Home > Cruises > Europe Cruises > Mediterranean Cruises > Italy > April

Italy Cruises Starting In April 2026, 2027 and 2028

If you're looking at joining a cruise to Italy in April 2026, 2027 or 2028, we have 215 unique cruise itineraries and 3,554 departures available, operated by nineteen of the world's leading cruise lines departing in April.
Filter Results
Departures
Duration
3 Days
22 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$79pp
$65,380pp
Countries
Show More...
Filter Results
215 Cruises (3,554 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece
Inside
$839
Oceanview
$1,029
Balcony
$1,298
Suite
$1,619
From
US$839
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Venice to Brindisi
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 April 2027
Visit: Italy, Montenegro
Inside
$279
Oceanview
$349
Balcony
$529
Suite
$629
From
US$279
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Inside
-
Oceanview
$469
Balcony
$529
Suite
$819
From
US$469
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Inside
-
Oceanview
-
Balcony
$463
Suite
$923
From
US$463
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: May 2026 to Oct 2027
Visit: Greece, Italy
Bonus Onboard Credit
Drinks, WiFi & Onboard Credit
Inside
$930
Oceanview
$1,127
Balcony
$1,297
Suite
$1,730
From
US$930
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Bari to Athens
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 04 April 2026
Visit: Italy, Greece
Inside
$429
Oceanview
$499
Balcony
$689
Suite
$809
From
US$429
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jan 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,999
From
US$2,599
Save 850
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,999
Suite
$5,999
From
US$3,999
Save 800
Per Person
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Nice
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Sakara
Departures: Apr 2026 to Jul 2027
Visit: Italy, Corsica, Monaco, France
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
Oceanview
$5,982
Balcony
-
Suite
$6,346
From
US$6,346
Save 14,940
Per Person
View Trip
6 Day Greece & Adriatic Sampler with Princess
Cruise
 (1)

6 Days (5 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 10 April 2026
Visit: Italy, Montenegro, Greece
Princess Standard
Inside
$478
Oceanview
-
Balcony
$436
Suite
$448
From
US$436
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Kusadasi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Apr 2026 to Apr 2027
Visit: Italy, Greece, Turkey
Inside
$289
Oceanview
$339
Balcony
$409
Suite
$1,099
From
US$289
Per Person
View Trip
12 Day France Cruise: Monaco, Nice & Marseille with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Rome to Nice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 April 2026
Visit: Italy, Corsica, France, Monaco
Azamara Always Included
Inside
$1,989
Oceanview
$2,339
Balcony
$2,837
Suite
$5,447
From
US$1,989
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 April 2027
Visit: Italy, Montenegro, Croatia
Inside
$712
Oceanview
$842
Balcony
$1,192
Suite
$1,362
From
US$712
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Marseille to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 22 April 2026
Visit: France, Italy, Spain
Inside
$639
Oceanview
-
Balcony
$769
Suite
$1,239
From
US$639
Per Person
View Trip
8 Day Spellbinding Rivieras with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 16 April 2027
Visit: Spain, France, Italy
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,513
Suite
$5,162
From
US$3,513
Save 3,685
Per Person
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Lanzarote to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 13 April 2026
Visit: Spain, Morocco, Italy
Inside
-
Oceanview
-
Balcony
$925
Suite
-
From
US$925
Per Person
View Trip
10 Day Sailing Croatia to Italy with G Adventures
Cruise

10 Days (9 Nights) Zadar to Venice
Operated By: G Adventures
Departures: Apr 2026 to Sep 2026
Visit: Slovenia, Italy, Croatia
Exclusive Savings
From
US$2,017
Save 68
Per Person
View Trip
8 Day Marvelous Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Trieste to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2027
Visit: Italy, Croatia, Greece
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,642
Suite
$4,485
From
US$2,642
Save 2,756
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Dec 2025 to Apr 2027
Visit: France, Italy, Spain
Inside
$599
Oceanview
$669
Balcony
$845
Suite
$1,301
From
US$599
Per Person
View Trip
16 Day The Best of Italy & Greece with Iconic Aegean Islands Cruise with Cosmos
Tour + Cruise

16 Days Venice to Athens
Operated By: Cosmos
Departures: Apr 2026 to Sep 2027
Trip Styles: Coach, Cruise, Island Hopping, Scenic
Visit: Italy, Greece, Turkey
Exclusive Savings
From
US$4,741
Save 438
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Genoa to Valletta
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 19 April 2026
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$609
Suite
-
From
US$609
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Italy, Spain, France
Inside
$1,222
Oceanview
$1,432
Balcony
$1,542
Suite
$2,210
From
US$1,222
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: Italy, Spain, France
Inside
$540
Oceanview
$630
Balcony
$700
Suite
$1,230
From
US$540
Per Person
View Trip
9 Day Canary Islands with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Santa Cruz De Tenerife to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 04 April 2027
Visit: Spain, Morocco, Italy
Inside
$851
Oceanview
$971
Balcony
$1,091
Suite
$1,651
From
US$851
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2026 to Apr 2026
Visit: Italy, Spain, France
Inside
$674
Oceanview
-
Balcony
$770
Suite
$1,083
From
US$674
Per Person
View Trip
6 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Barcelona to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 18 April 2026
Visit: Spain, Italy, France
Inside
-
Oceanview
-
Balcony
$870
Suite
$1,440
From
US$870
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Drinks, WiFi & Onboard Credit
Inside
$831
Oceanview
$975
Balcony
$1,094
Suite
$1,485
From
US$831
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2026 to Apr 2026
Visit: Spain, France, Italy
Inside
$663
Oceanview
$723
Balcony
$828
Suite
$1,138
From
US$663
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (2)

7 Days (6 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 21 April 2026
Visit: Spain, France, Italy
Inside
$768
Oceanview
$852
Balcony
$912
Suite
$1,284
From
US$768
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Dec 2025 to Apr 2027
Visit: Spain, France, Italy
Inside
$513
Oceanview
$594
Balcony
$768
Suite
$1,244
From
US$513
Per Person
View Trip
Results: 1-30 of 215

No results found. Try amending the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Music Themed Cruises Short Break Cruises

Trip Lengths

10 Day 2 Week 3 Day 3 Week 7 Day

Departure Months

December January February March April May June July August September October November

Cities

Amalfi Bari Bologna Genoa Naples Ravenna Rome Trieste Venice

Routes

Athens to Rome Athens to Venice Barcelona to Trieste Barcelona to Rome Barcelona to Venice Barcelona to Bologna Bari to Bari Bologna to Rome Genoa to Genoa Istanbul to Rome Lisbon to Rome Miami to Rome Monte Carlo to Rome Ravenna to Ravenna Rome to Trieste Rome to Lisbon Rome to Bologna Rome to Miami Rome to Athens Rome to Barcelona Rome to Venice Rome to Monte Carlo Rome to Fort Lauderdale Rome to Istanbul Rome to Rome Trieste to Barcelona Trieste to Rome Trieste to Athens Venice to Venice Venice to Athens Venice to Barcelona Venice to Rome Venice to Istanbul

Country Routes

Brazil to Italy Croatia to Italy France to Italy Greece to Italy Italy to Croatia Italy to Brazil Italy to France Italy to Greece Italy to Monaco Italy to Portugal Italy to Spain Italy to Turkey Italy to USA Italy to Malta Malta to Italy Portugal to Italy South Africa to Italy Spain to Italy Turkey to Italy United Arab Emirates to Italy USA to Italy

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2025. Global Journeys. You're viewing our site in US dollars.

    

About Us | View Your Booking | Terms & Conditions | Site Map | We're hiring!

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations