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Panama Tours & Cruises Starting In September 2026, 2027, 2028 and 2029

Are you planning a tour to Panama in September 2026, 2027, 2028 or 2029? Choose from 27 unique cruises, small group tours and adventures with 509 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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27 Trips (509 Departures)
27 Trips (509 Departures)
Departures
Duration
6 Days
81 Days
Types
Budget
Start & End Cities
Operators
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Price
$900pp
$205,420pp
Countries
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9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Aug 2026 to Mar 2027
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,092
Save 146
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Aug 2026 to Mar 2027
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,715
Save 96
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Jul 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,146
Save 774
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visits: USA, Mexico, Panama, Colombia
Exclusive Savings
Inside
$3,401
Oceanview
$3,688
Balcony
$4,629
Suite
$13,851
From (Per Person)
A$3,401
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,421
Oceanview
$1,457
Balcony
$1,821
Suite
$1,779
From (Per Person)
A$1,421
Save 1,718
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,095
Oceanview
$1,158
Balcony
$1,627
Suite
$1,894
From (Per Person)
A$1,095
Save 1,668
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Colombia, Bonaire, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,653
Oceanview
$1,857
Balcony
$2,537
Suite
$2,791
From (Per Person)
A$1,653
Save 993
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
$2,371
Oceanview
$2,460
Balcony
$3,569
Suite
$13,459
From (Per Person)
A$2,367
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,141
Oceanview
$2,313
Balcony
$2,701
Suite
$3,972
From (Per Person)
A$2,141
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Panama, Colombia, Bonaire, Aruba, Curacao
Exclusive Savings
Inside
$1,426
Oceanview
$1,441
Balcony
$2,388
Suite
$2,641
From (Per Person)
A$1,426
Save 892
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 27 September 2026
Visits: Canada, USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$3,462
Oceanview
$4,588
Balcony
$5,181
Suite
$8,371
From (Per Person)
A$3,462
Per Person
View Trip
10 Day Guayaquil to San Juan with Crystal Cruises
New ReleaseCruise

10 Days (9 Nights) Guayaquil to San Juan
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 05 September 2026
Visits: Ecuador, Panama, Colombia, Dominican Republic, Puerto Rico
Exclusive Savings
Oceanview
$6,500
Balcony
$8,600
Suite
$9,050
From (Per Person)
A$6,500
Save 900
Per Person
View Trip
23 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

23 Days (22 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Coral Princess
Departure: 23 September 2026
Visits: Canada, USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$4,323
Oceanview
$4,094
Balcony
$5,424
Suite
$5,424
From (Per Person)
A$4,094
Per Person
View Trip
19 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

19 Days (18 Nights) Los Angeles to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 27 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,924
Oceanview
$3,202
Balcony
$5,003
Suite
$6,944
From (Per Person)
A$2,924
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Jul 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$4,778
Save 1,317
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

25 Days (24 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia, Cayman Islands, Jamaica
Exclusive Savings
Inside
$4,174
Oceanview
$4,511
Balcony
-
Suite
-
From (Per Person)
A$4,174
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visits: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$4,037
Oceanview
$4,689
Balcony
$6,116
Suite
$9,056
From (Per Person)
A$4,037
Per Person
View Trip
19 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

19 Days (18 Nights) Los Angeles to Boston
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Turks and Caicos Islands
Exclusive Savings
Inside
$4,382
Oceanview
$4,444
Balcony
$6,755
Suite
-
From (Per Person)
A$4,382
Save 2,474
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operator: Intrepid
Departures: Jul 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$10,104
Save 376
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 27 September 2026
Visits: Canada, USA, Mexico, Guatemala +4 more, El Salvador, Panama, Colombia, Bahamas
Have It All Fare Option
Exclusive Savings
Inside
$3,378
Oceanview
$3,526
Balcony
$5,308
Suite
$8,724
From (Per Person)
A$3,378
Per Person
View Trip
18 Day Panama Canal Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 30 September 2027
Visits: USA, Mexico, Guatemala, Costa Rica +4 more, Panama, Colombia, Jamaica, Cayman Islands
Just Cruise Fare
Exclusive Savings
Inside
$4,206
Oceanview
$5,054
Balcony
$5,769
Suite
$6,096
From (Per Person)
A$4,206
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Sep 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$13,764
Save 448
Per Person
View Trip
25 Day Atlantic Crossing: Halifax To South America with Seabourn
Cruise

25 Days (24 Nights) Halifax to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 24 September 2028
Visits: Canada, Bermuda, Puerto Rico, Aruba +4 more, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$19,354
Suite
$26,606
From (Per Person)
A$19,354
Save 345
Per Person
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Cruise Line: Viking
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visits: USA, Canada, Bahamas, Jamaica +5 more, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$96,035
Suite
$128,375
From (Per Person)
A$96,035
Save 2,020
Per Person
View Trip
81 Day Arctic to Antarctic Explorer with Viking Cruises
Cruise

81 Days (80 Nights) Nuuk to Buenos Aires
Cruise Line: Viking
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2028 to Sep 2029
Visits: Greenland, Canada, USA, Bahamas +6 more, Jamaica, Panama, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$124,063
Suite
$179,335
From (Per Person)
A$124,063
Save 2,660
Per Person
View Trip
43 Day Exploring Greenland, Labrador Coast & Panama Canal with Seabourn
Cruise

43 Days (42 Nights) Reykjavik to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 06 September 2028
Visits: Iceland, Greenland, Canada, Bermuda +6 more, Puerto Rico, Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$45,851
Suite
$66,431
From (Per Person)
A$45,851
Save 848
Per Person
View Trip
67 Day Grand Voyage: Caribbean to the Panama Canal & Antarctica with Scenic
New ReleaseCruise

67 Days (66 Nights) New York to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 24 September 2028
Visits: USA, Bahamas, Turks and Caicos Islands, Colombia +6 more, Panama, Ecuador, Peru, Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$94,701
Suite
$133,093
From (Per Person)
A$94,701
Save 25,049
Per Person
View Trip
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