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All Panama Tours & Cruises

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356 Trips (1,151 Trip Departures)
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Santiago
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 06 November 2026
Visit: USA, Mexico, Panama, Ecuador, Peru, Chile
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,495
Suite
$14,995
From
US$9,495
Save 500
Per Person
View Trip
25 Day Central American Explorer with Explore Worldwide
Tour

25 Days Panama City to Antigua
Operated By: Explore Worldwide
Departures: Feb 2026 to Nov 2026
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama, Guatemala, Honduras, El Salvador, Nicaragua
Exclusive Savings
From
US$4,957
Save 1,063
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Nov 2026 to Mar 2027
Visit: USA, Colombia, Panama, Aruba, Curacao, Bonaire
Exclusive Savings
Inside
$2,259
Oceanview
$2,387
Balcony
$4,256
Suite
$8,272
From
US$2,259
Save 1,314
Per Person
View Trip
19 Day Panama Canal Cruise From Miami To San Francisco with Norwegian Cruise Line
Cruise

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Encore
Departure: 11 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$1,849
Oceanview
$2,049
Balcony
$2,089
Suite
$2,349
From
US$1,849
Per Person
View Trip
34 Day Grand World Voyage with Holland America
Cruise

34 Days (33 Nights) Tokyo to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 14 April 2026
Visit: Japan, USA, Mexico, El Salvador, Panama, Colombia
Advantage Fare
Exclusive Savings
Inside
$5,925
Oceanview
$7,395
Balcony
$15,132
Suite
-
From
US$5,925
Per Person
View Trip
13 Day Caribbean with Costa Rica & Panama Canal Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Dec 2026 to Dec 2026
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,192
Oceanview
$1,252
Balcony
$1,592
Suite
$2,602
From
US$1,192
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 23 December 2027
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,449
Oceanview
$1,749
Balcony
$2,149
Suite
$2,749
From
US$1,449
Per Person
View Trip
11 Day A Journey Through Enchanting Nature & The Marvels Of The Panama Canal with Explora Journeys
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Visit: USA, Jamaica, Curacao, Aruba, Colombia, Panama
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$7,465
Suite
$7,870
From
US$7,465
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sun
Departures: Dec 2026 to Apr 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico
Inside
$1,689
Oceanview
$1,849
Balcony
$2,527
Suite
$3,711
From
US$1,689
Per Person
View Trip
11 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (2)

11 Days (10 Nights) Colon to Fort-de-France
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 12 March 2027
Visit: Panama, Colombia, Bonaire, Saint Vincent, Saint Lucia, Guadeloupe, Martinique
Inside
-
Oceanview
-
Balcony
$6,760
Suite
$10,670
From
US$6,760
Per Person
View Trip
15 Day Panama Canal & Central America with Viking Cruises
Cruise
 (8)

15 Days (14 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2026 to Feb 2028
Visit: USA, Jamaica, Panama, Costa Rica, Honduras, Belize, Mexico
Flights Included
Viking $499 Air Deal
Inside
-
Oceanview
-
Balcony
$5,099
Suite
$7,999
From
US$5,099
Per Person
View Trip
12 Day Grenadines, Colombia & Panama Canal transit with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Bridgetown to Panama City
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 13 January 2028
Visit: Barbados, Saint Vincent, Bonaire, Curacao, Aruba, Colombia, Panama
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$10,249
Balcony
-
Suite
$12,917
From
US$10,249
Save 12,741
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 07 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$2,249
Oceanview
$2,299
Balcony
$2,707
Suite
$3,308
From
US$2,249
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 09 April 2027
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
$2,482
Oceanview
$3,016
Balcony
$3,889
Suite
$4,568
From
US$2,482
Save 57
Per Person
View Trip
19 Day Panama Canal Cruise: Colombia, Costa Rica & Mexico with Azamara Cruises
Cruise
 (4)

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 18 December 2026
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Azamara Always Included
Exclusive Savings
Inside
$4,786
Oceanview
$5,503
Balcony
$5,998
Suite
$9,733
From
US$4,786
Save 93
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise From Los Angeles To New York with Norwegian Cruise Line
Cruise

20 Days (19 Nights) Los Angeles to New York
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Exclusive Savings
Inside
$2,387
Oceanview
$2,998
Balcony
$3,124
Suite
$4,143
From
US$2,387
Save 52
Per Person
View Trip
36 Day Miami To Sydney with Cunard
Cruise

36 Days (35 Nights) Miami to Sydney
Cruise Line: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visit: USA, Colombia, Panama, Guatemala, Mexico, Fiji, Australia
Exclusive Savings
Inside
$6,749
Oceanview
$8,432
Balcony
$10,412
Suite
$20,411
From
US$6,749
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,036
Suite
$10,771
From
US$10,036
Save 17,362
Per Person
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 04 April 2026
Visit: Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands, USA
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,720
Oceanview
$2,939
Balcony
$4,152
Suite
-
From
US$2,720
Save 4,078
Per Person
View Trip
11 Day Panama & Pristine Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$3,046
Oceanview
$3,822
Balcony
$4,404
Suite
$6,344
From
US$3,046
Save 3,152
Per Person
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 16 January 2028
Visit: Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$3,043
Oceanview
$4,013
Balcony
$4,789
Suite
$6,729
From
US$3,043
Save 3,155
Per Person
View Trip
18 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 13 April 2026
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
$1,940
Oceanview
-
Balcony
-
Suite
-
From
US$1,940
Save 989
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (2)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 10 April 2026
Visit: USA, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Have It All Fare Option
Inside
$2,084
Oceanview
$2,494
Balcony
$3,134
Suite
$4,612
From
US$2,084
Per Person
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departures: Jan 2027 to Mar 2027
Visit: USA, Mexico, Belize, Guatemala, Honduras, Costa Rica, Panama
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,775
Balcony
$4,405
Suite
$6,345
From
US$2,999
Save 3,099
Per Person
View Trip
17 Day Panama Canal Coastlines with Oceania Cruises
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 January 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,389
Suite
$11,493
From
US$8,389
Save 8,809
Per Person
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (4)

24 Days (23 Nights) Vancouver to New York
Cruise Line: Princess
Ship: Coral Princess
Departure: 22 September 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$2,602
Oceanview
$2,702
Balcony
$4,007
Suite
$5,183
From
US$2,602
Per Person
View Trip
27 Day Los Angeles To Southampton with Cunard
Cruise
 (13)

27 Days (26 Nights) Los Angeles to London
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba, Portugal, England
Inside
$4,879
Oceanview
$5,679
Balcony
$7,121
Suite
$17,021
From
US$4,879
Per Person
View Trip
13 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (1)

13 Days (12 Nights) Fort-de-France to Colon
Cruise Line: Ponant
Ship: Le Bellot
Departure: 26 October 2026
Visit: Martinique, Guadeloupe, Saint Lucia, Saint Vincent, Bonaire, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$7,550
Suite
$11,910
From
US$7,550
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Jan 2027 to Jan 2028
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$1,046
Oceanview
$1,166
Balcony
$1,463
Suite
$4,455
From
US$1,046
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Nov 2026 to Mar 2028
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$946
Oceanview
$1,066
Balcony
$1,366
Suite
$3,770
From
US$946
Per Person
View Trip
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