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264 Cruises (587 Cruise Departures)
11 Day Vivid Western Caribbean with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 April 2026
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$1,980
Oceanview
$2,160
Balcony
$3,120
Suite
$4,236
From
US$1,980
Save 4,618
Per Person
View Trip
8 Day Caribbean Cruise From New Orleans To New Orleans with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) New Orleans to New Orleans
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departures: Mar 2026 to Apr 2026
Visit: USA, Mexico, Belize, Honduras
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,852
From
US$2,852
Save 84
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 13 February 2028
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Aruba, Bonaire, Curacao, Dominican Republic
Bonus Onboard Credit
Inside
$2,154
Oceanview
-
Balcony
$2,856
Suite
-
From
US$2,154
Per Person
View Trip
15 Day Exotic Coasts & Casco Viejo with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 23 February 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,637
Suite
$10,274
From
US$9,637
Save 16,161
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 17 March 2026
Visit: USA, Aruba, Curacao, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,019
Oceanview
$1,150
Balcony
$1,817
Suite
$2,269
From
US$1,019
Per Person
View Trip
29 Day Pan Am 100th Anniversary Legendary Voyage with Holland America
Cruise

29 Days (28 Nights) Miami to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 October 2027
Visit: USA, Bahamas, Jamaica, Dominican Republic (+12 more), Puerto Rico, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Curacao, Aruba, Colombia, Panama, Costa Rica, Belize, Mexico
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,806
Oceanview
$4,296
Balcony
$6,746
Suite
$8,706
From
US$3,806
Per Person
View Trip
26 Day Ultimate Island Holiday with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 19 December 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Barthelemy (+14 more), Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Saint Lucia, Barbados, Grenada, Aruba, Bonaire, Curacao, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,529
Suite
$17,489
From
US$15,529
Save 25,069
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 05 April 2026
Visit: USA, Colombia, Costa Rica, El Salvador, Guatemala, Mexico, Canada
Have It All Fare Option
Inside
$2,599
Oceanview
$2,699
Balcony
$3,499
Suite
$9,634
From
US$2,599
Per Person
View Trip
10 Day Cartagena to Bridgetown with Silversea
Cruise

10 Days (9 Nights) Cartagena to Bridgetown
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 03 February 2026
Visit: Colombia, Aruba, Bonaire, Curacao, Saint Lucia, Saint Vincent, Barbados
All-Inclusive Fare
Inside
-
Oceanview
$6,400
Balcony
$6,900
Suite
$18,720
From
US$6,400
Per Person
View Trip
13 Day Caribbean with Costa Rica & Panama Canal Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Dec 2026 to Dec 2026
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,099
Oceanview
$1,159
Balcony
$1,399
Suite
$2,249
From
US$1,099
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 March 2026
Visit: USA, Jamaica, Aruba, Colombia, Panama, Honduras, Bahamas
Bonus Onboard Credit
Inside
$1,172
Oceanview
$1,362
Balcony
$1,602
Suite
$2,826
From
US$1,172
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 April 2026
Visit: USA, Guatemala, Panama, Curacao, Aruba
Inside
$1,689
Oceanview
$2,039
Balcony
$2,909
Suite
$6,068
From
US$1,689
Per Person
View Trip
12 Day Panama Canal & the Alluring Islands of the Caribbean with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 13 April 2026
Visit: Panama, Colombia, Aruba, Curacao, Saint Vincent, Barbados
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,368
Suite
$12,706
From
US$10,368
Save 16,422
Per Person
View Trip
12 Day Pristine islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 April 2027
Visit: Panama, Colombia, Curacao, Saint Vincent, Saint Lucia, Barbados
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,140
Suite
$12,002
From
US$9,140
Save 16,750
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jewel
Departure: 15 March 2026
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Belize, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,328
From
US$7,328
Save 201
Per Person
View Trip
22 Day An Extended Journey from Majestic Horizons to Mayan Gems with Explora Journeys
Cruise

