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All Panama Tours & Cruises

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342 Trips (1,086 Trip Departures)
11 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 09 November 2027
Visit: USA, Bahamas, Colombia, Panama, Costa Rica, Jamaica
Inside
$1,439
Oceanview
$1,739
Balcony
$2,689
Suite
$2,889
From
US$1,439
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Fare Saver
Inside
$1,899
Oceanview
$2,099
Balcony
$4,699
Suite
-
From
US$1,899
Per Person
View Trip
13 Day Miami, Fl to Lima (Callao) with Silversea
Cruise

13 Days (12 Nights) Miami to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 January 2028
Visit: USA, Mexico, Costa Rica, Panama, Ecuador, Peru
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,900
Suite
$14,700
From
US$8,900
Save 2,500
Per Person
View Trip
11 Day Spanish Lullaby with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2028
Visit: Panama, Costa Rica, Honduras, Guatemala, Mexico, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,999
Balcony
$4,799
Suite
$6,899
From
US$2,999
Save 2,999
Per Person
View Trip
20 Day Panama Canal Passage with Seabourn
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Yours to Explore
Inside
-
Oceanview
$8,999
Balcony
$11,999
Suite
$22,499
From
US$8,999
Per Person
View Trip
10 Day Belize, Costa Rica & Panama Cruise: Belize City, Puerto Limon & Panama City with Azamara Cruises
Cruise
 (5)

10 Days (9 Nights) Miami to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Azamara Always Included
Inside
$2,999
Oceanview
$3,479
Balcony
$4,159
Suite
$5,819
From
US$2,999
Per Person
View Trip
17 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

17 Days (16 Nights) Santiago to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 March 2027
Visit: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Inside
$2,299
Oceanview
$2,399
Balcony
$3,399
Suite
$4,899
From
US$2,299
Per Person
View Trip
11 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 11 December 2027
Visit: USA, Colombia, Panama, Costa Rica, Jamaica, Bahamas
Inside
$1,439
Oceanview
$1,739
Balcony
$2,689
Suite
$2,889
From
US$1,439
Per Person
View Trip
20 Day Panama Canal & the Americas with Viking Cruises
Cruise
 (1)

20 Days (19 Nights) New York to Santiago
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 25 October 2026
Visit: USA, Bahamas, Jamaica, Panama, Peru, Chile
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,995
Suite
$14,995
From
US$8,995
Save 2,000
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Miami To Los Angeles with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departures: Apr 2026 to Apr 2028
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$1,409
Oceanview
$2,309
Balcony
$2,569
Suite
$2,829
From
US$1,409
Per Person
View Trip
8 Day San Juan To Colon Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) San Juan to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 27 November 2027
Visit: Puerto Rico, Virgin Islands, Saint Martin, Saint Lucia, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$674
Oceanview
$753
Balcony
$1,223
Suite
$1,323
From
US$674
Save 396
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 22 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
Flights Included
Inside
-
Oceanview
-
Balcony
$12,495
Suite
$16,995
From
US$12,495
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,200
Suite
$18,700
From
US$13,200
Save 3,500
Per Person
View Trip
19 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

19 Days (18 Nights) Los Angeles to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 27 September 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,649
Oceanview
$1,895
Balcony
$2,857
Suite
$3,799
From
US$1,649
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Nov 2026 to Feb 2027
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,015
Oceanview
$1,085
Balcony
$1,970
Suite
$3,299
From
US$1,015
Per Person
View Trip
22 Day Seattle To Miami with Cunard
Cruise
 (13)

22 Days (21 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2026
Visit: USA, Mexico, Guatemala, Panama, Curacao, Aruba
Bonus Onboard Credit
Inside
$2,049
Oceanview
$2,149
Balcony
$3,299
Suite
$12,699
From
US$2,049
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2026 to Dec 2026
Visit: Panama, Costa Rica, Honduras, Belize, Mexico, USA
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,899
Suite
$6,499
From
US$3,899
Save 300
Per Person
View Trip
11 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Fort-de-France
Cruise Line: Ponant
Ship: Le Bellot
Departure: 08 April 2027
Visit: Panama, Colombia, Holland, Saint Lucia, Guadeloupe, Martinique
Inside
-
Oceanview
-
Balcony
$7,150
Suite
$11,330
From
US$7,150
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departures: Oct 2027 to Apr 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,399
Oceanview
$1,599
Balcony
$2,159
Suite
$3,709
From
US$1,399
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$4,299
Suite
$6,799
From
US$4,299
Per Person
View Trip
27 Day Southampton To Los Angeles with Cunard
Cruise
 (1)

27 Days (26 Nights) London to Los Angeles
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 January 2027
Visit: England, USA, Aruba, Panama, El Salvador, Mexico
Bonus Onboard Credit
Inside
$3,049
Oceanview
$4,349
Balcony
$5,429
Suite
$13,899
From
US$3,049
Per Person
View Trip
11 Day Central American Seas with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 January 2028
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,099
Oceanview
$4,099
Balcony
$4,899
Suite
$7,049
From
US$3,099
Save 3,099
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 March 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$1,899
Oceanview
$1,999
Balcony
$3,899
Suite
$8,199
From
US$1,899
Per Person
View Trip
34 Day Grand World Voyage with Holland America
Cruise

34 Days (33 Nights) Tokyo to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 14 April 2026
Visit: Japan, USA, Mexico, El Salvador, Panama, Colombia
Advantage Fare
Inside
$5,999
Oceanview
$8,144
Balcony
$15,394
Suite
-
From
US$5,999
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Dec 2026 to Dec 2026
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,205
Oceanview
$1,354
Balcony
$1,649
Suite
$2,679
From
US$1,205
Per Person
View Trip
31 Day Miami To Seattle with Cunard
Cruise
 (13)

31 Days (30 Nights) Miami to Seattle
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Mexico, Canada
Inside
-
Oceanview
-
Balcony
$3,199
Suite
-
From
US$3,199
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visit: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Book Early & Have It All Fare Option
Inside
$2,804
Oceanview
$3,104
Balcony
$3,804
Suite
$5,304
From
US$2,804
Per Person
View Trip
11 Day Canal & Coral Isles with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 April 2026
Visit: Panama, Colombia, Costa Rica, Honduras, Mexico, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$3,999
Balcony
-
Suite
-
From
US$3,999
Save 3,999
Per Person
View Trip
18 Day Panama Canal: LA to Miami Halloween with Virgin Voyages
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Virgin Voyages
Ship: Brilliant Lady
Departure: 29 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Limited Time Offer
Inside
$1,854
Oceanview
$2,363
Balcony
$2,534
Suite
$9,503
From
US$1,854
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 January 2027
Visit: USA, Mexico, Guatemala, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,899
Oceanview
$1,999
Balcony
$2,999
Suite
$4,599
From
US$1,899
Per Person
View Trip
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