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Panama Tours & Cruises Starting In May 2027 and 2028

Are you planning a tour to Panama in May 2027 or 2028? Choose from 13 unique cruises, small group tours and adventures with 459 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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13 Trips (459 Departures)
13 Trips (459 Departures)
Departures
Duration
6 Days
59 Days
Types
Budget
Start & End Cities
Operators
Price
$900pp
$203,150pp
Countries
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6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Aug 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,322
Save 33
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Aug 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$3,086
Save 72
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Nov 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,812
Save 40
Per Person
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12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Jul 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,132
Save 657
Per Person
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27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 136
Per Person
View Trip
20 Day Panama Canal Passage with Seabourn
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
-
Oceanview
$12,862
Balcony
$18,448
Suite
$30,894
From (Per Person)
A$12,862
Save 236
Per Person
View Trip
28 Day World Cruise: Hawaii & Panama Canal with Seabourn
Cruise
 (1)

28 Days (27 Nights) Honolulu to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 03 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
-
Oceanview
$15,056
Balcony
$19,207
Suite
$33,701
From (Per Person)
A$15,056
Save 247
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Jul 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$4,778
Save 1,339
Per Person
View Trip
32 Day Panama Canal & Atlantic Passage with Seabourn
Cruise
 (1)

32 Days (31 Nights) Los Angeles to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Portugal
Exclusive Savings
Inside
-
Oceanview
$17,804
Balcony
$25,252
Suite
$41,520
From (Per Person)
A$17,804
Save 294
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (5)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara
Ship: Azamara Quest
Departure: 24 May 2027
Visits: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Exclusive Savings
Inside
$7,610
Oceanview
$8,198
Balcony
$9,286
Suite
$15,234
From (Per Person)
A$7,610
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operator: Intrepid
Departures: Jul 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$8,201
Save 2,259
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Sep 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$11,129
Save 3,447
Per Person
View Trip
36 Day San Diego To London Grand Voyage with Azamara Cruises
Cruise
 (5)

36 Days (35 Nights) San Diego to London
Cruise Line: Azamara
Ship: Azamara Quest
Departure: 24 May 2027
Visits: USA, Mexico, Guatemala, El Salvador +7 more, Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$15,999
Balcony
$17,038
Suite
$30,964
From (Per Person)
A$15,999
Save 240
Per Person
View Trip
Results: 13 results

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Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

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South & Central America Cruises

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