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All Panama Tours & Cruises

Explore the colors and natural beauty of Panama - a land between the seas. Travel via dugout canoe to meet the indigenous Emberá people, visit gorgeous islands, snorkel the Caribbean and cruise through the world-famous Panama Canal. Choose from 128 cruises, small gropup tours and adventures to Panama. Compare trips, read past passenger reviews and enjoy exclusive savings on every departure.

  128 Trips Found
9 Day Discover Panama with Collette
Tour  

9 Days Panama City to Playa Bonita
Operated By: Collette (Guided Tour)
Journey to Panama on this 9 day guided tour with Collette, beginning your journey in Panama City and travelling through to Playa Bonita.
Departs: 22 April 2021
Countries Visited: Panama
Save
$ 150
From
$ 2,449
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8 Day Cruising Costa Rica & Panama with Peregrine Adventures
Cruise  

8 Days Puerto Caldera to Colon
Operated By: Peregrine Adventures (Adventure Cruise)
Embark on a 7 night adventure cruise with Peregrine Adventures visiting Costa Rica & Panama, beginning your journey in Puerto Caldera and travelling through to Colon...
Departures: Jan 2022 to Feb 2022 (2 Departures)
Regions: Central America
Save
$ 82
From
$ 4,038
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8 Day Cruising Costa Rica and Panama with Peregrine Adventures
Cruise  

8 Days Colon to Puerto Caldera
Operated By: Peregrine Adventures (Adventure Cruise)
Embark on a 7 night adventure cruise with Peregrine Adventures visiting Costa Rica & Panama, beginning your journey in Colon and travelling through to Puerto Caldera...
Departures: Jan 2022 to Mar 2022 (4 Departures)
Regions: Central America
Save
$ 82
From
$ 4,038
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13 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour  

13 Days San Jose to Panama City
Operated By: Intrepid Travel (Small Group Adventure)
Discover Costa Rica & Panama on this 13 day small group adventure with Intrepid Travel, beginning your journey in San Jose and travelling through to Panama City....
Departures: May 2021 to Dec 2022 (48 Departures)
Countries Visited: Costa Rica, Panama
Save
$ 77
From
$ 1,627
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9 Day Peru to Panama Along the Andean Coast with Scenic
Cruise  

9 Days Lima to Panama City
Operated By: Scenic (Cruise)
Embark on a 8 night cruise with Scenic visiting Colombia, Panama & Peru, beginning your journey in Lima and travelling through to Panama City.
Exclusive: Mutiple Deals Available
Departs: 27 March 2023
Regions: Central America
Save
$ 732
From
$ 9,603
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14 Day Cycle Nicaragua to the Panama Canal with Explore!
Tour  

14 Days Granada to Panama City
Operated By: Explore! (Small Group Adventure)
Travel to South & Central America and journey through Nicaragua, Costa Rica & Panama on this 14 day small group adventure with Explore!.
Departures: Oct 2021 to Nov 2022 (8 Departures)
Countries Visited: Nicaragua, Costa Rica, Panama
Save
$ 397
From
$ 4,483
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15 Day Cycle Nicaragua, Costa Rica & Panama with Exodus Travels
Tour  

15 Days Granada to Panama City
Operated By: Exodus Travels (Small Group Adventure)
Travel to South & Central America and journey through Costa Rica, Nicaragua & Panama on this 15 day small group adventure with Exodus Travels.
Departures: Jul 2021 to Dec 2022 (20 Departures)
Countries Visited: Costa Rica, Nicaragua, Panama
Save
$ 259
From
$ 5,903
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10 or 9 Day Panama & Colombia Discovery with Scenic
Cruise  

10 or 9 Days Cartagena to Lima or Panama City to Lima
Operated By: Scenic (Cruise)
Visit 4 different countries on this 9 night cruise with Scenic, beginning your journey in Cartagena and travelling through to Lima.
Exclusive: Mutiple Deals Available
Departures: Oct 2021 to Oct 2023 (2 Departures)
Regions: Central America
Save
$ 1,379
From
$ 9,888
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18 Day Colombia Experience with Panama & Colombia Discovery with Scenic
Tour + Cruise  

18 Days Bogota to Lima
Operated By: Scenic (Discovery Voyage)
Travel to South & Central America and journey through Colombia, Panama & Peru on this 18 day discovery voyage with Scenic.
Departs: 08 October 2021
Countries Visited: Colombia, Panama, Peru
Save
$ 521
From
$ 18,999
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12 Day Puntarenas to Guayaquil with Silversea
Cruise  

