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Panama Tours & Cruises Starting In May 2027 and 2028

Are you planning a tour to Panama in May 2027 or 2028? Choose from 16 unique cruises, small group tours and adventures with 609 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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16 Trips (609 Departures)
16 Trips (609 Departures)
Departures
Duration
6 Days
62 Days
Types
Budget
Start & End Cities
Operators
Price
$900pp
$203,830pp
Countries
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6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Aug 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,322
Save 177
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Aug 2026 to Dec 2027
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 96
Per Person
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9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Aug 2026 to Dec 2027
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 146
Per Person
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12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Jul 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,003
Save 917
Per Person
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18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Nov 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,980
Save 399
Per Person
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13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Nov 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,701
Save 228
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 136
Per Person
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20 Day Panama Canal Passage with Seabourn
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Exclusive Savings
Oceanview
$10,937
Balcony
$15,685
Suite
$26,264
From (Per Person)
A$10,937
Save 197
Per Person
View Trip
28 Day World Cruise: Hawaii & Panama Canal with Seabourn
Cruise
 (1)

28 Days (27 Nights) Honolulu to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 03 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Exclusive Savings
Oceanview
$14,562
Balcony
$19,208
Suite
$33,702
From (Per Person)
A$14,562
Save 237
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Aug 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$4,480
Save 1,615
Per Person
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18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (5)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara
Ship: Azamara Quest
Departure: 24 May 2027
Visits: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Exclusive Savings
Inside
$6,459
Oceanview
$6,962
Balcony
$7,874
Suite
$12,892
From (Per Person)
A$6,459
Save 430
Per Person
View Trip
32 Day Panama Canal & Atlantic Passage with Seabourn
Cruise
 (1)

32 Days (31 Nights) Los Angeles to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Portugal
Exclusive Savings
Oceanview
$18,883
Balcony
$26,135
Suite
$42,207
From (Per Person)
A$18,883
Save 316
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operator: Intrepid
Departures: Oct 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$10,123
Save 389
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Sep 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$13,730
Save 468
Per Person
View Trip
62 Day Total Central America: Two Months of Wild with G Adventures
New ReleaseTour

62 Days Mexico City to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jun 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Guatemala, Mexico, Nicaragua, Panama +4 more, Belize, Honduras, Costa Rica, El Salvador
Exclusive Savings
From (Per Person)
A$9,113
Save 213
Per Person
View Trip
36 Day San Diego To London Grand Voyage with Azamara Cruises
Cruise
 (5)

36 Days (35 Nights) San Diego to London
Cruise Line: Azamara
Ship: Azamara Quest
Departure: 24 May 2027
Visits: USA, Mexico, Guatemala, El Salvador +7 more, Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$16,498
Balcony
$17,578
Suite
$32,129
From (Per Person)
A$16,498
Save 1,131
Per Person
View Trip
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