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Panama Tours & Cruises Starting In April 2027, 2028 and 2029

Are you planning a tour to Panama in April 2027, 2028 or 2029? Choose from 63 unique cruises, small group tours and adventures with 757 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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63 Trips (757 Departures)
63 Trips (757 Departures)
Departures
Duration
6 Days
62 Days
Types
Budget
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Price
$900pp
$203,830pp
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6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Aug 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,322
Save 177
Per Person
View Trip
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Aug 2026 to Dec 2027
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 146
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Aug 2026 to Dec 2027
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 96
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$10,440
Suite
$17,366
From (Per Person)
A$10,440
Save 435
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Nov 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,980
Save 399
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Nov 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,701
Save 228
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Jul 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,003
Save 917
Per Person
View Trip
12 Day Costa Rica & the Panama Canal with Aurora Expeditions
New ReleaseCruise

12 Days (11 Nights) San Jose to Panama City
Cruise Line: Aurora Expeditions
Ship: Sylvia Earle
Departure: 09 April 2027
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
-
Balcony
$24,448
Suite
$35,833
From (Per Person)
A$24,448
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 136
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,460
Oceanview
$1,616
Balcony
$1,930
Suite
$2,254
From (Per Person)
A$1,460
Save 1,525
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) Cartagena to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Nov 2026 to Apr 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,384
Oceanview
$1,639
Balcony
$2,258
Suite
$2,498
From (Per Person)
A$1,384
Save 960
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,083
Oceanview
$1,293
Balcony
$1,580
Suite
$2,268
From (Per Person)
A$1,083
Save 1,676
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,462
Oceanview
$1,618
Balcony
$2,197
Suite
$2,459
From (Per Person)
A$1,462
Save 970
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,386
Oceanview
$1,543
Balcony
$2,032
Suite
$2,300
From (Per Person)
A$1,386
Save 1,275
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,460
Oceanview
$1,616
Balcony
$2,289
Suite
$2,455
From (Per Person)
A$1,460
Save 969
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visits: USA, Colombia, Panama, Mexico
Exclusive Savings
Inside
$2,308
Oceanview
$2,961
Balcony
$3,832
Suite
$13,236
From (Per Person)
A$2,308
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,384
Oceanview
$1,541
Balcony
$2,079
Suite
$2,298
From (Per Person)
A$1,384
Save 924
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 03 April 2027
Visits: USA, Aruba, Panama, Mexico
Sanctuary Collection
Exclusive Savings
Inside
$2,288
Oceanview
$3,357
Balcony
$4,288
Suite
$7,961
From (Per Person)
A$2,288
Per Person
View Trip
16 Day World Cruise Segment - Panama Canal with Princess
Cruise
 (4)

16 Days (15 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Coral Princess
Departures: Jan 2028 to Apr 2028
Visits: USA, Colombia, Panama, El Salvador, Mexico
Exclusive Savings
Inside
$2,680
Oceanview
$2,919
Balcony
$3,394
Suite
$6,294
From (Per Person)
A$2,680
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,091
Oceanview
$2,161
Balcony
$2,895
Suite
$4,438
From (Per Person)
A$2,091
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise
 (13)

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$3,677
Oceanview
$4,350
Balcony
$5,578
Suite
-
From (Per Person)
A$3,677
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 11 April 2027
Visits: Colombia, Aruba, Bonaire, Curacao, Panama
Exclusive Savings
Inside
$2,046
Oceanview
$2,219
Balcony
$3,017
Suite
$3,330
From (Per Person)
A$2,046
Save 1,130
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (12)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Crown Princess
Departure: 04 April 2027
Visits: USA, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$1,953
Oceanview
$2,479
Balcony
$3,378
Suite
$5,101
From (Per Person)
A$1,953
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

26 Days (25 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visits: USA, Colombia, Panama, Mexico, Canada
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,723
Suite
-
From (Per Person)
A$6,723
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ships: Emerald Princess, Island Princess, Sapphire Princess
Departures: Nov 2026 to Apr 2028
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,051
Oceanview
$2,312
Balcony
$3,158
Suite
$4,714
From (Per Person)
A$2,051
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 10 April 2027
Visits: Panama, Colombia, Aruba, Bonaire, Curacao
Exclusive Savings
Inside
$1,893
Oceanview
$2,264
Balcony
$3,125
Suite
$3,332
From (Per Person)
A$1,893
Save 1,048
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2028
Visits: USA, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$3,050
Oceanview
$3,337
Balcony
$4,248
Suite
$13,533
From (Per Person)
A$3,050
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Colombia, Bonaire, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,653
Oceanview
$1,857
Balcony
$2,537
Suite
$2,791
From (Per Person)
A$1,653
Save 1,149
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Panama, Colombia, Bonaire, Aruba, Curacao
Exclusive Savings
Inside
$1,302
Oceanview
$1,303
Balcony
$2,388
Suite
$2,641
From (Per Person)
A$1,302
Save 1,180
Per Person
View Trip
12 Day A Journey Of Mayan Discovery & Mexican Exploration with Explora Journeys
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visits: Panama, El Salvador, Guatemala, Mexico, USA
Exclusive Savings
Suite
$10,858
From (Per Person)
A$10,858
Save 222
Per Person
View Trip
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