Home > Tours > Latin America Tours > Central America Tours > Panama Tours & Cruises > April

Panama Tours & Cruises Starting In April 2027, 2028 and 2029

Are you planning a tour to Panama in April 2027, 2028 or 2029? Choose from 62 unique cruises, small group tours and adventures with 733 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
Filter Results
62 Trips (733 Departures)
62 Trips (733 Departures)
Departures
Duration
6 Days
62 Days
Types
Budget
Start & End Cities
Operators
Show More...
Price
$900pp
$245,249pp
Countries
Show More...
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Aug 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 161
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Aug 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 105
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Oct 2026 to Feb 2028
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,322
Save 177
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$10,440
Suite
$17,366
From (Per Person)
A$10,440
Save 460
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Aug 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,003
Save 917
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$3,086
Save 72
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,812
Save 40
Per Person
View Trip
12 Day Costa Rica & the Panama Canal with Aurora Expeditions
New ReleaseCruise

12 Days (11 Nights) San Jose to Panama City
Operator: Aurora Expeditions
Ship: Sylvia Earle
Departure: 09 April 2027
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
-
Balcony
$24,448
Suite
$35,833
From (Per Person)
A$24,448
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 802
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,466
Oceanview
$1,623
Balcony
$2,197
Suite
$2,578
From (Per Person)
A$1,466
Save 1,173
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,391
Oceanview
$1,547
Balcony
$2,081
Suite
$2,474
From (Per Person)
A$1,391
Save 1,269
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,389
Oceanview
$1,545
Balcony
$2,079
Suite
$2,371
From (Per Person)
A$1,389
Save 926
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,464
Oceanview
$1,621
Balcony
$2,164
Suite
$2,529
From (Per Person)
A$1,464
Save 2,832
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,208
Oceanview
$1,357
Balcony
$1,739
Suite
$1,890
From (Per Person)
A$1,208
Save 2,840
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visits: USA, Colombia, Panama, Mexico
Exclusive Savings
Inside
$2,575
Oceanview
$2,961
Balcony
$3,832
Suite
$15,523
From (Per Person)
A$2,575
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,460
Oceanview
$1,621
Balcony
$2,289
Suite
$2,578
From (Per Person)
A$1,460
Save 971
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) Cartagena to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Nov 2026 to Apr 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,388
Oceanview
$1,644
Balcony
$2,258
Suite
$2,672
From (Per Person)
A$1,388
Save 1,198
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Star Princess
Departure: 03 April 2027
Visits: USA, Aruba, Panama, Mexico
Sanctuary Collection
Exclusive Savings
Inside
$2,288
Oceanview
$3,357
Balcony
$4,288
Suite
$7,961
From (Per Person)
A$2,288
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 11 April 2027
Visits: Colombia, Aruba, Bonaire, Curacao, Panama
Exclusive Savings
Inside
$2,419
Oceanview
$2,628
Balcony
$3,003
Suite
$3,391
From (Per Person)
A$2,419
Save 1,304
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2028
Visits: USA, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$3,050
Oceanview
$3,337
Balcony
$4,248
Suite
$13,533
From (Per Person)
A$3,050
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Colombia, Bonaire, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,657
Oceanview
$1,861
Balcony
$2,537
Suite
$2,816
From (Per Person)
A$1,657
Save 1,935
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,091
Oceanview
$2,161
Balcony
$3,131
Suite
$5,016
From (Per Person)
A$2,091
Per Person
View Trip
16 Day World Cruise Segment - Panama Canal with Princess
Cruise
 (4)

16 Days (15 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Coral Princess
Departures: Jan 2028 to Apr 2028
Visits: USA, Colombia, Panama, El Salvador, Mexico
Exclusive Savings
Inside
$2,680
Oceanview
$2,919
Balcony
$3,394
Suite
$6,294
From (Per Person)
A$2,680
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ships: Emerald Princess, Island Princess, Sapphire Princess
Departures: Nov 2026 to Apr 2028
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,121
Oceanview
$2,326
Balcony
$3,310
Suite
$5,487
From (Per Person)
A$2,121
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 10 April 2027
Visits: Panama, Colombia, Aruba, Bonaire, Curacao
Exclusive Savings
Inside
$2,263
Oceanview
$2,677
Balcony
$3,223
Suite
$3,422
From (Per Person)
A$2,263
Save 1,220
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise
 (13)

15 Days (14 Nights) Los Angeles to Miami
Operator: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$3,677
Oceanview
$4,350
Balcony
$5,578
Suite
$11,785
From (Per Person)
A$3,677
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Panama, Colombia, Bonaire, Aruba, Curacao
Exclusive Savings
Inside
$1,581
Oceanview
$1,772
Balcony
$2,388
Suite
$2,872
From (Per Person)
A$1,581
Save 1,185
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (12)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Crown Princess
Departure: 04 April 2027
Visits: USA, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$1,864
Oceanview
$2,299
Balcony
$3,250
Suite
$5,140
From (Per Person)
A$1,864
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

26 Days (25 Nights) Miami to Seattle
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visits: USA, Colombia, Panama, Mexico, Canada
Exclusive Savings
Inside
-
Oceanview
$5,129
Balcony
$6,327
Suite
-
From (Per Person)
A$5,129
Per Person
View Trip
12 Day A Journey Of Mayan Discovery & Mexican Exploration with Explora Journeys
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Operator: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visits: Panama, El Salvador, Guatemala, Mexico, USA
Exclusive Savings
Suite
$10,692
From (Per Person)
A$10,692
Save 218
Per Person
View Trip
Results: 1-30 of 62

No trips found. Try adjusting the search filters.




Trips found! Scroll up to view.

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

Travel Styles

18-30's Tours Active Adventures Festivals & Events Small Group Tours

Trip Lengths

1 Month 10 Day 2 Week 3 Week 4 Week

Departure Months

August September October November December January February March April May June July

Countries

Chile Colombia Costa Rica Ecuador Peru

Cities

Tours from Cartagena Tours from San Jose Tours from Santiago Tours from Santiago

Routes

Tours from Los Angeles to San Francisco Tours from Los Angeles to Los Angeles Tours from New York to Los Angeles Tours from New York to New York

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations