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230 Cruises (520 Cruise Departures)
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 24 January 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Cayman Islands, Aruba, Bonaire, Dominican Republic
Inside
$2,285
Oceanview
$2,565
Balcony
$3,155
Suite
$12,741
From
US$2,285
Per Person
View Trip
27 Day Southampton To Los Angeles with Cunard
Cruise
 (1)

27 Days (26 Nights) London to Los Angeles
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 January 2027
Visit: England, USA, Aruba, Panama, El Salvador, Mexico
Bonus Onboard Credit
Value Fare
Inside
$3,049
Oceanview
$4,349
Balcony
$4,849
Suite
$13,899
From
US$3,049
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 27 September 2026
Visit: Canada, USA, Mexico, Guatemala (+4 more), El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,999
Oceanview
$2,199
Balcony
$3,299
Suite
$5,799
From
US$1,999
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,970
Suite
$10,140
From
US$5,970
Per Person
View Trip
143 Day Viking World Cruise with Viking Cruises
Cruise
 (1)

143 Days (142 Nights) Fort Lauderdale to London
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama (+28 more), Costa Rica, French Polynesia, Cook Islands, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Kenya, Tanzania, Madagascar, Mozambique, South Africa, Namibia, Angola, Nigeria, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$65,995
Suite
$119,995
From
US$65,995
Save 3,000
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 13 December 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,399
Oceanview
$1,599
Balcony
$2,199
Suite
$3,749
From
US$1,399
Per Person
View Trip
13 Day World Cruise: Panama Canal To Callao with Seabourn
Cruise
 (1)

13 Days (12 Nights) Miami to Lima
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru
Inside
-
Oceanview
$6,298
Balcony
$7,598
Suite
$16,298
From
US$6,298
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise
 (4)

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 16 January 2028
Visit: USA, Colombia, Panama, El Salvador, Guatemala, Mexico
Book Early & Have It All Fare Option
Inside
$2,634
Oceanview
$2,934
Balcony
$4,734
Suite
$8,934
From
US$2,634
Per Person
View Trip
13 Day Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 10 February 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
$12,525
Balcony
-
Suite
$15,275
From
US$12,525
Per Person
View Trip
8 Day Western Caribbean From New Orleans To New Orleans with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) New Orleans to New Orleans
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Breakaway, Norwegian Getaway
Departures: Nov 2026 to Apr 2028
Visit: USA, Mexico, Honduras, Belize
Inside
$659
Oceanview
$729
Balcony
$979
Suite
$1,029
From
US$659
Per Person
View Trip
43 Day Miami To Buenos Aires Grand Voyage with Azamara Cruises
Cruise
 (5)

43 Days (42 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+9 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Inside
$14,709
Oceanview
$16,609
Balcony
$20,109
Suite
$30,069
From
US$14,709
Per Person
View Trip
18 Day Panama Canal Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 30 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Cayman Islands
Inside
$2,319
Oceanview
$2,889
Balcony
$3,369
Suite
$3,589
From
US$2,319
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Miami To Los Angeles with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departures: Apr 2027 to Apr 2028
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$1,929
Oceanview
$2,379
Balcony
$2,699
Suite
$2,949
From
US$1,929
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (3)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$1,724
Oceanview
$1,984
Balcony
$3,264
Suite
$6,204
From
US$1,724
Per Person
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departures: Jan 2027 to Mar 2027
Visit: USA, Mexico, Belize, Guatemala, Honduras, Costa Rica, Panama
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
$2,880
Oceanview
$3,645
Balcony
$4,455
Suite
$6,165
From
US$2,880
Save 3,683
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 31 October 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Bonaire, Aruba, Dominican Republic, Cayman Islands
Inside
$2,031
Oceanview
$2,251
Balcony
$2,801
Suite
-
From
US$2,031
Per Person
View Trip
22 Day Inca Coast Discovery Segment with Holland America
Cruise
 (3)

22 Days (21 Nights) San Diego to Santiago
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 12 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Ecuador, Peru, Chile
Book Early & Have It All Fare Option
Inside
$2,884
Oceanview
$3,164
Balcony
$4,634
Suite
$7,164
From
US$2,884
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Jan 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$5,640
Suite
$9,550
From
US$5,640
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$6,320
Suite
$10,750
From
US$6,320
Per Person
View Trip
41 Day Buenos Aires To Miami Grand Voyage with Azamara Cruises
Cruise
 (3)

