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All Panama Tours & Cruises

Explore the colors and natural beauty of Panama - a land between the seas. Travel via dugout canoe to meet the indigenous Emberá people, visit gorgeous islands, snorkel the Caribbean and cruise through the world-famous Panama Canal. Choose from 1,258 cruises, small group tours and adventures to Panama travelling with the world's leading tour operators.
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373 Trips (1,258 Departures)
373 Trips (1,258 Departures)
Departures
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Duration
6 Days
171 Days
Types
Budget
Start & End Cities
Operators
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Price
$1,000pp
$147,495pp
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6 Day Independent Panama with Globus
New ReleaseTour

6 Days Panama City to Panama City
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Styles: Short Break, Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$2,715
Save 105
Per Person
View Trip
9 Day Independent Panama with the Pacific Coast with Globus
New ReleaseTour

9 Days Panama City to Pacific Coast
Operator: Globus
Departures: Nov 2026 to Mar 2028
Trip Style: Scenic
Visits: Panama
Exclusive Savings
From (Per Person)
A$4,092
Save 161
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Nov 2026 to Feb 2028
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,102
Save 437
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$11,080
Suite
$18,510
From (Per Person)
A$11,080
Save 1,140
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Operator: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$10,272
Suite
$14,938
From (Per Person)
A$10,272
Save 288
Per Person
View Trip
11 Day From Panama’s Wild Beauty to Peruvian Shores with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Lima
Operator: Ponant
Ship: L'Austral
Departure: 20 October 2026
Visits: Panama, Peru
Exclusive Savings
Oceanview
$8,452
Balcony
$9,101
Suite
$16,939
From (Per Person)
A$8,452
Save 218
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$7,750
Suite
$14,143
From (Per Person)
A$7,750
Save 272
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Colon
Operator: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Mar 2027
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$8,808
Suite
$13,367
From (Per Person)
A$8,808
Save 242
Per Person
View Trip
8 Day Coastal Adventures: Panama & Costa Rica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Panama City to San Jose
Operator: Emerald Cruises
Ships: Emerald Azzurra
Departures: Jan 2028 to Jan 2029
Visits: Panama, Costa Rica
Exclusive Savings
Oceanview
$8,150
Balcony
-
Suite
$10,301
From (Per Person)
A$8,150
Save 2,647
Per Person
View Trip
8 Day Coastal Adventures: Costa Rica & Panama with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) San Jose to Panama City
Operator: Emerald Cruises
Ships: Emerald Azzurra
Departures: Feb 2028 to Feb 2029
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$8,150
Balcony
-
Suite
$10,301
From (Per Person)
A$8,150
Save 2,646
Per Person
View Trip
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys with Ponant
Cruise
 (2)

8 Days (7 Nights) Puntarenas to Colon
Operator: Ponant
Ship: Le Laperouse
Departure: 19 February 2027
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$11,077
Suite
$18,508
From (Per Person)
A$11,077
Save 313
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$10,789
Suite
$17,996
From (Per Person)
A$10,789
Save 433
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Operator: Ponant
Ship: Le Bougainville
Departure: 23 February 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$14,398
Suite
$21,935
From (Per Person)
A$14,398
Save 402
Per Person
View Trip
13 Day Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Operator: Emerald Cruises
Ships: Emerald Azzurra
Departures: Feb 2028 to Feb 2029
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$14,745
Balcony
-
Suite
$17,621
From (Per Person)
A$14,745
Save 4,233
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Operator: Ponant
Ship: Le Bellot
Departure: 18 December 2026
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$14,698
Suite
$22,420
From (Per Person)
A$14,698
Save 412
Per Person
View Trip
13 Day Costa Rica, Panama from the Atlantic to the Pacific via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Operator: Emerald Cruises
Ship: Emerald Azzurra
Departure: 31 January 2029
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$14,645
Balcony
-
Suite
$17,521
From (Per Person)
A$14,645
Save 4,220
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operator: G Adventures
Departures: Dec 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,645
Save 954
Per Person
View Trip
11 Day Wonders of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Cartagena to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,063
Suite
$10,155
From (Per Person)
A$8,063
Save 1,785
Per Person
View Trip
14 Day Magic of Colombia (MedellÍn & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

