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Panama Tours & Cruises Starting In December 2026, 2027 and 2028

Are you planning a tour to Panama in December 2026, 2027 or 2028? Choose from 76 unique cruises, small group tours and adventures with 856 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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76 Trips (856 Departures)
76 Trips (856 Departures)
Departures
Duration
6 Days
171 Days
Types
Budget
Start & End Cities
Operators
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Price
$1,000pp
$147,495pp
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9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 161
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Nov 2026 to Feb 2028
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,102
Save 437
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 105
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$7,750
Suite
$14,143
From (Per Person)
A$7,750
Save 272
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ship: Le Bellot
Departure: 18 December 2026
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$14,698
Suite
$22,420
From (Per Person)
A$14,698
Save 412
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$10,789
Suite
$17,996
From (Per Person)
A$10,789
Save 433
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$11,080
Suite
$18,510
From (Per Person)
A$11,080
Save 1,140
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Dec 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,469
Save 530
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Dec 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,812
Save 219
Per Person
View Trip
14 Day Magic of Colombia (MedellÍn & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

14 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$9,120
Suite
$12,690
From (Per Person)
A$9,120
Save 1,879
Per Person
View Trip
11 Day Magic of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Barranquilla to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,044
Suite
$10,276
From (Per Person)
A$8,044
Save 1,785
Per Person
View Trip
11 Day Wonders of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Cartagena to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,184
Suite
$10,276
From (Per Person)
A$8,184
Save 1,781
Per Person
View Trip
16 Day Wonders of Colombia (MedellÍn, Cartagena & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

16 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$11,829
Suite
$13,921
From (Per Person)
A$11,829
Save 1,925
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Dec 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,645
Save 954
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Apr 2027 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 130
Per Person
View Trip
7 Day Callao (Lima) to Fuerte Amador with Crystal Cruises
Cruise

7 Days (6 Nights) Lima to Panama City
Operator: Crystal
Ship: Crystal Serenity
Departure: 05 December 2027
Visits: Peru, Ecuador, Panama
Exclusive Savings
Oceanview
$4,800
Balcony
$5,677
Suite
$5,589
From (Per Person)
A$4,800
Save 600
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Dec 2026 to Jan 2027
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,492
Oceanview
$1,795
Balcony
$3,294
Suite
$4,048
From (Per Person)
A$1,821
Save 1,603
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Oct 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,484
Oceanview
$1,614
Balcony
$2,015
Suite
$2,419
From (Per Person)
A$1,484
Save 3,345
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Dec 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,369
Oceanview
$1,500
Balcony
$2,009
Suite
$2,514
From (Per Person)
A$1,369
Save 1,970
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,386
Oceanview
$1,502
Balcony
$2,065
Suite
$2,589
From (Per Person)
A$1,386
Save 899
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,506
Oceanview
$1,603
Balcony
$2,113
Suite
$2,585
From (Per Person)
A$1,506
Save 1,009
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Dec 2026 to Jan 2027
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,832
Oceanview
$1,838
Balcony
$2,431
Suite
$2,770
From (Per Person)
A$2,253
Save 1,540
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (12)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Crown Princess
Departure: 03 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Curacao
Exclusive Savings
Inside
$1,761
Oceanview
$1,824
Balcony
$3,196
Suite
$5,497
From (Per Person)
A$1,761
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Island Princess
Departure: 28 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$3,195
Oceanview
$3,334
Balcony
$3,433
Suite
$5,690
From (Per Person)
A$3,195
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Island Princess
Departure: 13 December 2027
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$1,888
Oceanview
$2,046
Balcony
$3,007
Suite
$4,997
From (Per Person)
A$1,888
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Island Princess
Departure: 12 December 2026
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,047
Oceanview
$2,047
Balcony
$3,057
Suite
$5,655
From (Per Person)
A$2,047
Per Person
View Trip
11 Day A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Miami to Miami
Operator: Explora Journeys
Ship: Explora II
Departure: 02 December 2027
Visits: USA, Jamaica, Panama, Costa Rica, Colombia
Exclusive Savings
Suite
$8,060
From (Per Person)
A$8,060
Save 165
Per Person
View Trip
16 Day Panama Canal Holiday with Holland America
Cruise
 (5)

16 Days (15 Nights) San Diego to Miami
Operator: Holland America
Ship: Zaandam
Departure: 18 December 2027
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,153
Oceanview
$4,608
Balcony
$7,677
Suite
$14,736
From (Per Person)
A$4,153
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Panama City to Fort Lauderdale
Operator: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: Panama, Costa Rica, Belize, Mexico, USA
Exclusive Savings
Balcony
$8,129
Suite
$11,461
From (Per Person)
A$8,129
Save 196
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Fort Lauderdale to Panama City
Operator: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: USA, Mexico, Belize, Costa Rica, Panama
Exclusive Savings
Balcony
$8,129
Suite
$11,461
From (Per Person)
A$8,129
Save 184
Per Person
View Trip
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