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203 Cruises (488 Cruise Departures)
16 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Panama City
Ship: Norwegian Jade
Departure: 04 January 2025
Countries Visited: USA, Dominican Republic, Puerto Rico, Virgin Islands (+7 more), Saint Lucia, Trinidad and Tobago, Grenada, Aruba, Colombia, Panama, Costa Rica
Free At Sea OfferExclusive Solo Offer
INSIDE
$3,578
OCEANVIEW
$4,079
BALCONY
$5,886
SUITE
$6,311
From 3,578
View Trip
17 Day Southern Caribbean Beauty with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Bridgetown
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 November 2025
Countries Visited: USA, Mexico, Belize, Honduras (+8 more), Costa Rica, Panama, Colombia, Aruba, Curacao, Bonaire, Grenada, Barbados
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,878
SUITE
$15,016
Save 7,062
From 12,878
View Trip
17 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 17 April 2025
Countries Visited: USA, Cayman Islands, Colombia, Panama (+3 more), Costa Rica, Guatemala, Mexico
Exclusive Offer
INSIDE
$3,290
OCEANVIEW
$4,057
BALCONY
$6,225
SUITE
$26,891
Save 4,583
From 3,290
View Trip
17 Day Panama Canal Westward Cruise with Royal Caribbean
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 April 2025
Countries Visited: USA, Cayman Islands, Colombia, Panama (+2 more), Guatemala, Mexico
Exclusive Deal
INSIDE
$3,615
OCEANVIEW
$3,867
BALCONY
$5,687
SUITE
-
Save 1,182
From 3,153
View Trip
11 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Panama City to Tampa
Ship: Norwegian Jade
Departure: 19 January 2025
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
Free At Sea Offer
INSIDE
$2,675
OCEANVIEW
$2,934
BALCONY
$4,316
SUITE
$4,589
From 2,675
View Trip
16 Day Panama Canal Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) Tampa to Los Angeles
Cruise Line: Royal Caribbean
Ship: Radiance of the Seas
Departure: 19 April 2025
Countries Visited: USA, Cayman Islands, Colombia, Panama (+2 more), Guatemala, Mexico
Exclusive Deal
INSIDE
$2,862
OCEANVIEW
$3,230
BALCONY
$4,715
SUITE
-
Save 917
From 2,510
View Trip
22 Day Panama Canal - Tampa with Norwegian Cruise Line
Cruise

22 Days (21 Nights) Seattle to Miami
Ship: Norwegian Encore
Departure: 13 October 2024
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+3 more), Panama, Colombia, Cayman Islands
Free At Sea Offer
INSIDE
$5,111
OCEANVIEW
$5,400
BALCONY
$6,342
SUITE
$6,766
From 5,111
View Trip
12 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Ship: Norwegian Pearl
Departures: Jan 2025 to Jan 2026
Countries Visited: USA, Jamaica, Colombia, Panama (+3 more), Costa Rica, Belize, Mexico
Free At Sea Offer
INSIDE
$3,352
OCEANVIEW
$4,097
BALCONY
$5,798
SUITE
$6,101
From 3,352
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 09 February 2026
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Jamaica
INSIDE
$2,530
OCEANVIEW
$2,611
BALCONY
$3,916
SUITE
$4,688
From 2,530
View Trip
15 Day Caribbean with Norwegian Cruise Line
Cruise

15 Days (14 Nights) New Orleans to New Orleans
Ship: Norwegian Escape
Departure: 22 February 2026
Countries Visited: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Colombia, Jamaica, Cayman Islands
Free At Sea Offer
INSIDE
$3,388
OCEANVIEW
$3,874
BALCONY
$4,527
SUITE
$4,982
From 3,388
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Oct 2025 to Feb 2026
Countries Visited: USA, Mexico, Belize, Honduras
Exclusive Deal
INSIDE
$1,213
OCEANVIEW
$1,308
BALCONY
$2,404
SUITE
$2,475
Save 662
From 1,031
View Trip
11 Day Panama Canal Voyage with Azamara Cruises
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 03 December 2024
Countries Visited: USA, Aruba, Bonaire, Curacao (+2 more), Colombia, Panama
INSIDE
$3,983
OCEANVIEW
$4,345
BALCONY
$5,206
SUITE
$7,506
From 3,983
View Trip
10 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Miami
Ship: Norwegian Gem
Departure: 11 December 2024
Countries Visited: Panama, Costa Rica, Jamaica, Cayman Islands (+3 more), Mexico, Bahamas, USA
Free At Sea Offer
INSIDE
$2,400
OCEANVIEW
$2,703
BALCONY
$3,796
SUITE
$4,010
From 2,400
View Trip
13 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Miami to Lima
Ship: Norwegian Jade
Departure: 27 February 2026
Countries Visited: USA, Colombia, Panama, Ecuador (+1 more), Peru
Free At Sea Offer
INSIDE
$4,245
OCEANVIEW
$4,427
BALCONY
$6,478
SUITE
$6,675
From 4,245
View Trip
21 Day Panama Canal Connoisseur with Oceania Cruises
Cruise

21 Days (20 Nights) Tampa to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 25 March 2026
Countries Visited: USA, Mexico, Belize, Honduras (+7 more), Costa Rica, Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands
Exclusive Deal
INSIDE
$8,894
OCEANVIEW
$9,804
BALCONY
$14,388
SUITE
$20,071
Save 2,056
From 8,894
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 12 April 2025
Countries Visited: USA, Colombia, Costa Rica, Guatemala (+2 more), Mexico, Canada
Have It All Offer
INSIDE
$5,799
OCEANVIEW
$6,353
BALCONY
$7,046
SUITE
$11,689
From 5,799
View Trip
22 Day Panama Canal & Pacific Coast with Princess
Cruise

22 Days (21 Nights) Orlando to Vancouver
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 14 April 2025
Countries Visited: USA, Bahamas, Colombia, Panama (+3 more), Costa Rica, Mexico, Canada
INSIDE
$3,104
OCEANVIEW
$3,374
BALCONY
$4,726
SUITE
$6,737
From 3,104
View Trip
23 Day Tropical Escape Across The Canal with Regent Seven Seas
Cruise

23 Days (22 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 03 January 2026
Countries Visited: USA, Cayman Islands, Jamaica, Bonaire (+7 more), Curacao, Aruba, Colombia, Costa Rica, Panama, Nicaragua, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$19,913
SUITE
$20,942
Save 10,267
From 19,913
View Trip
17 Day Cartagena to Philipsburg with Silversea
Cruise

17 Days (16 Nights) Cartagena to Philipsburg
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 03 February 2026
Countries Visited: Colombia, Aruba, Curacao, Bonaire (+9 more), Saint Vincent, Barbados, Martinique, Dominica, Saint Barthelemy, Virgin Islands, Antigua and Barbuda, Netherlands Antilles, Saint Martin
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,286
BALCONY
$13,662
SUITE
$21,879
From 11,286
View Trip
22 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

22 Days (21 Nights) Seattle to Miami
Ship: Norwegian Joy
Departure: 29 September 2025
Countries Visited: USA, Canada, Mexico, Guatemala (+3 more), Costa Rica, Panama, Colombia
Free At Sea Offer
INSIDE
$5,681
OCEANVIEW
$6,744
BALCONY
$7,351
SUITE
$8,338
From 5,681
View Trip
29 Day Seattle To Miami with Cunard
Cruise
 (8)

29 Days (28 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 September 2025
Countries Visited: USA, Canada, Mexico, Costa Rica (+3 more), Panama, Colombia, Aruba
INSIDE
$5,553
OCEANVIEW
$6,543
BALCONY
$7,929
SUITE
$17,334
From 5,553
View Trip
34 Day Seattle To Miami with Cunard
Cruise
 (8)

34 Days (33 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 25 September 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+8 more), Colombia, Aruba, Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados, Sint Maarten, Virgin Islands
INSIDE
$6,149
OCEANVIEW
$7,238
BALCONY
$8,574
SUITE
$18,623
From 6,149
View Trip
19 Day Andes & South America with Princess
Cruise
 (3)

19 Days (18 Nights) Los Angeles to Santiago
Cruise Line: Princess
Ship: Majestic Princess
Departure: 01 December 2024
Countries Visited: USA, Mexico, Panama, Peru (+1 more), Chile
INSIDE
$2,334
OCEANVIEW
-
BALCONY
$3,057
SUITE
$3,888
From 2,334
View Trip
16 Day Central America Tapestry Voyage with Azamara Cruises
Cruise
 (1)

16 Days (15 Nights) Miami to Lima
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 January 2026
Countries Visited: USA, Mexico, Costa Rica, Panama (+2 more), Ecuador, Peru
INSIDE
$5,382
OCEANVIEW
$6,304
BALCONY
$8,028
SUITE
$11,477
From 5,382
View Trip
39 Day World Cruise Segment - New York to Sydney with Princess
Cruise

39 Days (38 Nights) New York to Sydney
Cruise Line: Princess
Ship: Crown Princess
Departure: 26 July 2026
Countries Visited: USA, Colombia, Ecuador, Peru (+5 more), Easter Island, Pitcairn Islands, French Polynesia, New Zealand, Australia
INSIDE
$8,735
OCEANVIEW
$9,071
BALCONY
$12,843
SUITE
$18,269
From 8,735
View Trip
15 Day Maya & Inca Discovery with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 December 2024
Countries Visited: USA, Mexico, Belize, Honduras (+4 more), Costa Rica, Panama, Ecuador, Peru
Exclusive Deal
INSIDE
$6,213
OCEANVIEW
-
BALCONY
$7,896
SUITE
$11,380
Save 2,037
From 6,213
View Trip
42 Day New York To Sydney with Cunard
Cruise

42 Days (41 Nights) New York to Sydney
Cruise Line: Cunard
Ship: Queen Anne
Departure: 18 January 2025
Countries Visited: USA, Aruba, Panama, Guatemala (+5 more), Mexico, Samoa, Tonga, New Zealand, Australia
INSIDE
$10,636
OCEANVIEW
-
BALCONY
$17,407
SUITE
$31,475
From 10,636
View Trip
51 Day South America Kaleidoscope with Oceania Cruises
Cruise

51 Days (50 Nights) Miami to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 December 2024
Countries Visited: USA, Mexico, Belize, Honduras (+9 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$26,412
SUITE
$38,163
Save 2,198
From 26,412
View Trip
13 Day Fort Lauderdale to Lima with Silversea
Cruise

13 Days (12 Nights) Fort Lauderdale to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 20 January 2025
Countries Visited: Ecuador, Mexico, Panama, Peru (+1 more), USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,791
From 10,791
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Mar 2025 to Mar 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Mexico, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$15,340
SUITE
$22,765
Save 1,160
From 15,340
View Trip
Results: 121-150 of 203

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South & Central America Cruises

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Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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