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Panama Tours & Cruises Starting In December 2026, 2027 and 2028

Are you planning a tour to Panama in December 2026, 2027 or 2028? Choose from 59 unique cruises, small group tours and adventures with 776 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveler reviews to find the Panama tour that best matches your travel style, budget and dates.
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59 Trips (776 Trip Departures)
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operated By: G Adventures
Departures: Mar 2026 to Jan 2028
Visit: Panama
Great Adventure Sale
G's February Sale
Exclusive Savings
From
US$764
Save 135
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operated By: Globus
Departures: Feb 2026 to Mar 2027
Trip Styles: Short Break, Scenic
Visit: Panama
Exclusive Savings
From
US$1,689
Save 89
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operated By: G Adventures
Departures: Jun 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Great Adventure Sale
G's February Sale
Exclusive Savings
From
US$1,689
Save 360
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Dec 2026 to Mar 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$9,010
Suite
$14,480
From
US$9,010
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Jan 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$9,500
Suite
$15,340
From
US$9,500
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Feb 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,719
Save 440
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operated By: G Adventures
Departures: May 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Great Adventure Sale
G's February Sale
Exclusive Savings
From
US$1,019
Save 180
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operated By: G Adventures
Departures: Jun 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama, Colombia
Great Adventure Sale
Exclusive Savings
From
US$3,491
Save 565
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Apr 2028
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$868
Oceanview
$998
Balcony
$1,190
Suite
$1,437
From
US$868
Save 632
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 20 December 2026
Visit: Colombia, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,315
Oceanview
$1,326
Balcony
$1,658
Suite
$1,638
From
US$1,315
Save 648
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$797
Oceanview
$907
Balcony
$1,253
Suite
$1,316
From
US$797
Save 717
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$674
Oceanview
$739
Balcony
$1,014
Suite
$1,107
From
US$674
Save 703
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Mar 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$821
Oceanview
$909
Balcony
$1,114
Suite
$1,221
From
US$821
Save 836
Per Person
View Trip
8 Day Southern Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 19 December 2026
Visit: Panama, Colombia, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$954
Oceanview
$984
Balcony
$1,537
Suite
$1,707
From
US$954
Save 528
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 28 December 2026
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,379
Oceanview
$1,499
Balcony
$2,199
Suite
$3,199
From
US$1,379
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 13 December 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,449
Oceanview
$1,649
Balcony
$2,249
Suite
$3,695
From
US$1,449
Per Person
View Trip
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise
 (5)

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama, Costa Rica
Viking $499 Air Deal
Inside
-
Oceanview
-
Balcony
$6,399
Suite
$11,999
From
US$6,399
Per Person
View Trip
11 Day A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 December 2027
Visit: USA, Jamaica, Panama, Costa Rica, Colombia
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$5,215
Suite
$5,880
From
US$5,215
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 12 December 2026
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,399
Oceanview
$1,499
Balcony
$2,099
Suite
$3,149
From
US$1,399
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Crown Princess
Departure: 03 December 2026
Visit: USA, Mexico, Costa Rica, Panama, Curacao
Princess Standard
Inside
$1,429
Oceanview
$1,759
Balcony
$2,129
Suite
$3,229
From
US$1,429
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Fare Saver
Inside
$2,324
Oceanview
$2,374
Balcony
$4,652
Suite
-
From
US$2,324
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2026 to Dec 2026
Visit: Panama, Costa Rica, Honduras, Belize, Mexico, USA
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,399
Suite
$5,999
From
US$3,399
Save 200
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$4,099
Suite
$6,799
From
US$4,099
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 December 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,649
Oceanview
$1,849
Balcony
$2,449
Suite
$3,891
From
US$1,649
Per Person
View Trip
17 Day Panama Canal Cruise From Miami To San Diego with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Miami to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 04 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$2,029
Oceanview
$2,079
Balcony
$3,719
Suite
$4,078
From
US$2,029
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$8,400
Balcony
$10,400
Suite
$20,060
From
US$8,400
Save 2,100
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Feb 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$3,411
Save 1,121
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 23 December 2027
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,400
Oceanview
$1,549
Balcony
$2,400
Suite
$3,050
From
US$1,400
Per Person
View Trip
13 Day Caribbean with Costa Rica & Panama Canal Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Dec 2026 to Dec 2026
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,149
Oceanview
$1,209
Balcony
$1,549
Suite
$2,499
From
US$1,149
Per Person
View Trip
23 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

23 Days (22 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 23 December 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$2,718
Oceanview
$2,970
Balcony
$3,688
Suite
-
From
US$2,718
Save 66
Per Person
View Trip
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