Home > Tours > Latin America Tours > Central America Tours > Panama Tours & Cruises > All Trips

All Panama Tours & Cruises

Filter Results
Departures
Show More...
Duration
6 Days
181 Days
Types
Budget
Start & End Cities
Operators
Show More...
Price
$400pp
$177,598pp
Countries
Show More...
Filter Results
342 Trips (1,086 Trip Departures)
27 Day Los Angeles To Southampton with Cunard
Cruise
 (13)

27 Days (26 Nights) Los Angeles to London
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba, Portugal, England
Inside
$4,879
Oceanview
$5,679
Balcony
$7,179
Suite
$16,879
From
US$4,879
Per Person
View Trip
11 Day Panama & Pristine Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas, USA
Your World Inclusions
Exclusive Savings
Inside
$3,099
Oceanview
$3,999
Balcony
$4,599
Suite
$6,399
From
US$3,099
Save 3,099
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) San Diego to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 13 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Inside
$2,139
Oceanview
$2,609
Balcony
$3,859
Suite
$4,459
From
US$2,139
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (5)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Inside
$6,129
Oceanview
$6,609
Balcony
$7,499
Suite
$12,339
From
US$6,129
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,399
Oceanview
$2,499
Balcony
$3,899
Suite
$6,699
From
US$2,399
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,304
Oceanview
$2,394
Balcony
$3,784
Suite
$6,564
From
US$2,304
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise
 (3)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 02 October 2026
Visit: USA, Mexico, Guatemala, El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,629
Oceanview
$1,689
Balcony
$2,759
Suite
$4,939
From
US$1,629
Per Person
View Trip
13 Day Flavors Of Cartagena with Regent Seven Seas
Cruise

13 Days (12 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 02 March 2028
Visit: USA, Cayman Islands, Jamaica, Dominican Republic, Colombia, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,799
Suite
$12,199
From
US$11,799
Save 11,799
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Gem, Norwegian Sun
Departures: Nov 2026 to Nov 2027
Visit: USA, Bahamas, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Inside
$1,519
Oceanview
$1,689
Balcony
$2,339
Suite
$3,119
From
US$1,519
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 07 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$2,149
Oceanview
$2,449
Balcony
$3,199
Suite
$3,449
From
US$2,149
Per Person
View Trip
13 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (2)

13 Days (12 Nights) Fort-de-France to Colon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 07 December 2026
Visit: Martinique, Guadeloupe, Saint Lucia, Saint Vincent, Holland, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$8,960
Suite
$14,210
From
US$8,960
Per Person
View Trip
19 Day Transamerican Treasures with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,899
Suite
$12,099
From
US$6,899
Save 6,899
Per Person
View Trip
23 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

23 Days (22 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 23 December 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Inside
$2,968
Oceanview
$3,288
Balcony
$4,098
Suite
-
From
US$2,968
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Jan 2027 to Jan 2028
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Inside
$998
Oceanview
$1,158
Balcony
$1,463
Suite
$4,583
From
US$998
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (3)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$1,924
Oceanview
$1,984
Balcony
$3,264
Suite
$6,204
From
US$1,924
Per Person
View Trip
13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise
 (3)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departures: Oct 2026 to Mar 2027
Visit: USA, Bahamas, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Fare Saver
Inside
$1,199
Oceanview
$1,349
Balcony
$1,899
Suite
$3,999
From
US$1,199
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$2,661
Oceanview
$3,007
Balcony
$4,577
Suite
$5,913
From
US$2,661
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sun
Departures: Dec 2026 to Apr 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico
Inside
$1,649
Oceanview
$1,669
Balcony
$2,309
Suite
$3,509
From
US$1,649
Per Person
View Trip
13 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (1)

13 Days (12 Nights) Fort-de-France to Colon
Cruise Line: Ponant
Ship: Le Bellot
Departure: 26 October 2026
Visit: Martinique, Guadeloupe, Saint Lucia, Saint Vincent, Bonaire, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$7,550
Suite
$11,910
From
US$7,550
Per Person
View Trip
36 Day World Cruise: Panama Canal Crossing & Polynesia with Seabourn
Cruise
 (1)

