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Cruises from Istanbul to Rome

Are you looking for a cruise from Istanbul to Rome? October is the most popular month to cruise between Istanbul and Rome and there are 45 departures available from nine of the world's leading cruise lines.
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25 Cruises (45 Cruise Departures)
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: Sep 2026 to Aug 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Just Cruise Fare
Exclusive Savings
Inside
$4,314
Oceanview
$4,745
Balcony
$4,999
Suite
$6,606
From
A$4,314
Per Person
View Trip
15 Day Mediterranean Mosaic with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 27 August 2026
Visit: Turkey, Greece, Croatia, Montenegro, Albania, Sicily, Italy
Your World Inclusions
Exclusive Savings
Inside
$4,210
Oceanview
$4,387
Balcony
$6,952
Suite
$9,254
From
A$4,210
Save 4,380
Per Person
View Trip
12 Day Tales Of The Ancients with Oceania Cruises
Cruise
 (1)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 16 June 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Inclusions
Exclusive Savings
Inside
$4,310
Oceanview
$4,668
Balcony
$7,409
Suite
$10,150
From
A$4,310
Save 2,570
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Exclusive Savings
Inside
$1,981
Oceanview
$2,130
Balcony
$2,526
Suite
$5,199
From
A$1,981
Per Person
View Trip
11 Day Iconic Greek Isles with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 July 2027
Visit: Turkey, Greece, Sicily, Italy
Your World Inclusions
Exclusive Savings
Inside
$4,585
Oceanview
$5,206
Balcony
$7,476
Suite
$10,367
From
A$4,585
Save 2,095
Per Person
View Trip
8 Day Greece, Turkiye And Italy with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 02 June 2028
Visit: Turkey, Greece, Italy
Exclusive Savings
Inside
$2,625
Oceanview
$2,823
Balcony
$3,070
Suite
$6,733
From
A$2,625
Per Person
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 13 October 2027
Visit: Turkey, Greece, Sicily, Italy
Just Cruise Fare
Exclusive Savings
Inside
$4,252
Oceanview
$5,100
Balcony
$5,622
Suite
$6,828
From
A$4,252
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 13 July 2026
Visit: Turkey, Greece, Malta, Sicily, Italy
Just Cruise Fare
Exclusive Savings
Inside
$3,108
Oceanview
$3,406
Balcony
$4,373
Suite
$5,266
From
A$3,108
Per Person
View Trip
8 Day Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy
First Come, First Served Offer
Exclusive Savings
Inside
$2,259
Oceanview
$2,536
Balcony
$2,585
Suite
$5,407
From
A$2,259
Per Person
View Trip
12 Day Tales Of The Ancients with Oceania Cruises
Cruise
 (3)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 October 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Inclusions
Exclusive Savings
Inside
$4,627
Oceanview
$5,975
Balcony
$7,129
Suite
$10,437
From
A$4,627
Save 2,123
Per Person
View Trip
21 Day Revered & Romantic Shores with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 November 2026
Visit: Turkey, Greece, Montenegro, Croatia (+4 more), Italy, Slovenia, Malta, Sicily
Your World Inclusions
Exclusive Savings
Inside
$8,669
Oceanview
$9,271
Balcony
$13,937
Suite
$19,650
From
A$8,669
Save 2,171
Per Person
View Trip
15 Day Ancient Mediterranean Antiquities with Viking Cruises
Cruise
 (3)

15 Days (14 Nights) Istanbul to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+6 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sky, Viking Vela, Viking Vesta
Departures: Nov 2026 to Apr 2028
Visit: Turkey, Greece, Sicily, Italy
Viking Savings Event
Bonus Shipboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,394
Suite
$11,804
From
A$7,394
Save 1,551
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (2)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 05 May 2028
Visit: Turkey, Greece, Sicily, Malta, Italy
Princess Standard
Exclusive Savings
Inside
$2,290
Oceanview
$2,843
Balcony
$2,685
Suite
$3,780
From
A$2,290
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (2)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 17 October 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Princess Standard
Exclusive Savings
Inside
$2,567
Oceanview
$2,843
Balcony
$2,685
Suite
$3,661
From
A$2,567
Per Person
View Trip
15 Day Turkey, Greece & Roman Gems with Seabourn
Cruise
 (1)

