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Panama Tours & Cruises Starting In December 2026, 2027 and 2028

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6 Days
171 Days
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62 Trips (700 Trip Departures)
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise
 (5)

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama, Costa Rica
Viking $499 Air Deal
Inside
-
Oceanview
-
Balcony
$6,599
Suite
$11,999
From
US$6,599
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 13 December 2026
Visit: USA, Cayman Islands, Jamaica, Curacao (+7 more), Bonaire, Aruba, Colombia, Panama, Costa Rica, Honduras, Belize
Inside
$2,735
Oceanview
$3,015
Balcony
$3,605
Suite
$13,101
From
US$2,735
Per Person
View Trip
37 Day Caribbean To Cape Horn with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$10,849
Oceanview
$11,099
Balcony
-
Suite
-
From
US$10,849
Save 10,849
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$6,040
Suite
$10,060
From
US$6,040
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (9)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Crown Princess
Departure: 03 December 2026
Visit: USA, Mexico, Costa Rica, Panama, Curacao
Princess Standard
Inside
$999
Oceanview
$1,489
Balcony
$1,829
Suite
$2,399
From
US$999
Per Person
View Trip
19 Day Panama Canal Cruise: Colombia, Costa Rica & Mexico with Azamara Cruises
Cruise
 (5)

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 18 December 2026
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Azamara Always Included
Inside
$4,229
Oceanview
$4,859
Balcony
$5,299
Suite
$8,219
From
US$4,229
Per Person
View Trip
171 Day Viking World Voyage III with Viking Cruises
Cruise
 (5)

171 Days (170 Nights) Fort Lauderdale to Stockholm
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama (+38 more), Costa Rica, French Polynesia, Cook Islands, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Kenya, Tanzania, Madagascar, Mozambique, South Africa, Namibia, Angola, Nigeria, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England, Ireland, Wales, Northern Ireland, Scotland, Norway, Denmark, Germany, Poland, Estonia, Sweden
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$83,995
Suite
$149,995
From
US$83,995
Save 3,000
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 28 December 2026
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,842
Oceanview
$1,939
Balcony
$2,299
Suite
$2,709
From
US$1,842
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 20 December 2026
Visit: Colombia, Aruba, Bonaire, Panama
Exclusive Savings
Inside
$1,680
Oceanview
$1,691
Balcony
$2,385
Suite
$2,303
From
US$1,680
Save 840
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 12 December 2026
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,349
Oceanview
$1,489
Balcony
$1,497
Suite
$1,819
From
US$1,349
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,738
Save 374
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$3,516
Save 952
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operated By: Intrepid Travel
Departures: Jul 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$8,128
Save 2,199
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Dec 2026 to Dec 2026
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,049
Oceanview
$1,194
Balcony
$1,479
Suite
$2,239
From
US$1,049
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$12,800
Balcony
$13,800
Suite
$23,100
From
US$12,800
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 23 December 2027
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,429
Oceanview
$1,739
Balcony
$1,999
Suite
$2,799
From
US$1,429
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Visit: Panama
Exclusive Savings
From
US$809
Save 100
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 05 December 2026
Visit: USA, Cayman Islands, Jamaica, Colombia, Panama, Costa Rica, Bahamas
Princess Standard
Inside
$860
Oceanview
$949
Balcony
$1,389
Suite
$1,719
From
US$860
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,124
Save 125
Per Person
View Trip
30 Day Holiday Harbors & Hollywood with Oceania Cruises
Cruise

30 Days (29 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 December 2027
Visit: USA, Aruba, Curacao, Bonaire (+11 more), Grenada, Barbados, Saint Lucia, Guadeloupe, Virgin Islands, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,249
Suite
$19,899
From
US$14,249
Save 14,249
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visit: USA, Mexico, Guatemala, Belize (+5 more), Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,849
Suite
$13,799
From
US$12,849
Save 12,849
Per Person
View Trip
26 Day Ultimate Island Holiday with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 19 December 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Barthelemy (+14 more), Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Saint Lucia, Barbados, Grenada, Aruba, Bonaire, Curacao, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,949
Suite
$20,599
From
US$19,949
Save 19,949
Per Person
View Trip
17 Day Panama Canal & Pacific Gems with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 December 2026
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,599
Suite
$17,249
From
US$16,599
Save 16,599
Per Person
View Trip
11 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 11 December 2027
Visit: USA, Colombia, Panama, Costa Rica, Jamaica, Bahamas
Inside
$1,439
Oceanview
$1,739
Balcony
$2,689
Suite
$2,889
From
US$1,439
Per Person
View Trip
12 Day Central America From Miami To Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Jewel, Norwegian Sun
Departures: Feb 2027 to Dec 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Belize, Mexico
Inside
$1,509
Oceanview
$1,849
Balcony
$2,939
Suite
$3,329
From
US$1,509
Per Person
View Trip
17 Day Halcyon Holidays with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 19 December 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$11,899
From
US$8,299
Save 8,299
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$14,649
From
US$14,649
Save 14,649
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operated By: Globus
Departures: Jun 2026 to Mar 2027
Trip Styles: Short Break, Scenic
Visit: Panama
From
US$1,759
Per Person
View Trip
62 Day Total Central America: Two Months of Wild with G Adventures
New ReleaseTour

62 Days Mexico City to Panama City
Operated By: G Adventures
Departures: Jun 2026 to Jun 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Guatemala, Mexico, Nicaragua, Panama (+4 more), Belize, Honduras, Costa Rica, El Salvador
From
US$6,199
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
From
US$2,099
Per Person
View Trip
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