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Tours From Santiago

Choose from 18 unique multi-day guided tours starting in Santiago, and traveling to Buenos Aires, Cusco, El Calafate, Lima, Rio de Janeiro and more. October is the most popular month to join a tour from Santiago and you can select from 837 departures available from eleven leading tour operators.
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18 Tours (837 Tour Departures)
20 Day Highlights of South America with Travelmarvel
Tour
 (4)

20 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru
Exclusive Deal
Save
300
From
9,695
per person
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18 Day Patagonia: Journey to the End of the World with Easter Island with Globus
Tour

18 Days Santiago to Buenos Aires
Operated By: Globus
Departures: Oct 2025 to Dec 2027
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Easter Island, Argentina
Exclusive Savings
Save
323
From
11,039
per person
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9 Day Premium Chile & Argentina with Intrepid Travel
Tour

9 Days Santiago to Buenos Aires
Operated By: Intrepid Travel
Departures: Aug 2025 to Dec 2027
Trip Styles: Adventure, Small Group
Countries Visited: Chile, Argentina
Exclusive Deal
Save
1,725
From
3,769
per person
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4 Day Santiago Short Break with Intrepid Travel
Tour

4 Days Santiago to Santiago
Operated By: Intrepid Travel
Departures: Aug 2025 to Dec 2026
Trip Styles: Adventure, Small Group, Short Break
Countries Visited: Chile
From
803
per person
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14 Day Chile & Argentina: Capital Cities & Hiking Patagonia with G Adventures
New ReleaseTour

14 Days Santiago to Buenos Aires
Operated By: G Adventures
Departures: Oct 2025 to Mar 2027
Trip Styles: Adventure, Small Group, Walking & Hiking
Countries Visited: Chile, Argentina
Exclusive Savings
Save
224
From
9,799
per person
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11 Day Best of Chile from Atacama to Patagonia with Insight Vacations
Tour

11 Days Santiago to Santiago
Operated By: Insight Vacations
Departures: Nov 2025 to Dec 2025
Trip Styles: Coach, Scenic
Countries Visited: Chile
Sign Up Savings
Save
324
From
9,451
per person
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12 Day Classic South America with Luxury Gold
Tour

12 Days Santiago to Rio de Janeiro
Operated By: Luxury Gold
Departures: Mar 2026 to Nov 2026
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Savings
Save
202
From
10,781
per person
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12 Day Chile, Argentina and Brazil Discovery with APT
Tour

12 Days Santiago to Rio de Janeiro
Operated By: APT
Departures: Mar 2026 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Deal
Save
400
From
8,845
per person
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4 Day Independent Santiago City Stay with Globus
New ReleaseTour

4 Days Santiago to Santiago
Operated By: Globus
Departures: Aug 2025 to Mar 2027
Trip Styles: Short Break, Scenic
Countries Visited: Chile
World of Wonder Sale
Save
150
From
989
per person
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9 Day Premium Patagonia with Intrepid Travel
Tour

9 Days Santiago to Ushuaia
Operated By: Intrepid Travel
Departures: Nov 2025 to Dec 2027
Trip Styles: Adventure, Small Group, Walking & Hiking
Countries Visited: Chile, Argentina
Exclusive Savings
Save
210
From
8,580
per person
View Trip
19 Day Best of South America with APT
Tour

19 Days Santiago to Cusco
Operated By: APT
Departures: Mar 2026 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru
Exclusive Deal
Save
700
From
13,395
per person
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13 Day Highlights of Chile - Atacama to Paine with Explore Worldwide
Tour

13 Days Santiago to Santiago
Operated By: Explore Worldwide
Departures: Nov 2025 to Dec 2026
Trip Styles: Adventure, Small Group
Countries Visited: Chile
Mutiple Deals Available
Save
852
From
5,486
per person
View Trip
11 Day Patagonia with Tauck
Tour

11 Days Santiago to Buenos Aires
Operated By: Tauck
Departures: Mar 2026 to Dec 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina
From
9,990
per person
View Trip
11 Day South American Treasures with Travelmarvel
New ReleaseTour

11 Days Santiago to Rio de Janeiro
Operated By: Travelmarvel
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Deal
Save
100
From
5,395
per person
View Trip
9 Day Patagonian Adventure with Scenic
Tour

9 Days Santiago to El Calafate
Operated By: Scenic
Departures: Feb 2026 to Feb 2027
Trip Styles: Small Group, Scenic
Countries Visited: Chile, Argentina
Exclusive Deal
From
16,055
per person
View Trip
13 Day Patagonia: Journey to the End of the World with Globus
Tour

13 Days Santiago to Buenos Aires
Operated By: Globus
Departures: Oct 2025 to Dec 2027
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Argentina
Mutiple Deals Available
Save
732
From
8,262
per person
View Trip
15 Day Premium Chile, Argentina & Brazil with Intrepid Travel
Tour

15 Days Santiago to Rio de Janeiro
Operated By: Intrepid Travel
Departures: Aug 2025 to Dec 2027
Trip Styles: Adventure, Small Group
Countries Visited: Chile, Argentina, Brazil
Exclusive Deal
Save
1,696
From
8,134
per person
View Trip
9 Day Essential South America with Collette
New ReleaseTour

9 Days Santiago to Buenos Aires
Operated By: Collette
Departures: Sep 2025 to May 2027
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Argentina
Exclusive Savings
Save
88
From
4,515
per person
View Trip
Results: 18 results

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South America Tours

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Travel Styles

18-30's Tours Adventure Tours Coach Tours Luxury Tours Short Break Tours Small Group Tours Walking & Hiking Tours Wildlife Tours

Departure Months

August 2025 September 2025 October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026 January 2027 February 2027 March 2027 April 2027 May 2027 June 2027 July 2027 August 2027 September 2027 October 2027 November 2027 December 2027

Cities

Santiago

Routes

Santiago to Buenos Aires

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