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Italy Cruises Starting In September 2026, 2027 and 2028

If you're looking at joining a cruise to Italy in September 2026, 2027 or 2028, we have 255 unique cruise itineraries and 3,622 departures available, operated by twenty-three of the world's leading cruise lines departing in September.
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255 Cruises (3,622 Cruise Departures)
7 Day Amalfi Coast Sailing Adventure with Intrepid Travel
Cruise

7 Days (6 Nights) Naples to Procida
Operated By: Intrepid Travel
Departures: May 2026 to Oct 2027
Visit: Italy
Exclusive Savings
From
US$3,088
Save 105
Per Person
View Trip
8 Day Croatian Coast and the Best of the Adriatic with Emerald Cruises
Cruise

8 Days (7 Nights) Venice to Dubrovnik
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia
Departures: Jul 2026 to Oct 2027
Visit: Italy, Croatia
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$6,539
Balcony
-
Suite
$7,695
From
US$6,539
Save 10,607
Per Person
View Trip
8 Day France And Italy with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jul 2026 to Sep 2026
Visit: Italy, France
Inside
$999
Oceanview
$1,209
Balcony
$1,339
Suite
$2,589
From
US$999
Per Person
View Trip
12 Day Epicurean Spotlight On Wine with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 18 September 2026
Visit: Spain, Monaco, Italy
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,116
Suite
$11,292
From
US$10,116
Save 15,882
Per Person
View Trip
8 Day Greek Isles Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Bologna to Bologna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departures: Jul 2026 to Sep 2026
Visit: Italy, Greece
Exclusive Savings
Inside
$1,050
Oceanview
$1,451
Balcony
$1,522
Suite
$1,933
From
US$1,050
Save 631
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece
Bonus Onboard Credit
Inside
$691
Oceanview
$851
Balcony
$1,250
Suite
$1,441
From
US$691
Per Person
View Trip
11 Day Made in Italy, the Luxury Edition with Ponant
Cruise
 (2)

11 Days (10 Nights) Florence to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 September 2027
Visit: Italy, Sicily
Inside
-
Oceanview
$16,120
Balcony
$17,010
Suite
$32,020
From
US$16,120
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: May 2026 to Oct 2027
Visit: Greece, Italy
Bonus Onboard Credit
Inside
$878
Oceanview
$1,148
Balcony
$1,320
Suite
$1,697
From
US$878
Per Person
View Trip
10 Day Exploring Greece and the Adriatic with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Istanbul to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Nov 2026
Visit: Turkey, Greece, Italy
Bonus Onboard Credit
Inside
$1,229
Oceanview
$1,379
Balcony
$1,489
Suite
$2,190
From
US$1,229
Per Person
View Trip
8 Day Greek Isles Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: May 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,179
Oceanview
$1,369
Balcony
$1,419
Suite
$2,116
From
US$1,179
Save 923
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,499
From
US$2,599
Save 800
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$5,299
From
US$3,799
Save 800
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: May 2026 to Oct 2026
Visit: Italy, Spain, France
Bonus Onboard Credit
Exclusive Savings
Inside
$986
Oceanview
$1,126
Balcony
$1,310
Suite
$2,023
From
US$986
Save 50
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: May 2026 to Oct 2026
Visit: Spain, Italy, France
Bonus Onboard Credit
Inside
$867
Oceanview
$987
Balcony
$1,202
Suite
-
From
US$867
Per Person
View Trip
10 Day Venice & the Dalmatian Coast with Tauck
Tour + Cruise

10 Days Venice to Venice
Operated By: Tauck
Ship: Le Boréal
Departure: 09 June 2026
Trip Styles: Coach, Cruise, Island Hopping, Scenic
Visit: Italy, Croatia, Montenegro
Inside
-
Oceanview
$10,990
Balcony
$11,365
Suite
$14,690
From
US$10,990
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Italy, Spain, France
Bonus Onboard Credit
Inside
$1,254
Oceanview
$1,464
Balcony
$1,584
Suite
$2,251
From
US$1,254
Per Person
View Trip
10 Day Europe - Greek Isles & Adriatic with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Trieste to Trieste
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Nov 2026
Visit: Italy, Greece, Turkey
Bonus Onboard Credit
Inside
$1,221
Oceanview
$1,371
Balcony
$1,481
Suite
$2,045
From
US$1,221
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Italy, Corsica, Spain
Inside
$919
Oceanview
$1,019
Balcony
$1,169
Suite
$2,889
From
US$919
Per Person
View Trip
10 Day Mediterranean with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Sep 2026
Visit: Italy, Greece, Turkey
Bonus Onboard Credit
Inside
$1,304
Oceanview
$1,468
Balcony
$1,618
Suite
$1,923
From
US$1,304
Per Person
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2026 to Sep 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,873
Oceanview
$1,974
Balcony
$1,973
Suite
$5,105
From
US$1,873
Save 1,307
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$5,299
From
US$3,799
Save 500
Per Person
View Trip
6 Day An Autumn Escape: Côte d’Azur, Italian Riviera & Corsica with Ponant
Cruise
 (2)

6 Days (5 Nights) Nice to Florence
Cruise Line: Ponant
Ship: Le Boreal
Departure: 28 September 2027
Visit: France, Italy, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Valencia to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 10 September 2026
Visit: Spain, Sardinia, Italy
Inside
$369
Oceanview
$449
Balcony
$589
Suite
$1,069
From
US$369
Per Person
View Trip
8 Day A Journey Of Lush Landscapes & Golden Enchantment with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Athens to Venice
Cruise Line: Explora Journeys
Ship: Explora II
Departures: May 2026 to Oct 2026
Visit: Greece, Croatia, Italy
A Suite Invitation
Sky & Sea
Inside
-
Oceanview
-
Balcony
$5,565
Suite
$6,290
From
US$5,565
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: May 2026 to Oct 2026
Visit: Spain, France, Italy
Bonus Onboard Credit
Inside
$1,003
Oceanview
$1,173
Balcony
$1,303
Suite
$2,223
From
US$1,003
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,760
Suite
$8,592
From
US$5,760
Save 104
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy
Bonus Onboard Credit
Inside
$1,226
Oceanview
$1,436
Balcony
$1,556
Suite
$2,224
From
US$1,226
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy
Bonus Onboard Credit
Inside
$1,256
Oceanview
$1,466
Balcony
$1,586
Suite
$2,253
From
US$1,256
Per Person
View Trip
10 Day Europe - Greek Isles & Adriatic with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Nov 2026
Visit: Italy, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,165
Oceanview
$1,315
Balcony
$1,425
Suite
$1,992
From
US$1,165
Save 54
Per Person
View Trip
11 Day 5th Opera Festival at Sea with Ponant
Cruise
 (1)

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Ships: Le Boreal, Le Bougainville
Departures: Jun 2027 to Sep 2027
Visit: Italy, Sicily, France
Inside
-
Oceanview
$7,870
Balcony
$8,290
Suite
$15,440
From
US$7,870
Per Person
View Trip
Results: 1-30 of 255

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