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All Panama Tours & Cruises

Explore the colors and natural beauty of Panama - a land between the seas. Travel via dugout canoe to meet the indigenous Emberá people, visit gorgeous islands, snorkel the Caribbean and cruise through the world-famous Panama Canal. Choose from 1,237 cruises, small group tours and adventures to Panama travelling with the world's leading tour operators.
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398 Trips (1,237 Departures)
398 Trips (1,237 Departures)
Departures
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Duration
6 Days
181 Days
Types
Budget
Start & End Cities
Operators
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Price
$900pp
$245,249pp
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9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Aug 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,092
Save 161
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Oct 2026 to Feb 2028
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,322
Save 177
Per Person
View Trip
6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Aug 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,715
Save 105
Per Person
View Trip
8 Day Coastal Adventures: Panama & Costa Rica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Panama City to San Jose
Operator: Emerald Cruises
Ships: Emerald Azzurra
Departures: Jan 2028 to Jan 2029
Visits: Panama, Costa Rica
Exclusive Savings
Oceanview
$8,150
Suite
$10,301
From (Per Person)
A$8,150
Save 2,647
Per Person
View Trip
13 Day Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Operator: Emerald Cruises
Ships: Emerald Azzurra
Departures: Feb 2028 to Feb 2029
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$14,745
Suite
$17,621
From (Per Person)
A$14,745
Save 4,233
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Operator: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$9,787
Suite
$14,938
From (Per Person)
A$9,787
Save 273
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ship: Le Bougainville
Departure: 23 February 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$13,020
Suite
$21,935
From (Per Person)
A$13,020
Save 360
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$10,440
Suite
$17,366
From (Per Person)
A$10,440
Save 1,140
Per Person
View Trip
13 Day Costa Rica, Panama from the Atlantic to the Pacific via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Operator: Emerald Cruises
Ship: Emerald Azzurra
Departure: 31 January 2029
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$14,645
Suite
$17,521
From (Per Person)
A$14,645
Save 4,220
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$7,750
Suite
$12,959
From (Per Person)
A$7,750
Save 258
Per Person
View Trip
8 Day Coastal Adventures: Costa Rica & Panama with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) San Jose to Panama City
Operator: Emerald Cruises
Ships: Emerald Azzurra
Departures: Feb 2028 to Feb 2029
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$8,150
Suite
$10,301
From (Per Person)
A$8,150
Save 2,646
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Colon
Operator: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Mar 2027
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$7,556
Suite
$12,610
From (Per Person)
A$7,556
Save 217
Per Person
View Trip
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys with Ponant
Cruise
 (2)

8 Days (7 Nights) Puntarenas to Colon
Operator: Ponant
Ship: Le Laperouse
Departure: 19 February 2027
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$11,077
Suite
$18,508
From (Per Person)
A$11,077
Save 313
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$10,440
Suite
$17,366
From (Per Person)
A$10,440
Save 460
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$3,086
Save 72
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Aug 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,003
Save 917
Per Person
View Trip
11 Day From Panama’s Wild Beauty to Peruvian Shores with Ponant
Cruise

11 Days (10 Nights) Colon to Lima
Operator: Ponant
Ship: L'Austral
Departure: 20 October 2026
Visits: Panama, Peru
Exclusive Savings
Oceanview
$8,452
Balcony
$9,101
Suite
$16,939
From (Per Person)
A$8,452
Save 218
Per Person
View Trip
10 Day Panama and Costa Rica: Crossing the Canal with Aurora Expeditions
New ReleaseCruise

10 Days (9 Nights) Panama City to San Jose
Operator: Aurora Expeditions
Ship: Douglas Mawson
Departure: 04 October 2027
Visits: Panama, Costa Rica
Exclusive Savings
Oceanview
$17,815
Balcony
$18,805
Suite
$28,309
From (Per Person)
A$17,815
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Oct 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,812
Save 40
Per Person
View Trip
12 Day Costa Rica & the Panama Canal with Aurora Expeditions
New ReleaseCruise

12 Days (11 Nights) San Jose to Panama City
Operator: Aurora Expeditions
Ship: Sylvia Earle
Departure: 09 April 2027
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
-
Balcony
$24,448
Suite
$35,833
From (Per Person)
A$24,448
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visits: Bahamas, Colombia, Panama
Exclusive Savings
Balcony
$12,497
Suite
$12,742
From (Per Person)
A$12,497
Save 3,698
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 802
Per Person
View Trip
7 Day Callao (Lima) to Fuerte Amador with Crystal Cruises
Cruise

7 Days (6 Nights) Lima to Panama City
Operator: Crystal
Ship: Crystal Serenity
Departure: 05 December 2027
Visits: Peru, Ecuador, Panama
Exclusive Savings
Oceanview
$5,277
Balcony
$6,252
Suite
$6,155
From (Per Person)
A$5,277
Save 123
Per Person
View Trip
14 Day Cycle Nicaragua to the Panama Canal with Explore Worldwide
Tour

14 Days Granada to Panama City
Operator: Explore
Departures: Oct 2026 to Nov 2027
Trip Styles: Adventure, Cycling
Visits: Costa Rica, Panama, Nicaragua
Exclusive Savings
From (Per Person)
A$7,076
Save 574
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 24 January 2027
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$2,101
Oceanview
$2,113
Balcony
$3,057
Suite
$3,325
From (Per Person)
A$2,101
Save 1,155
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,391
Oceanview
$1,547
Balcony
$2,081
Suite
$2,474
From (Per Person)
A$1,391
Save 1,269
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Mar 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,580
Oceanview
$1,758
Balcony
$2,420
Suite
$2,790
From (Per Person)
A$1,580
Save 970
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,466
Oceanview
$1,623
Balcony
$2,197
Suite
$2,578
From (Per Person)
A$1,466
Save 1,173
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visits: USA, Colombia, Panama, Mexico
Exclusive Savings
Inside
$2,575
Oceanview
$2,961
Balcony
$3,832
Suite
$15,523
From (Per Person)
A$2,575
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) Cartagena to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Nov 2026 to Apr 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,388
Oceanview
$1,644
Balcony
$2,258
Suite
$2,672
From (Per Person)
A$1,388
Save 1,198
Per Person
View Trip
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