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All Panama Tours & Cruises

Explore the colors and natural beauty of Panama - a land between the seas. Travel via dugout canoe to meet the indigenous Emberá people, visit gorgeous islands, snorkel the Caribbean and cruise through the world-famous Panama Canal. Choose from 120 cruises, small gropup tours and adventures to Panama. Compare trips, read past passenger reviews and enjoy exclusive savings on every departure.

  120 Trips Found
9 Day Discover Panama with Collette
Tour  

9 Days Panama City to Playa Bonita
Operated By: Collette (Guided Tour)
Journey to Panama on this 9 day guided tour with Collette, beginning your journey in Panama City and travelling through to Playa Bonita.
Exclusive: July Offer
Departures: Sep 2020 to Apr 2021 (12 Departures)
Countries Visited: Panama
Save
$ 330
From
$ 2,269
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8 Day Best of Panama with G Adventures
Tour  

8 Days Panama City to Panama City
Operated By: G Adventures (Small Group Tour)
Journey to Panama on this 8 day small group tour with G Adventures, beginning and ending your journey in Panama City.
Departures: Oct 2020 to Dec 2020 (2 Departures)
Countries Visited: Panama
Save
$ 216
From
$ 912
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12 Day The Panama Canal & Costa Rica - Westbound with Tauck
Cruise  

12 Days Panama City to San Jose
Operated By: Tauck (Small Ship Cruise)
Embark on a 11 night small ship cruise with Tauck visiting Panama & Costa Rica, beginning your journey in Panama City and travelling through to San Jose.
Exclusive: 1 Night Free!
Departures: Jan 2021 to Jan 2021 (2 Departures)
Regions: Central America
Save
$ 228
From
$ 10,868
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8 Day Natural & Cultural History of Central America with Ponant
Cruise  

8 Days Puerto Calderda to Colon
Operated By: Ponant (Cruise)
Ship: Le Champlain
Embark on a 7 night cruise with Ponant visiting Costa Rica & Panama, beginning your journey in Puerto Calderda and travelling through to Colon.
Departs: 05 January 2021
Regions: Central America
 
From
$ 5,740
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8 Day Cycle Costa Rica & Panama with Intrepid
Tour  

8 Days San Jose to Panama City
Operated By: Intrepid (Small Group Adventure)
Discover Costa Rica & Panama on this 8 day small group adventure with Intrepid, beginning your journey in San Jose and travelling through to Panama City.
Departures: Oct 2020 to Dec 2020 (3 Departures)
Countries Visited: Costa Rica, Panama
Save
$ 88
From
$ 2,112
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16 Day Costa Rica & Panama Experience with Intrepid
New 2019  Tour  

16 Days San Jose to Panama City
Operated By: Intrepid (Small Group Adventure)
Discover Costa Rica & Panama on this new 16 day small group adventure with Intrepid, beginning your journey in San Jose and travelling through to Panama City....
Departures: Oct 2020 to Dec 2020 (3 Departures)
Countries Visited: Costa Rica, Panama
Save
$ 148
From
$ 3,427
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8 Day Cruising Costa Rica & Panama with Peregrine
Cruise  

8 Days Puntarenas to Panama City
Operated By: Peregrine (Adventure Cruise)
Embark on a 7 night adventure cruise with Peregrine visiting Costa Rica & Panama, beginning your journey in Puntarenas and travelling through to Panama City....
Departs: 23 January 2021
Regions: Central America
Save
$ 70
From
$ 3,425
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8 Day Tropical Rainforests & the Panama Canal - with National Geographic with Ponant
Cruise  

8 Days Colon to Puerto Calderda
Operated By: Ponant (Cruise)
Embark on a 7 night cruise with Ponant visiting Panama & Costa Rica, beginning your journey in Colon and travelling through to Puerto Calderda.
Departs: 04 January 2021
Regions: Central America
 
From
$ 5,580
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8 Day National Parks and Panama Canal with Ponant
Cruise  

8 Days Puerto Caldera to Colón
Operated By: Ponant (Cruise)
Embark on a 7 night cruise with Ponant visiting Costa Rica & Panama, beginning your journey in Puerto Caldera and travelling through to Colón.
Departs: 11 January 2021
Regions: Central America
 
From
$ 4,190
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8 Day Costa Rica to Panama with Intrepid
New 2019  Tour  