12 Days Puntarenas to Guayaquil
Operated By: Silversea (Cruise)
Ship: Silver Wind
Visit 4 different countries on this 11 night cruise with Silversea, beginning your journey in Puntarenas and travelling through to Guayaquil.
Exclusive: Fly Offers Available
Departs: 27 October 2022
Regions: South America
 
From
$ 9,270
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16 Day Andean Coast – Expedition from Jungle to Desert (Itinerary 1) with Hurtigruten
Cruise  

16 Days Panama City to Valparaiso
Operated By: Hurtigruten (Expedition Cruise)
Visit 4 different countries on this 15 night expedition cruise with Hurtigruten, beginning your journey in Panama City and travelling through to Valparaiso.
Departs: 08 October 2021
Regions: South America
 
From
$ 7,033
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15 Day Panama and Peru – Through the Panama Canal and Along the Andean Coast with Hurtigruten
Cruise  

15 Days Colon to Valparaiso
Operated By: Hurtigruten (Expedition Cruise)
Ship: MS Fram
Visit 4 different countries on this 14 night expedition cruise with Hurtigruten, beginning your journey in Colon and travelling through to Valparaiso.
Departs: 01 October 2021
Regions: South America
 
From
$ 6,435
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16 Day Andean Coast – Expedition from Jungle to Desert (Itinerary 2) with Hurtigruten
Cruise  

16 Days Panama City to Valparaiso
Operated By: Hurtigruten (Expedition Cruise)
Visit 4 different countries on this 15 night expedition cruise with Hurtigruten, beginning your journey in Panama City and travelling through to Valparaiso.
Departs: 18 October 2021
Regions: South America
 
From
$ 7,334
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15 Day Inca History, Colonial Highlights & The Panama Canal with Hurtigruten
Cruise  

15 Days Colon to Valparaiso
Operated By: Hurtigruten (Expedition Cruise)
Visit 4 different countries on this 14 night expedition cruise with Hurtigruten, beginning your journey in Colon and travelling through to Valparaiso.
Departures: Oct 2022 to Oct 2022 (2 Departures)
Regions: Central America, South America
 
From
$ 6,584
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12 Day Caribbean Delights with Scenic
Cruise  

12 Days Nassau to Cartagena
Operated By: Scenic (Cruise)
Visit 5 different countries on this 11 night cruise with Scenic, beginning your journey in Nassau and travelling through to Cartagena.
Exclusive: Mutiple Deals Available
Departs: 05 October 2021
Regions: Caribbean
Save
$ 1,798
From
$ 12,702
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12 Day Southern Caribbean Cruise with Royal Caribbean
Cruise  

12 Days Fort Lauderdale to Fort Lauderdale
Operated By: Royal Caribbean (Cruise)
Visit 5 different countries on this 11 night cruise with Royal Caribbean, beginning and ending your journey in Fort Lauderdale.
Exclusive: Jump In To 2021 Sale
Departs: 22 November 2021
Regions: Caribbean
 
From
$ 1,630
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15 Day Panama Canal with Cunard
Cruise  

15 Days Los Angeles to Fort Lauderdale
Operated By: Cunard (Cruise)
Visit 5 different countries on this 14 night cruise with Cunard, beginning your journey in Los Angeles and travelling through to Fort Lauderdale.
Departs: 26 July 2022
Regions: Central America
 
From
$ 2,849
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9 Day Southern Caribbean with Norwegian Cruise Line
Cruise  

9 Days Panama City to Panama City
Operated By: Norwegian Cruise Line (Cruise)
Visit 5 different countries on this 8 night cruise with Norwegian Cruise Line, beginning and ending your journey in Panama City.
Exclusive: Free At Sea
Departs: 02 March 2022
Regions: Caribbean
 
From
$ 1,079
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10 Day Panama Canal-Panama City with Norwegian Cruise Line
Cruise  

10 Days Panama City to Panama City
Operated By: Norwegian Cruise Line (Cruise)
Visit 5 different countries on this 9 night cruise with Norwegian Cruise Line, beginning and ending your journey in Panama City.
Exclusive: Free At Sea
Departs: 02 November 2021
Regions: Caribbean
 
From
$ 1,407
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16 Day Caribbean Sea - Discover Cayes, Coves and Cultures (Itinerary 2) with Hurtigruten
Cruise  

