Home > Tours > Latin America Tours > Central America Tours > Panama Tours & Cruises > December

Panama Tours & Cruises Starting In December 2026, 2027 and 2028

Filter Results
72 Trips (738 Departures)
72 Trips (738 Departures)
Departures
Duration
6 Days
171 Days
Types
Budget
Start & End Cities
Operators
Show More...
Price
$900pp
$147,495pp
Countries
Show More...
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Operator: Princess
Ship: Island Princess
Departure: 12 December 2026
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,047
Oceanview
$2,047
Balcony
$3,057
Suite
$8,561
From (Per Person)
A$2,047
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Oct 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,487
Oceanview
$1,621
Balcony
$2,090
Suite
$2,357
From (Per Person)
A$1,487
Save 3,287
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,432
Oceanview
$1,502
Balcony
$2,137
Suite
$2,524
From (Per Person)
A$1,432
Save 1,273
Per Person
View Trip
13 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Sun
Departures: Dec 2026 to Mar 2027
Visits: USA, Bahamas, Dominican Republic, Aruba +4 more, Curacao, Colombia, Panama, Costa Rica
Just Cruise Fare
Exclusive Savings
Inside
$2,187
Oceanview
$2,684
Balcony
$4,121
Suite
$6,063
From (Per Person)
A$2,187
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Oct 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$14,548
Save 494
Per Person
View Trip
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Operator: Viking
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2028
Visits: USA, Mexico, Colombia, Panama, Costa Rica
Exclusive Savings
Balcony
$9,648
Suite
$20,379
From (Per Person)
A$9,648
Save 1,447
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Operator: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visits: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Balcony
$15,163
Suite
$16,196
From (Per Person)
A$15,163
Save 7,887
Per Person
View Trip
143 Day Viking World Cruise with Viking Cruises
Cruise

143 Days (142 Nights) Fort Lauderdale to London
Operator: Viking
Ship: Viking Vesta
Departures: Dec 2027 to Dec 2028
Visits: USA, Mexico, Colombia, Panama +29 more, Costa Rica, French Polynesia, Cook Islands, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Kenya, Tanzania, Zanzibar, Madagascar, Mozambique, South Africa, Namibia, Angola, Nigeria, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Exclusive Savings
Balcony
$115,635
Suite
$195,995
From (Per Person)
A$115,635
Save 2,470
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Fort Lauderdale to Panama City
Operator: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: USA, Mexico, Belize, Costa Rica, Panama
Exclusive Savings
Balcony
$8,129
Suite
$11,461
From (Per Person)
A$8,129
Save 180
Per Person
View Trip
12 Day Fuerte Amador (Panama City) to Fort Lauderdale with Crystal Cruises
New ReleaseCruise

12 Days (11 Nights) Panama City to Fort Lauderdale
Operator: Crystal
Ship: Crystal Serenity
Departure: 11 December 2027
Visits: Panama, Costa Rica, Honduras, Guatemala, Belize, Mexico, USA
Exclusive Savings
Oceanview
$6,977
Balcony
$8,644
Suite
$9,083
From (Per Person)
A$6,977
Save 1,723
Per Person
View Trip
25 Day Panama Canal & Eastern Caribbean Discovery with Holland America
Cruise

25 Days (24 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Volendam
Departure: 11 December 2027
Visits: USA, Bahamas, Curacao, Colombia +9 more, Panama, Costa Rica, Cayman Islands, Saint Martin, Martinique, Barbados, Trinidad and Tobago, Saint Lucia, Saint Kitts and Nevis
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$6,578
Oceanview
$7,806
Balcony
$11,647
Suite
$21,923
From (Per Person)
A$6,578
Per Person
View Trip
13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Volendam
Departure: 11 December 2027
Visits: USA, Bahamas, Curacao, Colombia, Panama, Costa Rica, Cayman Islands
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,494
Oceanview
$4,108
Balcony
$5,801
Suite
$9,632
From (Per Person)
A$3,494
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$5,077
Save 1,018
Per Person
View Trip
15 Day Holidays On The Canal with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 December 2028
Visits: USA, Mexico, Belize, Honduras +5 more, Costa Rica, Panama, Jamaica, Dominican Republic, Bahamas
Exclusive Savings
Balcony
$13,472
Suite
$14,803
From (Per Person)
A$13,472
Save 7,818
Per Person
View Trip
11 Day Cartagena to Puntarenas with Crystal Cruises
New ReleaseCruise

