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All Panama Tours & Cruises

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356 Trips (1,151 Trip Departures)
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 28 March 2027
Visit: USA, Cayman Islands, Jamaica, Costa Rica, Panama, Aruba, Dominican Republic
Princess Standard
Inside
$949
Oceanview
$1,099
Balcony
$1,349
Suite
$1,749
From
US$949
Per Person
View Trip
13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise
 (3)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 08 November 2026
Visit: USA, Bahamas, Aruba, Colombia, Panama, Costa Rica, Jamaica
Fare Saver
Inside
$1,219
Oceanview
$1,419
Balcony
$2,019
Suite
$4,154
From
US$1,219
Per Person
View Trip
20 Day Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Azamara Cruises
Cruise
 (3)

20 Days (19 Nights) Santiago to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 March 2027
Visit: Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Exclusive Savings
Inside
$6,446
Oceanview
$7,231
Balcony
$8,075
Suite
$13,410
From
US$6,446
Save 143
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sun
Departures: Nov 2026 to Nov 2026
Visit: USA, Bahamas, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Inside
$1,799
Oceanview
$1,859
Balcony
$2,528
Suite
$3,769
From
US$1,799
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (4)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Exclusive Savings
Inside
$5,994
Oceanview
$6,459
Balcony
$7,323
Suite
$12,017
From
US$5,994
Save 135
Per Person
View Trip
29 Day Seattle To Miami with Cunard
Cruise
 (13)

29 Days (28 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2026
Visit: USA, Canada, Mexico, Guatemala, Panama, Curacao, Aruba
Inside
$2,499
Oceanview
$3,039
Balcony
$3,909
Suite
$10,133
From
US$2,499
Per Person
View Trip
17 Day Halcyon Holidays with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 19 December 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,485
Suite
$11,589
From
US$8,485
Save 8,913
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,534
Oceanview
$2,734
Balcony
$4,079
Suite
$6,823
From
US$2,534
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$3,815
Oceanview
$4,155
Balcony
$5,068
Suite
-
From
US$3,815
Save 2,198
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Nov 2027 to Mar 2028
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands, Mexico
Princess Standard
Inside
$1,249
Oceanview
$1,449
Balcony
$1,849
Suite
$2,749
From
US$1,249
Per Person
View Trip
21 Day Panama Canal & Pacific Coast with Princess
Cruise
 (6)

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 09 October 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,952
Oceanview
$2,212
Balcony
$2,927
Suite
$4,825
From
US$1,952
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

25 Days (24 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia, Cayman Islands, Jamaica
Bonus Onboard Credit
Exclusive Savings
Inside
$2,328
Oceanview
$2,638
Balcony
$3,502
Suite
-
From
US$2,328
Save 51
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 02 December 2027
Visit: USA, Dominican Republic, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,149
Oceanview
$1,410
Balcony
$1,449
Suite
$1,749
From
US$1,149
Per Person
View Trip
23 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

23 Days (22 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 23 December 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$2,718
Oceanview
$2,970
Balcony
$3,688
Suite
-
From
US$2,718
Save 66
Per Person
View Trip
11 Day Panama To Caribbean Joy with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 January 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Cayman Islands, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,996
Oceanview
-
Balcony
$4,597
Suite
$6,343
From
US$2,996
Save 3,102
Per Person
View Trip
16 Day Antilles To Andes with Oceania Cruises
Cruise
 (1)

16 Days (15 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia, Panama, Ecuador, Peru
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,600
Oceanview
$3,765
Balcony
$5,166
Suite
$7,310
From
US$3,600
Save 4,998
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise
 (3)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 02 October 2026
Visit: USA, Mexico, Guatemala, El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,719
Oceanview
$1,819
Balcony
$2,909
Suite
$4,999
From
US$1,719
Per Person
View Trip
13 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (2)

13 Days (12 Nights) Fort-de-France to Colon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 07 December 2026
Visit: Martinique, Guadeloupe, Saint Lucia, Saint Vincent, Holland, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$8,960
Suite
$14,210
From
US$8,960
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) Miami to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 11 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Inside
$1,899
Oceanview
$2,129
Balcony
$2,099
Suite
$2,299
From
US$1,899
Per Person
View Trip
34 Day Sydney To Miami with Cunard
Cruise
 (13)

34 Days (33 Nights) Sydney to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 25 March 2028
Visit: Australia, Tonga, USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$6,927
Oceanview
$8,115
Balcony
$10,095
Suite
$23,856
From
US$6,927
Per Person
View Trip
13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise
 (3)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departures: Oct 2026 to Mar 2027
Visit: USA, Bahamas, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Fare Saver
Inside
$1,219
Oceanview
$1,419
Balcony
$2,019
Suite
$4,154
From
US$1,219
Per Person
View Trip
36 Day World Cruise: Panama Canal Crossing & Polynesia with Seabourn
Cruise
 (1)

36 Days (35 Nights) Miami to Tahiti
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru, Chile, Easter Island, French Polynesia
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,962
Suite
$35,767
From
US$17,962
Save 286
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 March 2026
Visit: USA, Jamaica, Aruba, Colombia, Panama, Honduras, Bahamas
Bonus Onboard Credit
Inside
$1,092
Oceanview
$1,282
Balcony
$1,522
Suite
$2,826
From
US$1,092
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (3)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$2,194
Oceanview
$2,394
Balcony
$3,583
Suite
$6,307
From
US$2,194
Per Person
View Trip
15 Day Panama Canal To Machu Picchu with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia, Panama, Ecuador, Peru
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$4,221
Oceanview
$4,609
Balcony
$6,064
Suite
$8,586
From
US$4,221
Save 4,377
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 01 March 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Bahamas
Inside
$749
Oceanview
$1,039
Balcony
$1,279
Suite
$3,222
From
US$749
Per Person
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 March 2028
Visit: USA, Cayman Islands, Jamaica, Aruba, Curacao, Colombia, Panama
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,949
Oceanview
$3,919
Balcony
$4,695
Suite
$6,732
From
US$2,949
Save 3,049
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 17 March 2026
Visit: USA, Aruba, Curacao, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,128
Oceanview
$1,131
Balcony
-
Suite
-
From
US$1,128
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Exclusive Savings
Inside
$2,337
Oceanview
$2,948
Balcony
$3,074
Suite
$4,093
From
US$2,337
Save 52
Per Person
View Trip
28 Day Southampton To Los Angeles with Cunard
Cruise

28 Days (27 Nights) London to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 11 January 2028
Visit: England, Portugal, USA, Colombia, Panama, Guatemala, Mexico
Inside
$5,389
Oceanview
$6,637
Balcony
$8,023
Suite
$15,646
From
US$5,389
Per Person
View Trip
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