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All Panama Tours & Cruises

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384 Trips (895 Trip Departures)
18 Day Costa Rica, Mexico & Hawaiian Nights with Seabourn
Cruise

18 Days (17 Nights) Panama City to Honolulu
Cruise Line: Seabourn
Ship: Seabourn Encore
Departure: 12 December 2025
Visit: Panama, Costa Rica, Mexico, USA
More Moments On Us Offer
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,223
Suite
$7,379
From
US$5,223
Per Person
View Trip
8 Day Southern Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 19 December 2026
Visit: Panama, Colombia, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$1,087
Oceanview
$1,164
Balcony
$1,761
Suite
$1,967
From
US$1,087
Save 424
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 18 January 2026
Visit: Colombia, Bonaire, Aruba, Panama
Bonus Onboard Credit
Inside
$1,644
Oceanview
$1,187
Balcony
$1,207
Suite
$1,317
From
US$1,187
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 03 April 2027
Visit: USA, Aruba, Panama, Mexico
Princess Premier
Princess Standard
Inside
$1,929
Oceanview
$2,229
Balcony
$4,044
Suite
$6,763
From
US$1,929
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2025 to Apr 2026
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,077
Oceanview
$1,078
Balcony
$1,314
Suite
$1,899
From
US$1,077
Save 539
Per Person
View Trip
19 Day New York To San Francisco with Cunard
Cruise
 (5)

19 Days (18 Nights) New York to San Francisco
Cruise Line: Cunard
Ship: Queen Mary 2
Departure: 19 January 2026
Visit: USA, Curacao, Panama, Mexico
Inside
$2,249
Oceanview
$2,909
Balcony
$2,999
Suite
-
From
US$2,249
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) Cartagena to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Nov 2026 to Apr 2027
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$905
Oceanview
$1,005
Balcony
$1,432
Suite
$1,717
From
US$905
Save 376
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Jan 2027
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$910
Oceanview
$1,020
Balcony
$1,138
Suite
$1,741
From
US$910
Save 466
Per Person
View Trip
13 Day World Cruise: Panama Canal To Callao with Seabourn
Cruise

13 Days (12 Nights) Miami to Lima
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru
More Moments On Us Offer
Exclusive Savings
Inside
-
Oceanview
$6,504
Balcony
$8,170
Suite
-
From
US$6,504
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 04 October 2026
Visit: USA, Mexico, Panama, Aruba
Princess Premier
Princess Standard
Inside
$1,549
Oceanview
$1,649
Balcony
$2,924
Suite
$5,411
From
US$1,549
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 20 December 2026
Visit: Colombia, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,186
Oceanview
$1,326
Balcony
$1,833
Suite
$2,158
From
US$1,186
Save 432
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 March 2026
Visit: Panama, Colombia, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$1,136
Oceanview
$1,187
Balcony
$1,374
Suite
$2,238
From
US$1,136
Save 444
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico
Inside
$1,660
Oceanview
$2,250
Balcony
$2,968
Suite
$7,859
From
US$1,660
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 17 January 2026
Visit: Panama, Colombia, Bonaire, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$1,166
Oceanview
$1,087
Balcony
$1,173
Suite
$1,818
From
US$1,087
Save 423
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Jan 2026 to Mar 2026
Visit: Colombia, Bonaire, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,122
Oceanview
$1,172
Balcony
$1,280
Suite
$1,894
From
US$1,122
Save 803
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2025 to Apr 2026
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$890
Oceanview
$941
Balcony
$1,127
Suite
$2,392
From
US$890
Save 513
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Dec 2025 to Feb 2027
Visit: Panama, Colombia, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$885
Oceanview
$995
Balcony
$1,156
Suite
$1,708
From
US$885
Save 826
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 29 March 2026
Visit: Colombia, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,372
Oceanview
$1,422
Balcony
$1,659
Suite
$2,224
From
US$1,372
Save 551
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departure: 05 October 2026
Visit: USA, Bahamas, Colombia, Panama
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$23,597
Suite
-
From
US$23,597
Save 24,793
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Jan 2027
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$951
Oceanview
$1,071
Balcony
$1,345
Suite
$1,833
From
US$951
Save 487
Per Person
View Trip
11 Day Panama Canal Westward Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Colon to Los Angeles
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 25 April 2026
Visit: Panama, Costa Rica, Mexico, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$1,125
Oceanview
$1,447
Balcony
$2,130
Suite
$4,107
From
US$1,125
Save 307
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 21 December 2025
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,587
Oceanview
$1,596
Balcony
$1,909
Suite
$6,360
From
US$1,587
Save 643
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Jan 2026 to Mar 2026
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,187
Oceanview
$1,108
Balcony
$1,204
Suite
$1,989
From
US$1,108
Save 637
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Jan 2026 to Feb 2027
Visit: Colombia, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$927
Oceanview
$1,046
Balcony
$1,312
Suite
$1,788
From
US$927
Save 518
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Jan 2026 to Mar 2026
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$979
Oceanview
$1,030
Balcony
$1,197
Suite
$1,861
From
US$979
Save 487
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2025 to Nov 2025
Visit: Colombia, Bonaire, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,073
Oceanview
$1,277
Balcony
$1,114
Suite
$1,985
From
US$1,073
Save 655
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 December 2025
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,499
Oceanview
$1,549
Balcony
$1,646
Suite
$2,437
From
US$1,499
Save 605
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Nov 2025 to Apr 2027
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$816
Oceanview
$869
Balcony
$1,299
Suite
$1,630
From
US$816
Save 500
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

7 Days (6 Nights) Cartagena to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 19 April 2026
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$906
Oceanview
$1,006
Balcony
$1,243
Suite
$2,343
From
US$906
Save 358
Per Person
View Trip
11 Day Tropical Tastes Of The Riviera with Regent Seven Seas
Cruise

11 Days (10 Nights) Panama City to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 January 2026
Visit: Panama, Costa Rica, Mexico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,715
Suite
$8,107
From
US$7,715
Save 12,183
Per Person
View Trip
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