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Panama Tours & Cruises Starting In January 2027 and 2028

Are you planning a tour to Panama in January 2027 or 2028? Choose from 125 unique cruises, small group tours and adventures with 813 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveler reviews to find the Panama tour that best matches your travel style, budget and dates.
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125 Trips (813 Trip Departures)
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operated By: Globus
Departures: Apr 2026 to Mar 2027
Trip Styles: Short Break, Scenic
Visit: Panama
From
US$1,759
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operated By: G Adventures
Departures: Jun 2026 to Jan 2028
Visit: Panama
Exclusive Savings
From
US$674
Save 225
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Jan 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$9,500
Suite
$15,340
From
US$9,500
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operated By: G Adventures
Departures: Jun 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Exclusive Savings
From
US$959
Save 240
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operated By: G Adventures
Departures: Jun 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,979
Save 220
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Apr 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,710
Save 570
Per Person
View Trip
8 Day Coastal Adventures: Panama & Costa Rica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Panama City to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 24 January 2028
Visit: Panama, Costa Rica
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$5,460
Balcony
-
Suite
$7,035
From
US$5,460
Save 1,635
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$6,320
Suite
$10,750
From
US$6,320
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Dec 2026 to Mar 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$8,530
Suite
$14,480
From
US$8,530
Per Person
View Trip
12 Day The Panama Canal & Costa Rica - Eastbound with Tauck
Tour + Cruise

12 Days Puntarenas to Panama City
Operated By: Tauck
Ship: Le Lapérouse
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Costa Rica, Panama
From
US$9,290
Per Person
View Trip
12 Day The Panama Canal & Costa Rica - Westbound with Tauck
Tour + Cruise

12 Days Panama City to San Jose
Operated By: Tauck
Ship: Le Lapérouse
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Panama, Costa Rica
From
US$9,290
Per Person
View Trip
14 Day Cycle Nicaragua to the Panama Canal with Explore Worldwide
Tour

14 Days Granada to Panama City
Operated By: Explore Worldwide
Departures: Oct 2026 to Nov 2027
Trip Styles: Adventure, Small Group, Cycling
Visit: Nicaragua, Costa Rica, Panama
From
US$5,050
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operated By: G Adventures
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama, Colombia
From
US$3,999
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 09 January 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$898
Oceanview
$1,028
Balcony
$1,448
Suite
$1,488
From
US$898
Save 508
Per Person
View Trip
11 Day Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao) with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Panama City to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 14 January 2028
Visit: Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$3,239
Oceanview
$3,799
Balcony
$4,669
Suite
$6,839
From
US$3,239
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$868
Oceanview
$998
Balcony
$1,408
Suite
$1,422
From
US$868
Save 701
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$866
Oceanview
$997
Balcony
$1,406
Suite
$1,436
From
US$866
Save 572
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$815
Oceanview
$825
Balcony
$1,172
Suite
$1,080
From
US$815
Save 934
Per Person
View Trip
13 Day World Cruise: Panama Canal To Callao with Seabourn
Cruise
 (1)

13 Days (12 Nights) Miami to Lima
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru
Yours to Explore
Inside
-
Oceanview
$6,514
Balcony
$7,599
Suite
$16,299
From
US$6,514
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$839
Oceanview
$949
Balcony
$1,329
Suite
$1,348
From
US$839
Save 542
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Mar 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$866
Oceanview
$994
Balcony
$1,197
Suite
$1,164
From
US$866
Save 1,114
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 08 January 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$861
Oceanview
$981
Balcony
$1,371
Suite
$1,390
From
US$861
Save 482
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$841
Oceanview
$951
Balcony
$1,330
Suite
$1,350
From
US$841
Save 760
Per Person
View Trip
18 Day New York To Los Angeles with Cunard
Cruise
 (1)

18 Days (17 Nights) New York to Los Angeles
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 January 2027
Visit: USA, Aruba, Panama, El Salvador, Mexico
Bonus Onboard Credit
Inside
$2,599
Oceanview
$3,559
Balcony
$4,269
Suite
-
From
US$2,599
Per Person
View Trip
24 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

24 Days (23 Nights) Fort Lauderdale to Honolulu
Cruise Line: Princess
Ship: Coral Princess
Departure: 06 January 2027
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$3,092
Oceanview
$3,409
Balcony
$5,625
Suite
-
From
US$3,092
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,567
Oceanview
$1,877
Balcony
$2,921
Suite
$3,777
From
US$1,567
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (9)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ships: Crown Princess, Emerald Princess (+3 more), Grand Princess, Island Princess, Sapphire Princess
Departures: Apr 2026 to Apr 2028
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,327
Oceanview
$1,559
Balcony
$2,149
Suite
$3,257
From
US$1,327
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 30 January 2027
Visit: Panama, Colombia, Curacao, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$1,184
Oceanview
$1,280
Balcony
$1,663
Suite
$1,663
From
US$1,184
Save 619
Per Person
View Trip
16 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

16 Days (15 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Coral Princess
Departure: 06 January 2027
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,702
Oceanview
$1,961
Balcony
$2,766
Suite
$3,792
From
US$1,702
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2027 to Jan 2028
Visit: Panama, Costa Rica, Belize, Mexico, USA
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$6,499
From
US$3,799
Per Person
View Trip
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