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Tours from Santiago

Choose from 25 unique multi-day guided tours starting in Santiago, and traveling to Buenos Aires, Cusco, El Calafate, La Paz, Lima and more. October and November are the most popular months to join a tour from Santiago and you can select from 551 departures available from twelve leading tour operators.
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25 Tours (551 Departures)
25 Tours (551 Departures)
Departures
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Duration
4 Days
23 Days
Countries Visited
End City
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Price
$1,200pp
$18,805pp
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20 Day Highlights of South America with Travelmarvel
Tour
 (5)

20 Days Santiago to Lima or Rio de Janeiro to Lima
Operator: Travelmarvel
Departures: Apr 2027 to Oct 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina, Brazil, Peru
From (Per Person)
US$10,195
Per Person
View Trip
12 Day South American Adventure: Chile, Argentina & Brazil with Abercrombie & Kent
Tour

12 Days Santiago to Rio de Janeiro
Operator: Abercrombie & Kent
Departures: Jan 2027 to Nov 2027
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina, Brazil
Exclusive Savings
From (Per Person)
US$15,045
Save 750
Per Person
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9 Day Premium Patagonia with Intrepid Travel
Tour

9 Days Santiago to Ushuaia
Operator: Intrepid
Departures: Nov 2026 to Dec 2028
Trip Styles: Adventure, Small Group, Walking & Hiking
Visits: Chile, Argentina
From (Per Person)
US$9,480
Per Person
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13 Day Highlights of Chile - Atacama to Paine with Explore Worldwide
Tour

13 Days Santiago to Santiago
Operator: Explore
Departures: Oct 2026 to Dec 2027
Trip Style: Adventure
Visits: Chile
Exclusive Savings
From (Per Person)
US$7,030
Save 210
Per Person
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18 Day Patagonia: Journey to the End of the World with Easter Island with Globus
Tour

18 Days Santiago to Buenos Aires
Operator: Globus
Departures: Oct 2026 to Nov 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Easter Island, Argentina
Exclusive Savings
From (Per Person)
US$11,822
Save 250
Per Person
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18 Day Patagonia: Journey to the End of the World with Iguassu Falls & Rio with Globus
Tour

18 Days Santiago to Rio de Janeiro
Operator: Globus
Departures: Jan 2027 to Dec 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina, Brazil
Exclusive Savings
From (Per Person)
US$11,214
Save 250
Per Person
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11 Day Patagonia with Tauck
Tour

11 Days Santiago to Buenos Aires
Operator: Tauck
Departures: Mar 2027 to Dec 2027
Trip Styles: Coach, Scenic
Visits: Chile, Argentina
From (Per Person)
US$10,490
Per Person
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4 Day Independent Santiago City Stay with Globus
New ReleaseTour

4 Days Santiago to Santiago
Operator: Globus
Departures: Sep 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Chile
From (Per Person)
US$1,209
Per Person
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12 Day Heart of Patagonia with Insight Vacations
New ReleaseTour

12 Days Santiago to Buenos Aires
Operator: Insight Vacations
Departures: Oct 2026 to Nov 2026
Trip Styles: Coach, Scenic
Visits: Chile, Argentina
Exclusive Savings
From (Per Person)
US$7,694
Save 801
Per Person
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16 Day Chile & Northern Patagonia in Depth with the Atacama with Globus
New ReleaseTour

16 Days Santiago to Buenos Aires
Operator: Globus
Departures: Apr 2027 to Nov 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina
Exclusive Savings
From (Per Person)
US$9,354
Save 250
Per Person
View Trip
19 Day Best of South America with APT
Tour

19 Days Santiago to Cusco or Rio de Janeiro to Cusco
Operator: APT
Departures: Apr 2027 to Nov 2028
Trip Styles: Small Group, Scenic
Visits: Chile, Argentina, Brazil, Peru
From (Per Person)
US$15,895
Per Person
View Trip
21 Day Chile & Northern Patagonia in Depth with the Atacama, Iguassu Falls & Rio with Globus
New ReleaseTour

21 Days Santiago to Rio de Janeiro
Operator: Globus
Departures: Apr 2027 to Nov 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina, Brazil
Exclusive Savings
From (Per Person)
US$11,349
Save 250
Per Person
View Trip
23 Day Patagonia: Journey to the End of the World with Easter Island, Iguassu Falls & Rio with Globus
Tour

