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All Panama Tours & Cruises

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373 Trips (1,258 Departures)
373 Trips (1,258 Departures)
Departures
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Duration
6 Days
171 Days
Types
Budget
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Price
$1,000pp
$147,495pp
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13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Volendam
Departure: 11 December 2027
Visits: USA, Bahamas, Curacao, Colombia, Panama, Costa Rica, Cayman Islands
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,494
Oceanview
$4,108
Balcony
$5,801
Suite
$9,632
From (Per Person)
A$3,494
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Princess
Ship: Caribbean Princess
Departure: 23 December 2027
Visits: USA, Aruba, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,660
Oceanview
$2,740
Balcony
$3,670
Suite
$5,472
From (Per Person)
A$2,660
Per Person
View Trip
15 Day Fuerte Amador (Panama City) to New York with Crystal Cruises
New ReleaseCruise

15 Days (14 Nights) Panama City to New York
Operator: Crystal
Ship: Crystal Serenity
Departure: 20 August 2027
Visits: Panama, Colombia, Jamaica, Cayman Islands, USA
Exclusive Savings
Oceanview
$8,781
Balcony
$11,150
Suite
$11,238
From (Per Person)
A$8,781
Save 2,419
Per Person
View Trip
12 Day Crescent Beaches & Colorful Towns with Regent Seven Seas
Cruise

12 Days (11 Nights) Panama City to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 February 2027
Visits: Panama, Costa Rica, Honduras, Belize +5 more, Guatemala, Mexico, Cayman Islands, Jamaica, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,626
Suite
$15,952
From (Per Person)
A$15,626
Save 7,674
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operator: G Adventures
Departures: Dec 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$1,469
Save 530
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$5,489
Save 1,101
Per Person
View Trip
24 Day Caribbean & Canal Crest with Oceania Cruises
Cruise

24 Days (23 Nights) Miami to Miami
Operator: Oceania
Ship: Oceania Sonata
Departure: 30 January 2029
Visits: USA, Dominican Republic, Bonaire, Curacao +8 more, Aruba, Colombia, Costa Rica, Panama, Grenada, Dominica, Saint Kitts and Nevis, Virgin Islands
Your World Inclusions
Exclusive Savings
Balcony
$16,835
Suite
$22,781
From (Per Person)
A$16,835
Save 2,465
Per Person
View Trip
23 Day Journey To The Amazon with Regent Seven Seas
Cruise

23 Days (22 Nights) Panama City to Panama City
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 March 2027
Visits: Panama, Aruba, Trinidad and Tobago, Brazil, Grenada, Curacao
Exclusive Savings
Balcony
$34,236
Suite
$36,964
From (Per Person)
A$34,236
Save 9,064
Per Person
View Trip
138 Day Fort Lauderdale to Barcelona with Crystal Cruises
New ReleaseCruise

138 Days (137 Nights) Fort Lauderdale to Barcelona
Operator: Crystal
Ship: Crystal Symphony
Departure: 11 January 2028
Visits: USA, Mexico, Belize, Guatemala +34 more, Honduras, Costa Rica, Colombia, Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, American Samoa, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Indonesia, Philippines, Vietnam, Singapore, Malaysia, Thailand, India, Sri Lanka, Oman, United Arab Emirates, Saudi Arabia, Jordan, Egypt, Greece, Sicily, Malta, Tunisia, Italy, Spain
Exclusive Savings
Oceanview
$103,735
Balcony
$132,010
Suite
$137,860
From (Per Person)
A$103,735
Save 2,265
Per Person
View Trip
45 Day Sun, Sand & Seas Of Stars with Oceania Cruises
Cruise

45 Days (44 Nights) Los Angeles to Miami
Operator: Oceania
Ship: Oceania Sonata
Departure: 06 January 2028
Visits: USA, Mexico, Guatemala, Costa Rica +14 more, Panama, Colombia, Cayman Islands, Saint Martin, Martinique, Saint Lucia, Grenada, Aruba, Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Guadeloupe, Honduras, Belize
Your World Inclusions
Exclusive Savings
Balcony
$31,870
Suite
$43,500
From (Per Person)
A$31,870
Save 2,800
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Miami to San Diego
Operator: Holland America
Ship: Zuiderdam
Departure: 02 January 2027
Visits: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Have It All Fare Option
Exclusive Savings
Inside
$2,747
Oceanview
$2,895
Balcony
$4,232
Suite
$6,459
From (Per Person)
A$2,747
Per Person
View Trip
12 Day The Panama Canal & Costa Rica - Eastbound with Tauck
Tour + Cruise

12 Days Puntarenas to Panama City
Operator: Tauck
Cruise Line: Ponant
Ship: Le Lapérouse
Departure: 03 February 2027
Trip Styles: Coach, Cruise, Scenic
Visits: Costa Rica, Panama
Complimentary Hotel Night
From (Per Person)
A$13,999
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Orlando to Los Angeles
Operator: Princess
Ship: Star Princess
Departure: 07 April 2028
Visits: USA, Turks and Caicos Islands, Aruba, Panama, Mexico
Sanctuary Collection
Exclusive Savings
Inside
$2,779
Oceanview
$3,146
Balcony
$4,007
Suite
$5,749
From (Per Person)
A$2,779
Per Person
View Trip
28 Day Southampton To Los Angeles with Cunard
Cruise

28 Days (27 Nights) London to Los Angeles
Operator: Cunard
Ship: Queen Anne
Departure: 11 January 2028
Visits: England, Portugal, USA, Colombia, Panama, Guatemala, Mexico
Exclusive Savings
Inside
$6,780
Oceanview
$8,651
Balcony
$10,790
Suite
$19,482
From (Per Person)
A$6,780
Per Person
View Trip
18 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