22 Days (21 Nights) Miami to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Visit: USA, Jamaica, Curacao, Aruba (+5 more), Colombia, Panama, El Salvador, Guatemala, Mexico
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$13,640
Suite
$15,085
From
US$13,640
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,599
Oceanview
$2,799
Balcony
$4,121
Suite
$6,669
From
US$2,599
Per Person
View Trip
11 Day A Journey Through Enchanting Nature & The Marvels Of The Panama Canal with Explora Journeys
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Visit: USA, Jamaica, Curacao, Aruba, Colombia, Panama
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$7,105
Suite
$7,870
From
US$7,105
Per Person
View Trip
34 Day Grand World Voyage with Holland America
Cruise

34 Days (33 Nights) Tokyo to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 14 April 2026
Visit: Japan, USA, Mexico, El Salvador, Panama, Colombia
Advantage Fare
Exclusive Savings
Inside
$5,925
Oceanview
$7,395
Balcony
$15,132
Suite
-
From
US$5,925
Per Person
View Trip
36 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

36 Days (35 Nights) Rome to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2026
Visit: Italy, France, Spain, Portugal (+7 more), Saint Martin, Bahamas, USA, Colombia, Panama, Costa Rica, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$3,237
Oceanview
$3,645
Balcony
$4,363
Suite
-
From
US$3,237
Save 72
Per Person
View Trip
39 Day World Cruise Segment - New York to Sydney with Princess
Cruise
 (6)

39 Days (38 Nights) New York to Sydney
Cruise Line: Princess
Ship: Crown Princess
Departure: 26 July 2026
Visit: USA, Colombia, Ecuador, Peru (+5 more), Easter Island, Pitcairn Islands, French Polynesia, New Zealand, Australia
Princess Standard
Exclusive Savings
Inside
$5,391
Oceanview
-
Balcony
-
Suite
-
From
US$5,391
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (4)

20 Days (19 Nights) Miami to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$6,711
Oceanview
$7,594
Balcony
$9,223
Suite
$13,210
From
US$6,711
Save 148
Per Person
View Trip
32 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (2)

32 Days (31 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2027 to Mar 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,294
Oceanview
$4,494
Balcony
$6,397
Suite
$9,092
From
US$4,294
Per Person
View Trip
32 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (2)

32 Days (31 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2026 to Nov 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+5 more), Peru, Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,869
Oceanview
$4,069
Balcony
$5,599
Suite
$8,245
From
US$3,869
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,900
Suite
$17,000
From
US$17,000
Save 3,000
Per Person
View Trip
37 Day New York To Sydney with Cunard
Cruise
 (1)

37 Days (36 Nights) New York to Sydney
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 January 2027
Visit: USA, Aruba, Panama, El Salvador (+4 more), Mexico, Fiji, New Caledonia, Australia
Inside
$3,969
Oceanview
$5,769
Balcony
$6,219
Suite
-
From
US$3,969
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 22 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
Flights Included
Inside
-
Oceanview
-
Balcony
$10,995
Suite
$16,995
From
US$10,995
Per Person
View Trip
17 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (2)

17 Days (16 Nights) Fort Lauderdale to Santiago
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2026 to Nov 2027
Visit: USA, Cayman Islands, Panama, Ecuador, Peru, Chile
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,059
Oceanview
$2,159
Balcony
$3,059
Suite
$4,692
From
US$2,059
Per Person
View Trip
20 Day Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Azamara Cruises
Cruise
 (3)

20 Days (19 Nights) Santiago to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 March 2027
Visit: Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Exclusive Savings
Inside
$6,446
Oceanview
$7,231
Balcony
$8,075
Suite
$13,410
From
US$6,446
Save 143
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visit: Peru, Ecuador, Costa Rica, Panama (+4 more), Honduras, Belize, Mexico, USA
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,677
Suite
$13,755
From
US$12,677
Save 19,121
Per Person
View Trip
Results: 181-210 of 264

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South & Central America Cruises

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Routes

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Country Routes

Cruises from Peru to Argentina Cruises from Germany to England Cruises from Puerto Rico to USA Cruises from Chile to USA Cruises from France to Brazil Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to USA Cruises from France to Italy Cruises from USA to Dominican Republic Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to USA Cruises from Japan to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from Japan to Canada

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

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