8 Days San Jose to Panama City
Operated By: Intrepid (Small Group Adventure)
Discover Costa Rica & Panama on this new 8 day small group adventure with Intrepid, beginning your journey in San Jose and travelling through to Panama City....
Departures: Oct 2020 to Dec 2020 (3 Departures)
Countries Visited: Costa Rica, Panama
Save
$ 87
From
$ 2,011
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12 Day The Panama Canal & Costa Rica - Eastbound with Tauck
Cruise  

12 Days San Jose to Panama City
Operated By: Tauck (Small Ship Cruise)
Embark on a 11 night small ship cruise with Tauck visiting Costa Rica & Panama, beginning your journey in San Jose and travelling through to Panama City.
Exclusive: 1 Night Free!
Departures: Jan 2021 to Feb 2021 (2 Departures)
Regions: Central America
Save
$ 228
From
$ 10,868
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14 Day Panama Experience: Cloud Forests & Canals with G Adventures
Tour  

14 Days San Jose to Panama City
Operated By: G Adventures (Small Group Tour)
Discover Costa Rica & Panama on this 14 day small group tour with G Adventures, beginning your journey in San Jose and travelling through to Panama City.
Departures: Sep 2020 to May 2022 (26 Departures)
Countries Visited: Costa Rica, Panama
Save
$ 258
From
$ 1,161
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13 Day Costa Rica & Panama Discovery with Intrepid
Tour  

13 Days San Jose to Panama City
Operated By: Intrepid (Small Group Adventure)
Discover Costa Rica & Panama on this 13 day small group adventure with Intrepid, beginning your journey in San Jose and travelling through to Panama City.
Departures: Nov 2020 to Dec 2021 (35 Departures)
Countries Visited: Costa Rica, Panama
Save
$ 73
From
$ 1,613
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8 Day Natural & Cultural History of Central America with Ponant
Cruise  

8 Days Colon to Puerto Calderda
Operated By: Ponant (Cruise)
Ship: Le Champlain
Embark on a 7 night cruise with Ponant visiting Panama & Costa Rica, beginning your journey in Colon and travelling through to Puerto Calderda.
Departs: 29 December 2020
Regions: Central America
 
From
$ 5,580
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15 Day Cycle Nicaragua, Costa Rica & Panama with Intrepid
Tour  

15 Days Granada to Panama City
Operated By: Intrepid (Small Group Adventure)
Travel to South & Central America and journey through Nicaragua, Costa Rica & Panama on this 15 day small group adventure with Intrepid.
Departures: Oct 2020 to Nov 2020 (2 Departures)
Countries Visited: Nicaragua, Costa Rica, Panama
Save
$ 167
From
$ 3,998
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8 Day Christmas between Mexico & Panama with Ponant
Cruise  

8 Days Cozumel to Colon
Operated By: Ponant (Cruise)
Ship: Le Champlain
Embark on a 7 night cruise with Ponant visiting Mexico, Costa Rica & Panama, beginning your journey in Cozumel and travelling through to Colon.
Departs: 22 December 2020
Regions: Central America
 
From
$ 4,670
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14 Day Cycle Nicaragua to the Panama Canal with Explore
Tour  

14 Days Granada to Panama City
Operated By: Explore (Small Group Adventure)
Travel to South & Central America and journey through Nicaragua, Costa Rica & Panama on this 14 day small group adventure with Explore.
Departures: Jan 2021 to Nov 2021 (5 Departures)
Countries Visited: Nicaragua, Costa Rica, Panama
Save
$ 195
From
$ 4,685
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15 Day Cycle Nicaragua, Costa Rica & Panama with Exodus
Tour  

15 Days Granada to Panama City
Operated By: Exodus (Small Group Adventure)
Travel to South & Central America and journey through Costa Rica, Nicaragua & Panama on this 15 day small group adventure with Exodus.
Departures: Nov 2020 to Dec 2021 (15 Departures)
Countries Visited: Costa Rica, Nicaragua, Panama
Save
$ 246
From
$ 5,519
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10 Day Panama & Colombia Discovery with Scenic
Cruise  

10 Days Cartagena to Lima
Operated By: Scenic (Discovery Voyage)
Embark on a 9 night discovery voyage with Scenic visiting Colombia, Panama & Peru, beginning your journey in Cartagena and travelling through to Lima.
Departs: 16 October 2021
Regions: Central America
Save
$ 383
From
$ 12,377
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9 Day Colon to Guayaquil with Silversea
Cruise  

