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Cruises from Florence

Choose from 10 unique cruises starting in Florence, and traveling to Buenos Aires, Miami, Rio de Janeiro, Santos, Valletta and more. April and November are the most popular months to join a cruise from Florence and you can select from 74 departures available from two leading cruise lines.
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10 Cruises (74 Cruise Departures)
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Florence to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 November 2026
Visit: Italy, Sardinia, Sicily, Malta (+6 more), Spain, Gibraltar, Morocco, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$2,189
Oceanview
$2,512
Balcony
$2,764
Suite
$4,132
From
US$2,189
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2027 to Nov 2027
Visit: Italy, France, Spain, Sardinia
Bonus Onboard Credit
Inside
$807
Oceanview
$957
Balcony
$1,047
Suite
$1,767
From
US$807
Per Person
View Trip
25 Day Msc Grand Voyages with MSC Cruises
Cruise

25 Days (24 Nights) Florence to Miami
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 18 October 2026
Visit: Italy, France, Spain, Gibraltar, Morocco, Portugal, USA
Bonus Onboard Credit
Inside
$1,939
Oceanview
$2,289
Balcony
$2,561
Suite
$6,528
From
US$1,939
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Florence to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 14 November 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,749
Oceanview
-
Balcony
-
Suite
-
From
US$1,749
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Feb 2026 to Apr 2026
Visit: Italy, Spain, France
Bonus Onboard Credit
Inside
$574
Oceanview
$700
Balcony
$885
Suite
-
From
US$574
Per Person
View Trip
11 Day Made in Italy, the Luxury Edition with Ponant
Cruise
 (1)

11 Days (10 Nights) Florence to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 September 2027
Visit: Italy, Sicily
Inside
-
Oceanview
$16,120
Balcony
$17,010
Suite
$32,020
From
US$16,120
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Florence to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 14 November 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,449
Oceanview
$1,789
Balcony
$2,059
Suite
$4,807
From
US$1,449
Per Person
View Trip
9 Day Mediterranean with MSC Cruises
Cruise

9 Days (8 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 April 2026
Visit: Italy, Sardinia, Sicily, Malta, Spain, France
Inside
-
Oceanview
-
Balcony
$1,340
Suite
$3,061
From
US$1,340
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: May 2026 to Nov 2026
Visit: Italy, Sardinia, Sicily, Malta, Spain, France
Bonus Onboard Credit
Inside
$927
Oceanview
$1,077
Balcony
$1,147
Suite
$1,624
From
US$927
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Florence to Valletta
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 April 2026
Visit: Italy, Sardinia, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$590
Suite
$820
From
US$590
Per Person
View Trip
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