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Panama Tours & Cruises Starting In May 2027 and 2028

Are you planning a tour to Panama in May 2027 or 2028? Choose from 16 unique cruises, small group tours and adventures with 591 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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16 Trips (591 Departures)
16 Trips (591 Departures)
Departures
Duration
6 Days
62 Days
Types
Budget
Start & End Cities
Operators
Price
$900pp
$245,249pp
Countries
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6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Aug 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 105
Per Person
View Trip
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Aug 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 161
Per Person
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6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Oct 2026 to Feb 2028
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,322
Save 177
Per Person
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13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,812
Save 40
Per Person
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18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$3,086
Save 72
Per Person
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12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Aug 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,003
Save 917
Per Person
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27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 802
Per Person
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20 Day Panama Canal Passage with Seabourn
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Operator: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Exclusive Savings
Oceanview
$11,308
Balcony
$15,685
Suite
$26,264
From (Per Person)
A$11,308
Save 204
Per Person
View Trip
28 Day World Cruise: Hawaii & Panama Canal with Seabourn
Cruise
 (1)

28 Days (27 Nights) Honolulu to Miami
Operator: Seabourn
Ship: Seabourn Quest
Departure: 03 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Exclusive Savings
Oceanview
-
Balcony
$18,979
Suite
$28,655
From (Per Person)
A$18,979
Save 327
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Aug 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$4,778
Save 1,317
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (6)

18 Days (17 Nights) San Diego to Miami
Operator: Azamara
Ship: Azamara Quest
Departure: 24 May 2027
Visits: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
$7,995
Oceanview
$8,628
Balcony
$9,773
Suite
$16,048
From (Per Person)
A$7,995
Save 544
Per Person
View Trip
32 Day Panama Canal & Atlantic Passage with Seabourn
Cruise
 (1)

32 Days (31 Nights) Los Angeles to Lisbon
Operator: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Portugal
Exclusive Savings
Oceanview
$16,061
Balcony
$22,225
Suite
$35,886
From (Per Person)
A$16,061
Save 258
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operator: Intrepid
Departures: Oct 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$10,123
Save 252
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Sep 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$13,730
Save 338
Per Person
View Trip
62 Day Total Central America: Two Months of Wild with G Adventures
New ReleaseTour

62 Days Mexico City to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jun 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Guatemala, Mexico, Nicaragua, Panama +4 more, Belize, Honduras, Costa Rica, El Salvador
Exclusive Savings
From (Per Person)
A$9,113
Save 213
Per Person
View Trip
36 Day San Diego To London Grand Voyage with Azamara Cruises
Cruise
 (6)

36 Days (35 Nights) San Diego to London
Operator: Azamara
Ship: Azamara Quest
Departure: 24 May 2027
Visits: USA, Mexico, Guatemala, El Salvador +7 more, Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$16,498
Balcony
$17,578
Suite
$35,797
From (Per Person)
A$16,498
Save 1,131
Per Person
View Trip
Results: 16 results

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