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All Panama Tours & Cruises

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398 Trips (1,237 Departures)
398 Trips (1,237 Departures)
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Duration
6 Days
181 Days
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Price
$900pp
$245,249pp
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59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operator: Intrepid
Departures: Sep 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visits: Mexico, Belize, Guatemala, Honduras +4 more, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$13,730
Save 338
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Los Angeles to Miami
Operator: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 09 January 2028
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Just Cruise Fare
Exclusive Savings
Inside
$3,299
Oceanview
$3,970
Balcony
$4,565
Suite
$4,937
From (Per Person)
A$3,299
Per Person
View Trip
13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Holland America
Ship: Volendam
Departure: 11 December 2027
Visits: USA, Bahamas, Curacao, Colombia, Panama, Costa Rica, Cayman Islands
Fare Saver
Exclusive Savings
Inside
$3,494
Oceanview
$4,108
Balcony
$5,801
Suite
$9,632
From (Per Person)
A$3,494
Per Person
View Trip
16 Day Fort Lauderdale to San Diego with Crystal Cruises
New ReleaseCruise

16 Days (15 Nights) Fort Lauderdale to San Diego
Operator: Crystal
Ship: Crystal Symphony
Departure: 10 June 2028
Visits: USA, Colombia, Panama, Costa Rica, Nicaragua, El Salvador, Mexico
Exclusive Savings
Oceanview
$9,193
Balcony
$11,124
Suite
$10,510
From (Per Person)
A$9,193
Save 1,907
Per Person
View Trip
16 Day Treasures Of Two Oceans with Oceania Cruises
Cruise

16 Days (15 Nights) Miami to Los Angeles
Operator: Oceania
Ship: Oceania Vista
Departure: 06 January 2027
Visits: USA, Cayman Islands, Colombia, Panama, Guatemala, Mexico
Your World Inclusions
Exclusive Savings
Balcony
$10,317
Suite
$17,010
From (Per Person)
A$10,317
Save 2,243
Per Person
View Trip
31 Day Msc World Cruise with MSC Cruises
Cruise

31 Days (30 Nights) Los Angeles to Marseille
Operator: MSC Cruises
Ship: MSC Magnifica
Departure: 07 April 2027
Visits: USA, Mexico, Costa Rica, Panama +6 more, Dominican Republic, Virgin Islands, Saint Martin, Spain, Italy, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$20,922
From (Per Person)
A$20,922
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Princess
Ship: Caribbean Princess
Departures: Dec 2026
Visits: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Exclusive Savings
Inside
$1,496
Oceanview
$1,561
Balcony
$2,615
Suite
$4,070
From (Per Person)
A$1,496
Per Person
View Trip
13 Day Panama Canal& Island Gems with Oceania Cruises
Cruise

13 Days (12 Nights) Panama City to Miami
Operator: Oceania
Ship: Oceania Vista
Departure: 19 January 2029
Visits: Panama, Costa Rica, Cayman Islands, Jamaica +4 more, Dominican Republic, Virgin Islands, Puerto Rico, USA
Your World Inclusions
Exclusive Savings
Balcony
$6,804
Suite
$11,673
From (Per Person)
A$6,804
Save 2,176
Per Person
View Trip
12 Day Pristine islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 03 April 2027
Visits: Panama, Colombia, Curacao, Saint Vincent, Saint Lucia, Barbados
Exclusive Savings
Balcony
$13,039
Suite
$15,729
From (Per Person)
A$13,039
Save 4,206
Per Person
View Trip
11 Day Cartagena to Puntarenas with Crystal Cruises
New ReleaseCruise

11 Days (10 Nights) Cartagena to Puntarenas
Operator: Crystal
Ship: Crystal Serenity
Departure: 02 December 2026
Visits: Colombia, Curacao, Bonaire, Aruba, Panama, Costa Rica
Exclusive Savings
Oceanview
$7,155
Balcony
$8,422
Suite
$9,105
From (Per Person)
A$7,155
Save 1,145
Per Person
View Trip
30 Day Holiday Harbors & Hollywood with Oceania Cruises
Cruise

