From (Per Person)
A$6,921
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: USA, Mexico, Belize, Costa Rica, Panama
Exclusive Savings
Balcony
$5,434
Suite
$8,815
From (Per Person)
A$5,434
Save 1,377
Per Person
View Trip
Results: 211-240 of 280

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South & Central America Cruises

Amazon Cruises Bahamas Cruises Belize Cruises Bermunda Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Colombia Cruises Costa Rica Cruises Falkland Island Cruises Galapagos Cruises Honduras Cruises Mexico Cruises Panama Cruises Patagonia Cruises South America Cruises USA Cruises

Travel Styles

Festivals & Events Luxury Cruises

Cities

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Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to San Juan Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Cape Town to Cape Town Cruises from Cartagena to Cartagena Cruises from Colon to Colon Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Fort Lauderdale to Vancouver Cruises from Fort-de-France to Fort-de-France Cruises from Galveston to Galveston Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Honolulu to Tahiti Cruises from Honolulu to Vancouver Cruises from Lima to Buenos Aires Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Stockholm Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to Boston Cruises from Montreal to Miami Cruises from Montreal to New York Cruises from New Orleans to New Orleans Cruises from New York to New York Cruises from New York to London Cruises from Orlando to Orlando Cruises from Panama City to Miami Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Diego to Fort Lauderdale Cruises from San Diego to Vancouver Cruises from San Diego to San Diego Cruises from San Francisco to San Francisco Cruises from San Juan to Bridgetown Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Seattle to Vancouver Cruises from Seattle to Seattle Cruises from Singapore to Sydney Cruises from Singapore to Hong Kong Cruises from Singapore to Singapore Cruises from Sydney to Honolulu Cruises from Sydney to Auckland Cruises from Sydney to Singapore Cruises from Sydney to Sydney Cruises from Tampa to Tampa Cruises from Tokyo to Vancouver Cruises from Tokyo to Singapore Cruises from Vancouver to Vancouver Cruises from Vancouver to Los Angeles Cruises from Vancouver to Honolulu Cruises from Vancouver to Seattle Cruises from Vancouver to San Diego

Country Routes

Cruises from Peru to Argentina Cruises from Australia to England Cruises from Barbados to Puerto Rico Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from China to Singapore Cruises from Germany to England Cruises from France to Spain Cruises from Puerto Rico to Barbados Cruises from Puerto Rico to USA Cruises from Japan to China Cruises from Chile to USA Cruises from France to Brazil Cruises from England to Canada Cruises from England to Germany Cruises from Singapore to China Cruises from Dominican Republic to USA Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to Singapore Cruises from Australia to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from USA to Dominican Republic Cruises from Italy to Brazil Cruises from Italy to France Cruises from South Africa to Italy Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Japan to Singapore Cruises from Japan to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Singapore to Australia Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain Cruises from Japan to Canada

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

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