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Tours From Santiago

Choose from 18 unique multi-day guided tours starting in Santiago, and traveling to Buenos Aires, Cusco, El Calafate, Lima, Rio de Janeiro and more. March and October are the most popular months to join a tour from Santiago and you can select from 798 departures available from eleven leading tour operators.
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18 Tours (798 Tour Departures)
20 Day Highlights of South America with Travelmarvel
Tour
 (4)

20 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru
Exclusive Deal
Save (per person) 300
From (per person) 9,695
View Trip
9 Day Patagonian Adventure with Scenic
Tour

9 Days Santiago to El Calafate
Operated By: Scenic
Departures: Feb 2026 to Feb 2027
Trip Styles: Small Group, Scenic
Countries Visited: Chile, Argentina
From (per person) 16,055
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4 Day Independent Santiago City Stay with Globus
New ReleaseTour

4 Days Santiago to Santiago
Operated By: Globus
Departures: Jul 2025 to Mar 2026
Trip Styles: Short Break, Scenic
Countries Visited: Chile
From (per person) 1,139
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19 Day Best of South America with APT
Tour

19 Days Santiago to Cusco
Operated By: APT
Departures: Sep 2025 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru
Exclusive Deal
Save (per person) 700
From (per person) 12,495
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12 Day Chile, Argentina and Brazil Discovery with APT
Tour

12 Days Santiago to Rio de Janeiro
Operated By: APT
Departures: Mar 2026 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Deal
Save (per person) 400
From (per person) 8,845
View Trip
15 Day Premium Chile, Argentina & Brazil with Intrepid Travel
Tour

15 Days Santiago to Rio de Janeiro
Operated By: Intrepid Travel
Departures: Jul 2025 to Dec 2027
Trip Styles: Adventure, Small Group
Countries Visited: Chile, Argentina, Brazil
Exclusive Deal
Save (per person) 1,631
From (per person) 8,134
View Trip
9 Day Premium Chile & Argentina with Intrepid Travel
Tour

9 Days Santiago to Buenos Aires
Operated By: Intrepid Travel
Departures: Jul 2025 to Dec 2027
Trip Styles: Adventure, Small Group
Countries Visited: Chile, Argentina
Exclusive Deal
Save (per person) 1,456
From (per person) 4,039
View Trip
11 Day South American Treasures with Travelmarvel
New ReleaseTour

11 Days Santiago to Rio de Janeiro
Operated By: Travelmarvel
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Deal
Save (per person) 100
From (per person) 5,395
View Trip
11 Day Best of Chile from Atacama to Patagonia with Insight Vacations
Tour

11 Days Santiago to Santiago
Operated By: Insight Vacations
Departures: Oct 2025 to Dec 2025
Trip Styles: Coach, Scenic
Countries Visited: Chile
Sign Up Savings
Save (per person) 324
From (per person) 9,451
View Trip
13 Day Patagonia: Journey to the End of the World with Globus
Tour

13 Days Santiago to Buenos Aires
Operated By: Globus
Departures: Oct 2025 to Dec 2026
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Argentina
Mutiple Deals Available
Save (per person) 251
From (per person) 8,345
View Trip
9 Day Essential South America with Collette
New ReleaseTour

9 Days Santiago to Buenos Aires
Operated By: Collette
Departures: Sep 2025 to Apr 2026
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Argentina
Exclusive Savings
Save (per person) 86
From (per person) 4,613
View Trip
12 Day Classic South America with Luxury Gold
Tour

12 Days Santiago to Rio de Janeiro
Operated By: Luxury Gold
Departures: Apr 2026 to Nov 2026
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Savings
Save (per person) 202
From (per person) 10,781
View Trip
13 Day Highlights of Chile - Atacama to Paine with Explore!
Tour

13 Days Santiago to Santiago
Operated By: Explore!
Departures: Oct 2025 to Dec 2026
Trip Styles: Adventure, Small Group
Countries Visited: Chile
Sign Up Savings
Save (per person) 852
From (per person) 5,486
View Trip
11 Day Patagonia with Tauck
Tour

11 Days Santiago to Buenos Aires
Operated By: Tauck
Departures: Feb 2026 to Dec 2026
Trip Styles: Coach, Scenic
Countries Visited: Chile, Argentina
From (per person) 9,990
View Trip
4 Day Santiago Short Break with Intrepid Travel
Tour

4 Days Santiago to Santiago
Operated By: Intrepid Travel
Departures: Jul 2025 to Dec 2026
Trip Styles: Adventure, Small Group, Short Break
Countries Visited: Chile
From (per person) 803
View Trip
14 Day Chile & Argentina: Capital Cities & Hiking Patagonia with G Adventures
New ReleaseTour

14 Days Santiago to Buenos Aires
Operated By: G Adventures
Departures: Oct 2025 to Mar 2027
Trip Styles: Adventure, Small Group, Walking & Hiking
Countries Visited: Chile, Argentina
Exclusive Deal
Save (per person) 1,180
From (per person) 8,819
View Trip
9 Day Premium Patagonia with Intrepid Travel
Tour

9 Days Santiago to Ushuaia
Operated By: Intrepid Travel
Departures: Nov 2025 to Dec 2027
Trip Styles: Adventure, Small Group, Walking & Hiking
Countries Visited: Chile, Argentina
Exclusive Savings
Save (per person) 196
From (per person) 8,580
View Trip
18 Day Patagonia: Journey to the End of the World with Easter Island with Globus
Tour

18 Days Santiago to Buenos Aires
Operated By: Globus
Departures: Oct 2025 to Dec 2026
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Chile, Easter Island, Argentina
Exclusive Savings
Save (per person) 299
From (per person) 11,039
View Trip
Results: 18 results

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South America Tours

All South America Tours Amazon Tours Argentina Tours Brazil Tours Chile Tours Colombia Tours Ecuador Tours Galapagos Tours Patagonia Tours Peru Tours

Travel Styles

18-30's Tours Adventure Tours Coach Tours Luxury Tours Short Break Tours Small Group Tours Walking & Hiking Tours Wildlife Tours

Departure Months

July 2025 August 2025 September 2025 October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026 January 2027 February 2027 March 2027 April 2027 May 2027 June 2027 July 2027 August 2027 September 2027 October 2027 November 2027 December 2027

Cities

Santiago

Routes

Santiago to Buenos Aires

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