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Multi-Day Tours From Santiago

Choose from 26 unique multi-day guided tours starting in Santiago, and travelling to Arequipa, Buenos Aires, Cusco, El Calafate, Lima and more. October is the most popular month to join a tour from Santiago and you can select from 1,055 departures available from twelve leading tour operators.
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4 Days
26 Days
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26 Tours (1,055 Tour Departures)
20 Day Highlights of South America with Travelmarvel
Tour
 (4)

20 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Jul 2023 to Sep 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Argentina, Brazil, Peru
Earlybird SavingEarlybird Saving + Early Payment Discount
Save 971
From 9,825
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18 Day Best of South America with APT
Tour
 (1)

18 Days Santiago to Cusco
Operated By: APT
Departures: Jul 2023 to Sep 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Argentina, Brazil, Peru
Earlybird OfferEarlybird Saving
Save 1,519
From 14,076
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13 Day Patagonia: Journey to the End of the World with Globus
Tour

13 Days Santiago to Buenos Aires
Operated By: Globus
Departures: Jan 2023 to Dec 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Argentina, Chile
Exclusive Savings
Save 177
From 8,798
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15 Day Premium Chile, Argentina & Brazil with Intrepid Travel
Tour

15 Days Santiago to Rio de Janeiro
Operated By: Intrepid Travel
Departures: Jan 2023 to Dec 2023
Trip Styles: Fully Guided, Adventure, Small Group
Countries Visited: Chile, Argentina, Brazil
Exclusive Savings
Save 259
From 11,417
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5 Day Easter Island Extension with Exodus Travels
Tour

5 Days Santiago to Santiago
Operated By: Exodus Travels
Departures: Dec 2022 to Dec 2023
Trip Styles: Fully Guided, Adventure, Small Group, Short Break
Countries Visited: Chile, Easter Island
Exclusive Savings
Save 52
From 2,331
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21 Day South America Inca Journey with APT
Tour

21 Days Santiago to Arequipa
Operated By: APT
Departures: Jul 2023 to Oct 2023
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing, Andean Explorer
Countries Visited: Chile, Argentina, Brazil, Peru
Earlybird Offer
Save 1,175
From 19,720
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12 Day The Best of Brazil and Argentina with Santiago with Cosmos
Tour

12 Days Santiago to Buenos Aires
Operated By: Cosmos
Departures: Jan 2023 to Nov 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Brazil, Argentina
Exclusive Savings
Save 64
From 3,844
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4 Day Independent Santiago City Stay with Globus
New ReleaseTour

4 Days Santiago to Santiago
Operated By: Globus
Departures: Feb 2023 to Dec 2023
Trip Styles: Locally Guided, Short Break, Scenic / Sightseeing
Countries Visited: Chile
Exclusive Savings
Save 25
From 1,224
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26 Day Ultimate South America with A Santiago Stopover, Arequipa & The Colca Canyon with Cosmos
Tour

26 Days Santiago to Lima
Operated By: Cosmos
Departures: Jan 2023 to Nov 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Brazil, Argentina, Peru (+1 more), Ecuador
Exclusive Savings
Save 137
From 8,566
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23 Day Ultimate Chile & Argentina with Bunnik Tours
TourFlights Included

23 Days Santiago to Santiago
Operated By: Bunnik Tours
Departures: Sep 2023 to Mar 2024
Trip Styles: Fully Guided, Coach, Small Group, Scenic / Sightseeing
Countries Visited: Chile, Argentina
Exclusive Savings
Save 338
From 15,095
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10 Day Trek Patagonia with Intrepid Travel
Tour

10 Days Santiago to Buenos Aires
Operated By: Intrepid Travel
Departures: Dec 2022 to Dec 2023
Trip Styles: Fully Guided, Adventure, Small Group, Walking & Hiking
Countries Visited: Chile, Argentina
Limited Time Sale
Save 1,550
From 5,900
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4 Day Santiago Short Break with Intrepid Travel
Tour

4 Days Santiago to Santiago
Operated By: Intrepid Travel
Departures: Dec 2022 to Dec 2023
Trip Styles: Fully Guided, Adventure, Small Group, Short Break
Countries Visited: Chile
Exclusive Savings
Save 21
From 985
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22 Day Ultimate South America with Santiago Stopover with Cosmos
Tour

22 Days Santiago to Lima
Operated By: Cosmos
Departures: Jan 2023 to Nov 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Brazil, Argentina, Peru
Exclusive Savings
Save 111
From 7,368
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10 Day Highlights of Chile & Argentina with G Adventures
Tour

