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Italy Cruises Starting In May 2026, 2027 and 2028

If you're looking at joining a cruise to Italy in May 2026, 2027 or 2028, we have 266 unique cruise itineraries and 3,716 departures available, operated by twenty-four of the world's leading cruise lines departing in May.
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266 Cruises (3,716 Cruise Departures)
7 Day Amalfi Coast Sailing Adventure with Intrepid Travel
Cruise

7 Days (6 Nights) Naples to Procida
Operated By: Intrepid Travel
Departures: May 2026 to Oct 2027
Visit: Italy
Exclusive Savings
From
US$2,639
Save 595
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece
Bonus Onboard Credit
Exclusive Savings
Inside
$811
Oceanview
$971
Balcony
$1,291
Suite
$1,561
From
US$811
Save 51
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: May 2026 to Oct 2027
Visit: Greece, Italy
Bonus Onboard Credit
Inside
$930
Oceanview
$1,140
Balcony
$1,320
Suite
$1,730
From
US$930
Per Person
View Trip
6 Day Côte d'Azur & Beyond with Emerald Cruises
New ReleaseCruise

6 Days (5 Nights) Nice to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 21 May 2026
Visit: France, Italy, Monaco
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,541
From
US$11,541
Save 16,249
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Trieste to Athens
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 03 May 2026
Visit: Italy, Greece
Inside
-
Oceanview
-
Balcony
$449
Suite
$1,109
From
US$449
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
$199
Suite
$339
From
US$79
Per Person
View Trip
8 Day The French Riviera Under Le Ponant’s Sails with Ponant
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departures: May 2026 to May 2027
Visit: France, Italy
Inside
-
Oceanview
$10,020
Balcony
$16,130
Suite
$17,960
From
US$10,020
Per Person
View Trip
10 Day Exploring Greece and the Adriatic with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Istanbul to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Nov 2026
Visit: Turkey, Greece, Italy
Bonus Onboard Credit
Inside
$1,338
Oceanview
$1,478
Balcony
$1,548
Suite
$2,247
From
US$1,338
Per Person
View Trip
8 Day Greek Isles Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: May 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,179
Oceanview
$1,369
Balcony
$1,419
Suite
$2,138
From
US$1,179
Save 972
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,499
From
US$2,599
Save 800
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$5,299
From
US$3,799
Save 800
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: May 2026 to Oct 2026
Visit: Italy, Spain, France
Bonus Onboard Credit
Inside
$942
Oceanview
$1,122
Balcony
$1,260
Suite
$1,975
From
US$942
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: May 2026 to Oct 2026
Visit: Spain, Italy, France
Bonus Onboard Credit
Inside
$916
Oceanview
$1,006
Balcony
$1,186
Suite
-
From
US$916
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy
Bonus Onboard Credit
Exclusive Savings
Inside
$1,206
Oceanview
$1,416
Balcony
$1,526
Suite
$2,194
From
US$1,206
Save 57
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$5,299
From
US$3,799
Save 300
Per Person
View Trip
12 Day Italy Intensive Cruise: Bologna, Sicily & Amalfi with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily
Azamara Always Included
Exclusive Savings
Inside
$3,852
Oceanview
$4,424
Balcony
$5,549
Suite
$8,352
From
US$3,852
Save 87
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Oct 2026
Visit: Italy, France, Spain
Bonus Onboard Credit
Inside
$752
Oceanview
$834
Balcony
$1,014
Suite
$1,774
From
US$752
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: France, Italy, Spain
Bonus Onboard Credit
Inside
$1,206
Oceanview
$1,416
Balcony
$1,526
Suite
$2,194
From
US$1,206
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Oct 2026
Visit: France, Spain, Italy
Bonus Onboard Credit
Inside
$689
Oceanview
$819
Balcony
$1,009
Suite
$1,769
From
US$689
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Florence, Nice & Barcelona with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 27 May 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$2,099
Oceanview
$2,347
Balcony
$3,084
Suite
$4,917
From
US$2,099
Per Person
View Trip
8 Day Mediterranean & Aegean with Princess
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 12 May 2026
Visit: Italy, Greece, Turkey
Princess Standard
Inside
$1,149
Oceanview
-
Balcony
$1,612
Suite
$1,899
From
US$1,149
Per Person
View Trip
8 Day Greek Homecoming with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 May 2026
Visit: Italy, Croatia, Greece
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,399
Oceanview
$4,585
Balcony
-
Suite
-
From
US$2,399
Save 2,399
Per Person
View Trip
8 Day Spanish Isles, Rome & Cannes with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 31 May 2026
Visit: Spain, Italy, France
With Love From the World
Inside
$1,441
Oceanview
$1,603
Balcony
$1,673
Suite
$4,263
From
US$1,441
Per Person
View Trip
17 Day Tastes of Italy with Adriatic Coastal Cruise with Travelmarvel
New ReleaseTour + Cruise

17 Days Rome to Dubrovnik
Operated By: Travelmarvel
Ship: MV Princess Eleganza
Departures: Apr 2027 to Sep 2027
Visit: Italy, Slovenia, Croatia
Exclusive Savings
Inside
-
Oceanview
$7,257
Balcony
-
Suite
-
From
US$7,257
Save 164
Per Person
View Trip
10 Day Mediterranean with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Trieste to Trieste
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Sep 2026
Visit: Italy, Greece, Turkey
Bonus Onboard Credit
Inside
$1,280
Oceanview
$1,600
Balcony
$1,480
Suite
$2,180
From
US$1,280
Per Person
View Trip
8 Day Mediterranean & Aegean with Princess
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departures: Apr 2026 to Nov 2027
Visit: Italy, Greece, Turkey
Princess Standard
Inside
$880
Oceanview
$1,491
Balcony
$1,165
Suite
$1,541
From
US$880
Per Person
View Trip
7 Day Amalfi Coast, Cannes & Ibiza with Virgin Voyages
Cruise
 (1)

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 25 May 2026
Visit: Italy, France, Spain
With Love From the World
Inside
$1,633
Oceanview
$1,719
Balcony
$1,947
Suite
-
From
US$1,633
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Barcelona to Bologna
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 08 May 2027
Visit: Spain, Italy, Croatia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,090
Oceanview
$1,233
Balcony
$1,603
Suite
$2,201
From
US$1,090
Save 541
Per Person
View Trip
8 Day Authentic Mediterranean Shores with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2027 to May 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,350
Suite
$9,910
From
US$5,350
Per Person
View Trip
12 Day Rome to Barcelona (Monaco Grand Prix) with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2026
Visit: Italy, Corsica, Monaco, Spain
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,550
Suite
$15,260
From
US$8,550
Per Person
View Trip
Results: 1-30 of 266

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