11 Days (10 Nights) Cartagena to Puntarenas
Operator: Crystal
Ship: Crystal Serenity
Departure: 02 December 2026
Visits: Colombia, Curacao, Bonaire, Aruba, Panama, Costa Rica
Exclusive Savings
Oceanview
$7,155
Balcony
$8,422
Suite
$9,105
From (Per Person)
A$7,155
Save 1,145
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Nov 2026 to Feb 2028
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,102
Save 397
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,890
Save 105
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Panama City to Fort Lauderdale
Operator: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: Panama, Costa Rica, Belize, Mexico, USA
Exclusive Savings
Balcony
$8,129
Suite
$11,461
From (Per Person)
A$8,129
Save 196
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Dec 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,788
Save 217
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Nov 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,665
Save 334
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visits: USA, Mexico, Guatemala, Belize +5 more, Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Balcony
$14,081
Suite
$14,798
From (Per Person)
A$14,081
Save 8,349
Per Person
View Trip
171 Day Viking World Voyage III with Viking Cruises
Cruise

171 Days (170 Nights) Fort Lauderdale to Stockholm
Operator: Viking
Ship: Viking Vesta
Departures: Dec 2027 to Dec 2028
Visits: USA, Mexico, Colombia, Panama +39 more, Costa Rica, French Polynesia, Cook Islands, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Kenya, Tanzania, Zanzibar, Madagascar, Mozambique, South Africa, Namibia, Angola, Nigeria, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England, Ireland, Wales, Northern Ireland, Scotland, Norway, Denmark, Germany, Poland, Estonia, Sweden
Exclusive Savings
Balcony
$140,135
Suite
$238,135
From (Per Person)
A$140,135
Save 2,950
Per Person
View Trip
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,393
Save 161
Per Person
View Trip
30 Day Holiday Harbors & Hollywood with Oceania Cruises
Cruise

30 Days (29 Nights) Miami to Los Angeles
Operator: Oceania
Ship: Oceania Sonata
Departure: 06 December 2027
Visits: USA, Aruba, Curacao, Bonaire +11 more, Grenada, Barbados, Saint Lucia, Guadeloupe, Virgin Islands, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Inclusions
Exclusive Savings
Balcony
$19,882
Suite
$27,816
From (Per Person)
A$19,882
Save 2,498
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Princess
Ship: Caribbean Princess
Departure: 02 December 2027
Visits: USA, Dominican Republic, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Exclusive Savings
Inside
$1,527
Oceanview
$1,610
Balcony
$2,497
Suite
$3,467
From (Per Person)
A$1,527
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Operator: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visits: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Oceanview
-
Balcony
$19,257
Suite
$29,449
From (Per Person)
A$19,257
Save 393
Per Person
View Trip
13 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Miami to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 21 December 2027
Visits: USA, Bahamas, Dominican Republic, Aruba +4 more, Curacao, Colombia, Panama, Cayman Islands
Just Cruise Fare
Exclusive Savings
Inside
$4,094
Oceanview
$4,839
Balcony
$6,774
Suite
$7,667
From (Per Person)
A$4,094
Per Person
View Trip
26 Day Merry Mexico & Canal Crossing with Oceania Cruises
Cruise

26 Days (25 Nights) Los Angeles to Miami
Operator: Oceania
Ship: Oceania Sonata
Departure: 03 December 2028
Visits: USA, Mexico, Guatemala, Costa Rica +6 more, Panama, Colombia, Bahamas, Honduras, Belize, Cayman Islands
Your World Inclusions
Exclusive Savings
Balcony
$17,367
Suite
$23,721
From (Per Person)
A$17,367
Save 2,493
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,664
Save 1,135
Per Person
View Trip
12 Day Central America From Miami To Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Operator: Norwegian Cruise Line
Ships: Norwegian Jewel, Norwegian Sun
Departures: Feb 2027 to Dec 2027
Visits: USA, Cayman Islands, Colombia, Panama, Costa Rica, Belize, Mexico
Just Cruise Fare
Exclusive Savings
Inside
$2,119
Oceanview
$2,191
Balcony
$3,297
Suite
$5,522
From (Per Person)
A$2,119
Per Person
View Trip
Results: 31-60 of 72

No trips found. Try adjusting the search filters.




Trips found! Scroll up to view.

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

Travel Styles

18-30's Tours Active Adventures Festivals & Events Small Group Tours

Trip Lengths

1 Month 10 Day 2 Week 3 Week 4 Week

Departure Months

September October November December January February March April May June July August

Countries

Chile Colombia Costa Rica Ecuador Panama Peru

Cities

Tours from Cartagena Tours from Lima Tours from San Jose Tours from Santiago Tours from Santiago

Routes

Tours from Auckland to Auckland Tours from Barcelona to Lisbon Tours from Buenos Aires to Buenos Aires Tours from Cape Town to Cape Town Tours from Lima to Lima Tours from Lima to Buenos Aires Tours from London to Rome Tours from London to London Tours from Los Angeles to San Francisco Tours from Los Angeles to Los Angeles Tours from New York to Los Angeles Tours from New York to New York Tours from Playa Del Carmen to Antigua Tours from Rome to London Tours from Rome to Rome Tours from San Francisco to Los Angeles Tours from San Francisco to San Francisco Tours from San Jose to San Jose Tours from Santiago to Buenos Aires Tours from Santiago to Santiago Tours from Sydney to Sydney Tours from Vancouver to Vancouver

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations