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All Central America Cruises

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230 Cruises (520 Cruise Departures)
15 Day Exotic Coasts & Casco Viejo with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 23 February 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,399
Suite
$13,049
From
US$12,399
Save 12,399
Per Person
View Trip
21 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

21 Days (20 Nights) Los Angeles to New York
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Bahamas
Inside
$2,419
Oceanview
$3,219
Balcony
$3,969
Suite
$4,569
From
US$2,419
Per Person
View Trip
28 Day Southampton To Los Angeles with Cunard
Cruise

28 Days (27 Nights) London to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 11 January 2028
Visit: England, Portugal, USA, Colombia, Panama, Guatemala, Mexico
Value Fare
Inside
$4,919
Oceanview
$6,089
Balcony
$6,979
Suite
$13,599
From
US$4,919
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 04 October 2026
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,559
Oceanview
$2,359
Balcony
$2,329
Suite
$3,549
From
US$1,559
Per Person
View Trip
16 Day Treasures Of Two Oceans with Oceania Cruises
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 06 January 2027
Visit: USA, Cayman Islands, Colombia, Panama, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,649
Suite
$10,499
From
US$6,649
Save 6,649
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$11,800
Balcony
$13,800
Suite
$23,100
From
US$11,800
Per Person
View Trip
8 Day Western Caribbean Holiday Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Radiance of the Seas
Departures: Nov 2026 to Apr 2027
Visit: USA, Mexico, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$459
Oceanview
$597
Balcony
$735
Suite
$1,245
From
US$459
Save 489
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,299
Oceanview
$2,499
Balcony
$3,899
Suite
$6,699
From
US$2,299
Per Person
View Trip
24 Day Panama Canal & Pacific COast with Princess
Cruise

24 Days (23 Nights) Vancouver to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 03 October 2027
Visit: Canada, USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$2,618
Oceanview
-
Balcony
$3,748
Suite
$5,835
From
US$2,618
Per Person
View Trip
11 Day A Journey Through Enchanting Nature & The Marvels Of The Panama Canal with Explora Journeys
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Visit: USA, Jamaica, Curacao, Aruba, Colombia, Panama
Inside
-
Oceanview
-
Balcony
-
Suite
$9,135
From
US$9,135
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$1,624
Oceanview
$1,774
Balcony
$2,964
Suite
$5,644
From
US$1,624
Per Person
View Trip
12 Day A Journey Of Mayan Discovery & Mexican Exploration with Explora Journeys
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA
Inside
-
Oceanview
-
Balcony
-
Suite
$7,280
From
US$7,280
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Nov 2026 to Feb 2027
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$904
Oceanview
$1,103
Balcony
$2,002
Suite
$3,328
From
US$904
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Symphony of the Seas
Departures: Nov 2026 to Apr 2027
Visit: USA, Mexico, Honduras
Bonus Onboard Credit
Exclusive Savings
Inside
$611
Oceanview
$739
Balcony
$733
Suite
$1,813
From
US$611
Save 764
Per Person
View Trip
61 Day Bound For Down Under with Oceania Cruises
Cruise

61 Days (60 Nights) Miami to Sydney
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama (+11 more), Costa Rica, Guatemala, Mexico, French Polynesia, Cook Islands, Niue, Tonga, Fiji, Vanuatu, New Caledonia, Australia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$26,299
Suite
$39,149
From
US$26,299
Save 26,299
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$2,897
Oceanview
$2,943
Balcony
$4,747
Suite
-
From
US$2,897
Save 1,516
Per Person
View Trip
35 Day Hamburg To Rio De Janeiro with Cunard
Cruise

35 Days (34 Nights) Hamburg to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 January 2027
Visit: Germany, Holland, Belgium, England (+5 more), Bermuda, USA, Turks and Caicos Islands, Barbados, Brazil
Bonus Onboard Credit
Value Fare
Inside
$5,369
Oceanview
$7,749
Balcony
$8,769
Suite
$18,599
From
US$5,369
Per Person
View Trip
7 Day Western Caribbean with Royal Caribbean
Cruise

7 Days (6 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ships: Icon Of The Seas, Symphony of the Seas
Departures: Jun 2026 to Sep 2027
Visit: USA, Mexico, Honduras
Bonus Onboard Credit
Exclusive Savings
Inside
$574
Oceanview
$761
Balcony
$739
Suite
$1,959
From
US$574
Save 763
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 01 April 2028
Visit: USA, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Book Early & Have It All Fare Option
Inside
$2,864
Oceanview
$3,264
Balcony
$4,564
Suite
$7,164
From
US$2,864
Per Person
View Trip
17 Day Panama Canal & Pacific Gems with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 December 2026
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,949
Suite
$16,599
From
US$15,949
Save 15,949
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 09 April 2027
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$2,439
Oceanview
$2,839
Balcony
$3,739
Suite
$4,339
From
US$2,439
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Miami to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 02 January 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$1,599
Oceanview
$1,799
Balcony
$2,699
Suite
$4,299
From
US$1,599
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Orlando to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 07 April 2028
Visit: USA, Turks and Caicos Islands, Aruba, Panama, Mexico
Princess Standard
Sanctuary Collection
Inside
$1,999
Oceanview
$2,299
Balcony
$2,799
Suite
$3,749
From
US$1,999
Per Person
View Trip
6 Day Caribbean And Antilles with MSC Cruises
Cruise