16 Days Miami to Colon
Operated By: Hurtigruten (Expedition Cruise)
Ship: MS Fram
Visit 5 different countries on this 15 night expedition cruise with Hurtigruten, beginning your journey in Miami and travelling through to Colon.
Departs: 16 September 2021
Regions: Central America
 
From
$ 5,684
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18 Day Panama Canal, Native Communities And Cultures with Hurtigruten
Cruise  

18 Days Colon to Valparaiso
Operated By: Hurtigruten (Expedition Cruise)
Ship: MS Fram
Visit 5 different countries on this 17 night expedition cruise with Hurtigruten, beginning your journey in Colon and travelling through to Valparaiso.
Departs: 29 September 2022
Regions: Central America, South America
 
From
$ 7,035
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25 Day Central American Explorer with Explore!
Tour  

25 Days Panama City to Antigua
Operated By: Explore! (Small Group Adventure)
Tour through 5 different countries on this 25 day small group adventure with Explore!, beginning your journey in Panama City and travelling through to Antigua.
Departures: Nov 2021 to Nov 2022 (5 Departures)
Countries Visited: Costa Rica, Panama, Guatemala, Honduras, Nicaragua
Save
$ 455
From
$ 5,770
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17 Day Panama Canal with Cunard
Cruise  

17 Days Fort Lauderdale to San Francisco
Operated By: Cunard (Cruise)
Visit 5 different countries on this 16 night cruise with Cunard, beginning your journey in Fort Lauderdale and travelling through to San Francisco.
Departs: 21 January 2022
Regions: Central America
 
From
$ 5,844
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18 Day Diverse Cultures And National Parks Of Latin America with Hurtigruten
Cruise  

18 Days Valparaiso to Puntarenas
Operated By: Hurtigruten (Expedition Cruise)
Visit 5 different countries on this 17 night expedition cruise with Hurtigruten, beginning your journey in Valparaiso and travelling through to Puntarenas.
Departs: 03 April 2022
Regions: South America
 
From
$ 7,185
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9 Day Southern Caribbean with Norwegian Cruise Line
Cruise  

9 Days Panama City to Panama City
Operated By: Norwegian Cruise Line (Cruise)
Visit 5 different countries on this 8 night cruise with Norwegian Cruise Line, beginning and ending your journey in Panama City.
Exclusive: Free At Sea
Departs: 04 March 2023
Regions: Central America
 
From
$ 1,584
View
17 Day Panama Canal with Cunard
Cruise  

17 Days San Francisco to Fort Lauderdale
Operated By: Cunard (Cruise)
Visit 5 different countries on this 16 night cruise with Cunard, beginning your journey in San Francisco and travelling through to Fort Lauderdale.
Departs: 24 July 2022
Regions: Central America
 
From
$ 3,149
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12 Day Ultimate Caribbean Holiday with Celebrity Cruises
Cruise  

12 Days Tampa to Tampa
Operated By: Celebrity Cruises (Cruise)
Visit 5 different countries on this 11 night cruise with Celebrity Cruises, beginning and ending your journey in Tampa.
Exclusive: Always Included
Departures: Dec 2021 to Mar 2023 (2 Departures)
Regions: Caribbean
 
From
$ 2,693
View
11 Day Eastern Caribbean Holiday with Royal Caribbean
Cruise  

11 Days Miami to Miami
Operated By: Royal Caribbean (Cruise)
Visit 5 different countries on this 10 night cruise with Royal Caribbean, beginning and ending your journey in Miami.
Exclusive: Jump In To 2021 Sale
Departs: 30 December 2021
Regions: Caribbean
 
From
$ 2,327
View
11 Day Tropical Waters And Remote Island Communities In The Caribbean with Hurtigruten
Cruise  

11 Days Miami to Colon
Operated By: Hurtigruten (Expedition Cruise)
Visit 5 different countries on this 10 night expedition cruise with Hurtigruten, beginning your journey in Miami and travelling through to Colon.
Departs: 28 September 2022
Regions: Caribbean, Central America
 
From
$ 4,784
View
12 Day Andean Coastal Exploration with Scenic
Cruise  

12 Days San Jose to Lima
Operated By: Scenic (Cruise)
Visit 5 different countries on this 11 night cruise with Scenic, beginning your journey in San Jose and travelling through to Lima.
Exclusive: Mutiple Deals Available
Departs: 11 October 2022
Regions: Central America, South America
Save
$ 1,002
From
$ 12,768
View

Results 1-30 of 128
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