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Cruises from Italy to USA

Are you looking for a cruise from Italy to USA? October is the most popular month to cruise between Italy and USA and there are 39 departures available from twelve of the world's leading cruise lines.
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58 Days
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39 Cruises (39 Cruise Departures)
14 Day Italy & Bermuda Transatlantic with Celebrity Cruises
Cruise

14 Days (13 Nights) Rome to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 31 October 2025
Countries Visited: Italy, Sardinia, Gibraltar, Bermuda (+1 more), USA
Exclusive DealExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,130
SUITE
-
Save (per person) 1,376
From (per person) 2,130
View Trip
23 Day Mediterranean with MSC Cruises
Cruise

23 Days (22 Nights) Naples to Miami
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 25 October 2025
Countries Visited: Italy, France, Spain, Morocco (+5 more), Barbados, Grenada, Sint Maarten, Puerto Rico, USA
Escape To Sea
INSIDE
$1,311
OCEANVIEW
$1,601
BALCONY
$2,111
SUITE
$4,021
From (per person) 1,311
View Trip
57 Day Antiquity To America with Oceania Cruises
Cruise

57 Days (56 Nights) Rome to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 04 October 2025
Countries Visited: Italy, Sicily, Malta, Greece (+12 more), Turkey, Cyprus, Croatia, Montenegro, Tunisia, Spain, Morocco, Portugal, Barbados, Antigua and Barbuda, Puerto Rico, USA
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$21,799
SUITE
-
Save (per person) 21,799
From (per person) 21,799
View Trip
31 Day A Journey Of Sun And Sea with Regent Seven Seas
Cruise

31 Days (30 Nights) Rome to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+7 more), Corsica, Monaco, Spain, Portugal, Bermuda, Bahamas, USA
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$20,499
SUITE
$23,399
Save (per person) 35,899
From (per person) 20,499
View Trip
14 Day Transatlantic Repositioning Cruise From Bologna to Philadelphia with Norwegian Cruise Line
Cruise

14 Days (13 Nights) Bologna to Philadelphia
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 01 November 2026
Countries Visited: Italy, Malta, Sardinia, Spain (+1 more), USA
INSIDE
$1,139
OCEANVIEW
$1,289
BALCONY
$2,189
SUITE
$2,339
From (per person) 1,139
View Trip
15 Day Splendid Atlantic Sojourn with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to New York
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 18 May 2027
Countries Visited: Italy, Spain, Morocco, Bermuda (+1 more), USA
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$9,399
SUITE
$10,299
Save (per person) 15,999
From (per person) 9,399
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Genoa to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 October 2025
Countries Visited: Italy, France, Spain, Portugal (+5 more), Antigua and Barbuda, Sint Maarten, Puerto Rico, USA, Bahamas
Escape To Sea
INSIDE
$1,579
OCEANVIEW
$1,939
BALCONY
$2,069
SUITE
-
From (per person) 1,579
View Trip
15 Day Italy & Bermuda Transatlantic with Celebrity Cruises
Cruise

15 Days (14 Nights) Rome to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 30 October 2026
Countries Visited: Italy, Sardinia, Spain, Portugal (+2 more), Bermuda, USA
Exclusive DealExclusive Solo Offer
INSIDE
$1,472
OCEANVIEW
$1,706
BALCONY
$2,585
SUITE
$13,274
Save (per person) 855
From (per person) 1,472
View Trip
26 Day Europe To The Caribbean with Oceania Cruises
Cruise

26 Days (25 Nights) Rome to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 November 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+6 more), Sardinia, Spain, Portugal, Puerto Rico, Bahamas, USA
Exclusive Deal
INSIDE
$6,599
OCEANVIEW
$8,099
BALCONY
$9,399
SUITE
$12,699
Save (per person) 6,599
From (per person) 6,599
View Trip
Results: 31-39 of 39

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