41 Days (40 Nights) Buenos Aires to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica (+7 more), Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Inside
$16,979
Oceanview
$16,979
Balcony
$20,529
Suite
$32,239
From
US$16,979
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visit: USA, Mexico, Panama, Colombia
Inside
$1,939
Oceanview
$2,129
Balcony
$2,794
Suite
$8,974
From
US$1,939
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ships: Emerald Princess, Island Princess, Sapphire Princess
Departures: Nov 2026 to Apr 2028
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,399
Oceanview
$1,599
Balcony
$2,049
Suite
$2,839
From
US$1,399
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 23 February 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$8,290
Suite
$14,020
From
US$8,290
Per Person
View Trip
8 Day Coastal Adventures: Costa Rica & Panama with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) San Jose to Panama City
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 22 February 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
$6,945
Balcony
-
Suite
$8,695
From
US$6,945
Per Person
View Trip
15 Day Panama Canal & Central America with Viking Cruises
Cruise
 (8)

15 Days (14 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2026 to Feb 2028
Visit: USA, Jamaica, Panama, Costa Rica, Honduras, Belize, Mexico
Flights Included
Viking $499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,999
Suite
$7,999
From
US$4,999
Save 1,000
Per Person
View Trip
84 Day Miami To Hong Kong Grand Voyage with Azamara Cruises
Cruise
 (8)

84 Days (83 Nights) Miami to Hong Kong
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 January 2028
Visit: USA, Aruba, Curacao, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand, Australia, Indonesia, Malaysia, Philippines, China
Azamara Always Included
Inside
$29,189
Oceanview
$32,069
Balcony
$36,439
Suite
$53,909
From
US$29,189
Per Person
View Trip
66 Day World Cruise Liner - Africa, Mediterranean & Panama Canal with Princess
Cruise
 (4)

66 Days (65 Nights) Cape Town to Los Angeles
Cruise Line: Princess
Ship: Coral Princess
Departure: 09 March 2028
Visit: South Africa, Namibia, Cape Verde, Spain (+16 more), Gibraltar, Sicily, Greece, Croatia, Montenegro, Turkey, Italy, Corsica, France, Morocco, Portugal, USA, Colombia, Panama, El Salvador, Mexico
Princess Standard
Princess Premier
Inside
$12,049
Oceanview
$12,694
Balcony
$14,119
Suite
$25,029
From
US$12,049
Per Person
View Trip
20 Day Panama Canal Passage with Seabourn
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Inside
-
Oceanview
$8,998
Balcony
$12,898
Suite
$22,498
From
US$8,998
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Emerald Princess
Departure: 24 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,309
Oceanview
$1,549
Balcony
$2,479
Suite
$3,199
From
US$1,309
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (5)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Inside
$26,729
Oceanview
$30,329
Balcony
$36,729
Suite
$53,229
From
US$26,729
Per Person
View Trip
Results: 61-90 of 230

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South & Central America Cruises

Amazon Cruises Bahamas Cruises Belize Cruises Bermunda Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Colombia Cruises Costa Rica Cruises Falkland Island Cruises Galapagos Cruises Honduras Cruises Mexico Cruises Panama Cruises Patagonia Cruises South America Cruises USA Cruises

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Routes

Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Cape Town to Cape Town Cruises from Colon to Colon Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Fort Lauderdale to Vancouver Cruises from Fort-de-France to Fort-de-France Cruises from Galveston to Galveston Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from London to Hamburg Cruises from London to Stockholm Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to Boston Cruises from Montreal to Miami Cruises from Montreal to New York Cruises from New Orleans to New Orleans Cruises from New York to New York Cruises from New York to London Cruises from Orlando to Orlando Cruises from Panama City to Miami Cruises from San Diego to Fort Lauderdale Cruises from San Diego to Vancouver Cruises from San Diego to San Diego Cruises from San Francisco to San Francisco Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Seattle to Vancouver Cruises from Seattle to Seattle Cruises from Singapore to Sydney Cruises from Singapore to Hong Kong Cruises from Sydney to Honolulu Cruises from Sydney to Auckland Cruises from Sydney to Sydney Cruises from Tampa to Tampa Cruises from Tokyo to Vancouver Cruises from Vancouver to Vancouver Cruises from Vancouver to Los Angeles Cruises from Vancouver to Honolulu Cruises from Vancouver to Seattle Cruises from Vancouver to San Diego

Country Routes

Cruises from Peru to Argentina Cruises from USA to Germany Cruises from Germany to England Cruises from Puerto Rico to USA Cruises from Japan to China Cruises from Chile to USA Cruises from England to Canada Cruises from England to Germany Cruises from Singapore to China Cruises from Dominican Republic to USA Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to USA Cruises from USA to Dominican Republic Cruises from South Africa to Italy Cruises from Japan to USA Cruises from Panama to USA Cruises from Singapore to Australia Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from USA to Panama Cruises from USA to Peru Cruises from Japan to Canada

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

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