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Panama Tours & Cruises Starting In September 2027, 2028 and 2029

Are you planning a tour to Panama in September 2027, 2028 or 2029? Choose from 19 unique cruises, small group tours and adventures with 593 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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19 Trips (593 Departures)
19 Trips (593 Departures)
Departures
Duration
6 Days
81 Days
Types
Budget
Start & End Cities
Operators
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Price
$1,000pp
$147,495pp
Countries
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9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Nov 2026 to Mar 2028
Interests: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 161
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Nov 2026 to Mar 2028
Interests: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 105
Per Person
View Trip
11 Day Wonders of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Cartagena to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,184
Suite
$10,276
From (Per Person)
A$8,184
Save 1,781
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Interests: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,812
Save 354
Per Person
View Trip
14 Day Magic of Colombia (MedellÍn & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

14 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$9,120
Suite
$12,690
From (Per Person)
A$9,120
Save 1,879
Per Person
View Trip
11 Day Magic of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Barranquilla to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,044
Suite
$10,276
From (Per Person)
A$8,044
Save 1,785
Per Person
View Trip
16 Day Wonders of Colombia (MedellÍn, Cartagena & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

16 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$11,829
Suite
$13,921
From (Per Person)
A$11,829
Save 1,925
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visits: USA, Mexico, Panama, Colombia
Exclusive Savings
Inside
$3,401
Oceanview
$3,688
Balcony
$4,629
Suite
$13,851
From (Per Person)
A$3,401
Per Person
View Trip
19 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

19 Days (18 Nights) Los Angeles to New York
Operator: Princess
Ship: Coral Princess
Departure: 27 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,835
Oceanview
$2,924
Balcony
$3,756
Suite
$5,696
From (Per Person)
A$2,835
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Interests: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$6,149
Save 303
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Operator: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visits: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$4,106
Oceanview
$4,841
Balcony
$5,409
Suite
$8,957
From (Per Person)
A$4,106
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Operator: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$2,199
Oceanview
$2,836
Balcony
$4,047
Suite
-
From (Per Person)
A$2,199
Save 926
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operator: Intrepid
Departures: Oct 2026 to Nov 2028
Interests: Adventure, Coach, Small Group, Scenic
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$10,540
Save 407
Per Person
View Trip
18 Day Panama Canal Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 30 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica +4 more, Panama, Colombia, Jamaica, Cayman Islands
Just Cruise Fare
Exclusive Savings
Inside
$4,086
Oceanview
$4,831
Balcony
$5,799
Suite
$6,096
From (Per Person)
A$4,086
Per Person
View Trip
25 Day Atlantic Crossing: Halifax To South America with Seabourn
Cruise

25 Days (24 Nights) Halifax to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 24 September 2028
Visits: Canada, Bermuda, Puerto Rico, Aruba +4 more, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$20,333
Suite
$27,389
From (Per Person)
A$20,333
Save 365
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Nov 2026 to Nov 2028
Interests: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$14,808
Save 494
Per Person
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Operator: Viking
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visits: USA, Canada, Bahamas, Jamaica +5 more, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$96,035
Suite
$128,375
From (Per Person)
A$96,035
Save 2,048
Per Person
View Trip
43 Day Exploring Greenland, Labrador Coast & Panama Canal with Seabourn
Cruise

43 Days (42 Nights) Reykjavik to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 06 September 2028
Visits: Iceland, Greenland, Canada, Bermuda +6 more, Puerto Rico, Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$46,340
Suite
$65,352
From (Per Person)
A$46,340
Save 858
Per Person
View Trip
81 Day Arctic to Antarctic Explorer with Viking Cruises
Cruise

81 Days (80 Nights) Nuuk to Buenos Aires
Operator: Viking
Ship: Viking Octantis
Departure: 03 September 2029
Visits: Greenland, Canada, USA, Bahamas +6 more, Jamaica, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$130,335
Suite
$179,335
From (Per Person)
A$130,335
Save 2,660
Per Person
View Trip
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