10 Days Santiago to Buenos Aires
Operated By: G Adventures
Departures: Jan 2023 to Dec 2024
Trip Styles: Fully Guided, Adventure, Small Group
Countries Visited: Argentina, Chile
Exclusive Savings
Save 62
From 2,694
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9 Day Patagonian Adventure with Scenic
Tour

9 Days Santiago to El Calafate
Operated By: Scenic
Departures: Nov 2023 to Feb 2024
Trip Styles: Fully Guided, Small Group, Scenic / Sightseeing
Countries Visited: Chile, Argentina
Exclusive Savings
Save 298
From 14,303
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12 Day Classic South America with Luxury Gold
Tour

12 Days Santiago to Rio de Janeiro
Operated By: Luxury Gold
Departures: Feb 2023 to Nov 2023
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Argentina, Brazil
Exclusive Savings
Save 255
From 13,345
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11 Day Patagonia with Tauck
Tour

11 Days Santiago to Buenos Aires
Operated By: Tauck
Departures: Feb 2023 to Dec 2023
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Argentina
Exclusive Savings
Save 250
From 11,554
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9 Day Premium Chile & Argentina with Intrepid Travel
Tour

9 Days Santiago to Buenos Aires
Operated By: Intrepid Travel
Departures: Jan 2023 to Dec 2024
Trip Styles: Fully Guided, Adventure, Small Group
Countries Visited: Chile, Argentina
Limited Time Sale
Save 372
From 5,356
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11 Day Best of Chile from Atacama to Patagonia with Insight Vacations
Tour

11 Days Santiago to Santiago
Operated By: Insight Vacations
Departures: Apr 2023 to Oct 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile
Earlybird Saving
Save 1,086
From 10,154
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18 Day Andes, Iguassu & Beyond with G Adventures
Tour
 (1)

18 Days Santiago to Rio de Janeiro
Operated By: G Adventures
Departures: Jan 2023 to Dec 2024
Trip Styles: Fully Guided, Adventure, Small Group
Countries Visited: Argentina, Chile, Brazil
Exclusive Savings
Save 113
From 5,242
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8 Day Wild Landscapes of Atacama with Scenic
Tour

8 Days Santiago to Santiago
Operated By: Scenic
Departures: Nov 2023 to Mar 2024
Trip Styles: Fully Guided, Small Group, Scenic / Sightseeing
Countries Visited: Chile
Exclusive Savings
Save 206
From 8,815
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13 Day Discover Chile with Exodus Travels
Tour

13 Days Santiago to Santiago
Operated By: Exodus Travels
Departures: Feb 2023 to Dec 2023
Trip Styles: Fully Guided, Small Group, Scenic / Sightseeing
Countries Visited: Chile
Exclusive Savings
Save 177
From 8,280
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18 Day Patagonia: Journey to the End of the World with Easter Island with Globus
Tour

18 Days Santiago to Buenos Aires
Operated By: Globus
Departures: Jan 2023 to Nov 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Argentina, Chile
Exclusive Savings
Save 215
From 11,353
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22 Day South America Inca Journey with APT
Tour

22 Days Santiago to Arequipa
Operated By: APT
Departures: Jun 2024 to Aug 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing, Andean Explorer
Countries Visited: Chile, Argentina, Brazil, Peru
Earlybird Saving
Save 1,579
From 20,316
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11 Day Best of Chile from Atacama to Patagonia (Small Group) with Insight Vacations
Tour

11 Days Santiago to Santiago
Operated By: Insight Vacations
Departure: 20 April 2024
Trip Styles: Fully Guided, Coach, Small Group, Scenic / Sightseeing
Countries Visited: Chile
Exclusive Savings
Save 219
From 11,999
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18 Day Spirit of South America with Santiago with Globus
Tour

18 Days Santiago to Lima
Operated By: Globus
Departures: Mar 2023 to Nov 2024
Trip Styles: Fully Guided, Coach, Scenic / Sightseeing
Countries Visited: Chile, Brazil, Argentina, Peru
Exclusive Savings
Save 159
From 9,264
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Results: 26 results

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South America Tours

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Travel Styles

18-30's Tours Active Adventures Coach Tours Short Breaks Small Group Tours Walking & Hiking Tours

Departure Months

December 2022 January 2023 February 2023 March 2023 April 2023 May 2023 June 2023 July 2023 August 2023 September 2023 October 2023 November 2023 December 2023 January 2024 February 2024 March 2024 April 2024 May 2024 June 2024 July 2024 August 2024 September 2024 October 2024 November 2024 December 2024

Cities

Santiago

Routes

Santiago to Buenos Aires Santiago to Santiago

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