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249 Cruises (556 Cruise Departures)
17 Day Panama Canal Coastlines with Oceania Cruises
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 January 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,730
Suite
$22,938
From
US$16,730
Save 468
Per Person
View Trip
18 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Bahamas
Exclusive Savings
Inside
$2,308
Oceanview
$3,084
Balcony
$3,812
Suite
$4,394
From
US$2,308
Save 51
Per Person
View Trip
21 Day Panama Canal - Ocean to Ocean with Princess
Cruise

21 Days (20 Nights) Fort Lauderdale to Seattle
Cruise Line: Princess
Ship: Star Princess
Departure: 13 April 2026
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Princess Premier
Inside
$1,799
Oceanview
$2,259
Balcony
$2,299
Suite
$2,399
From
US$1,799
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) Miami to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 11 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Inside
$1,879
Oceanview
$1,899
Balcony
$2,149
Suite
$9,003
From
US$1,879
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 03 April 2027
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Inside
$1,499
Oceanview
$2,199
Balcony
$3,229
Suite
$5,487
From
US$1,499
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Nov 2026 to Mar 2027
Visit: USA, Colombia, Panama, Aruba, Curacao, Bonaire
Exclusive Savings
Inside
$2,354
Oceanview
$2,850
Balcony
$5,483
Suite
$10,330
From
US$2,619
Save 1,336
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 01 April 2028
Visit: USA, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Book Early & Have It All Fare Option
Inside
$2,864
Oceanview
$3,264
Balcony
$4,494
Suite
$7,042
From
US$2,864
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Enchantment of the Seas
Departure: 17 January 2027
Visit: USA, Honduras, Belize, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$519
Oceanview
$619
Balcony
$1,162
Suite
$1,427
From
US$519
Save 318
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visit: Bahamas, Colombia, Panama
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,746
Suite
$13,787
From
US$10,746
Save 749
Per Person
View Trip
8 Day Perfect Day Cococay & West Carib with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Icon Of The Seas
Departures: Mar 2026 to Jul 2027
Visit: USA, Mexico, Honduras, Bahamas
Bonus Onboard Credit
Exclusive Savings
Inside
$1,260
Oceanview
$1,360
Balcony
$1,423
Suite
$2,622
From
US$1,317
Save 1,277
Per Person
View Trip
17 Day Panama Canal - Ocean To Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 10 October 2027
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Inside
$1,399
Oceanview
$1,699
Balcony
$2,299
Suite
$3,449
From
US$1,399
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Miami To Los Angeles with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 24 January 2028
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$2,139
Oceanview
$2,820
Balcony
$3,499
Suite
$4,081
From
US$2,139
Per Person
View Trip
11 Day Panama Canal Westward Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Colon to Los Angeles
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 25 April 2026
Visit: Panama, Costa Rica, Mexico, USA
Exclusive Savings
Inside
$757
Oceanview
$902
Balcony
$1,537
Suite
-
From
US$757
Save 311
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visit: USA, Mexico, Panama, Colombia
Inside
$1,989
Oceanview
$2,179
Balcony
$2,750
Suite
$8,842
From
US$1,989
Per Person
View Trip
23 Day Panama Canal with Holland America
Cruise

23 Days (22 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 01 April 2028
Visit: USA, Colombia, Panama, Costa Rica (+4 more), El Salvador, Guatemala, Mexico, Canada
Book Early & Have It All Fare Option
Inside
$3,409
Oceanview
$3,759
Balcony
$5,132
Suite
$7,680
From
US$3,409
Per Person
View Trip
24 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

24 Days (23 Nights) Fort Lauderdale to Honolulu
Cruise Line: Princess
Ship: Coral Princess
Departure: 06 January 2027
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$3,260
Oceanview
$3,409
Balcony
$5,540
Suite
-
From
US$3,260
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 27 September 2026
Visit: Canada, USA, Mexico, Panama, Aruba
Princess Standard
Inside
$2,088
Oceanview
$2,968
Balcony
$3,338
Suite
$4,594
From
US$2,088
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visit: USA, Bahamas, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$55,132
From
US$55,132
Save 1,563
Per Person
View Trip
19 Day An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders with Explora Journeys
Cruise

19 Days (18 Nights) Panama City to Vancouver
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA, Canada
Inside
-
Oceanview
-
Balcony
-
Suite
$11,760
From
US$11,760
Per Person
View Trip
24 Day Panama Canal & Pacific COast with Princess
Cruise

24 Days (23 Nights) Vancouver to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 03 October 2027
Visit: Canada, USA, Mexico, Panama, Aruba
Princess Standard
Inside
$2,494
Oceanview
$3,116
Balcony
$3,648
Suite
$5,650
From
US$2,494
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 18 March 2028
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,650
Oceanview
$1,869
Balcony
$3,109
Suite
$3,695
From
US$1,650
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica (+4 more), El Salvador, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,534
Oceanview
$2,734
Balcony
$4,076
Suite
$6,820
From
US$2,534
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 27 September 2026
Visit: Canada, USA, Mexico, Guatemala (+4 more), El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$2,234
Oceanview
$2,334
Balcony
$3,634
Suite
$5,844
From
US$2,234
Per Person
View Trip
19 Day Panama Canal Cruise From Miami To San Francisco with Norwegian Cruise Line
Cruise

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 11 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$1,599
Oceanview
$1,849
Balcony
$2,179
Suite
$9,051
From
US$1,599
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Fare Saver
Inside
$2,224
Oceanview
$2,274
Balcony
$4,456
Suite
-
From
US$2,224
Per Person
View Trip
12 Day A Journey Of Mayan Discovery & Mexican Exploration with Explora Journeys
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA
Inside
-
Oceanview
-
Balcony
-
Suite
$6,535
From
US$6,535
Per Person
View Trip
17 Day Panama Canal & Pacific Gems with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 December 2026
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,617
Suite
$16,205
From
US$15,617
Save 16,181
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 January 2027
Visit: USA, Mexico, Guatemala, Panama, Colombia, Bahamas
Fare Saver
Inside
$2,124
Oceanview
$2,324
Balcony
$3,224
Suite
$4,750
From
US$2,124
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,109
Oceanview
$2,209
Balcony
$3,479
Suite
$5,845
From
US$2,109
Per Person
View Trip
19 Day Panama Canal Cruise From Miami To Seattle with Norwegian Cruise Line
Cruise
 (1)

19 Days (18 Nights) Miami to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 25 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$1,499
Oceanview
-
Balcony
$1,969
Suite
$2,348
From
US$1,499
Per Person
View Trip
Results: 61-90 of 249

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Cruise Lines Exploring South & Central America

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