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Panama Tours & Cruises Starting In September 2027, 2028 and 2029

Are you planning a tour to Panama in September 2027, 2028 or 2029? Choose from 21 unique cruises, small group tours and adventures with 378 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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21 Trips (378 Departures)
21 Trips (378 Departures)
Departures
Duration
6 Days
81 Days
Types
Budget
Start & End Cities
Operators
Show More...
Price
$900pp
$198,630pp
Countries
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9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 161
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 105
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visits: USA, Mexico, Panama, Colombia
Exclusive Savings
Inside
$3,401
Oceanview
$3,688
Balcony
$4,629
Suite
$13,851
From (Per Person)
A$3,401
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,350
Oceanview
$2,377
Balcony
$3,569
Suite
$4,859
From (Per Person)
A$2,350
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$14,029
From (Per Person)
A$14,029
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Operator: Princess
Ship: Star Princess
Departure: 27 September 2026
Visits: Canada, USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$3,620
Oceanview
$4,653
Balcony
$5,590
Suite
$10,752
From (Per Person)
A$3,620
Per Person
View Trip
22 Day Seattle To Miami with Cunard
Cruise
 (13)

22 Days (21 Nights) Seattle to Miami
Operator: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2026
Visits: USA, Mexico, Guatemala, Panama, Curacao, Aruba
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,513
Suite
$17,245
From (Per Person)
A$10,513
Per Person
View Trip
23 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

23 Days (22 Nights) Vancouver to Fort Lauderdale
Operator: Princess
Ship: Coral Princess
Departure: 23 September 2026
Visits: Canada, USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$4,022
Oceanview
$4,226
Balcony
$5,854
Suite
$6,200
From (Per Person)
A$4,022
Per Person
View Trip
19 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

19 Days (18 Nights) Los Angeles to New York
Operator: Princess
Ship: Coral Princess
Departure: 27 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,622
Oceanview
$2,919
Balcony
$4,111
Suite
$6,404
From (Per Person)
A$2,622
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$6,149
Save 1,317
Per Person
View Trip
29 Day Seattle To Miami with Cunard
Cruise
 (13)

29 Days (28 Nights) Seattle to Miami
Operator: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2026
Visits: USA, Canada, Mexico, Guatemala, Panama, Curacao, Aruba
Exclusive Savings
Inside
-
Oceanview
$9,424
Balcony
-
Suite
-
From (Per Person)
A$9,424
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Operator: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visits: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$4,426
Oceanview
$4,695
Balcony
$5,357
Suite
$9,535
From (Per Person)
A$4,426
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

25 Days (24 Nights) Seattle to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia, Cayman Islands, Jamaica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,600
Suite
-
From (Per Person)
A$3,600
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Operator: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$3,565
Oceanview
$3,493
Balcony
$5,010
Suite
-
From (Per Person)
A$5,464
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operator: Intrepid
Departures: Oct 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$10,540
Save 1,325
Per Person
View Trip
18 Day Panama Canal Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 30 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica +4 more, Panama, Colombia, Jamaica, Cayman Islands
Just Cruise Fare
Exclusive Savings
Inside
$4,206
Oceanview
$5,054
Balcony
$5,769
Suite
$6,096
From (Per Person)
A$4,206
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Sep 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$13,195
Save 1,765
Per Person
View Trip
25 Day Atlantic Crossing: Halifax To South America with Seabourn
Cruise

25 Days (24 Nights) Halifax to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 24 September 2028
Visits: Canada, Bermuda, Puerto Rico, Aruba +4 more, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$18,305
Suite
$26,380
From (Per Person)
A$18,305
Save 324
Per Person
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Operator: Viking
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visits: USA, Canada, Bahamas, Jamaica +5 more, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$96,035
Suite
$128,375
From (Per Person)
A$96,035
Save 2,020
Per Person
View Trip
43 Day Exploring Greenland, Labrador Coast & Panama Canal with Seabourn
Cruise

43 Days (42 Nights) Reykjavik to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 06 September 2028
Visits: Iceland, Greenland, Canada, Bermuda +6 more, Puerto Rico, Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$46,340
Suite
$65,352
From (Per Person)
A$46,340
Save 858
Per Person
View Trip
81 Day Arctic to Antarctic Explorer with Viking Cruises
Cruise

81 Days (80 Nights) Nuuk to Buenos Aires
Operator: Viking
Ship: Viking Octantis
Departure: 03 September 2029
Visits: Greenland, Canada, USA, Bahamas +6 more, Jamaica, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$130,335
Suite
$179,335
From (Per Person)
A$130,335
Save 2,660
Per Person
View Trip
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