9 Days Colon to Guayaquil
Operated By: Silversea (Cruise)
Embark on a 8 night cruise with Silversea visiting Panama, Colombia & Ecuador, beginning your journey in Colon and travelling through to Guayaquil.
Departs: 31 October 2020
Regions: South America
 
From
$ 8,100
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18 Day Colombia Experience with Panama & Colombia Discovery with Scenic
Tour + Cruise  

18 Days Bogota to Lima
Operated By: Scenic (Discovery Voyage)
Travel to South & Central America and journey through Colombia, Panama & Peru on this 18 day discovery voyage with Scenic.
Departs: 08 October 2021
Countries Visited: Colombia, Panama, Peru
Save
$ 599
From
$ 19,371
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8 Day Christmas Between Mexico & Panama with Ponant
Cruise  

8 Days Cancun to Colon
Operated By: Ponant (Cruise)
Ship: Le Champlain
Embark on a 7 night cruise with Ponant visiting Mexico, Costa Rica & Panama, beginning your journey in Cancun and travelling through to Colon.
Departs: 22 December 2020
Regions: Central America
 
From
$ 4,200
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12 Day Caribbean Delights with Scenic
Cruise  

12 Days Nassau to Cartagena
Operated By: Scenic (Discovery Voyage)
Visit 5 different countries on this 11 night discovery voyage with Scenic, beginning your journey in Nassau and travelling through to Cartagena.
Departs: 05 October 2021
Regions: Caribbean
Save
$ 435
From
$ 14,065
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25 Day Central American Explorer with Explore
Tour  

25 Days Panama City to Antigua
Operated By: Explore (Small Group Adventure)
Tour through 5 different countries on this 25 day small group adventure with Explore, beginning your journey in Panama City and travelling through to Antigua.
Departures: Feb 2021 to Nov 2021 (2 Departures)
Countries Visited: Panama, Costa Rica, Nicaragua, Honduras, Guatemala
Save
$ 245
From
$ 5,875
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12 Day Southern Caribbean Cruise with Royal Caribbean
Cruise  

12 Days Fort Lauderdale to Fort Lauderdale
Operated By: Royal Caribbean (Cruise)
Visit 5 different countries on this 11 night cruise with Royal Caribbean, beginning and ending your journey in Fort Lauderdale.
Exclusive: July Sale
Departs: 22 November 2021
Regions: Caribbean
 
From
$ 1,579
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9 Day Southern Caribbean with Norwegian Cruise Line
Cruise  

9 Days Panama City to Panama City
Operated By: Norwegian Cruise Line (Cruise)
Visit 5 different countries on this 8 night cruise with Norwegian Cruise Line, beginning and ending your journey in Panama City.
Exclusive: Free At Sea
Departs: 02 March 2022
Regions: Caribbean
 
From
$ 1,565
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12 Day Ultimate Caribbean Holiday with Celebrity Cruises
Cruise  

12 Days Tampa to Tampa
Operated By: Celebrity Cruises (Cruise)
Visit 5 different countries on this 11 night cruise with Celebrity Cruises, beginning and ending your journey in Tampa.
Departs: 23 December 2021
Regions: Caribbean
 
From
$ 3,270
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11 Day Eastern Caribbean Holiday with Royal Caribbean
Cruise  

11 Days Miami to Miami
Operated By: Royal Caribbean (Cruise)
Visit 5 different countries on this 10 night cruise with Royal Caribbean, beginning and ending your journey in Miami.
Exclusive: July Sale
Departs: 30 December 2021
Regions: Caribbean
 
From
$ 2,476
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29 Day Amazing Central America with Intrepid
Tour  

29 Days Antigua to Panama City
Operated By: Intrepid (Small Group Adventure)
Tour through 6 different countries on this 29 day small group adventure with Intrepid, beginning your journey in Antigua and travelling through to Panama City.
Departures: Oct 2020 to Dec 2021 (32 Departures)
Countries Visited: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Save
$ 165
From
$ 3,648
View
20 Day Ultimate America Discovery with Scenic
Cruise  

20 Days Boston to Cartagena
Operated By: Scenic (Discovery Voyage)
Visit 6 different countries on this 19 night discovery voyage with Scenic, beginning your journey in Boston and travelling through to Cartagena.
Exclusive: Limited Time Sale
Departs: 27 September 2021
Regions: Caribbean, Central America, USA
Save
$ 2,571
From
$ 19,089
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