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All Panama Tours & Cruises

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342 Trips (1,086 Trip Departures)
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$815
Oceanview
$825
Balcony
$1,172
Suite
$1,080
From
US$815
Save 934
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 27 September 2027
Visit: USA, Mexico, Panama, Colombia
Inside
$1,939
Oceanview
$2,129
Balcony
$2,794
Suite
$8,974
From
US$1,939
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 20 December 2026
Visit: Colombia, Aruba, Bonaire, Panama
Exclusive Savings
Inside
$1,750
Oceanview
$1,780
Balcony
$2,264
Suite
$2,228
From
US$1,750
Save 870
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 18 March 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$919
Oceanview
$1,049
Balcony
$1,469
Suite
$1,499
From
US$919
Save 508
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico
Inside
$1,608
Oceanview
$2,102
Balcony
$2,928
Suite
$10,042
From
US$1,608
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$868
Oceanview
$998
Balcony
$1,408
Suite
$1,422
From
US$868
Save 701
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Mar 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$866
Oceanview
$994
Balcony
$1,296
Suite
$1,164
From
US$866
Save 1,114
Per Person
View Trip
8 Day Southern Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 19 December 2026
Visit: Panama, Colombia, Aruba, Bonaire
Exclusive Savings
Inside
$1,039
Oceanview
$1,079
Balcony
$1,462
Suite
$1,557
From
US$1,039
Save 600
Per Person
View Trip
17 Day Panama Canal - Ocean To Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 10 October 2027
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,399
Oceanview
$1,699
Balcony
$2,299
Suite
$3,449
From
US$1,399
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 14 February 2027
Visit: Colombia, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$886
Oceanview
$1,079
Balcony
$1,498
Suite
$1,498
From
US$886
Save 507
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 03 April 2027
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Sanctuary Collection
Inside
$1,429
Oceanview
$2,199
Balcony
$3,099
Suite
$5,379
From
US$1,429
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) Cartagena to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Nov 2026 to Apr 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$900
Oceanview
$940
Balcony
$1,321
Suite
$1,177
From
US$900
Save 583
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 04 October 2026
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,559
Oceanview
$2,259
Balcony
$2,299
Suite
$3,749
From
US$1,559
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visit: USA, Bahamas, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$26,140
Suite
$56,695
From
US$26,140
Per Person
View Trip
11 Day Panama Canal Westward Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Colon to Los Angeles
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 25 April 2026
Visit: Panama, Costa Rica, Mexico, USA
Exclusive Savings
Inside
$732
Oceanview
$890
Balcony
$1,512
Suite
-
From
US$732
Save 336
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2028
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Inside
$1,757
Oceanview
$2,127
Balcony
$3,297
Suite
$11,097
From
US$1,757
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia
Inside
$1,434
Oceanview
$1,637
Balcony
$2,098
Suite
$10,589
From
US$1,434
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,457
Oceanview
$1,667
Balcony
$1,745
Suite
$1,967
From
US$1,457
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,567
Oceanview
$1,877
Balcony
$2,921
Suite
$3,777
From
US$1,567
Per Person
View Trip
20 Day Panama Canal & the Americas with Viking Cruises
Cruise

20 Days (19 Nights) Santiago to New York
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Apr 2027 to Apr 2028
Visit: Chile, Peru, Panama, Jamaica, Bahamas
Flights Included
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,995
Suite
$16,495
From
US$10,995
Save 1,000
Per Person
View Trip
18 Day New York To Los Angeles with Cunard
Cruise
 (1)

18 Days (17 Nights) New York to Los Angeles
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 January 2027
Visit: USA, Aruba, Panama, El Salvador, Mexico
Bonus Onboard Credit
Inside
$2,599
Oceanview
$3,559
Balcony
$4,269
Suite
$10,179
From
US$2,599
Per Person
View Trip
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise
 (5)

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico, Colombia, Panama, Costa Rica
Viking $499 Air Deal
Inside
-
Oceanview
-
Balcony
$6,399
Suite
$11,999
From
US$6,399
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Mar 2027 to Mar 2027
Visit: Panama, Colombia, Curacao, Bonaire, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$987
Oceanview
$1,087
Balcony
$1,499
Suite
$1,599
From
US$987
Save 555
Per Person
View Trip
15 Day Grand World Voyage with Holland America
Cruise

15 Days (14 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 03 May 2026
Visit: USA, Mexico, El Salvador, Panama, Colombia
Advantage Fare
Inside
$2,399
Oceanview
$3,249
Balcony
$6,699
Suite
-
From
US$2,399
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Princess
Ship: Island Princess
Departure: 13 January 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,937
Oceanview
$2,112
Balcony
$2,967
Suite
$3,609
From
US$1,937
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 18 March 2028
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,650
Oceanview
$1,900
Balcony
$3,150
Suite
$4,239
From
US$1,650
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 23 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Drinks + WiFi
Inside
$1,025
Oceanview
$1,129
Balcony
$1,364
Suite
$6,902
From
US$1,025
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 31 January 2027
Visit: Colombia, Curacao, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$1,225
Oceanview
$1,375
Balcony
$1,964
Suite
$1,875
From
US$1,225
Save 645
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 12 December 2026
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,517
Oceanview
$1,767
Balcony
$1,977
Suite
$2,687
From
US$1,517
Per Person
View Trip
16 Day Panama Canal Holiday with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 December 2027
Visit: USA, Mexico, Costa Rica, Panama, Colombia
Book Early & Have It All Fare Option
Inside
$2,674
Oceanview
$2,974
Balcony
$4,974
Suite
$9,574
From
US$2,674
Per Person
View Trip
Results: 31-60 of 342

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