36 Days (35 Nights) Miami to Tahiti
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru, Chile, Easter Island, French Polynesia
Yours to Explore
Inside
-
Oceanview
$20,099
Balcony
$22,599
Suite
$45,099
From
US$20,099
Per Person
View Trip
17 Day Halcyon Holidays with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 19 December 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$11,899
From
US$8,299
Save 8,299
Per Person
View Trip
15 Day Aruba, Colombia & Panama Cruise: Oranjestad, Cartagena & Panama City with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Miami to Lima
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 January 2028
Visit: USA, Aruba, Curacao, Colombia, Panama, Ecuador, Peru
Azamara Always Included
Inside
$4,189
Oceanview
$4,669
Balcony
$5,399
Suite
$8,329
From
US$4,189
Per Person
View Trip
15 Day Panama Canal & Central America with Viking Cruises
Cruise
 (8)

15 Days (14 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2026 to Feb 2028
Visit: USA, Jamaica, Panama, Costa Rica, Honduras, Belize, Mexico
Flights Included
Viking $499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,299
Suite
$7,999
From
US$5,299
Save 1,000
Per Person
View Trip
12 Day Grenadines, Colombia & Panama Canal transit with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Bridgetown to Panama City
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 13 January 2028
Visit: Barbados, Saint Vincent, Bonaire, Curacao, Aruba, Colombia, Panama
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$10,296
Balcony
-
Suite
$12,771
From
US$10,296
Save 1,999
Per Person
View Trip
28 Day Southampton To Los Angeles with Cunard
Cruise

28 Days (27 Nights) London to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 11 January 2028
Visit: England, Portugal, USA, Colombia, Panama, Guatemala, Mexico
Inside
$5,389
Oceanview
$6,689
Balcony
$8,089
Suite
$15,789
From
US$5,389
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise From Los Angeles To New York with Norwegian Cruise Line
Cruise

20 Days (19 Nights) Los Angeles to New York
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$2,029
Oceanview
$2,199
Balcony
$2,549
Suite
$3,049
From
US$2,029
Per Person
View Trip
15 Day Panama Canal To Machu Picchu with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia, Panama, Ecuador, Peru
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$4,399
Oceanview
$4,799
Balcony
$6,199
Suite
$8,799
From
US$4,399
Save 4,399
Per Person
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departures: Jan 2027 to Mar 2027
Visit: USA, Mexico, Belize, Guatemala, Honduras, Costa Rica, Panama
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,899
Balcony
$4,275
Suite
$5,940
From
US$2,999
Save 3,149
Per Person
View Trip
17 Day Ultimate Panama Canal Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 24 January 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,399
Suite
$18,399
From
US$17,399
Save 17,399
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Bonus Onboard Credit
Exclusive Savings
Inside
$1,777
Oceanview
$2,216
Balcony
$3,019
Suite
$5,539
From
US$1,777
Save 716
Per Person
View Trip
Results: 151-180 of 342

No trips found. Try adjusting the search filters.




Trips found! Scroll up to view.

Central America Tours

All Central America Tours Belize Tours Chile Trips Colombia Trips Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours Peru Trips

Travel Styles

18-30's Tours Active Adventures Coach Tours Cycling Tours Festivals & Events Luxury Tours Short Breaks Small Group Tours Wildlife Tours

Trip Lengths

1 Month 10 Day 2 Week 3 Week 4 Week 7 Day

Departure Months

April May June July August September October November December January February March

Cities

Tours from Lima Tours from San Jose Tours from Santiago Tours from Santiago

Routes

Tours from Auckland to Auckland Tours from Barcelona to Lisbon Tours from Cape Town to Cape Town Tours from Lima to Lima Tours from Lima to Buenos Aires Tours from London to Rome Tours from London to London Tours from Los Angeles to San Francisco Tours from Los Angeles to Los Angeles Tours from New York to Los Angeles Tours from New York to New York Tours from Perth to Perth Tours from Rome to London Tours from Rome to Rome Tours from San Francisco to Los Angeles Tours from San Francisco to San Francisco Tours from San Jose to San Jose Tours from Santiago to Buenos Aires Tours from Sydney to Perth Tours from Sydney to Sydney Tours from Vancouver to Vancouver

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations