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Panama Tours & Cruises Starting In September 2026, 2027, 2028 and 2029

Are you planning a tour to Panama in September 2026, 2027, 2028 or 2029? Choose from 26 unique cruises, small group tours and adventures with 511 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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26 Trips (511 Trip Departures)
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operated By: Globus
Departures: Aug 2026 to Mar 2027
Trip Styles: Short Break, Scenic
Visit: Panama
Exclusive Savings
From
A$2,715
Save 106
Per Person
View Trip
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operated By: Globus
Departures: Aug 2026 to Mar 2027
Trip Style: Scenic
Visit: Panama
Exclusive Savings
From
A$4,092
Save 163
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama
Exclusive Savings
From
A$1,999
Save 806
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visit: USA, Mexico, Panama, Colombia
Exclusive Savings
Inside
$3,382
Oceanview
$3,669
Balcony
$4,610
Suite
$13,813
From
A$3,382
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,199
Oceanview
$1,214
Balcony
$1,579
Suite
$1,997
From
A$1,199
Save 1,773
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visit: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,384
Oceanview
$1,385
Balcony
$1,821
Suite
$2,109
From
A$1,384
Save 2,067
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Exclusive Savings
Inside
$2,141
Oceanview
$2,313
Balcony
$2,701
Suite
$3,972
From
A$2,141
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visit: Panama, Colombia, Bonaire, Aruba, Curacao
Exclusive Savings
Inside
$1,426
Oceanview
$1,566
Balcony
$2,388
Suite
$2,715
From
A$1,426
Save 892
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
$2,699
Oceanview
$3,006
Balcony
$3,808
Suite
-
From
A$2,699
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visit: Colombia, Bonaire, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,653
Oceanview
$1,857
Balcony
$2,537
Suite
$2,866
From
A$1,653
Save 942
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 27 September 2026
Visit: Canada, USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$3,593
Oceanview
$4,590
Balcony
$5,964
Suite
$8,005
From
A$3,593
Per Person
View Trip
23 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

23 Days (22 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Coral Princess
Departure: 23 September 2026
Visit: Canada, USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Exclusive Savings
Inside
$4,185
Oceanview
$4,094
Balcony
$5,424
Suite
$5,424
From
A$4,094
Per Person
View Trip
19 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

19 Days (18 Nights) Los Angeles to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 27 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Exclusive Savings
Inside
$2,924
Oceanview
$3,202
Balcony
$4,865
Suite
$6,944
From
A$2,924
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
A$4,480
Save 1,723
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Exclusive Savings
Inside
$3,928
Oceanview
$4,526
Balcony
$6,126
Suite
$9,126
From
A$3,928
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

25 Days (24 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia, Cayman Islands, Jamaica
Exclusive Savings
Inside
$4,160
Oceanview
$4,685
Balcony
-
Suite
-
From
A$4,160
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$4,452
Oceanview
$4,514
Balcony
$7,338
Suite
-
From
A$4,452
Save 2,404
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operated By: Intrepid Travel
Departures: Jul 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
A$8,201
Save 2,294
Per Person
View Trip
18 Day Panama Canal Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 30 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Cayman Islands
Just Cruise Fare
Exclusive Savings
Inside
$4,206
Oceanview
$5,054
Balcony
$5,769
Suite
$6,096
From
A$4,206
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 27 September 2026
Visit: Canada, USA, Mexico, Guatemala (+4 more), El Salvador, Panama, Colombia, Bahamas
Flash Deal
Have It All Fare Option
Exclusive Savings
Inside
$3,378
Oceanview
$3,526
Balcony
$5,308
Suite
$8,724
From
A$3,378
Per Person
View Trip
25 Day Atlantic Crossing: Halifax To South America with Seabourn
Cruise

25 Days (24 Nights) Halifax to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 24 September 2028
Visit: Canada, Bermuda, Puerto Rico, Aruba (+4 more), Panama, Ecuador, Peru, Chile
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,354
Suite
$26,606
From
A$19,354
Save 345
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operated By: Intrepid Travel
Departures: Sep 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
A$10,433
Save 3,947
Per Person
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visit: USA, Canada, Bahamas, Jamaica (+5 more), Panama, Peru, Chile, Argentina, Antarctica
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$96,035
Suite
$128,375
From
A$96,035
Save 2,020
Per Person
View Trip
81 Day Arctic to Antarctic Explorer with Viking Cruises
Cruise
 (1)

81 Days (80 Nights) Nuuk to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visit: Greenland, Canada, USA, Bahamas (+6 more), Jamaica, Panama, Peru, Chile, Argentina, Antarctica
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$124,063
Suite
$179,335
From
A$124,063
Save 2,660
Per Person
View Trip
43 Day Exploring Greenland, Labrador Coast & Panama Canal with Seabourn
Cruise

43 Days (42 Nights) Reykjavik to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 06 September 2028
Visit: Iceland, Greenland, Canada, Bermuda (+6 more), Puerto Rico, Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$45,851
Suite
$66,431
From
A$45,851
Save 848
Per Person
View Trip
67 Day Grand Voyage: Caribbean to the Panama Canal & Antarctica with Scenic
New ReleaseCruise

67 Days (66 Nights) New York to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 24 September 2028
Visit: USA, Bahamas, Turks and Caicos Islands, Colombia (+6 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$101,091
Suite
$133,093
From
A$101,091
Save 25,179
Per Person
View Trip
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