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Panama Tours & Cruises Starting In December 2026, 2027 and 2028

Are you planning a tour to Panama in December 2026, 2027 or 2028? Choose from 81 unique cruises, small group tours and adventures with 842 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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81 Trips (842 Departures)
81 Trips (842 Departures)
Departures
Duration
6 Days
171 Days
Types
Budget
Start & End Cities
Operators
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Price
$1,000pp
$147,495pp
Countries
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6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Nov 2026 to Mar 2028
Interests: Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 105
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Dec 2026 to Feb 2028
Interests: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,190
Save 275
Per Person
View Trip
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Nov 2026 to Mar 2028
Interests:
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 161
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$7,750
Suite
$14,143
From (Per Person)
A$7,750
Save 272
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Jan 2029
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$10,692
Suite
$18,093
From (Per Person)
A$10,692
Save 460
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ship: Le Bellot
Departure: 08 December 2026
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$13,922
Suite
$20,208
From (Per Person)
A$13,922
Save 388
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Jan 2027 to Mar 2029
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$10,692
Suite
$17,996
From (Per Person)
A$10,692
Save 348
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville
Departures: Jan 2027 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$11,080
Suite
$18,510
From (Per Person)
A$11,080
Save 1,140
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ship: Le Bellot
Departure: 17 December 2028
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$10,712
Suite
$18,113
From (Per Person)
A$10,712
Save 288
Per Person
View Trip
14 Day Magic of Colombia (MedellÍn & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

14 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Nov 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,892
Suite
$12,690
From (Per Person)
A$8,892
Save 1,879
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Jan 2027 to Jan 2028
Interests: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,777
Save 422
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Nov 2026 to Dec 2028
Interests: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,787
Save 224
Per Person
View Trip
11 Day Magic of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Barranquilla to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Nov 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,044
Suite
$10,276
From (Per Person)
A$8,044
Save 1,785
Per Person
View Trip
16 Day Wonders of Colombia (MedellÍn, Cartagena & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

16 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Nov 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$12,388
Suite
$13,921
From (Per Person)
A$12,388
Save 1,929
Per Person
View Trip
11 Day Wonders of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Cartagena to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Nov 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,564
Suite
$10,276
From (Per Person)
A$8,564
Save 1,785
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Jan 2027 to Jan 2028
Interests: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,631
Save 236
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: May 2027 to Dec 2027
Interests: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 130
Per Person
View Trip
7 Day Callao (Lima) to Fuerte Amador with Crystal Cruises
Cruise

7 Days (6 Nights) Lima to Panama City
Operator: Crystal
Ship: Crystal Serenity
Departure: 05 December 2027
Visits: Peru, Ecuador, Panama
Exclusive Savings
Oceanview
$4,714
Balcony
$5,574
Suite
$5,488
From (Per Person)
A$4,714
Save 686
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Dec 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,298
Oceanview
$1,483
Balcony
$2,063
Suite
$2,473
From (Per Person)
A$1,298
Save 1,905
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Dec 2026 to Jan 2027
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$2,056
Oceanview
$2,232
Balcony
$2,680
Suite
$2,914
From (Per Person)
A$2,056
Save 1,410
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Dec 2026 to Jan 2027
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,393
Oceanview
$1,652
Balcony
$2,891
Suite
$4,430
From (Per Person)
A$1,393
Save 1,502
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,359
Oceanview
$1,531
Balcony
$2,179
Suite
$2,539
From (Per Person)
A$1,359
Save 1,536
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,386
Oceanview
$1,473
Balcony
$2,050
Suite
$2,533
From (Per Person)
A$1,386
Save 1,182
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,423
Oceanview
$1,562
Balcony
$2,113
Suite
$2,567
From (Per Person)
A$1,423
Save 1,379
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Island Princess
Departure: 28 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
-
Oceanview
$3,033
Balcony
$4,128
Suite
-
From (Per Person)
A$3,033
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Island Princess
Departure: 13 December 2027
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$1,814
Oceanview
$1,952
Balcony
$2,982
Suite
$4,308
From (Per Person)
A$1,814
Per Person
View Trip
16 Day Panama Canal Holiday with Holland America
Cruise
 (5)

16 Days (15 Nights) San Diego to Miami
Operator: Holland America
Ship: Zaandam
Departure: 18 December 2027
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
$4,153
Oceanview
$4,608
Balcony
$7,677
Suite
$14,736
From (Per Person)
A$4,153
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Island Princess
Departure: 12 December 2026
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$1,636
Oceanview
$1,966
Balcony
$2,091
Suite
-
From (Per Person)
A$1,636
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (12)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Crown Princess
Departure: 03 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Curacao
Exclusive Savings
Inside
$1,898
Oceanview
$2,092
Balcony
$3,229
Suite
-
From (Per Person)
A$1,898
Per Person
View Trip
11 Day A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Miami to Miami
Operator: Explora Journeys
Ship: Explora II
Departure: 02 December 2027
Visits: USA, Jamaica, Panama, Costa Rica, Colombia
Exclusive Savings
Suite
$8,369
From (Per Person)
A$8,369
Save 171
Per Person
View Trip
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