Home > Cruises > Europe Cruises > Mediterranean Cruises > Italy > April

Italy Cruises Starting In April 2027, 2028 and 2029

If you're looking at joining a cruise to Italy in April 2027, 2028 or 2029, we have 176 unique cruise itineraries and 2,844 departures available, operated by seventeen of the world's leading cruise lines departing in April.
Filter Results
Departures
Duration
4 Days
23 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$82pp
$65,380pp
Countries
Show More...
Filter Results
176 Cruises (2,844 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Jun 2026 to Oct 2027
Visit: Greece, Italy
Inside
$510
Oceanview
$764
Balcony
$1,094
Suite
$1,337
From
US$510
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Jun 2026 to Oct 2027
Visit: Italy, Greece
Inside
$631
Oceanview
$831
Balcony
$1,231
Suite
$1,427
From
US$631
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Venice to Brindisi
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 April 2027
Visit: Italy, Montenegro
Inside
$279
Oceanview
$349
Balcony
$529
Suite
$629
From
US$279
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Italy, Spain, France
Inside
$452
Oceanview
$612
Balcony
$932
Suite
$1,212
From
US$452
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Spain, France, Italy
Inside
$550
Oceanview
$622
Balcony
$977
Suite
$1,257
From
US$550
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jul 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,699
Suite
$3,499
From
US$2,699
Save 1,250
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Sep 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,999
From
US$3,599
Save 1,000
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Mar 2028
Visit: Greece, Turkey, Italy
Inside
$497
Oceanview
$677
Balcony
$957
Suite
$1,277
From
US$497
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC World Europa
Departures: Oct 2026 to Oct 2027
Visit: Spain, France, Italy
Inside
$1,027
Oceanview
$1,167
Balcony
$1,327
Suite
$2,097
From
US$1,027
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Venice to Ancona
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 10 April 2027
Visit: Italy, Montenegro, Greece
Inside
-
Oceanview
-
Balcony
-
Suite
$1,218
From
US$1,218
Per Person
View Trip
5 Day Cruising the Adriatic with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 06 April 2027
Visit: Italy, Montenegro, Croatia
Inside
$453
Oceanview
$563
Balcony
$783
Suite
$913
From
US$453
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jun 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,999
From
US$3,599
Save 1,200
Per Person
View Trip
8 Day Canary Islands with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Lanzarote to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 05 April 2027
Visit: Spain, Morocco, Italy
Inside
-
Oceanview
$727
Balcony
$1,064
Suite
-
From
US$727
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Oct 2026 to Mar 2028
Visit: Italy, Greece, Turkey
Inside
$463
Oceanview
$643
Balcony
$836
Suite
$1,243
From
US$463
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: France, Italy, Spain
Inside
$457
Oceanview
$633
Balcony
$913
Suite
$1,193
From
US$457
Per Person
View Trip
11 Day Canary Islands with MSC Cruises
Cruise
 (2)

11 Days (10 Nights) Las Palmas de Gran Canaria to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 02 April 2027
Visit: Spain, Morocco, Italy
Inside
-
Oceanview
$1,267
Balcony
$1,397
Suite
-
From
US$1,267
Per Person
View Trip
8 Day Authentic Mediterranean Shores with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 April 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,690
Suite
$10,580
From
US$5,690
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC World Europa
Departures: Oct 2026 to Oct 2027
Visit: Italy, Spain, France
Inside
$1,221
Oceanview
$1,391
Balcony
$1,561
Suite
$2,302
From
US$1,221
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Amalfi to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Jun 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Drinks & WiFi Package
Inside
$688
Oceanview
$858
Balcony
$974
Suite
$1,340
From
US$688
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Jun 2026 to Oct 2027
Visit: Italy, Montenegro, Greece
Inside
$542
Oceanview
$649
Balcony
$1,039
Suite
$1,259
From
US$542
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Ancona to Ancona
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Jun 2026 to Oct 2027
Visit: Italy, Montenegro, Greece
Inside
$590
Oceanview
$734
Balcony
$1,159
Suite
$1,346
From
US$590
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Spain, France, Italy
Inside
$543
Oceanview
$643
Balcony
$963
Suite
$1,243
From
US$543
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Apr 2028
Visit: Spain, France, Italy
Inside
$503
Oceanview
$583
Balcony
$653
Suite
$1,113
From
US$503
Per Person
View Trip
9 Day Mediterranean with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 19 April 2027
Visit: Greece, Turkey, Italy
Inside
$981
Oceanview
$1,107
Balcony
$1,312
Suite
-
From
US$981
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rome to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 23 April 2027
Visit: Italy, Greece, Turkey
Inside
$639
Oceanview
$739
Balcony
$859
Suite
$2,139
From
US$639
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC World Europa
Departures: Oct 2026 to Oct 2027
Visit: Italy, Spain, France
Inside
$1,092
Oceanview
$1,232
Balcony
$1,392
Suite
$2,162
From
US$1,092
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Jun 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Drinks & WiFi Package
Inside
$564
Oceanview
$708
Balcony
$827
Suite
$1,218
From
US$564
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Istanbul to Istanbul
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Mar 2028
Visit: Turkey, Greece, Italy
Inside
$487
Oceanview
$667
Balcony
$905
Suite
$1,267
From
US$487
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Jan 2027 to Apr 2027
Visit: Turkey, Greece, Italy
Inside
$238
Oceanview
$308
Balcony
$428
Suite
$669
From
US$238
Per Person
View Trip
8 Day Mediterranean with Italy & Turkey with Princess
Cruise
 (7)

8 Days (7 Nights) Rome to Athens
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Princess Standard
Princess Premier
Sanctuary Collection
Inside
$909
Oceanview
$1,059
Balcony
$1,404
Suite
$1,699
From
US$909
Per Person
View Trip
Results: 1-30 of 176

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Music Themed Cruises Short Break Cruises

Trip Lengths

1 Month 10 Day 2 Week 3 Day 3 Week 7 Day

Departure Months

May June July August September October November December January February March April

Cities

Amalfi Bari Bologna Florence Genoa Naples Ravenna Rome Trieste Venice

Routes

Athens to Bologna Athens to Rome Athens to Venice Barcelona to Trieste Barcelona to Rome Barcelona to Venice Barcelona to Bologna Bari to Bari Bologna to Barcelona Bologna to Rome Genoa to Genoa Istanbul to Rome Lisbon to Rome London to Rome Miami to Rome Monte Carlo to Rome Ravenna to Ravenna Rome to Trieste Rome to London Rome to Lisbon Rome to Bologna Rome to Miami Rome to Athens Rome to Barcelona Rome to Venice Rome to Monte Carlo Rome to Fort Lauderdale Rome to Istanbul Rome to Rome Trieste to Barcelona Trieste to Rome Trieste to Trieste Trieste to Athens Venice to Venice Venice to Athens Venice to Barcelona Venice to Rome Venice to Istanbul

Country Routes

Brazil to Italy Croatia to Italy England to Italy France to Italy Greece to Italy Italy to England Italy to Croatia Italy to Brazil Italy to France Italy to Greece Italy to Monaco Italy to Portugal Italy to Spain Italy to Turkey Italy to USA Italy to Malta Malta to Italy Portugal to Italy South Africa to Italy Spain to Italy Turkey to Italy United Arab Emirates to Italy USA to Italy

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations