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Panama Tours & Cruises Starting In September 2026, 2027, 2028 and 2029

Are you planning a tour to Panama in September 2026, 2027, 2028 or 2029? Choose from 22 unique cruises, small group tours and adventures with 198 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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22 Trips (198 Departures)
22 Trips (198 Departures)
Departures
Duration
6 Days
81 Days
Types
Budget
Start & End Cities
Operators
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Price
$900pp
$150,450pp
Countries
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6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Sep 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,715
Save 105
Per Person
View Trip
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Sep 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,092
Save 161
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,464
Oceanview
$1,621
Balcony
$2,164
Suite
$2,529
From (Per Person)
A$1,464
Save 2,832
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,389
Oceanview
$1,545
Balcony
$1,996
Suite
$2,296
From (Per Person)
A$1,389
Save 1,909
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visits: USA, Mexico, Panama, Colombia
Exclusive Savings
Inside
$3,401
Oceanview
$3,688
Balcony
$4,629
Suite
$13,851
From (Per Person)
A$3,401
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Panama, Colombia, Bonaire, Aruba, Curacao
Exclusive Savings
Inside
$1,581
Oceanview
$1,772
Balcony
$2,388
Suite
$2,872
From (Per Person)
A$1,581
Save 2,028
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,161
Oceanview
$2,271
Balcony
$3,269
Suite
$4,864
From (Per Person)
A$2,161
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
-
Oceanview
$2,312
Balcony
$3,361
Suite
$14,029
From (Per Person)
A$2,312
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Operator: Princess
Ship: Star Princess
Departure: 27 September 2026
Visits: Canada, USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$3,627
Oceanview
$4,472
Balcony
$4,927
Suite
$8,722
From (Per Person)
A$3,627
Per Person
View Trip
10 Day Guayaquil to San Juan with Crystal Cruises
New ReleaseCruise

10 Days (9 Nights) Guayaquil to San Juan
Operator: Crystal
Ship: Crystal Symphony
Departure: 05 September 2026
Visits: Ecuador, Panama, Colombia, Dominican Republic, Puerto Rico
Exclusive Savings
Oceanview
$6,275
Balcony
$7,445
Suite
$7,932
From (Per Person)
A$6,275
Save 1,125
Per Person
View Trip
19 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

19 Days (18 Nights) Los Angeles to New York
Operator: Princess
Ship: Coral Princess
Departure: 27 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,687
Oceanview
$2,855
Balcony
$4,380
Suite
$6,577
From (Per Person)
A$2,687
Per Person
View Trip
23 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

23 Days (22 Nights) Vancouver to Fort Lauderdale
Operator: Princess
Ship: Coral Princess
Departure: 23 September 2026
Visits: Canada, USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
-
Oceanview
$4,232
Balcony
$5,424
Suite
-
From (Per Person)
A$4,232
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

25 Days (24 Nights) Seattle to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia, Cayman Islands, Jamaica
Exclusive Savings
Inside
-
Oceanview
$3,244
Balcony
-
Suite
-
From (Per Person)
A$3,244
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Operator: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visits: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$4,433
Oceanview
$4,702
Balcony
$5,364
Suite
$9,541
From (Per Person)
A$4,433
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Operator: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$3,759
Oceanview
$3,681
Balcony
$5,329
Suite
-
From (Per Person)
A$3,681
Save 2,131
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Vancouver to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 27 September 2026
Visits: Canada, USA, Mexico, Guatemala +4 more, El Salvador, Panama, Colombia, Bahamas
Have It All Fare Option
Exclusive Savings
Inside
$3,378
Oceanview
$3,526
Balcony
$5,308
Suite
$14,337
From (Per Person)
A$3,378
Per Person
View Trip
18 Day Panama Canal Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 30 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica +4 more, Panama, Colombia, Jamaica, Cayman Islands
Just Cruise Fare
Exclusive Savings
Inside
$4,206
Oceanview
$5,054
Balcony
$5,769
Suite
$6,096
From (Per Person)
A$4,206
Per Person
View Trip
25 Day Atlantic Crossing: Halifax To South America with Seabourn
Cruise

25 Days (24 Nights) Halifax to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 24 September 2028
Visits: Canada, Bermuda, Puerto Rico, Aruba +4 more, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$16,718
Suite
$24,492
From (Per Person)
A$16,718
Save 291
Per Person
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Operator: Viking
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visits: USA, Canada, Bahamas, Jamaica +5 more, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$96,035
Suite
$128,375
From (Per Person)
A$96,035
Save 2,020
Per Person
View Trip
43 Day Exploring Greenland, Labrador Coast & Panama Canal with Seabourn
Cruise

43 Days (42 Nights) Reykjavik to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 06 September 2028
Visits: Iceland, Greenland, Canada, Bermuda +6 more, Puerto Rico, Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$43,890
Suite
$63,392
From (Per Person)
A$43,890
Save 808
Per Person
View Trip
81 Day Arctic to Antarctic Explorer with Viking Cruises
Cruise

81 Days (80 Nights) Nuuk to Buenos Aires
Operator: Viking
Ship: Viking Octantis
Departure: 03 September 2029
Visits: Greenland, Canada, USA, Bahamas +6 more, Jamaica, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$130,335
Suite
$179,335
From (Per Person)
A$130,335
Save 2,660
Per Person
View Trip
67 Day Grand Voyage: Caribbean to the Panama Canal & Antarctica with Scenic
New ReleaseCruise

67 Days (66 Nights) New York to Buenos Aires
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 24 September 2028
Visits: USA, Bahamas, Turks and Caicos Islands, Colombia +6 more, Panama, Ecuador, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$94,701
Suite
$133,093
From (Per Person)
A$94,701
Save 25,049
Per Person
View Trip
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