18 Days (17 Nights) Los Angeles to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica +4 more, Panama, Colombia, Jamaica, Bahamas
Just Cruise Fare
Exclusive Savings
Inside
$3,968
Oceanview
$5,307
Balcony
$6,276
Suite
$6,648
From (Per Person)
A$3,968
Per Person
View Trip
13 Day Azure Islestopanama with Oceania Cruises
Cruise

13 Days (12 Nights) Miami to Panama City
Operator: Oceania
Ship: Oceania Vista
Departure: 07 January 2029
Visits: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis +4 more, Curacao, Aruba, Colombia, Panama
Your World Inclusions
Exclusive Savings
Balcony
$6,805
Suite
$11,674
From (Per Person)
A$6,805
Save 2,175
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visits: USA, Mexico, Guatemala, Belize +5 more, Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Balcony
$13,885
Suite
$14,798
From (Per Person)
A$13,885
Save 8,335
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Los Angeles to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 09 January 2028
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Just Cruise Fare
Exclusive Savings
Inside
$3,299
Oceanview
$3,970
Balcony
$4,863
Suite
$5,161
From (Per Person)
A$3,299
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise From Los Angeles To New York with Norwegian Cruise Line
Cruise

20 Days (19 Nights) Los Angeles to New York
Operator: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Just Cruise Fare
Exclusive Savings
Inside
$2,924
Oceanview
$3,668
Balcony
-
Suite
-
From (Per Person)
A$2,924
Per Person
View Trip
36 Day Miami To Sydney with Cunard
Cruise

36 Days (35 Nights) Miami to Sydney
Operator: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visits: USA, Colombia, Panama, Guatemala, Mexico, Fiji, Australia
Exclusive Savings
Inside
$9,010
Oceanview
$11,772
Balcony
$14,356
Suite
$25,909
From (Per Person)
A$9,010
Per Person
View Trip
68 Day Grand Voyage: Antarctica & South America to the Mediterranean with Scenic
New ReleaseCruise

68 Days (67 Nights) Buenos Aires to Palma de Mallorca
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 25 February 2027
Visits: Argentina, Antarctica, Chile, Peru +10 more, Ecuador, Colombia, Panama, Curacao, Saint Vincent, Saint Lucia, Barbados, Portugal, Morocco, Spain
Exclusive Savings
Balcony
$97,185
Suite
$122,670
From (Per Person)
A$97,185
Save 36,710
Per Person
View Trip
16 Day Miami To Los Angeles with Cunard
Cruise

16 Days (15 Nights) Miami to Los Angeles
Operator: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visits: USA, Colombia, Panama, Guatemala, Mexico
Exclusive Savings
Inside
$4,093
Oceanview
$5,301
Balcony
$6,499
Suite
$21,873
From (Per Person)
A$4,093
Per Person
View Trip
12 Day Pristine islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 03 April 2027
Visits: Panama, Colombia, Curacao, Saint Vincent, Saint Lucia, Barbados
Exclusive Savings
Balcony
$13,039
Suite
$15,729
From (Per Person)
A$13,039
Save 4,206
Per Person
View Trip
16 Day Fort Lauderdale to San Diego with Crystal Cruises
New ReleaseCruise

16 Days (15 Nights) Fort Lauderdale to San Diego
Operator: Crystal
Ship: Crystal Symphony
Departure: 10 June 2028
Visits: USA, Colombia, Panama, Costa Rica, Nicaragua, El Salvador, Mexico
Exclusive Savings
Oceanview
$9,281
Balcony
$11,826
Suite
$11,738
From (Per Person)
A$9,281
Save 1,919
Per Person
View Trip
16 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Tampa to Los Angeles
Operator: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 April 2027
Visits: USA, Cayman Islands, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$3,443
Oceanview
$4,439
Balcony
$10,422
Suite
-
From (Per Person)
A$3,443
Save 2,009
Per Person
View Trip
17 Day Pearls, Palapas & Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 March 2029
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,331
Suite
$15,051
From (Per Person)
A$14,331
Save 9,529
Per Person
View Trip
34 Day Fort Lauderdale to Vancouver with Crystal Cruises
New ReleaseCruise

34 Days (33 Nights) Fort Lauderdale to Vancouver
Operator: Crystal
Ship: Crystal Symphony
Departure: 10 June 2028
Visits: USA, Colombia, Panama, Costa Rica +4 more, Nicaragua, El Salvador, Mexico, Canada
Exclusive Savings
Oceanview
$20,595
Balcony
$27,088
Suite
$26,474
From (Per Person)
A$20,595
Save 4,205
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Princess
Ship: Caribbean Princess
Departure: 05 December 2026
Visits: USA, Cayman Islands, Jamaica, Colombia, Panama, Costa Rica, Bahamas
Exclusive Savings
Inside
$1,463
Oceanview
$1,463
Balcony
$2,018
Suite
$2,899
From (Per Person)
A$1,463
Per Person
View Trip
62 Day Total Central America: Two Months of Wild with G Adventures
New ReleaseTour

62 Days Mexico City to Panama City
Operator: G Adventures
Departures: Feb 2027 to Jun 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$8,829
Save 1,770
Per Person
View Trip
33 Day Vancouver to New York with Crystal Cruises
New ReleaseCruise

33 Days (32 Nights) Vancouver to New York
Operator: Crystal
Ship: Crystal Serenity
Departure: 02 August 2027
Visits: Canada, USA, Mexico, El Salvador +6 more, Nicaragua, Costa Rica, Panama, Colombia, Jamaica, Cayman Islands
Exclusive Savings
Oceanview
$21,462
Balcony
$25,323
Suite
$25,323
From (Per Person)
A$21,462
Save 4,938
Per Person
View Trip
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