23 Days Santiago to Rio de Janeiro
Operator: Globus
Departures: Jan 2027 to Nov 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Easter Island, Argentina, Brazil
Exclusive Savings
From (Per Person)
US$14,374
Save 250
Per Person
View Trip
17 Day Chile & Northern Patagonia in Depth with Iguassu Falls & Rio with Globus
New ReleaseTour

17 Days Santiago to Rio de Janeiro
Operator: Globus
Departures: Apr 2027 to Nov 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina, Brazil
Exclusive Savings
From (Per Person)
US$7,949
Save 250
Per Person
View Trip
14 Day Chile & Argentina: Capital Cities & Hiking Patagonia with G Adventures
New ReleaseTour

14 Days Santiago to Buenos Aires
Operator: G Adventures
Departures: Nov 2026 to Mar 2028
Trip Styles: Adventure, Small Group, Walking & Hiking
Visits: Chile, Argentina
Exclusive Savings
From (Per Person)
US$10,349
Save 1,150
Per Person
View Trip
12 Day Chile & Northern Patagonia in Depth with Globus
New ReleaseTour

12 Days Santiago to Buenos Aires
Operator: Globus
Departures: Apr 2027 to Nov 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina
Exclusive Savings
From (Per Person)
US$5,946
Save 250
Per Person
View Trip
15 Day Premium Chile, Argentina & Brazil with Intrepid Travel
Tour

15 Days Santiago to Rio de Janeiro
Operator: Intrepid
Departures: Sep 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Chile, Argentina, Brazil
Exclusive Savings
From (Per Person)
US$10,191
Save 1,799
Per Person
View Trip
9 Day Patagonian Adventure with Scenic
Tour

9 Days Santiago to El Calafate
Operator: Scenic
Departures: Nov 2026 to Feb 2028
Trip Styles: Small Group, Scenic
Visits: Chile, Argentina
From (Per Person)
US$17,665
Per Person
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12 Day Classic South America with Luxury Gold
Tour

12 Days Santiago to Rio de Janeiro
Operator: Luxury Gold
Departures: Sep 2026 to Nov 2027
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina, Brazil
From (Per Person)
US$10,983
Per Person
View Trip
9 Day Essential South America with Collette
New ReleaseTour

9 Days Santiago to Buenos Aires
Operator: Collette
Departures: Sep 2026 to Jun 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina
Exclusive Savings
From (Per Person)
US$4,599
Save 300
Per Person
View Trip
8 Day Easter Island & the Tapati Festival with Abercrombie & Kent
Tour

8 Days Santiago to Santiago
Operator: Abercrombie & Kent
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Easter Island
From (Per Person)
US$14,995
Per Person
View Trip
12 Day Chile, Argentina and Brazil Discovery with APT
Tour

12 Days Santiago to Rio de Janeiro or Rio de Janeiro to Santiago
Operator: APT
Departures: Apr 2027 to Nov 2028
Trip Styles: Small Group, Scenic
Visits: Chile, Argentina, Brazil
From (Per Person)
US$10,595
Per Person
View Trip
9 Day Chile & Bolivia: Atacama to Uyuni Salt Flats with Abercrombie & Kent
Tour

9 Days Santiago to La Paz
Operator: Abercrombie & Kent
Departures: Apr 2027 to Nov 2027
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Bolivia
Exclusive Savings
From (Per Person)
US$12,390
Save 680
Per Person
View Trip
9 Day Premium Chile & Argentina with Intrepid Travel
Tour

9 Days Santiago to Buenos Aires
Operator: Intrepid
Departures: Sep 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Chile, Argentina
Exclusive Savings
From (Per Person)
US$5,471
Save 1,824
Per Person
View Trip
13 Day Patagonia: Journey to the End of the World with Globus
Tour

13 Days Santiago to Buenos Aires
Operator: Globus
Departures: Nov 2026 to Dec 2028
Trip Styles: Coach, Small Group, Scenic
Visits: Chile, Argentina
Exclusive Savings
From (Per Person)
US$8,994
Save 250
Per Person
View Trip
Results: 25 results

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South America Tours

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Travel Styles

18-30's Tours Adventure Tours Coach Tours Luxury Tours Short Break Tours Small Group Tours Walking & Hiking Tours Wildlife Tours

Trip Lengths

10 Day 2 Week

Departure Months

September October November December January February March April May June July August

Cities

Santiago

Routes

Rio de Janeiro to Santiago Santiago to Buenos Aires Santiago to Rio de Janeiro Santiago to Santiago
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