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Italy Cruises Starting In April 2026, 2027 and 2028

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250 Cruises (3,630 Cruise Departures)
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Valencia to Marseille
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy, France
Inside
$406
Oceanview
$546
Balcony
$676
Suite
$1,246
From
US$406
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy
Inside
$1,226
Oceanview
$1,436
Balcony
$1,556
Suite
$2,286
From
US$1,226
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Oct 2026
Visit: Spain, Italy, France
Inside
$663
Oceanview
$743
Balcony
$973
Suite
$1,733
From
US$663
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Lirica, MSC Orchestra
Departures: Jun 2026 to May 2028
Visit: Turkey, Greece, Italy
Inside
$249
Oceanview
$339
Balcony
$469
Suite
$669
From
US$249
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+10 more), Viking Libra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Jul 2028
Visit: Spain, France, Monaco, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,699
Suite
$3,499
From
US$2,699
Save 1,200
Per Person
View Trip
6 Day Greece & Adriatic Sampler with Princess
Cruise
 (1)

6 Days (5 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 10 April 2026
Visit: Italy, Montenegro, Greece
Princess Standard
Inside
$629
Oceanview
-
Balcony
$971
Suite
$1,435
From
US$629
Per Person
View Trip
6 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Barcelona to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 18 April 2026
Visit: Spain, Italy, France
Inside
-
Oceanview
$671
Balcony
$841
Suite
$1,371
From
US$671
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Oct 2026
Visit: Italy, France, Spain
Inside
$679
Oceanview
$799
Balcony
$1,046
Suite
$1,975
From
US$679
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Italy, Spain, France
Inside
$573
Oceanview
$773
Balcony
$975
Suite
$1,333
From
US$573
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rome to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Apr 2026 to Apr 2027
Visit: Italy, Greece, Turkey
Drinks & WiFi Package
Inside
$624
Oceanview
$734
Balcony
$854
Suite
$1,680
From
US$624
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Kusadasi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 24 April 2026
Visit: Italy, Greece, Turkey
Inside
$249
Oceanview
-
Balcony
$419
Suite
-
From
US$249
Per Person
View Trip
8 Day Authentic Mediterranean Shores with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2027 to May 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,690
Suite
$10,580
From
US$5,690
Per Person
View Trip
8 Day Relaxation & Romance with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 01 April 2028
Visit: Spain, France, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,749
Suite
$5,299
From
US$3,749
Save 3,749
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise

7 Days (6 Nights) Venice to Ancona
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 10 April 2027
Visit: Italy, Montenegro, Greece
Inside
$538
Oceanview
$688
Balcony
$998
Suite
$1,218
From
US$538
Per Person
View Trip
11 Day Riviera Yacht Harbors with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 25 April 2026
Visit: Spain, France, Monaco, Italy
Yours to Explore
Inside
-
Oceanview
-
Balcony
$13,699
Suite
$13,699
From
US$13,699
Per Person
View Trip
8 Day Marvelous Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Trieste to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2027
Visit: Italy, Croatia, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,099
Suite
$5,149
From
US$3,099
Save 3,099
Per Person
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Tour + Cruise

12 Days Malta to Rome
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise

7 Days (6 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 08 April 2027
Visit: Italy, Spain, France
Inside
$731
Oceanview
$881
Balcony
$1,131
Suite
$1,331
From
US$731
Per Person
View Trip
5 Day Cruising the Adriatic with MSC Cruises
Cruise

5 Days (4 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 06 April 2027
Visit: Italy, Montenegro, Croatia
Inside
$453
Oceanview
$613
Balcony
$783
Suite
$913
From
US$453
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 12 April 2027
Visit: France, Italy, Spain
Inside
$850
Oceanview
$1,020
Balcony
-
Suite
$1,540
From
US$850
Per Person
View Trip
8 Day Spellbinding Rivieras with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 16 April 2027
Visit: Spain, France, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$5,599
From
US$3,599
Save 3,599
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Istanbul to Istanbul
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Apr 2028
Visit: Turkey, Greece, Italy
Inside
$522
Oceanview
$702
Balcony
$982
Suite
$1,302
From
US$522
Per Person
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Tour + Cruise

12 Days Rome to Malta
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
16 Day The Best of Italy & Greece with Iconic Aegean Islands Cruise with Cosmos
Tour + Cruise

16 Days Venice to Athens
Operated By: Cosmos
Departures: Apr 2026 to Sep 2027
Trip Styles: Coach, Cruise, Island Hopping, Scenic
Visit: Italy, Greece, Turkey
Single Supplement Waiver
Exclusive Savings
From
US$5,099
Save 300
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Apr 2026 to Oct 2027
Visit: Italy, Montenegro, Greece
Inside
$512
Oceanview
$657
Balcony
$1,082
Suite
$1,269
From
US$512
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Spain, France, Italy
Inside
$616
Oceanview
$791
Balcony
$1,088
Suite
$1,328
From
US$616
Per Person
View Trip
10 Day Sailing Croatia to Italy with G Adventures
Cruise

10 Days (9 Nights) Zadar to Venice
Operated By: G Adventures
Departures: Apr 2026 to Sep 2026
Visit: Slovenia, Italy, Croatia
Exclusive Savings
From
US$1,247
Save 832
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Italy, Spain, France
Inside
$580
Oceanview
$756
Balcony
$1,036
Suite
$1,376
From
US$580
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Apr 2028
Visit: Greece, Turkey, Italy
Inside
$497
Oceanview
$677
Balcony
$957
Suite
$1,277
From
US$497
Per Person
View Trip
8 Day A Journey From Classical Beauty To Cultural Dynamism with Explora Journeys
Cruise

8 Days (7 Nights) Venice to Istanbul
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 April 2026
Visit: Italy, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$4,610
From
US$4,610
Per Person
View Trip
Results: 61-90 of 250

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Cities

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Routes

Athens to Bologna Athens to Rome Athens to Venice Barcelona to Trieste Barcelona to Rome Barcelona to Venice Barcelona to Bologna Bari to Bari Bologna to Rome Genoa to Genoa Istanbul to Venice Istanbul to Rome Lisbon to Rome Miami to Rome Monte Carlo to Rome Ravenna to Ravenna Rome to Trieste Rome to Lisbon Rome to Bologna Rome to Athens Rome to Barcelona Rome to Venice Rome to Monte Carlo Rome to Fort Lauderdale Rome to Istanbul Rome to Rome Trieste to Barcelona Trieste to Rome Trieste to Trieste Trieste to Athens Venice to Venice Venice to Athens Venice to Barcelona Venice to Rome Venice to Istanbul

Country Routes

Brazil to Italy Croatia to Italy France to Italy Greece to Italy Italy to Croatia Italy to Brazil Italy to France Italy to Greece Italy to Monaco Italy to Portugal Italy to Spain Italy to Turkey Italy to USA Italy to Malta Monaco to Italy Portugal to Italy Spain to Italy Turkey to Italy United Arab Emirates to Italy USA to Italy

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