30 Days (29 Nights) Miami to Los Angeles
Operator: Oceania
Ship: Oceania Sonata
Departure: 06 December 2027
Visits: USA, Aruba, Curacao, Bonaire +11 more, Grenada, Barbados, Saint Lucia, Guadeloupe, Virgin Islands, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Inclusions
Exclusive Savings
Balcony
$19,979
Suite
$28,156
From (Per Person)
A$19,979
Save 2,501
Per Person
View Trip
27 Day Central and South American Adventure: From Costa Rica to Colombia with G Adventures
New ReleaseTour

27 Days San Jose to Medellin
Operator: G Adventures
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visits: Costa Rica, Panama, Colombia
Exclusive Savings
From (Per Person)
A$5,683
Save 802
Per Person
View Trip
15 Day Carnival Of Caribbean Colors with Regent Seven Seas
Cruise

15 Days (14 Nights) Panama City to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 31 March 2027
Visits: Panama, Colombia, Aruba, Curacao +6 more, Bonaire, Grenada, Saint Lucia, Saint Barthelemy, Virgin Islands, USA
Exclusive Savings
Balcony
$18,257
Suite
$18,962
From (Per Person)
A$18,257
Save 2,313
Per Person
View Trip
13 Day Flavors Of Cartagena with Regent Seven Seas
Cruise

13 Days (12 Nights) Miami to Panama City
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 02 March 2028
Visits: USA, Cayman Islands, Jamaica, Dominican Republic, Colombia, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,103
Suite
$16,671
From (Per Person)
A$16,103
Save 2,277
Per Person
View Trip
16 Day Miami To Los Angeles with Cunard
Cruise

16 Days (15 Nights) Miami to Los Angeles
Operator: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visits: USA, Colombia, Panama, Guatemala, Mexico
Exclusive Savings
Inside
$4,093
Oceanview
$5,301
Balcony
$6,499
Suite
$12,775
From (Per Person)
A$4,093
Per Person
View Trip
143 Day Viking World Cruise with Viking Cruises
Cruise

143 Days (142 Nights) Fort Lauderdale to London
Operator: Viking
Ship: Viking Vesta
Departures: Dec 2027 to Dec 2028
Visits: USA, Mexico, Colombia, Panama +29 more, Costa Rica, French Polynesia, Cook Islands, New Zealand, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, Seychelles, Kenya, Tanzania, Zanzibar, Madagascar, Mozambique, South Africa, Namibia, Angola, Nigeria, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Exclusive Savings
Balcony
$115,635
Suite
$195,995
From (Per Person)
A$115,635
Save 2,470
Per Person
View Trip
27 Day Azure To Iberia with Regent Seven Seas
Cruise

27 Days (26 Nights) Panama City to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 14 March 2028
Visits: Panama, Colombia, Aruba, Curacao +7 more, Grenada, Dominica, Virgin Islands, USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$34,658
Suite
$35,157
From (Per Person)
A$34,658
Save 2,622
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$9,763
From (Per Person)
A$9,763
Save 8,617
Per Person
View Trip
57 Day South America Discovery Roundtrip Fort Lauderdale with Cunard
Cruise

57 Days (56 Nights) Fort Lauderdale to Fort Lauderdale
Operator: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visits: USA, Turks and Caicos Islands, Barbados, Brazil +6 more, Uruguay, Argentina, Chile, Peru, Panama, Aruba
Exclusive Savings
Inside
$12,314
Oceanview
$16,215
Balcony
$19,561
Suite
$40,945
From (Per Person)
A$12,314
Per Person
View Trip
33 Day Around The Americas with Oceania Cruises
Cruise

33 Days (32 Nights) Montreal to Los Angeles
Operator: Oceania
Ship: Oceania Vista
Departure: 10 October 2027
Visits: Canada, Bermuda, Bahamas, USA +6 more, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Inclusions
Exclusive Savings
Balcony
$22,022
Suite
$30,528
From (Per Person)
A$22,022
Save 2,538
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Panama City to Fort Lauderdale
Operator: Viking
Ship: Viking Mars
Departures: Nov 2026 to Dec 2026
Visits: Panama, Costa Rica, Honduras, Belize, Mexico, USA
Exclusive Savings
Balcony
$5,728
From (Per Person)
A$5,728
Save 1,395
Per Person
View Trip
6 Day Panama: Sandy Beaches & San Blas Sunsets with G Adventures
New ReleaseTour

6 Days Panama City to Panama City
Operator: G Adventures
Departures: Oct 2026 to Feb 2028
Trip Styles: Adventure, Small Group, 18-30's, Short Break
Visits: Panama
Exclusive Savings
From (Per Person)
A$1,322
Save 177
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visits: Peru, Ecuador, Costa Rica, Panama +4 more, Honduras, Belize, Mexico, USA
Exclusive Savings
Balcony
$23,467
Suite
$24,173
From (Per Person)
A$23,467
Save 2,423
Per Person
View Trip
12 Day Crescent Beaches & Colorful Towns with Regent Seven Seas
Cruise

12 Days (11 Nights) Panama City to Miami
Operator: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 February 2027
Visits: Panama, Costa Rica, Honduras, Belize +5 more, Guatemala, Mexico, Cayman Islands, Jamaica, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$197,843
From (Per Person)
A$197,843
Save 5,987
Per Person
View Trip
18 Day A Grand Journey Through Balmy Shores & Enchanting Nature to Panama’s Wonders with Explora Journeys
Cruise

18 Days (17 Nights) San Juan to Panama City
Operator: Explora Journeys
Ship: Explora III
Departure: 05 April 2027
Visits: Puerto Rico, Saint Barthelemy, Montserrat, Saint Kitts and Nevis +6 more, USA, Jamaica, Curacao, Aruba, Colombia, Panama
Exclusive Savings
Suite
$20,751
From (Per Person)
A$20,751
Save 424
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operator: Intrepid
Departures: Aug 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visits: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From (Per Person)
A$4,778
Save 1,317
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Operator: Princess
Ship: Star Princess
Departure: 27 September 2026
Visits: Canada, USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$3,577
Oceanview
$4,660
Balcony
$5,811
Suite
$8,722
From (Per Person)
A$3,577
Per Person
View Trip
13 Day Miami, Fl to Lima (Callao) with Silversea
Cruise

13 Days (12 Nights) Miami to Lima
Operator: Silversea
Ship: Silver Ray
Departure: 15 January 2028
Visits: USA, Mexico, Costa Rica, Panama, Ecuador, Peru
Exclusive Savings
Balcony
$12,348
Suite
$25,676
From (Per Person)
A$12,348
Save 5,652
Per Person
View Trip
13 Day Azure Islestopanama with Oceania Cruises
Cruise

13 Days (12 Nights) Miami to Panama City
Operator: Oceania
Ship: Oceania Vista
Departure: 07 January 2029
Visits: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis +4 more, Curacao, Aruba, Colombia, Panama
Your World Inclusions
Exclusive Savings
Balcony
$6,805
Suite
$11,674
From (Per Person)
A$6,805
Save 2,175
Per Person
View Trip
12 Day Fuerte Amador (Panama City) to Fort Lauderdale with Crystal Cruises
New ReleaseCruise

12 Days (11 Nights) Panama City to Fort Lauderdale
Operator: Crystal
Ship: Crystal Serenity
Departure: 11 December 2027
Visits: Panama, Costa Rica, Honduras, Guatemala, Belize, Mexico, USA
Exclusive Savings
Oceanview
$6,451
Balcony
$7,591
Suite
$8,381
From (Per Person)
A$6,451
Save 1,649
Per Person
View Trip
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