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Cruises from Rome to Istanbul

Are you looking for a cruise from Rome to Istanbul? May, September and October are the most popular months to cruise between Rome and Istanbul and there are 31 departures available from six of the world's leading cruise lines.
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8 Days
22 Days
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$1,300pp
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13 Cruises (31 Cruise Departures)
Cruise
 (1)

21 Days (20 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Departure: 07 July 2025
Countries Visited: Italy, Sicily, Greece, Albania (+4 more), Montenegro, Croatia, Slovenia, Turkey
Exclusive Deal
INSIDE
$9,203
OCEANVIEW
$10,113
BALCONY
$14,390
SUITE
$19,152
Save 2,067
From 9,203
Cruise
 (1)

12 Days (11 Nights) Rome to Istanbul
Departure: 07 May 2025
Countries Visited: Italy, Egypt, Israel, Cyprus (+2 more), Greece, Turkey
Free At Sea Offer
INSIDE
$4,336
OCEANVIEW
$5,022
BALCONY
$5,708
SUITE
$7,842
From 4,336
Cruise

13 Days (12 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Departure: 04 October 2025
Countries Visited: Italy, Sicily, Malta, Greece (+1 more), Turkey
Exclusive Deal
INSIDE
$6,202
OCEANVIEW
$7,578
BALCONY
$8,637
SUITE
$11,657
Save 2,048
From 6,202
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Departure: 13 May 2024
Countries Visited: Italy, Greece, Turkey
INSIDE
$1,546
OCEANVIEW
$1,615
BALCONY
$2,110
SUITE
-
From 1,546
Cruise

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Viking Cruises
Departures: Dec 2024 to Apr 2026
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,202
SUITE
$13,855
Save 1,933
From 9,202
Cruise

20 Days (19 Nights) Rome to Istanbul
Cruise Line: Princess
Departure: 02 September 2025
Countries Visited: Italy, Montenegro, Greece, Turkey
INSIDE
$5,370
OCEANVIEW
$6,281
BALCONY
$6,974
SUITE
$8,756
From 5,370
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Departure: 12 May 2025
Countries Visited: Italy, Greece, Turkey
INSIDE
$1,358
OCEANVIEW
$1,526
BALCONY
$1,823
SUITE
$3,952
From 1,358
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Cunard
Departure: 15 September 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+3 more), Malta, Spain, Turkey
INSIDE
$4,125
OCEANVIEW
$4,640
BALCONY
$5,550
SUITE
$11,896
From 4,125
Tour + Cruise

19 Days Rome to Istanbul
Operated By: APT
Departure: 04 August 2024
Countries Visited: Italy, Croatia, Montenegro, Greece (+1 more), Turkey
Exclusive DealBonus VIP Deal
Save 1,648
From 17,247
Cruise

12 Days (11 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,468
SUITE
$10,240
Save 2,052
From 6,468
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Viking Cruises
Departures: Aug 2024 to Aug 2026
Countries Visited: Italy, Sicily, Croatia, Montenegro (+2 more), Greece, Turkey
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$14,647
SUITE
$21,478
Save 2,032
From 14,647
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Departure: 21 September 2026
Countries Visited: Italy, Greece, Turkey
INSIDE
$1,684
OCEANVIEW
$1,882
BALCONY
$2,130
SUITE
$4,456
From 1,684
Cruise

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Cunard
Departure: 14 September 2026
Countries Visited: Italy, France, Greece, Turkey
INSIDE
$3,419
OCEANVIEW
$3,865
BALCONY
$4,409
SUITE
$9,409
From 3,419
Results: 13 results

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