15 Days (14 Nights) Istanbul to Rome
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 18 October 2026
Visit: Turkey, Greece, Albania, Italy
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
$11,264
Balcony
$16,845
Suite
$28,007
From
A$11,264
Save 210
Per Person
View Trip
33 Day Ultimate Voyage: Ancient Empires, Adriatic & Amalfi Coast with Scenic
New ReleaseCruise

33 Days (32 Nights) Istanbul to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 12 August 2028
Visit: Turkey, Greece, Montenegro, Croatia, Slovenia, Italy, Sicily
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$63,821
Suite
$69,465
From
A$63,821
Save 17,174
Per Person
View Trip
10 Day Medieval Mediterranean with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,233
Suite
$8,017
From
A$5,233
Save 2,117
Per Person
View Trip
29 Day Yacht Harbor Exploration: From The Aegean To Italy with Seabourn
Cruise

29 Days (28 Nights) Istanbul to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 September 2028
Visit: Turkey, Greece, Italy, Montenegro (+4 more), Croatia, Slovenia, Malta, Sicily
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$28,371
Suite
$46,099
From
A$28,371
Save 518
Per Person
View Trip
8 Day A Journey Through Istanbul's Cosmopolitan Vibrancy to Rome's Timeless Wonders with Explora Journeys
Cruise

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 12 December 2027
Visit: Turkey, Greece, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,840
From
A$6,840
Save 140
Per Person
View Trip
22 Day Yacht Harbors Of Greece & Dalmatian Gems with Seabourn
Cruise

22 Days (21 Nights) Istanbul to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: May 2028 to Jul 2028
Visit: Turkey, Greece, Montenegro, Croatia, Slovenia, Italy, Malta
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,682
Suite
$32,942
From
A$20,682
Save 382
Per Person
View Trip
15 Day President's Cruise with Regent Seven Seas
Cruise

15 Days (14 Nights) Istanbul to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 02 October 2026
Visit: Turkey, Greece, Egypt, Malta, Sicily, Italy
Exquisite Escapes
Single Supplement Special
Exclusive Savings
Inside
-
Oceanview
$10,740
Balcony
$11,599
Suite
$12,416
From
A$10,740
Save 14,930
Per Person
View Trip
19 Day Cradles Of History with Regent Seven Seas
Cruise

19 Days (18 Nights) Istanbul to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 24 September 2028
Visit: Turkey, Greece, Montenegro, Croatia, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$28,776
Suite
$31,158
From
A$28,776
Save 2,524
Per Person
View Trip
13 Day Knights & Emperors with Regent Seven Seas
Cruise

13 Days (12 Nights) Istanbul to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 28 June 2026
Visit: Turkey, Greece, Croatia, Montenegro, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,908
Suite
$21,986
From
A$19,908
Save 2,372
Per Person
View Trip
24 Day Mediterranean Mosaic: Turkey, Greece, Croatia & Italy with Seabourn
Cruise

24 Days (23 Nights) Istanbul to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 May 2027
Visit: Turkey, Greece, Montenegro, Croatia (+4 more), Slovenia, Italy, Malta, Sicily
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$27,186
Suite
-
From
A$27,186
Save 523
Per Person
View Trip
22 Day Adriatic & Mediterranean Sojourn with Viking Cruises
Cruise

22 Days (21 Nights) Istanbul to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+3 more), Viking Mira, Viking Neptune, Viking Vesta
Departures: Mar 2027 to Aug 2028
Visit: Turkey, Greece, Montenegro, Croatia, Sicily, Italy
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,468
Suite
$26,504
From
A$18,468
Save 1,707
Per Person
View Trip
Results: 25 results

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