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3 Week Trips to Panama

Looking to explore Panama for 3 weeks? Then choose from our range of cruises, small group tours and adventures with 5 of the best tour operators to Panama. October is the most popular month to travel to Panama and we have 11 departures available.
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10 trips (11 trip Departures)
21 Day Seattle to Miami with Silversea
Cruise
 (1)

21 Days (20 Nights) Seattle to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 11 May 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,880
Suite
$17,370
From
US$10,880
Save 2,720
Per Person
View Trip
21 Day Panama Canal & Pacific Coast with Princess
Cruise
 (6)

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 09 October 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,837
Oceanview
$2,112
Balcony
$2,706
Suite
$4,789
From
US$1,837
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,109
Oceanview
$2,209
Balcony
$3,479
Suite
$5,845
From
US$2,109
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,384
Oceanview
$2,584
Balcony
$3,890
Suite
$6,605
From
US$2,384
Per Person
View Trip
21 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

21 Days (20 Nights) Los Angeles to New York
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Bahamas
Exclusive Savings
Inside
$2,368
Oceanview
$3,144
Balcony
$3,872
Suite
$4,454
From
US$2,368
Save 51
Per Person
View Trip
21 Day Panama Canal Connoisseur with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Tampa to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 25 March 2026
Visit: USA, Mexico, Belize, Honduras (+7 more), Costa Rica, Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$6,530
Oceanview
$6,918
Balcony
-
Suite
-
From
US$6,530
Save 6,768
Per Person
View Trip
21 Day Coastal Calm & Coconuts with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 January 2028
Visit: USA, Mexico, Belize, Honduras (+7 more), Costa Rica, Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$6,091
Oceanview
$7,643
Balcony
$9,147
Suite
$12,833
From
US$6,091
Save 6,307
Per Person
View Trip
21 Day Treasures Of The Tropics with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 March 2028
Visit: USA, Cayman Islands, Jamaica, Aruba (+7 more), Curacao, Colombia, Panama, Costa Rica, Honduras, Guatemala, Mexico
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,605
Oceanview
$7,448
Balcony
$8,952
Suite
$12,832
From
US$5,605
Save 5,793
Per Person
View Trip
21 Day Panama Canal Navigator with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 March 2027
Visit: USA, Mexico, Belize, Guatemala (+8 more), Honduras, Costa Rica, Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$6,094
Oceanview
$7,549
Balcony
$8,713
Suite
$12,060
From
US$6,094
Save 6,304
Per Person
View Trip
21 Day Panama Canal & Caribbean with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 January 2027
Visit: USA, Mexico, Belize, Guatemala (+8 more), Honduras, Costa Rica, Panama, Colombia, Aruba, Curacao, Jamaica, Cayman Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,093
Oceanview
-
Balcony
$9,197
Suite
$12,786
From
US$6,093
Save 6,305
Per Person
View Trip
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Central America Tours

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