Home > Tours > Latin America Tours > Central America Tours > Panama Tours & Cruises > All Trips

All Panama Tours & Cruises

Filter Results
373 Trips (1,258 Departures)
373 Trips (1,258 Departures)
Departures
Show More...
Duration
6 Days
171 Days
Types
Budget
Start & End Cities
Operators
Show More...
Price
$1,000pp
$147,495pp
Countries
Show More...
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Island Princess
Departures: Mar 2027 to Apr 2027
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,350
Oceanview
$2,631
Balcony
$3,750
Suite
$5,829
From (Per Person)
A$2,350
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 12 December 2027
Visits: USA, Jamaica, Colombia, Panama +7 more, Costa Rica, Honduras, Belize, Aruba, Curacao, Bonaire, Dominican Republic
Exclusive Savings
Inside
$4,686
Oceanview
$5,092
Balcony
$5,924
Suite
-
From (Per Person)
A$4,686
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 13 February 2028
Visits: USA, Jamaica, Colombia, Panama +7 more, Costa Rica, Honduras, Belize, Aruba, Bonaire, Curacao, Dominican Republic
Exclusive Savings
Inside
$3,786
Oceanview
-
Balcony
$4,934
Suite
-
From (Per Person)
A$3,786
Per Person
View Trip
13 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (2)

13 Days (12 Nights) Miami to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Sun
Departures: Jan 2027 to Feb 2027
Visits: USA, Cayman Islands, Jamaica, Colombia +4 more, Panama, Costa Rica, Belize, Mexico
Just Cruise Fare
Exclusive Savings
Inside
$1,919
Oceanview
$2,437
Balcony
$4,077
Suite
$4,506
From (Per Person)
A$1,919
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 10 April 2027
Visits: Panama, Colombia, Aruba, Bonaire, Curacao
Exclusive Savings
Inside
$1,690
Oceanview
$1,835
Balcony
$4,257
Suite
$3,313
From (Per Person)
A$1,690
Save 1,182
Per Person
View Trip
76 Day America And Caribbean Discovery with P&O Cruises Worldwide
Cruise
 (1)

76 Days (75 Nights) London to London
Operator: P&O Cruises Worldwide
Ship: Aurora
Departure: 03 January 2027
Visits: England, Portugal, Saint Martin, Antigua and Barbuda +23 more, Dominica, Saint Vincent, Grenada, Trinidad and Tobago, Holland, Curacao, Colombia, Panama, Costa Rica, Honduras, Mexico, Cayman Islands, USA, Bahamas, Turks and Caicos Islands, Dominican Republic, Jamaica, Virgin Islands, Saint Kitts and Nevis, Guadeloupe, Martinique, Saint Lucia, Barbados
Bonus Onboard Spend
Exclusive Savings
Inside
$17,035
Oceanview
$22,745
Balcony
$34,303
Suite
$73,074
From (Per Person)
A$17,035
Per Person
View Trip
21 Day Panama Canal Navigator with Oceania Cruises
Cruise
 (4)

21 Days (20 Nights) Miami to Miami
Operator: Oceania
Ship: Oceania Marina
Departure: 05 March 2027
Visits: USA, Mexico, Belize, Guatemala +8 more, Honduras, Costa Rica, Panama, Colombia, Aruba, Curacao, Jamaica, Cayman Islands
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,164
Suite
-
From (Per Person)
A$14,164
Save 2,316
Per Person
View Trip
46 Day World Cruise: South Pacific & Panama Canal with Seabourn
Cruise
 (1)

46 Days (45 Nights) Brisbane to Miami
Operator: Seabourn
Ship: Seabourn Quest
Departure: 15 April 2027
Visits: Australia, New Caledonia, Vanuatu, Fiji +7 more, Samoa, USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Exclusive Savings
Oceanview
$26,521
Balcony
$30,539
Suite
$66,701
From (Per Person)
A$26,521
Save 477
Per Person
View Trip
13 Day Costa Rica, Panama from the Atlantic to the Pacific via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Operator: Emerald Cruises
Ship: Emerald Azzurra
Departure: 31 January 2029
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$14,645
Balcony
-
Suite
$17,521
From (Per Person)
A$14,645
Save 4,220
Per Person
View Trip
13 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (1)

13 Days (12 Nights) Fort-de-France to Colon
Operator: Ponant
Ship: Le Bellot
Departure: 26 October 2026
Visits: Martinique, Guadeloupe, Saint Lucia, Saint Vincent, Holland, Colombia, Panama
Exclusive Savings
Balcony
$11,244
Suite
$15,842
From (Per Person)
A$11,244
Save 296
Per Person
View Trip
17 Day Panama Canal: Miami to Los Angeles with Virgin Voyages
Cruise
 (1)

17 Days (16 Nights) Miami to Los Angeles
Operator: Virgin Voyages
Ship: Brilliant Lady
Departures: Mar 2027 to Feb 2028
Visits: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Drinks On Us
Inside
$3,047
Oceanview
$3,047
Balcony
$3,755
Suite
$12,966
From (Per Person)
A$3,047
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 11 November 2027
Visits: USA, Bonaire, Aruba, Dominican Republic +7 more, Jamaica, Cayman Islands, Colombia, Panama, Costa Rica, Honduras, Belize
Exclusive Savings
Inside
$3,607
Oceanview
-
Balcony
$4,756
Suite
-
From (Per Person)
A$3,607
Per Person
View Trip
15 Day Panama Canal To Machu Picchu with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Lima
Operator: Oceania
Ship: Oceania Sirena
Departure: 05 January 2028
Visits: USA, Cayman Islands, Jamaica, Colombia, Panama, Ecuador, Peru
Your World Inclusions
Exclusive Savings
Inside
$7,834
Oceanview
$8,183
Balcony
$9,939
Suite
$14,061
From (Per Person)
A$7,834
Save 2,166
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Island Princess
Departure: 28 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$3,195
Oceanview
$3,334
Balcony
$3,433
Suite
$5,690
From (Per Person)
A$3,195
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Emerald Princess
Departure: 24 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$1,948
Oceanview
$2,324
Balcony
$4,304
Suite
$5,274
From (Per Person)
A$1,948
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise

17 Days (16 Nights) Los Angeles to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Just Cruise Fare
Exclusive Savings
Inside
$2,570
Oceanview
-
Balcony
-
Suite
-
From (Per Person)
A$2,570
Per Person
View Trip
14 Day Cycle Nicaragua to the Panama Canal with Explore Worldwide
Tour

14 Days Granada to Panama City
Operator: Explore
Departures: Jan 2027 to Nov 2027
Trip Styles: Adventure, Cycling
Visits: Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$7,392
Save 548
Per Person
View Trip
30 Day Hamburg To Los Angeles with Cunard
Cruise

30 Days (29 Nights) Hamburg to Los Angeles
Operator: Cunard
Ship: Queen Anne
Departure: 09 January 2028
Visits: Germany, England, Portugal, USA +4 more, Colombia, Panama, Guatemala, Mexico
Exclusive Savings
Inside
$8,206
Oceanview
$10,879
Balcony
$12,661
Suite
$39,114
From (Per Person)
A$8,206
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,277
Suite
$11,864
From (Per Person)
A$11,277
Save 7,413
Per Person
View Trip
21 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

21 Days (20 Nights) Los Angeles to New York
Operator: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica +4 more, Panama, Colombia, Jamaica, Bahamas
Just Cruise Fare
Exclusive Savings
Inside
$4,487
Oceanview
$5,826
Balcony
$6,794
Suite
$7,166
From (Per Person)
A$4,487
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Operator: Scenic
Ships: Scenic Eclipse I
Departures: Oct 2027 to Oct 2028
Visits: Panama, Colombia, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$13,769
Suite
$18,649
From (Per Person)
A$13,769
Save 6,226
Per Person
View Trip
18 Day Splendours of Central America with Cox & Kings
New ReleaseTour

18 Days Panama City to Guatemala City
Operator: Cox & Kings
Departures: Nov 2026 to Nov 2027
Trip Styles: Coach, Small Group, Scenic
Visits: Panama, Costa Rica, Nicaragua, El Salvador, Belize, Guatemala
Exclusive Savings
From (Per Person)
A$7,835
Save 200
Per Person
View Trip
152 Day Roundtrip Fort Lauderdale with Crystal Cruises
New ReleaseCruise

152 Days (151 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Crystal
Ship: Crystal Symphony
Departure: 11 January 2028
Visits: USA, Mexico, Belize, Guatemala +36 more, Honduras, Costa Rica, Colombia, Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, American Samoa, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Indonesia, Philippines, Vietnam, Singapore, Malaysia, Thailand, India, Sri Lanka, Oman, United Arab Emirates, Saudi Arabia, Jordan, Egypt, Greece, Sicily, Malta, Tunisia, Italy, Spain, Portugal, Bermuda
Exclusive Savings
Oceanview
$119,360
Balcony
$146,757
Suite
$150,267
From (Per Person)
A$119,360
Save 2,640
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Dec 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,645
Save 954
Per Person
View Trip
11 Day Wonders of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Cartagena to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,063
Suite
$10,155
From (Per Person)
A$8,063
Save 1,785
Per Person
View Trip
11 Day Fort Lauderdale to Cartagena with Crystal Cruises
New ReleaseCruise

11 Days (10 Nights) Fort Lauderdale to Cartagena
Operator: Crystal
Ship: Crystal Symphony
Departure: 22 November 2027
Visits: USA, Mexico, Belize, Guatemala +4 more, Honduras, Costa Rica, Panama, Colombia
Exclusive Savings
Oceanview
$6,177
Balcony
$8,634
Suite
$8,546
From (Per Person)
A$6,177
Save 2,223
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,715
Save 105
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Princess
Ship: Caribbean Princess
Departures: Oct 2026 to Jan 2027
Visits: USA, Curacao, Colombia, Panama, Costa Rica, Bahamas
Exclusive Savings
Inside
$1,518
Oceanview
$1,740
Balcony
$3,333
Suite
$5,274
From (Per Person)
A$1,518
Per Person
View Trip
13 Day Azure ABCs & Panama Passage with Oceania Cruises
Cruise

13 Days (12 Nights) Miami to Panama City
Operator: Oceania
Ship: Oceania Sonata
Departure: 30 January 2029
Visits: USA, Dominican Republic, Bonaire, Curacao +4 more, Aruba, Colombia, Costa Rica, Panama
Your World Inclusions
Exclusive Savings
Balcony
$9,301
Suite
$12,473
From (Per Person)
A$9,301
Save 2,259
Per Person
View Trip
15 Day Carnival Of Caribbean Colors with Regent Seven Seas
Cruise

15 Days (14 Nights) Panama City to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 31 March 2027
Visits: Panama, Colombia, Aruba, Curacao +6 more, Bonaire, Grenada, Saint Lucia, Saint Barthelemy, Virgin Islands, USA
Exclusive Savings
Balcony
$12,853
Suite
$13,570
From (Per Person)
A$12,853
Save 8,237
Per Person
View Trip
Results: 181-210 of 373

No trips found. Try adjusting the search filters.




Trips found! Scroll up to view.

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

Departure Months

October November December January February March April May June July August September

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations