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Panama Tours & Cruises Starting In December 2026, 2027 and 2028

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171 Days
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$174,198pp
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54 Trips (785 Trip Departures)
23 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

23 Days (22 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 23 December 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$2,718
Oceanview
$2,970
Balcony
$3,688
Suite
-
From
US$2,718
Save 66
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,036
Suite
$10,771
From
US$10,036
Save 17,362
Per Person
View Trip
16 Day Antilles To Andes with Oceania Cruises
Cruise
 (1)

16 Days (15 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia, Panama, Ecuador, Peru
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,600
Oceanview
$3,765
Balcony
$5,042
Suite
$7,310
From
US$3,600
Save 4,998
Per Person
View Trip
13 Day Caribbean with Costa Rica & Panama Canal with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 05 December 2026
Visit: USA, Cayman Islands, Jamaica, Colombia, Panama, Costa Rica, Bahamas
Princess Standard
Inside
$1,179
Oceanview
$1,309
Balcony
$1,479
Suite
$2,479
From
US$1,179
Per Person
View Trip
13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise
 (3)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departures: Oct 2026 to Mar 2027
Visit: USA, Bahamas, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Fare Saver
Inside
$1,219
Oceanview
$1,419
Balcony
$2,019
Suite
$4,154
From
US$1,219
Per Person
View Trip
19 Day Panama Canal Cruise: Colombia, Costa Rica & Mexico with Azamara Cruises
Cruise
 (4)

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 18 December 2026
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Azamara Always Included
Exclusive Savings
Inside
$4,980
Oceanview
$5,736
Balcony
$6,260
Suite
$10,179
From
US$4,980
Save 99
Per Person
View Trip
15 Day Panama Canal & Central America with Viking Cruises
Cruise
 (8)

15 Days (14 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2026 to Feb 2028
Visit: USA, Jamaica, Panama, Costa Rica, Honduras, Belize, Mexico
Flights Included
Viking $499 Air Deal
Inside
-
Oceanview
-
Balcony
$4,999
Suite
$7,999
From
US$4,999
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 02 December 2027
Visit: USA, Dominican Republic, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,300
Oceanview
$1,489
Balcony
$1,450
Suite
$2,750
From
US$1,300
Per Person
View Trip
12 Day Central America From Miami To Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Jewel, Norwegian Sun
Departures: Mar 2026 to Dec 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Belize, Mexico
Inside
$1,439
Oceanview
$1,749
Balcony
$2,905
Suite
$3,215
From
US$1,439
Per Person
View Trip
45 Day Best of Central America with Intrepid Travel
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operated By: Intrepid Travel
Departures: Mar 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$6,097
Save 1,493
Per Person
View Trip
62 Day Total Central America: Two Months of Wild with G Adventures
New ReleaseTour

62 Days Mexico City to Panama City
Operated By: G Adventures
Departures: Apr 2026 to Oct 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Guatemala, Mexico, Nicaragua, Panama (+4 more), Belize, Honduras, Costa Rica, El Salvador
Exclusive Savings
From
US$6,013
Save 214
Per Person
View Trip
13 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sun
Departures: Dec 2026 to Mar 2027
Visit: USA, Bahamas, Dominican Republic, Aruba (+4 more), Curacao, Colombia, Panama, Costa Rica
Exclusive Savings
Inside
$1,919
Oceanview
$2,343
Balcony
$3,759
Suite
$4,874
From
US$1,919
Save 70
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operated By: Intrepid Travel
Departures: Mar 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$8,377
Save 1,929
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visit: USA, Mexico, Guatemala, Belize (+5 more), Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,245
Suite
$9,882
From
US$9,245
Save 16,553
Per Person
View Trip
20 Day Panama Canal Holiday: Amber Cove & Costa Rica with Holland America
Cruise
 (3)

20 Days (19 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 20 December 2026
Visit: USA, Bahamas, Turks and Caicos Islands, Dominican Republic (+5 more), Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Fare Saver
Inside
$2,819
Oceanview
$3,149
Balcony
$4,093
Suite
$7,817
From
US$2,819
Per Person
View Trip
22 Day Panama Canal & Southern Caribbean: ABC Islands with Holland America
Cruise
 (3)

22 Days (21 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departures: Dec 2026 to Feb 2027
Visit: USA, Bahamas, Aruba, Colombia (+5 more), Panama, Costa Rica, Cayman Islands, Bonaire, Curacao
Fare Saver
Inside
$2,694
Oceanview
$2,974
Balcony
$3,874
Suite
$7,696
From
US$2,694
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 12 December 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Aruba, Curacao, Bonaire, Dominican Republic
Bonus Onboard Credit
Exclusive Savings
Inside
$2,682
Oceanview
$2,953
Balcony
$3,487
Suite
-
From
US$2,682
Save 62
Per Person
View Trip
37 Day Caribbean To Cape Horn with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$10,002
Oceanview
$10,633
Balcony
$14,076
Suite
$20,430
From
US$10,002
Save 10,396
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Oct 2026 to Dec 2027
Visit: USA, Bonaire, Aruba, Curacao (+7 more), Dominican Republic, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$1,934
Oceanview
$2,308
Balcony
$2,643
Suite
$11,717
From
US$1,934
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 13 December 2026
Visit: USA, Cayman Islands, Jamaica, Curacao (+7 more), Bonaire, Aruba, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$2,754
Oceanview
$2,987
Balcony
$3,472
Suite
$13,308
From
US$2,754
Save 65
Per Person
View Trip
29 Day Caribbean, Central America & Peru Cruise: Aruba, Miami & Panama Canal with Azamara Cruises
Cruise
 (4)

29 Days (28 Nights) Bridgetown to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 27 December 2027
Visit: Barbados, Bonaire, Curacao, Aruba (+11 more), Dominican Republic, Bahamas, USA, Mexico, Belize, Honduras, Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$8,979
Oceanview
$10,570
Balcony
$12,878
Suite
$18,824
From
US$8,979
Save 210
Per Person
View Trip
26 Day Ultimate Island Holiday with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 19 December 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Barthelemy (+14 more), Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Saint Lucia, Barbados, Grenada, Aruba, Bonaire, Curacao, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,529
Suite
$17,489
From
US$15,529
Save 25,069
Per Person
View Trip
143 Day Viking World Cruise with Viking Cruises
Cruise
 (5)

143 Days (142 Nights) Fort Lauderdale to London
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama (+28 more), Costa Rica, French Polynesia, Cook Islands, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Kenya, Tanzania, Madagascar, Mozambique, South Africa, Namibia, Angola, Nigeria, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$62,995
Suite
$119,995
From
US$62,995
Save 2,000
Per Person
View Trip
171 Day Viking World Voyage III with Viking Cruises
Cruise
 (5)

171 Days (170 Nights) Fort Lauderdale to Stockholm
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama (+38 more), Costa Rica, French Polynesia, Cook Islands, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Kenya, Tanzania, Madagascar, Mozambique, South Africa, Namibia, Angola, Nigeria, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England, Ireland, Wales, Northern Ireland, Scotland, Norway, Denmark, Germany, Poland, Estonia, Sweden
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$79,995
Suite
$149,995
From
US$79,995
Save 2,000
Per Person
View Trip
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