6 Days (5 Nights) Galveston to Galveston
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 24 October 2027
Visit: USA, Mexico
Inside
$549
Oceanview
$639
Balcony
$719
Suite
-
From
US$549
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Nov 2026 to Mar 2027
Visit: USA, Colombia, Panama, Aruba, Curacao, Bonaire
Exclusive Savings
Inside
$2,080
Oceanview
$2,895
Balcony
$3,499
Suite
$12,343
From
US$2,272
Save 1,128
Per Person
View Trip
45 Day Sun, Sand & Seas Of Stars with Oceania Cruises
Cruise

45 Days (44 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 January 2028
Visit: USA, Mexico, Guatemala, Costa Rica (+14 more), Panama, Colombia, Cayman Islands, Saint Martin, Martinique, Saint Lucia, Grenada, Aruba, Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Guadeloupe, Honduras, Belize
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,899
Suite
$30,399
From
US$21,899
Save 21,899
Per Person
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visit: USA, Canada, Mexico, Panama (+5 more), Ecuador, Peru, Chile, Argentina, Antarctica
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$52,995
Suite
$75,995
From
US$52,995
Save 2,100
Per Person
View Trip
20 Day Panama Canal & the Americas with Viking Cruises
Cruise

20 Days (19 Nights) Santiago to New York
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Apr 2027 to Apr 2029
Visit: Chile, Peru, Panama, Jamaica, Bahamas
Flights Included
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,295
Suite
$16,495
From
US$11,295
Save 900
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visit: Peru, Ecuador, Costa Rica, Panama (+4 more), Honduras, Belize, Mexico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,099
Suite
$15,999
From
US$15,099
Save 15,099
Per Person
View Trip
13 Day Miami, Fl to Lima (Callao) with Silversea
Cruise

13 Days (12 Nights) Miami to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 January 2028
Visit: USA, Mexico, Costa Rica, Panama, Ecuador, Peru
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$11,100
Suite
$16,900
From
US$11,100
Per Person
View Trip
Results: 181-210 of 230

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South & Central America Cruises

Amazon Cruises Bahamas Cruises Belize Cruises Bermunda Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Colombia Cruises Costa Rica Cruises Falkland Island Cruises Galapagos Cruises Honduras Cruises Mexico Cruises Panama Cruises Patagonia Cruises South America Cruises USA Cruises

Travel Styles

Festivals & Events Luxury Cruises

Cities

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Routes

Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Cape Town to Cape Town Cruises from Colon to Colon Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Fort Lauderdale to Vancouver Cruises from Fort-de-France to Fort-de-France Cruises from Galveston to Galveston Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from London to Hamburg Cruises from London to Stockholm Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to Boston Cruises from Montreal to Miami Cruises from Montreal to New York Cruises from New Orleans to New Orleans Cruises from New York to New York Cruises from New York to London Cruises from Orlando to Orlando Cruises from Panama City to Miami Cruises from San Diego to Fort Lauderdale Cruises from San Diego to Vancouver Cruises from San Diego to San Diego Cruises from San Francisco to San Francisco Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Seattle to Vancouver Cruises from Seattle to Seattle Cruises from Singapore to Sydney Cruises from Singapore to Hong Kong Cruises from Sydney to Honolulu Cruises from Sydney to Auckland Cruises from Sydney to Sydney Cruises from Tampa to Tampa Cruises from Tokyo to Vancouver Cruises from Vancouver to Vancouver Cruises from Vancouver to Los Angeles Cruises from Vancouver to Honolulu Cruises from Vancouver to Seattle Cruises from Vancouver to San Diego

Country Routes

Cruises from Peru to Argentina Cruises from USA to Germany Cruises from Germany to England Cruises from Puerto Rico to USA Cruises from Japan to China Cruises from Chile to USA Cruises from England to Canada Cruises from England to Germany Cruises from Singapore to China Cruises from Dominican Republic to USA Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to New Zealand Cruises from Australia to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to USA Cruises from USA to Dominican Republic Cruises from South Africa to Italy Cruises from Japan to USA Cruises from Panama to USA Cruises from Singapore to Australia Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from USA to Panama Cruises from USA to Peru Cruises from Japan to Canada

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

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