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South America Locally Guided Cruises

Explore the best locally guided tours around South America. Choose from 30 unique cruise itineraries with 9 past traveller reviews from 4 leading cruise lines. October is the most popular month to join a locally guided tour around South America with 161 departures starting between April 2024 and March 2026.
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30 Cruises (161 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 242
From 15,892
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Mar 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Brazil, Argentina, Uruguay, Falkland Islands (+2 more), Chile, Peru
Exclusive Deal
Save 1,544
From 16,860
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33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save 1,546
From 16,955
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26 Day Spirit of South America with Brazil Amazon and Galapagos Cruise with Globus
Tour + Cruise
 (1)

26 Days Manaus to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Oct 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 295
From 18,726
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26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 211
From 13,877
View Trip
17 Day Mysteries of the Inca Empire with a Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Last Chance Deal
Save 197
From 9,871
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12 Day Wonders of the Galápagos & Machu Picchu with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Aug 2024 to Nov 2024
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
Exclusive Solo Offer
From 26,490
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17 Day Peru Splendors with Peru Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Jun 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 187
From 11,675
View Trip
22 Day Spirit of South America with Galapagos Cruise with Globus
Tour + Cruise

22 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Oct 2024 to Nov 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Galapagos (+1 more), Ecuador
Exclusive Savings
Save 258
From 16,345
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Jun 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 165
From 9,934
View Trip
30 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Apr 2025 to Sep 2025
Trip Styles: Coach, Group, Cruise, River Cruise, Island Hopping, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save 2,739
From 39,656
View Trip
25 Day Spirit of South America with Santiago and Galapagos Cruise with Globus
Tour + Cruise

25 Days Santiago to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Nov 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 277
From 17,883
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Northern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Feb 2025 to Nov 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 26,465
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29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
From 15,361
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19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Oct 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 257
From 15,866
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Jun 2024 to Nov 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador
Exclusive Savings
From 12,389
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14 Day Highlights Of South America – Land And Sea Expedition with Hurtigruten
Tour + Cruise

14 Days Colon to Lima
Operated By: Hurtigruten
Ship: MS Fram
Departure: 06 October 2024
Countries Visited: Panama, Ecuador, Peru
Exclusive Deal
INSIDE
$9,655
OCEANVIEW
$10,298
BALCONY
-
SUITE
$22,835
Save 1,179
From 9,655
View Trip
23 Day Legacy of the Incas with Peru Amazon & Galapagos Cruise with Globus
Tour + Cruise

23 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Oct 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 279
From 17,578
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 24,330
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12 Day Wonders of the Galápagos & Machu Picchu: Eastern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Apr 2025 to Oct 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 27,245
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13 Day Patagonia: Edge of the World with Collette
Tour + Cruise

13 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2024 to Mar 2025
Trip Styles: Adventure, Coach, Small Group, Cruise, Scenic
Countries Visited: Argentina, Chile
Exclusive Savings
Save 223
From 10,169
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Aug 2024 to Mar 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 140
From 6,892
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 19,700
View Trip
15 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

15 Days Lima to Quito
Operated By: Collette
Departures: Sep 2024 to Apr 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 192
From 11,213
View Trip
13 Day Highlights of Peru with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador
Exclusive Savings
From 12,301
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Aug 2024 to Nov 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador
Exclusive Savings
From 19,560
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Oct 2024 to Jun 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 179
From 11,704
View Trip
29 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: APT
Ships: Delfin III
Departure: 14 September 2024
Trip Styles: Coach, Group, Cruise, River Cruise, Island Hopping, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 604
From 34,791
View Trip
32 Day Antarctica, Argentina & Brazil with Scenic
Tour + Cruise

32 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2025
Countries Visited: Argentina, Antarctica, South Georgia Island, Falkland Islands (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$45,822
SUITE
$57,999
Save 13,463
From 45,822
View Trip
22 Day Antarctica, Argentina & Brazil with Scenic
Tour + Cruise

22 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 17 February 2025
Countries Visited: Argentina, Antarctica, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$35,551
SUITE
$40,328
Save 4,359
From 35,551
View Trip
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