14 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$8,999
Suite
$12,568
From (Per Person)
A$8,999
Save 1,879
Per Person
View Trip
16 Day Wonders of Colombia (MedellÍn, Cartagena & Panama Extensions) with AmaWaterways
New ReleaseTour + River Cruise

16 Days Medellin to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$11,708
Suite
$13,800
From (Per Person)
A$11,708
Save 1,929
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Dec 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,469
Save 530
Per Person
View Trip
12 Day The Panama Canal & Costa Rica - Eastbound with Tauck
Tour + Cruise

12 Days Puntarenas to Panama City
Operator: Tauck
Cruise Line: Ponant
Ship: Le Lapérouse
Departure: 03 February 2027
Trip Styles: Coach, Cruise, Scenic
Visits: Costa Rica, Panama
Complimentary Hotel Night
From (Per Person)
A$13,999
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operator: Intrepid
Departures: Dec 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$2,812
Save 219
Per Person
View Trip
11 Day Magic of Colombia (Panama Extension) with AmaWaterways
New ReleaseTour + River Cruise

11 Days Barranquilla to Panama City
Operator: AmaWaterways
Ships: AmaMagdalena, AmaMelodia
Departures: Oct 2026 to Dec 2027
Rivers: Magdalena
Visits: Colombia, Panama
Exclusive Savings
Balcony
$7,923
Suite
$10,155
From (Per Person)
A$7,923
Save 1,785
Per Person
View Trip
12 Day Costa Rica & the Panama Canal with Aurora Expeditions
New ReleaseCruise

12 Days (11 Nights) San Jose to Panama City
Operator: Aurora Expeditions
Ships: Sylvia Earle, Douglas Mawson
Departures: Apr 2027 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Oceanview
$24,346
Balcony
$24,448
Suite
$39,017
From (Per Person)
A$24,346
Per Person
View Trip
12 Day The Panama Canal & Costa Rica - Westbound with Tauck
Tour + Cruise

12 Days Panama City to San Jose
Operator: Tauck
Cruise Line: Ponant
Ship: Le Lapérouse
Departure: 10 February 2027
Trip Styles: Coach, Cruise, Scenic
Visits: Panama, Costa Rica
Complimentary Hotel Night
From (Per Person)
A$13,999
Per Person
View Trip
10 Day Panama and Costa Rica: Crossing the Canal with Aurora Expeditions
New ReleaseCruise

10 Days (9 Nights) Panama City to San Jose
Operator: Aurora Expeditions
Ship: Douglas Mawson
Departure: 04 October 2027
Visits: Panama, Costa Rica
Exclusive Savings
Oceanview
$17,304
Balcony
$18,331
Suite
$27,573
From (Per Person)
A$18,331
Per Person
View Trip
14 Day Cycle Nicaragua to the Panama Canal with Explore Worldwide
Tour

14 Days Granada to Panama City
Operator: Explore
Departures: Jan 2027 to Nov 2027
Trip Styles: Adventure, Cycling
Visits: Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$7,392
Save 548
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visits: Bahamas, Colombia, Panama
Exclusive Savings
Balcony
$12,056
Suite
$12,742
From (Per Person)
A$12,056
Save 3,689
Per Person
View Trip
7 Day Callao (Lima) to Fuerte Amador with Crystal Cruises
Cruise

7 Days (6 Nights) Lima to Panama City
Operator: Crystal
Ship: Crystal Serenity
Departure: 05 December 2027
Visits: Peru, Ecuador, Panama
Exclusive Savings
Oceanview
$4,800
Balcony
$5,677
Suite
$5,589
From (Per Person)
A$4,800
Save 600
Per Person
View Trip
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