Home > Tours > Latin America Tours > Central America Tours > Panama Tours & Cruises > December

Panama Tours & Cruises Starting In December 2026, 2027 and 2028

Are you planning a tour to Panama in December 2026, 2027 or 2028? Choose from 62 unique cruises, small group tours and adventures with 700 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveler reviews to find the Panama tour that best matches your travel style, budget and dates.
Filter Results
Departures
Duration
6 Days
171 Days
Types
Budget
Start & End Cities
Operators
Show More...
Price
$500pp
$239,198pp
Countries
Show More...
Filter Results
62 Trips (700 Trip Departures)
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Visit: Panama
Exclusive Savings
From
US$809
Save 100
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operated By: Globus
Departures: Jun 2026 to Mar 2027
Trip Styles: Short Break, Scenic
Visit: Panama
From
US$1,759
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$7,790
Suite
$13,140
From
US$7,790
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,970
Suite
$10,140
From
US$5,970
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$6,040
Suite
$10,060
From
US$6,040
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,738
Save 374
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,124
Save 125
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
From
US$2,099
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operated By: G Adventures
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama, Colombia
From
US$3,999
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jun 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$831
Oceanview
$894
Balcony
$1,172
Suite
$1,160
From
US$831
Save 913
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$888
Oceanview
$997
Balcony
$1,400
Suite
$1,425
From
US$888
Save 828
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$915
Oceanview
$1,055
Balcony
$1,488
Suite
$1,512
From
US$915
Save 721
Per Person
View Trip
8 Day Southern Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 19 December 2026
Visit: Panama, Colombia, Aruba, Bonaire
Exclusive Savings
Inside
$926
Oceanview
$926
Balcony
$1,420
Suite
$1,462
From
US$926
Save 685
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Mar 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$943
Oceanview
$1,037
Balcony
$1,337
Suite
$1,437
From
US$943
Save 1,422
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 20 December 2026
Visit: Colombia, Aruba, Bonaire, Panama
Exclusive Savings
Inside
$1,680
Oceanview
$1,691
Balcony
$2,385
Suite
$2,303
From
US$1,680
Save 840
Per Person
View Trip
11 Day A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 December 2027
Visit: USA, Jamaica, Panama, Costa Rica, Colombia
Inside
-
Oceanview
-
Balcony
-
Suite
$5,350
From
US$5,350
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 13 December 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,299
Oceanview
$1,499
Balcony
$1,999
Suite
$3,499
From
US$1,299
Per Person
View Trip
16 Day Panama Canal Holiday with Holland America
Cruise
 (4)

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 December 2027
Visit: USA, Mexico, Costa Rica, Panama, Colombia
Book Early & Have It All Fare Option
Inside
$2,674
Oceanview
$2,974
Balcony
$4,974
Suite
$9,574
From
US$2,674
Per Person
View Trip
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise
 (5)

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama, Costa Rica
Viking $499 Air Deal
Inside
-
Oceanview
-
Balcony
$6,599
Suite
$11,999
From
US$6,599
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (9)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Crown Princess
Departure: 03 December 2026
Visit: USA, Mexico, Costa Rica, Panama, Curacao
Princess Standard
Inside
$999
Oceanview
$1,489
Balcony
$1,829
Suite
$2,399
From
US$999
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 28 December 2026
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,842
Oceanview
$1,939
Balcony
$2,299
Suite
$2,709
From
US$1,842
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 12 December 2026
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,349
Oceanview
$1,489
Balcony
$1,497
Suite
$1,819
From
US$1,349
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$4,399
Suite
$6,799
From
US$4,399
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (4)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Fare Saver
Inside
$1,799
Oceanview
$1,899
Balcony
$4,699
Suite
-
From
US$1,799
Per Person
View Trip
17 Day Panama Canal Cruise From Miami To San Diego with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Miami to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 04 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$1,659
Oceanview
$1,769
Balcony
$3,489
Suite
$3,569
From
US$1,659
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 December 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,499
Oceanview
$1,679
Balcony
$2,149
Suite
$3,709
From
US$1,499
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2026 to Dec 2026
Visit: Panama, Costa Rica, Honduras, Belize, Mexico, USA
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,999
Suite
$6,499
From
US$3,999
Save 200
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$3,516
Save 952
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Dec 2026 to Dec 2026
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,049
Oceanview
$1,194
Balcony
$1,479
Suite
$2,239
From
US$1,049
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$12,800
Balcony
$13,800
Suite
$23,100
From
US$12,800
Per Person
View Trip
Results: 1-30 of 62

No trips found. Try adjusting the search filters.




Trips found! Scroll up to view.

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

Travel Styles

18-30's Tours Active Adventures Coach Tours Festivals & Events Small Group Tours

Trip Lengths

1 Month 10 Day 2 Week 3 Week

Departure Months

May June July August September October November December January February March April

Countries

Chile Colombia Costa Rica Peru

Cities

Tours from San Jose

Routes

Tours from Los Angeles to San Francisco Tours from Los Angeles to Los Angeles

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations